Effects of mushroom-derived β-glucan-rich polysaccharide extracts on nitric oxide production by bone marrow-derived macrophages and nuclear factor-κb transactivation in Caco-2 reporter cells: Can effects be explained by structure?

Molecular Nutrition and Food Research

Volumn 54, Issue 2, 2010, Pages 268-276

  Volman, Julia J ^a   Helsper, Johannes P F G ^b   Wei, Song ^b   Baars, Johan J P ^b   van Griensven, Leo J L D ^b   Sonnenberg, Anron S M ^b   Mensink, Ronald P ^a   Plat, Jogchum ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Bone marrow derived macrophages; Dietary; Immune response; Intestinal epithelial cells; Mushroom

Indexed keywords

BETA GLUCAN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOLOGIC FACTOR; NITRIC OXIDE; POLYSACCHARIDE;

AGARICALES; ANIMAL; ARTICLE; BONE MARROW CELL; C57BL MOUSE; CELL CULTURE; CELL STRAIN CACO 2; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; FUNCTIONAL FOOD; GENETICS; HUMAN; IMMUNOLOGY; IMMUNOMODULATION; INTESTINE CELL; ISOLATION AND PURIFICATION; MACROPHAGE; MACROPHAGE ACTIVATION; METABOLISM; MOUSE; PHYSIOLOGY; REPORTER GENE; SPECIES DIFFERENCE; STRUCTURE ACTIVITY RELATION; TRANSCRIPTION INITIATION;

AGARICALES; ANIMALS; BETA-GLUCANS; BONE MARROW CELLS; CACO-2 CELLS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENTEROCYTES; FUNCTIONAL FOOD; GENES, REPORTER; HUMANS; IMMUNOLOGIC FACTORS; IMMUNOMODULATION; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, INBRED C57BL; MOLECULAR STRUCTURE; NF-KAPPA B; NITRIC OXIDE; POLYSACCHARIDES; SPECIES SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTIONAL ACTIVATION;

AGARICUS BISPORUS; BACTERIA (MICROORGANISMS); BASIDIOMYCOTA; COPRINUS; COPRINUS COMATUS; GANODERMA LUCIDUM; INONOTUS LINTEUS; MUS;

EID: 76749139079     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.200900009     Document Type: Article

References (35)

1. Wasser, S. P., Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides. Appl. Microbiol. Biotechnol. 2002, 60, 258-274.
2. Borchers, A. T., Keen, C. L., Gershwin, M. E., Mushrooms, tumors, and immunity: an update. Exp. Biol. Med. (Maywood) 2004, 229, 393-406.
3. Chen, J., Seviour, R., Medicinal importance of fungal beta-(13), (16)-glucans. Mycol. Res. 2007, 111, 635-652.
4. Lull, C., Wichers, H. J., Savelkoul, H. F., Antiinflammatory and immunomodulating properties of fungal metabolites. Mediators Inflamm. 2005, 2005, 63-80.
5. Wei, S., Helsper, J. P. F. G., Van Griensven, L. J. L. D., Phenolic compounds present in medicinal mushroom extracts generate reactive oxygen species in human cells in vitro. Int. J. Med. Mush. 2008, 10, 1-13.
6. Brown, G. D., Herre, J., Williams, D. L., Willment, J. A. et al. Dectin-1 mediates the biological effects of beta-glucans. J. Exp. Med. 2003, 197, 1119-1124.
7. Shamtsyan, M., Konusova, V., Maksimova, Y., Goloshchev, A., et al. Immunomodulating and anti-tumor action of extracts of several mushrooms. J. Biotechnol. 2004, 113, 77-83.
8. Hong, F., Yan, J., Baran, J. T., Allendorf, D. J. et al. Mechanism by which orally administered beta-1,3-glucans enhance the tumoricidal activity of antitumor monoclonal antibodies in murine tumor models. J. Immunol. 2004, 173, 797-806.
9. Rice, P. J., Adams, E. L., Ozment-Skelton, T., Gonzales, A. et al. Oral delivery and gastrointestinal absorption of soluble glucans stimulate increased resistance to infectious challenge. J. Pharmacol. Exp. Ther. 2005, 314, 1079-1086.
10. Saegusa, S., Totsuka, M., Kaminogawa, S., Hosoi, T., Candida albicans and Saccharomyces cerevisiae induce interleukin-8 production from intestinal epithelial-like Caco-2 cells in the presence of butyric acid. FEMS Immunol. Med. Microbiol. 2004, 41, 227-235.
11. Grinde, B., Hetland, G., Johnson, E., Effects on gene expression and viral load of a medicinal extract from Agaricus blazei in patients with chronic hepatitis C infection. Int. Immunopharmacol. 2006, 6, 1311-1314.
12. Olson, E. J., Standing, J. E., Griego-Harper, N., Hoffman, O. A., Limper, A. H., Fungal beta-glucan interacts with vitronectin and stimulates tumor necrosis factor alpha release from macrophages. Infect. Immun. 1996, 64, 3548-3554.
13. Sorimachi, K., Akimoto, K., Ikehara, Y., Inafuku, K. et al. Secretion of TNF-alpha, IL-8 and nitric oxide by macrophages activated with Agaricus blazei Murill fractions in vitro. Cell Struct. Funct. 2001, 26, 103-108.
14. Suzuki, I., Tanaka, H., Kinoshita, A., Oikawa, S. et al. Effect of orally administered beta-glucan on macrophage function in mice. Int. J. Immunopharmacol. 1990, 12, 675-684.
15. Ishibashi, K., Miura, N. N., Adachi, Y., Ohno, N., Yadomae, T., Relationship between solubility of grifolan, a fungal 1,3-beta-D-glucan, and production of tumor necrosis factor by macrophages in vitro. Biosci. Biotechnol. Biochem. 2001, 65, 1993-2000.
16. Lee, J. Y., Kim, J. Y., Lee, Y. G., Rhee, M. H. et al. Molecular mechanism of macrophage activation by Exopolysaccharides from liquid culture of Lentinus edodes. J. Microbiol. Biotechnol. 2008, 18, 355-364.
17. Kim, J. Y., Byeon, S. E., Lee, Y. G., Lee, J. Y. et al. Immunostimulatory activities of polysaccharides from liquid culture of pine-mushroom Tricholoma matsutake. J. Microbiol. Biotechnol. 2008, 18, 95-103.
18. Guerra Dore, C. M., Azevedo, T. C., de Souza, M. C., Rego, L. A. et al. Antiinflammatory, antioxidant and cytotoxic actions of beta-glucan-rich extract from Geastrum saccatum mushroom. Int. Immunopharmacol. 2007, 7, 1160-1169.
19. Brown, G. D., Gordon, S., Fungal beta-glucans and mammalian immunity. Immunity 2003, 19, 311-315.
20. Estrada, A., Yun, C. H., Van Kessel, A., Li, B. et al. Immunomodulatory activities of oat beta-glucan in vitro and in vivo. Microbiol. Immunol. 1997, 41, 991-998.
21. Graham, L. M., Tsoni, S. V., Willment, J. A., Williams, D. L. et al. Soluble Dectin-1 as a tool to detect beta-glucans. J. Immunol. Methods 2006, 314, 164-169.
22. Kang, P., Mechref, Y., Klouckova, I., Novotny, M. V., Solid-phase permethylation of glycans for mass spectrometric analysis. Rapid Commun. Mass Spectrom. 2005, 19, 3421-3428.
23. Shen, J., Ren, H., Tomiyama-Miyaji, C., Suga, Y. et al. Potentiation of intestinal immunity by micellary mushroom extracts. Biomed. Res. 2007, 28, 71-77.
24. Seguin, R., Mann, B. J., Keller, K., Chadee, K., The tumor necrosis factor alpha-stimulating region of galactose-inhibitable lectin of Entamoeba histolytica activates gamma interferon-primed macrophages for amebicidal activity mediated by nitric oxide. Infect. Immun. 1997, 65, 2522-2527.
25. Ramakers, J. D., Volman, J. J., Biorklund, M., Onning, G. et al. Fecal water from ileostomic patients consuming oat beta-glucan enhances immune responses in enterocytes. Mol. Nutr. Food Res. 2007, 51, 211-220.
26. Ding, A. H., Nathan, C. F., Stuehr, D. J., Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. J. Immunol. 1988, 141, 2407-2412.
27. Dentener, M. A., Greve, J. W., Maessen, J. G., Buurman, W. A., Role of tumour necrosis factor in the enhanced sensitivity of mice to endotoxin after exposure to lead. Immunopharmacol. Immunotoxicol. 1989, 11, 321-334.
28. Bernardshaw, S., Hetland, G., Ellertsen, L. K., Tryggestad, A. M., Johnson, E., An extract of the medicinal mushroom Agaricus blazei Murill differentially stimulates production of pro-inflammatory cytokines in human monocytes and human vein endothelial cells in vitro. Inflammation 2005, 29, 147-153.
29. Zekovic, D. B., Kwiatkowski, S., Vrvic, M. M., Jakovljevic, D., Moran, C. A., Natural and modified (13)-beta-D-glucans in health promotion and disease alleviation. Crit. Rev. Biotechnol. 2005, 25, 205-230.
30. Wessels, J. G. H., Developmental regulation of fungal cell wall formation. Ann. Rev. Phytopathol. 1994, 32, 413.
31. Calonje, M., Mendoza, C. G., Cabo, A. M., Novaes-Ledieu, M., Some significant differences in wall chemistry among four commercial Agaricus bisporus strains. Curr. Microbiol. 1995, 30, 111-115.
32. Bernardo, D., Mendoza, C. G., Calonje, M., Novaes-Ledieu, M., Chemical analysis of the lamella walls of Agaricus bisporus fruit bodies. Curr. Microbiol. 1999, 38, 364-367.
33. Brown, G. D., Dectin-1: a signalling non-TLR pattern-recognition receptor. Nat. Rev. Immunol. 2006, 6, 33-43.
34. Kubo, N., Myojin, Y., Shimamoto, F., Kashimoto, N. et al. Protective effects of a water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia and Agaricus blazei murill against X-irradiation in B6C3F1 mice: Increased small intestinal crypt survival and prolongation of average time to animal death. Int. J. Mol. Med. 2005, 15, 401-406.
35. Fadok, V. A., Bratton, D. L., Guthrie, L., Henson, P. M., Differential effects of apoptotic versus lysed cells on macrophage production of cytokines: role of proteases. J. Immunol. 2001, 166, 6847-6854.