Characterising the size and shape of polyamidoamines in solution as a function of pH using neutron scattering and pulsed-gradient spin-echo NMR

International Journal of Pharmaceutics

Volumn 317, Issue 2, 2006, Pages 175-186

  Khayat, Zeena ^a,b   Griffiths, Peter C ^b   Grillo, Isabelle ^c   Heenan, Richard K ^d   King, Stephen M ^d   Duncan, Ruth ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c INSTITUT LAUE LANGEVIN   (France)

^d RUTHERFORD APPLETON LABORATORY   (United Kingdom)

Author keywords

Endosomolytic polymers; Polyamidoamines; Polymer therapeutics; Pulsed gradient spin echo NMR; Small angle neutron scattering

Indexed keywords

CHLORIDE; ISA 23; POLYAMIDOAMINE; UNCLASSIFIED DRUG;

ACIDITY; ARTICLE; DATA ANALYSIS; DIFFUSION COEFFICIENT; DRUG CONFORMATION; DRUG DELIVERY SYSTEM; DRUG STRUCTURE; ENDOCYTOSIS; MOLECULAR MODEL; NEUTRON SCATTERING; NORMAL DISTRIBUTION; NUCLEAR MAGNETIC RESONANCE; PH; PRIORITY JOURNAL; TEMPERATURE DEPENDENCE; VISCOSITY;

HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; NEUTRON DIFFRACTION; PIPERAZINES; POLYAMINES;

EID: 33745204644     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.03.003     Document Type: Article

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