Cyclooxygenase-2 Immunoreactivity and protein level in the gerbil hippocampus during normal aging

Neurochemical Research

Volumn 35, Issue 1, 2010, Pages 99-106

  Lee, Choong Hyun ^a   Yoo, Ki Yeon ^a   Choi, Jung Hoon ^a   Park, Ok Kyu ^a   Hwang, In Koo ^b   Kang, Il Jun ^a   Won, Moo Ho ^a  

^a Hallym University   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Aging; Cyclooxygenase 2; Gerbil; Hippocampus

Indexed keywords

CYCLOOXYGENASE 2;

AGED; AGING; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENTATE GYRUS; GERBIL; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING;

AGING; ANIMALS; BLOTTING, WESTERN; CYCLOOXYGENASE 2; GERBILLINAE; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; NERVE TISSUE PROTEINS;

GERBILLINAE;

EID: 76849088758     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-009-0034-5     Document Type: Article

References (37)

1. JR Vane YS Bakhle RM Botting 1998 Cyclooxygenases 1 and 2 Annu Rev Pharmacol Toxicol 38 97 120 10.1146/annurev.pharmtox.38.1.97 1:CAS:528:DyaK1cXivF2itro%3D 9597150
2. NG Bazan RJ Flower 2002 Medicine: lipid signals in pain control Nature 420 135 138 10.1038/420135a 1:CAS:528:DC%2BD38Xos1Gnsro%3D 12432374 (Pubitemid 35340106)
3. NV Chandrasekharan H Dai KL Roos, et al. 2002 COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression Proc Natl Acad Sci USA 99 13926 13931 10.1073/pnas.162468699 1:CAS:528:DC%2BD38XotVKmurc%3D 12242329 (Pubitemid 35215482)
4. HJ Lee RN Ertley SI Rapoport, et al. 2008 Chronic administration of lamotrigine downregulates COX-2 mRNA and protein in rat frontal cortex Neurochem Res 33 861 866 10.1007/s11064-007-9526-3 18080190
5. MK O'Banion 1999 Cyclooxygenase-2: molecular biology, pharmacology, and neurobiology Crit Rev Neurobiol 13 45 82 10223523
6. CD Breder D Dewitt RP Kraig 1995 Characterization of inducible cyclooxygenase in rat brain J Comp Neurol 355 296 315 10.1002/cne.903550208 1:CAS:528:DyaK2MXlvFCru70%3D 7608344
7. K Yamagata KI Andreasson WE Kaufmann, et al. 1993 Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids Neuron 11 371 386 10.1016/0896-6273(93)90192-T 1:CAS:528:DyaK2cXht1Ghu7k%3D 8352945 (Pubitemid 23250354)
8. WE Kaufmann PF Worley J Pegg, et al. 1996 Cox-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex Proc Natl Acad Sci USA 93 2317 2321 10.1073/pnas.93.6.2317 1:CAS:528:DyaK28XhvVSktr0%3D 8637870 (Pubitemid 26104347)
9. RI Galvão JP Diógenes GC Maia, et al. 2005 Tenoxicam exerts a neuroprotective action after cerebral ischemia in rats Neurochem Res 30 39 46 10.1007/s11064-004-9684-5 15756931 (Pubitemid 40254203)
10. C Iadecola K Niwa S Nogawa, et al. 2001 Reduced susceptibility to ischemic brain injury and N-methyl-d-aspartate-mediated neurotoxicity in cyclooxygenase-2 deficient mice Proc Natl Acad Sci USA 98 1294 1299 10.1073/pnas.98.3.1294 1:CAS:528:DC%2BD3MXht1SmtLc%3D 11158633 (Pubitemid 32121226)
11. M Nakayama K Uchimura RL Zhu, et al. 1998 Cyclooxygenase-2 inhibitions prevents delayed death of CA1 hippocampal neurons following global ischemia Proc Natl Acad Sci USA 95 10954 10959 10.1073/pnas.95.18.10954 1:CAS:528: DyaK1cXlvFWns78%3D 9724811 (Pubitemid 28413175)
12. E Candelario-Jalil A Gonzalez-Falcon M Garcia-Cabrera, et al. 2003 Assessment of the relative contribution of COX-1 and COX-2 isoforms to ischemia-induced oxidative damage and neurodegeneration following transient global cerebral ischemia J Neurochem 86 545 555 10.1046/j.1471-4159.2003.01812.x 1:CAS:528:DC%2BD3sXlvF2ntb8%3D 12859668 (Pubitemid 36897435)
13. V Colangelo WC Gordon PK Mukherjee, et al. 2004 Downregulation of COX-2 and JNK expression after induction of ischemic tolerance in the gerbil brain Brain Res 1016 195 200 10.1016/j.brainres.2004.05.017 1:CAS:528: DC%2BD2cXlsFOqu78%3D 15246855 (Pubitemid 38887702)
14. KY Yoo IK Hwang JD Kim, et al. 2008 Antiinflammatory effect of the ethanol extract of Berberis koreana in a gerbil model of cerebral ischemia/reperfusion Phytother Res 22 1527 1532 10.1002/ptr.2527 18688884 (Pubitemid 352789624)
15. P Casolini A Catalani AR Zuena, et al. 2002 Inhibition of COX-2 reduces the age-dependent increase of hippocampal inflammatory markers, corticosterone secretion, and behavioral impairments in the rat J Neurosci Res 68 337 343 10.1002/jnr.10192 1:CAS:528:DC%2BD38XjslSis74%3D 12111864
16. D Linnemann T Skarsfelt 1994 Regional changes in expression of NCAM, GFAP, and S100 in aging rat brain Neurobiol Aging 15 651 655 10.1016/0197-4580(94)00060-3 1:CAS:528:DyaK2MXptFymsw%3D%3D 7824058 (Pubitemid 24287338)
17. JG Sheng RE Mrak CR Rovnaghi, et al. 1996 Human brain S100 beta and S100 beta mRNA expression increases with age: pathogenic implications for Alzheimer's disease Neurobiol Aging 17 359 363 10.1016/0197-4580(96)00037-1 1:CAS:528:DyaK28Xkt1Wjtr0%3D 8725896 (Pubitemid 26200412)
18. Loskota WA, Lomax P, Verity MA (1974) A stereotaxic atlas of the Mongolian Gerbil Brain (Meriones unguiculatus). Ann Arbor Science Publishers Inc, Michigan
19. DY Li P Hardy D Abran, et al. 1997 Key role for cyclooxygenase-2 in PGE2 and PGF2alpha receptor regulation and cerebral blood flow of the newborn Am J Physiol 273 R1283 R1290 1:CAS:528:DyaK2sXnt1Squ7k%3D 9362291
20. GM Pasinetti 1998 Cyclooxygenase and inflammation in Alzheimer's disease: experimental approaches and clinical interventions J Neurosci Res 54 1 6 10.1002/(SICI)1097-4547(19981001)54:1<1::AID-JNR1>3.0.CO;2-M 1:CAS:528:DyaK1cXmt1ynu7w%3D 9778144 (Pubitemid 28447183)
21. G Tocco J Freire-Moar SS Schreiber, et al. 1997 Maturational regulation and regional induction of cyclooxygenase-2 in rat brain: implications for Alzheimer's disease Exp Neurol 144 339 349 10.1006/exnr.1997.6429 1:CAS:528:DyaK2sXjtlOjuro%3D 9168834 (Pubitemid 27224561)
22. E Sanguino N Roglans M Alegret, et al. 2004 Prevention of age-related changes in rat cortex transcription factor activator protein-1 by hypolipidemic drugs Biochem Pharmacol 68 1411 1421 10.1016/j.bcp.2004.06.008 1:CAS:528:DC%2BD2cXntlemt7o%3D 15345331 (Pubitemid 39179399)
23. BS Baek JW Kim JH Lee, et al. 2001 Age-related increase of brain cyclooxygenase activity and dietary modulation of oxidative status J Gerontol A Biol Sci Med Sci 56 B426 B431 1:STN:280:DC%2BD3Mrjs1Ghtg%3D%3D 11584027
24. 2 and cyclooxygenase-2 in Rhesus monkey brain as a function of age Brain Res Bull 69 614 621 10.1016/j. brainresbull.2006.03.006 1:CAS:528:DC%2BD28XkvVOks7o%3D 16716827 (Pubitemid 44250798)
25. K Fujimi K Noda K Sasaki, et al. 2007 Altered expression of COX-2 in subdivisions of the hippocampus during aging and in Alzheimer's disease: the Hisayama Study Dement Geriatr Cogn Disord 23 423 431 10.1159/000101957 1:CAS:528:DC%2BD2sXmt1Sqsbg%3D 17457030 (Pubitemid 46897180)
26. MG Hayek C Mura D Wu, et al. 1997 Enhanced expression of inducible cyclooxygenase with age in murine macrophages J Immunol 159 2445 2451 1:CAS:528:DyaK2sXlslKit7c%3D 9278337
27. JJ Hoozemans AJ Rozemuller I Janssen, et al. 2001 Cyclooxygenase expression in microglia and neurons in Alzheimer's disease and control brain Acta Neuropathol 101 2 8 1:CAS:528:DC%2BD3MXhtValtbc%3D 11194936
28. HJ Kim KW Kim BP Yu, et al. 2000 The effect of age on cyclooxygenase-2 gene expression: NF-kappaB activation and IkappaBalpha degradation Free Radic Biol Med 28 683 692 10.1016/S0891-5849(99)00274-9 1:CAS:528:DC%2BD3cXit1Wmsrs%3D 10754263 (Pubitemid 30171281)
29. GM Pasinetti PS Aisen 1998 Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain Neuroscience 87 319 324 10.1016/S0306-4522(98)00218-8 1:CAS:528:DyaK1cXlsV2jtr4%3D 9740394 (Pubitemid 28370892)
30. WJ Lukiw NG Bazan 1998 Strong nuclear factor-kappaB-DNA binding parallels cyclooxygenase-2 gene transcription in aging and in sporadic Alzheimer's disease superior temporal lobe neocortex J Neurosci Res 53 583 592 10.1002/(SICI)1097-4547(19980901)53:5<583::AID-JNR8>3.0.CO;2-5 1:CAS:528:DyaK1cXlsFOmt7w%3D 9726429 (Pubitemid 28380799)
31. WF Stewart C Kawas M Corrada, et al. 1997 Risk of Alzheimer's disease and duration of NSAID use Neurology 48 626 632 1:STN:280:DyaK2s3hslyktA%3D%3D 9065537
32. S Doré T Otsuka T Mito, et al. 2003 Neuronal overexpression of cyclooxygenase-2 increases cerebral infarction Ann Neurol 54 155 162 10.1002/ana.10612 12891667 (Pubitemid 36909614)
33. C Iadecola C Forster S Nogawa, et al. 1999 Cyclooxygenase-2 immunoreactivity in the human brain following cerebral ischemia Acta Neuropathol 98 9 14 10.1007/s004010051045 1:CAS:528:DyaK1MXjtleksbk%3D 10412795 (Pubitemid 29278303)
34. S Miettinen FR Fusco J Yrjänheikki, et al. 1997 Spreading depression and focal brain ischemia induce cyclooxygenase-2 in cortical neurons through N-methyl-d-aspartic acid-receptors and phospholipase A2 Proc Natl Acad Sci USA 94 6500 6505 10.1073/pnas.94.12.6500 1:CAS:528:DyaK2sXjvFGgtL4%3D 9177247 (Pubitemid 27270714)
35. S Nogawa F Zhang ME Ross, et al. 1997 Cyclo-oxygenase-2 gene expression in neurons contributes to ischemic brain damage J Neurosci 17 2746 2755 1:CAS:528:DyaK2sXisValtb4%3D 9092596
36. H Yao S Sadoshima H Ooboshi, et al. 1991 Age-related vulnerability to cerebral ischemia in spontaneously hypertensive rats Stroke 22 1414 1418 1:STN:280:DyaK38%2Fos12qug%3D%3D 1750050
37. KY Yoo IK Hwang WS Eum, et al. 2006 Differential effects and changes of ceruloplasmin in the hippocampal CA1 region between adult and aged gerbils after transient cerebral ischemia Neurosci Res 55 134 141 10.1016/j.neures.2006.02. 009 1:CAS:528:DC%2BD28XksVaisr0%3D 16542745 (Pubitemid 44275073)