Intracellular fate of bioresponsive poly(amidoamine)s in vitro and in vivo

Journal of Controlled Release

Volumn 142, Issue 1, 2010, Pages 78-88

  Richardson, Simon C W ^a   Pattrick, Nicola G ^b   Lavignac, Nathalie ^c   Ferruti, Paolo ^d   Duncan, Ruth ^a  

^a UNIVERSITY OF GREENWICH   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c MEDWAY SCHOOL OF PHARMACY   (United Kingdom)

^d UNIVERSITY OF MILAN   (Italy)

Author keywords

Endosomolytic polymer; Poly(amidoamine); Subcellular fractionation

Indexed keywords

BUOYANT DENSITY; CELL UPTAKE; CELLULAR UPTAKE; CYTOSOLIC FRACTIONS; DOSE-DEPENDENT MANNER; ENDOCYTIC PATHWAYS; IN-VITRO; IN-VIVO; INTRACELLULAR TRAFFICKING; LIVER CELLS; PH-DEPENDENT; POLY(AMIDO AMINE); SUBCELLULAR FRACTIONATION; TEM;

CELLS;

LIVER;

IODINE 125; N ACETYL BETA GLUCOSAMINIDASE; POLYAMIDOAMINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL FATE; CELL FRACTIONATION; CELL MEMBRANE PERMEABILITY; CELL TRANSPORT; CELL VACUOLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; ENDOCYTOSIS; ENZYME RELEASE; FLUORESCENCE MICROSCOPY; GEL PERMEATION CHROMATOGRAPHY; GENE TARGETING; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; LIVER CELL; MALE; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RADIOACTIVITY; RAT; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; CELL LINE; CELL MEMBRANE PERMEABILITY; ENDOCYTOSIS; HEPATOCYTES; MALE; MOLECULAR STRUCTURE; POLYAMINES; RATS; RATS, WISTAR;

EID: 76749144992     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2009.09.025     Document Type: Article

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