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Volumn 10, Issue 5, 1996, Pages 345-363

Sodium valproate augments spontaneous neural tube defects and axial skeletal malformations into mouse fetuses

Author keywords

axial skeletal defects; craniofacial anomalies; exencephaly; sodium valproate; TO mouse

Indexed keywords

ANIMALIA;

EID: 0030250887     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/0890-6238(96)00081-0     Document Type: Article
Times cited : (26)

References (74)
  • 1
    • 0025888325 scopus 로고
    • Pregnancy and epilepsy
    • 1. Yerbi MS. Pregnancy and epilepsy, Epilepsia. 1991;32:S51-S55.
    • (1991) Epilepsia , vol.32
    • Yerbi, M.S.1
  • 2
    • 0021747828 scopus 로고
    • Teratogenicity of anticonvulsant drugs. I: Review of the literature
    • 2. Kelly TE. Teratogenicity of anticonvulsant drugs. I: Review of the literature. Am J Med Genet. 1984;19:413-34.
    • (1984) Am J Med Genet. , vol.19 , pp. 413-434
    • Kelly, T.E.1
  • 3
    • 0026087539 scopus 로고
    • Anticonvulsants in pregnancy
    • 3. Meadow R. Anticonvulsants in pregnancy. Arch Dis Child. 1991; 66:62-5.
    • (1991) Arch Dis Child. , vol.66 , pp. 62-65
    • Meadow, R.1
  • 4
    • 0026844611 scopus 로고
    • Major birth malformations and antiepileptic drugs
    • 4. Koch S, Loesche G, Jager Roman E, et al. Major birth malformations and antiepileptic drugs. Neurology. 1992;42(Suppl 5):83-8.
    • (1992) Neurology , vol.42 , Issue.SUPPL. 5 , pp. 83-88
    • Koch, S.1    Loesche, G.2    Jager Roman, E.3
  • 5
    • 0026842098 scopus 로고
    • Antiepileptic drugs and teratogenesis in two consecutive cohorts: Changes in prescription policy, paralleled by changes in pattern of malformations
    • 5. Lindhout D, Meinardi H, Meijer JWA, et al. Antiepileptic drugs and teratogenesis in two consecutive cohorts: Changes in prescription policy, paralleled by changes in pattern of malformations. Neurology Suppl. 1992;42:94-110.
    • (1992) Neurology Suppl. , vol.42 , pp. 94-110
    • Lindhout, D.1    Meinardi, H.2    Meijer, J.W.A.3
  • 6
    • 0011959233 scopus 로고
    • Congenital anomalies in the offspring of epileptic mothers
    • 6. Nakeno Y, Kaneko S. Congenital anomalies in the offspring of epileptic mothers. Cong Anom. 1992;32:309-21.
    • (1992) Cong Anom. , vol.32 , pp. 309-321
    • Nakeno, Y.1    Kaneko, S.2
  • 7
    • 0019965961 scopus 로고
    • Maternal valproic acid and congenital neural tube defects
    • 7. Robert E, Guibaud P. Maternal valproic acid and congenital neural tube defects. Lancet. 1982;2:937.
    • (1982) Lancet , vol.2 , pp. 937
    • Robert, E.1    Guibaud, P.2
  • 9
    • 0021910984 scopus 로고
    • Possible valproate teratogenicity
    • 9. Tein I, MacGregor DL. Possible valproate teratogenicity. Arch Neurol. 1985;42:291-93.
    • (1985) Arch Neurol. , vol.42 , pp. 291-293
    • Tein, I.1    MacGregor, D.L.2
  • 10
    • 0021069855 scopus 로고
    • Valproate and birth defects
    • 10. Robert E, Rosa F. Valproate and birth defects. Lancet. 1983;2: 1142.
    • (1983) Lancet , vol.2 , pp. 1142
    • Robert, E.1    Rosa, F.2
  • 12
    • 0022571613 scopus 로고
    • In utero exposure to valproate and neural tube defects
    • 12. Lindhout D, Schmidt D. In utero exposure to valproate and neural tube defects. Lancet 1986;1:1392-93.
    • (1986) Lancet , vol.1 , pp. 1392-1393
    • Lindhout, D.1    Schmidt, D.2
  • 15
    • 77957179936 scopus 로고
    • Pharmacologic evaluation of various metabolites and analogues of valproic acid: Teratogenic potencies in mice
    • 15. Nau H, Loscher W. Pharmacologic evaluation of various metabolites and analogues of valproic acid: teratogenic potencies in mice. Fundam Appl Toxicol. 1986;6:669-76.
    • (1986) Fundam Appl Toxicol. , vol.6 , pp. 669-676
    • Nau, H.1    Loscher, W.2
  • 16
    • 0023681232 scopus 로고
    • Strain differences in the teratogenicity induced by sodium valproate in cultured mouse embryos
    • 16. Naruse I, Collins MD, Scott WJ Jr. Strain differences in the teratogenicity induced by sodium valproate in cultured mouse embryos. Teratology. 1988;38:87-96.
    • (1988) Teratology , vol.38 , pp. 87-96
    • Naruse, I.1    Collins, M.D.2    Scott W.J., Jr.3
  • 18
    • 0028080907 scopus 로고
    • Exencephaly and axial skeletal malformations induced by maternal administration of sodium valproate in the MF1 mouse
    • 18. Padmanabhan R, Hameed MS. Exencephaly and axial skeletal malformations induced by maternal administration of sodium valproate in the MF1 mouse. J Craniofac Genet Dev Biol. 1994;14:192-205.
    • (1994) J Craniofac Genet Dev Biol. , vol.14 , pp. 192-205
    • Padmanabhan, R.1    Hameed, M.S.2
  • 19
    • 0026556607 scopus 로고
    • Valproic acid induced spina bifida: A mouse model
    • 19. Ehlers K, Sturje H, Merker HJ, Nau H. Valproic acid induced spina bifida: A mouse model. Teratology. 1992;45:145-54.
    • (1992) Teratology , vol.45 , pp. 145-154
    • Ehlers, K.1    Sturje, H.2    Merker, H.J.3    Nau, H.4
  • 20
    • 85024823834 scopus 로고
    • Neural tube defects in curly tail mice: Effects of administration of sodium valproate
    • 20. Padmanabhan R, Vaidhya HR. Neural tube defects in curly tail mice: Effects of administration of sodium valproate. Teratology. 1990;42:25A.
    • (1990) Teratology , vol.42
    • Padmanabhan, R.1    Vaidhya, H.R.2
  • 21
    • 0002324129 scopus 로고
    • Epidemiologic aspects of neural tube defects in the United States: Changing concepts and their importance for screening and prenatal diagnostic programs
    • Miejewski GJ, Porter IH, eds. New York: Academic Press
    • 21. Sever LE, Strassburg MA. Epidemiologic aspects of neural tube defects in the United States: Changing concepts and their importance for screening and prenatal diagnostic programs. In: Miejewski GJ, Porter IH, eds. Alpha-fetoprotein and congenital disorders. New York: Academic Press; 1985:243-62.
    • (1985) Alpha-Fetoprotein and Congenital Disorders , pp. 243-262
    • Sever, L.E.1    Strassburg, M.A.2
  • 23
    • 0020063425 scopus 로고
    • Etiologic heterogeneity of neural tube defects. I clues from epidemiology
    • 22. Khoury MJ, Erickson JD, James LM. Etiologic heterogeneity of neural tube defects. I Clues from epidemiology. Am J Epidemiol. 1982;115:538-48.
    • (1982) Am J Epidemiol. , vol.115 , pp. 538-548
    • Khoury, M.J.1    Erickson, J.D.2    James, L.M.3
  • 24
    • 0020282677 scopus 로고
    • Etiologic heterogeneity of neural tube defects. II. Clues from family studies
    • 23. Khoury MJ, Erickson JD, James LM. Etiologic heterogeneity of neural tube defects. II. Clues from family studies. Am J Hum Genet. 1982;34:980-87.
    • (1982) Am J Hum Genet. , vol.34 , pp. 980-987
    • Khoury, M.J.1    Erickson, J.D.2    James, L.M.3
  • 26
    • 0027175895 scopus 로고
    • Postulated mechanisms underlying the development of neural tube defects: Insight from in vitro and in vivo studies
    • 25. Sulik KK, Sadler TW. Postulated mechanisms underlying the development of neural tube defects: Insight from in vitro and in vivo studies. Ann NY Acad Sci. 1993;678:8-21.
    • (1993) Ann NY Acad Sci. , vol.678 , pp. 8-21
    • Sulik, K.K.1    Sadler, T.W.2
  • 27
    • 0026773188 scopus 로고
    • Interpretation of recurring weak associations obtained from epidemiological studies of suspected human teratogens
    • 26. Khoury MJ, James LM, Flanders WD, Erickson JD. Interpretation of recurring weak associations obtained from epidemiological studies of suspected human teratogens. Teratology. 1992;46:69-77.
    • (1992) Teratology , vol.46 , pp. 69-77
    • Khoury, M.J.1    James, L.M.2    Flanders, W.D.3    Erickson, J.D.4
  • 28
    • 0023691642 scopus 로고
    • Common hierarchies of susceptibility to the induction of neural tube defects in the mouse embryos by valproic acid and its 4-propyl-4 pentanoic acid metabolite
    • 27. Finnel RH, Bennet GD, Karras SB, Mohl VA . Common hierarchies of susceptibility to the induction of neural tube defects in the mouse embryos by valproic acid and its 4-propyl-4 pentanoic acid metabolite. Teratology. 1988;38:313-28.
    • (1988) Teratology , vol.38 , pp. 313-328
    • Finnel, R.H.1    Bennet, G.D.2    Karras, S.B.3    Mohl, V.A.4
  • 29
    • 0023681232 scopus 로고
    • Strain differences in the teratogenicity induced by sodium valproate in cultured mouse embryos
    • 28. Naruse I, Collins MD, Scott WJ. Strain differences in the teratogenicity induced by sodium valproate in cultured mouse embryos. Teratology. 1988;38:87-96.
    • (1988) Teratology , vol.38 , pp. 87-96
    • Naruse, I.1    Collins, M.D.2    Scott, W.J.3
  • 30
    • 0021032905 scopus 로고
    • Early morphological abnormalities in splotch mouse embryos and predisposition to gene- and retinoic acid-induced neural tube defects
    • 29. Dempsey EE, Trasler DG. Early morphological abnormalities in Splotch mouse embryos and predisposition to gene- and retinoic acid-induced neural tube defects. Teratology. 1983;28:461-72.
    • (1983) Teratology , vol.28 , pp. 461-472
    • Dempsey, E.E.1    Trasler, D.G.2
  • 31
    • 0018577147 scopus 로고
    • Stages of palate closure as an indication of liability to cleft palate
    • 30. Venkemans M, Fraser FC. Stages of palate closure as an indication of liability to cleft palate. Am J Med Genet. 1979;4:95-102.
    • (1979) Am J Med Genet. , vol.4 , pp. 95-102
    • Venkemans, M.1    Fraser, F.C.2
  • 32
    • 0022538284 scopus 로고
    • Effect of mitomycin C on the neural tube defects of the curly tail mouse
    • 31. Seller MJ, Perkins KJ. Effect of mitomycin C on the neural tube defects of the curly tail mouse. Teratology. 1986;33:305-9.
    • (1986) Teratology , vol.33 , pp. 305-309
    • Seller, M.J.1    Perkins, K.J.2
  • 33
    • 0023936633 scopus 로고
    • Histological comparison of the effects of the Splotch gene and retinoic acid on the closure of the mouse neural tube
    • 32. Kapron-Bras MC, Trasler DG. Histological comparison of the effects of the Splotch gene and retinoic acid on the closure of the mouse neural tube. Teratology. 1988;37:389-99.
    • (1988) Teratology , vol.37 , pp. 389-399
    • Kapron-Bras, M.C.1    Trasler, D.G.2
  • 34
    • 0025753068 scopus 로고
    • Studies of the effects of retinoic acid on anterior neural tube closure in mice genetically liable to exencephaly
    • 33. Tom C, Juriloff DM, Harris MJ. Studies of the effects of retinoic acid on anterior neural tube closure in mice genetically liable to exencephaly. Teratology. 1991;43:27-40.
    • (1991) Teratology , vol.43 , pp. 27-40
    • Tom, C.1    Juriloff, D.M.2    Harris, M.J.3
  • 35
    • 0027999641 scopus 로고
    • Effect of pretreatment with aspirin on alcohol-induced neural tube defects in the TO mouse fetuses
    • 34. Padmanabhan R, Wasfi IA, Craigmyle MBL. Effect of pretreatment with aspirin on alcohol-induced neural tube defects in the TO mouse fetuses. Drug Alcohol Depend. 1994;36:175-86.
    • (1994) Drug Alcohol Depend. , vol.36 , pp. 175-186
    • Padmanabhan, R.1    Wasfi, I.A.2    Craigmyle, M.B.L.3
  • 36
    • 0022350789 scopus 로고
    • A critical comparison of the freehand razor blade dissection method according to Wilson with an in situ sectioning method for rat fetuses
    • 35. Sterz H, Lehmann H. A critical comparison of the freehand razor blade dissection method according to Wilson with an in situ sectioning method for rat fetuses. Teratogenesis Carcinog Mutagen. 1985;5:347-54.
    • (1985) Teratogenesis Carcinog Mutagen , vol.5 , pp. 347-354
    • Sterz, H.1    Lehmann, H.2
  • 37
    • 0017061116 scopus 로고
    • Differential staining of cartilage and bone in fetal mouse skeleton by alcian blue and alizarin red-S
    • 36. Inouye M. Differential staining of cartilage and bone in fetal mouse skeleton by alcian blue and alizarin red-S. Cong Anom. 1976;16:171-3.
    • (1976) Cong Anom. , vol.16 , pp. 171-173
    • Inouye, M.1
  • 39
    • 0028912535 scopus 로고
    • Recent development in the etiology of neural tube defects
    • 38. Sellers MJ. Recent development in the etiology of neural tube defects. Clin Dysmorph. 1995;4:93-104.
    • (1995) Clin Dysmorph. , vol.4 , pp. 93-104
    • Sellers, M.J.1
  • 40
    • 0002571386 scopus 로고
    • Anencephaly
    • Vinken PJ, Bruyn GW, Klawans HL, eds, [50 revised series] Malformation. Amsterdam: Elsevier Sci Publ BV
    • 39. Lemire RJ. Anencephaly. In: Vinken PJ, Bruyn GW, Klawans HL, eds. Handbook of clinical neurology, vol 6 [50 revised series] Malformation. Amsterdam: Elsevier Sci Publ BV; 1987:71-95.
    • (1987) Handbook of Clinical Neurology , vol.6 , pp. 71-95
    • Lemire, R.J.1
  • 41
    • 0025063643 scopus 로고
    • Anencephaly: Its spectrum and relationship to neural tube defects
    • 40. Lemire RJ, Siebert JR. Anencephaly: Its spectrum and relationship to neural tube defects. J Craniofac Genet Dev Biol. 1990;10:163-74.
    • (1990) J Craniofac Genet Dev Biol. , vol.10 , pp. 163-174
    • Lemire, R.J.1    Siebert, J.R.2
  • 42
    • 0021674131 scopus 로고
    • Experimental induction of cranioschisis aperta and exencephaly after neural tube closure: A rat model
    • 41. Padmanabhan R. Experimental induction of cranioschisis aperta and exencephaly after neural tube closure: A rat model, J Neurol. Sci. 1984;66:235-43.
    • (1984) J Neurol. Sci. , vol.66 , pp. 235-243
    • Padmanabhan, R.1
  • 43
    • 0018970259 scopus 로고
    • Hypothesis: Overdistension of the neural tube may cause anomalies of nonneural organs
    • 42. Gardner WJ. Hypothesis: Overdistension of the neural tube may cause anomalies of nonneural organs. Teratology. 1980:22:229-38.
    • (1980) Teratology , vol.22 , pp. 229-238
    • Gardner, W.J.1
  • 44
    • 0025364510 scopus 로고
    • Mechanisms of neurulation: Traditional viewpoint and recent advances
    • 43. Schoenwolf GC, Smith JL. Mechanisms of neurulation: traditional viewpoint and recent advances. Development. 1990; 109:243-70.
    • (1990) Development , vol.109 , pp. 243-270
    • Schoenwolf, G.C.1    Smith, J.L.2
  • 45
    • 0023875525 scopus 로고
    • Light microscopic studies on the pathogenesis of exencephaly and cranioschisis induced in the rat after neural tube closure
    • 44. Padmanabhan R. Light microscopic studies on the pathogenesis of exencephaly and cranioschisis induced in the rat after neural tube closure. Teratology. 1988;37:29-36.
    • (1988) Teratology , vol.37 , pp. 29-36
    • Padmanabhan, R.1
  • 46
    • 0025886398 scopus 로고
    • Is exencephaly the forerunner of anencephaly? An experimental study on the effect of prolonged gestation on the exencephaly induced after neural tube closure in the rat
    • 45. Padmanabhan R. Is exencephaly the forerunner of anencephaly? An experimental study on the effect of prolonged gestation on the exencephaly induced after neural tube closure in the rat. Acta Anat. 1991;141:182-92.
    • (1991) Acta Anat. , vol.141 , pp. 182-192
    • Padmanabhan, R.1
  • 47
    • 0022376781 scopus 로고
    • Teratogenic valproic acid concentrations: Infusion by implanted minipumps vs. conventional injection regimen in the mouse
    • 46. Nau H. Teratogenic valproic acid concentrations: Infusion by implanted minipumps vs. conventional injection regimen in the mouse. Toxicol Appl Pharmacol. 1985;80:243-50.
    • (1985) Toxicol Appl Pharmacol. , vol.80 , pp. 243-250
    • Nau, H.1
  • 48
    • 77957179494 scopus 로고
    • Valproic acid teratogenicity in mice after various administration and phenobarbital pretreatment regimens: The parent drug and not one of the metabolites assayed is implicated as teratogen
    • 47. Nau H. Valproic acid teratogenicity in mice after various administration and phenobarbital pretreatment regimens: The parent drug and not one of the metabolites assayed is implicated as teratogen. Fundam Appl Toxicol 1986;6:662-8.
    • (1986) Fundam Appl Toxicol , vol.6 , pp. 662-668
    • Nau, H.1
  • 50
    • 0020613870 scopus 로고
    • Differential response of heterogeneous curly tail mouse embryos to vitamin A teratogenesis depending on maternal genotype
    • 49. Seller MJ, Perkins KJ, Adinolfi M. Differential response of heterogeneous curly tail mouse embryos to vitamin A teratogenesis depending on maternal genotype. Teratology. 1983;28:123-9.
    • (1983) Teratology , vol.28 , pp. 123-129
    • Seller, M.J.1    Perkins, K.J.2    Adinolfi, M.3
  • 51
    • 0013916792 scopus 로고
    • Polygenic control of teratogenicity of 5-fluorouracil in mice
    • 50. Dagg CP, Schleger G, Doerr A. Polygenic control of teratogenicity of 5-fluorouracil in mice. Genetics 1965;53:1101-17.
    • (1965) Genetics , vol.53 , pp. 1101-1117
    • Dagg, C.P.1    Schleger, G.2    Doerr, A.3
  • 52
    • 0021914763 scopus 로고
    • Spontaneous and retinoic acid-induced post-axial polydactyly
    • 51. Cusic AM, Dagg CP. Spontaneous and retinoic acid-induced post-axial polydactyly. Teratology. 1985;31:49-59.
    • (1985) Teratology , vol.31 , pp. 49-59
    • Cusic, A.M.1    Dagg, C.P.2
  • 53
    • 0025355724 scopus 로고
    • Teratogenic effects on the neuroepithelium of the CD-1 mouse embryo exposed in utero to sodium valproate
    • 52. Turner S, Sucheston ME, De Philip RM, Paulson RB. Teratogenic effects on the neuroepithelium of the CD-1 mouse embryo exposed in utero to sodium valproate. Teratology. 1990;41:421-42.
    • (1990) Teratology , vol.41 , pp. 421-442
    • Turner, S.1    Sucheston, M.E.2    De Philip, R.M.3    Paulson, R.B.4
  • 54
    • 0023922178 scopus 로고
    • Amniotic fluid cholinesterase of valproate-induced exencephaly in the mouse: An animal model for prenatal diagnosis of neural tube defects
    • 53. Elmazar MMA, Vogel R, Spielmann H. Amniotic fluid cholinesterase of valproate-induced exencephaly in the mouse: An animal model for prenatal diagnosis of neural tube defects. Arch Toxicol. 1988;61:501-3.
    • (1988) Arch Toxicol. , vol.61 , pp. 501-503
    • Elmazar, M.M.A.1    Vogel, R.2    Spielmann, H.3
  • 56
    • 0019955331 scopus 로고
    • Discordant expression of fetal hydantoin syndrome in heteropaternal dizygotic twins
    • 55. Phelan MC, Pellock JM, Nance WE. Discordant expression of fetal hydantoin syndrome in heteropaternal dizygotic twins. N Engl J Med. 1992;307:99-101.
    • (1992) N Engl J Med. , vol.307 , pp. 99-101
    • Phelan, M.C.1    Pellock, J.M.2    Nance, W.E.3
  • 57
    • 0027384764 scopus 로고
    • Preaxial ray reduction defects as part of valproic acid embryopathy
    • 56. Sharony R, Garber A, Viskochil D et al. Preaxial ray reduction defects as part of valproic acid embryopathy. Prenat Diagn. 1993; 13:909-18.
    • (1993) Prenat Diagn. , vol.13 , pp. 909-918
    • Sharony, R.1    Garber, A.2    Viskochil, D.3
  • 58
    • 0025296726 scopus 로고
    • Marked accumulation of valproic acid in embryonic neuroepithelium of the mouse during early organogenesis
    • 57. Denker L, Nau H, D'Argy R. Marked accumulation of valproic acid in embryonic neuroepithelium of the mouse during early organogenesis. Teratology. 1990;4:699-706.
    • (1990) Teratology , vol.4 , pp. 699-706
    • Denker, L.1    Nau, H.2    D'Argy, R.3
  • 59
    • 0028347278 scopus 로고
    • The teratogenic effects of valproic acid in human chondrogenesis in vitro
    • 58. Althouse AL, Hitt DC. The teratogenic effects of valproic acid in human chondrogenesis in vitro. Teratology. 1994;49:208-17.
    • (1994) Teratology , vol.49 , pp. 208-217
    • Althouse, A.L.1    Hitt, D.C.2
  • 60
    • 0027461863 scopus 로고
    • Intermittent pattern of neural tube closure in two strains of mice
    • 59. Golden JA , Chernoff, GF. Intermittent pattern of neural tube closure in two strains of mice. Teratology. 1993;47:73-80.
    • (1993) Teratology , vol.47 , pp. 73-80
    • Golden, J.A.1    Chernoff, G.F.2
  • 61
    • 0027493364 scopus 로고
    • Evidence for multi-site closure of neural tube in humans
    • 60. Van Allen MI, Kalousek DK, Chernoff GF, et al. Evidence for multi-site closure of neural tube in humans. Am J Med Genet. 1993;47:723-43.
    • (1993) Am J Med Genet. , vol.47 , pp. 723-743
    • Van Allen, M.I.1    Kalousek, D.K.2    Chernoff, G.F.3
  • 62
    • 0024539888 scopus 로고
    • Developmental study of neural tube closure in a mouse stock with a high incidence of exencephaly
    • 61. MacDonald KB, Juriloff DM, Harris MJ. Developmental study of neural tube closure in a mouse stock with a high incidence of exencephaly. Teratology. 1989; 39:195-213.
    • (1989) Teratology , vol.39 , pp. 195-213
    • MacDonald, K.B.1    Juriloff, D.M.2    Harris, M.J.3
  • 63
    • 0024422922 scopus 로고
    • Genetic analysis of the cause of exencephaly in the SELH/Bc mouse stock
    • 62. Juriloff DM, MacDonald KB, Harris MJ. Genetic analysis of the cause of exencephaly in the SELH/Bc mouse stock. Teratology. 1989;40:395-405.
    • (1989) Teratology , vol.40 , pp. 395-405
    • Juriloff, D.M.1    MacDonald, K.B.2    Harris, M.J.3
  • 64
    • 0026085654 scopus 로고
    • Development of anencephaly and its variants
    • 63. Muller F, O'Rahilly, R. Development of anencephaly and its variants. Am J Anat. 1991;190:193-218.
    • (1991) Am J Anat. , vol.190 , pp. 193-218
    • Muller, F.1    O'Rahilly, R.2
  • 65
    • 0026665226 scopus 로고
    • Experimental fetal alcohol syndrome: Proposed pathogenic basis for a variety of associated fetal and brain anomalies
    • 64. Kotch, LE, Sulik, KK. Experimental fetal alcohol syndrome: Proposed pathogenic basis for a variety of associated fetal and brain anomalies. Am J Med Genet. 1992;44:168-76.
    • (1992) Am J Med Genet. , vol.44 , pp. 168-176
    • Kotch, L.E.1    Sulik, K.K.2
  • 66
    • 0025977816 scopus 로고
    • Morphological differences elicited by two weak acids, retinoic and valproic, in rat embryos grown in vitro
    • 65. Seegmiller RE, Harris C, Luchtel DL , Juchau MR. Morphological differences elicited by two weak acids, retinoic and valproic, in rat embryos grown in vitro. Teratology. 1991;43:133-50.
    • (1991) Teratology , vol.43 , pp. 133-150
    • Seegmiller, R.E.1    Harris, C.2    Luchtel, D.L.3    Juchau, M.R.4
  • 67
    • 0018840748 scopus 로고
    • Morphogenesis of experimental encephalocele (cranioschisis occulta)
    • 66. Marin-Padilla M. Morphogenesis of experimental encephalocele (cranioschisis occulta). J Neurol Sci. 1980;46:83-99.
    • (1980) J Neurol Sci. , vol.46 , pp. 83-99
    • Marin-Padilla, M.1
  • 68
    • 0021419739 scopus 로고
    • Calvarial defects in human anencephaly
    • 67. Chaurasia BD. Calvarial defects in human anencephaly. Teratology. 1984;29:165-72.
    • (1984) Teratology , vol.29 , pp. 165-172
    • Chaurasia, B.D.1
  • 70
    • 0018728775 scopus 로고
    • Sensitivity patterns for the induction of homeotic shifts in a favorable strain of mice
    • 69. Russell LB. Sensitivity patterns for the induction of homeotic shifts in a favorable strain of mice. Teratology. 1979;20:115-26.
    • (1979) Teratology , vol.20 , pp. 115-126
    • Russell, L.B.1
  • 71
    • 0026465664 scopus 로고
    • Homeotic transformation in the mouse induced by overexpression of a human Hox 3.3 transgene
    • 70. Jegalian BG, De Robertis EM. Homeotic transformation in the mouse induced by overexpression of a human Hox 3.3 transgene. Cell. 1992;71:901-10.
    • (1992) Cell , vol.71 , pp. 901-910
    • Jegalian, B.G.1    De Robertis, E.M.2
  • 72
    • 0025941823 scopus 로고
    • Homeotic transformation of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid
    • 71. Kessel M, Gruss P. Homeotic transformation of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid. Cell. 1991;76:89-104.
    • (1991) Cell , vol.76 , pp. 89-104
    • Kessel, M.1    Gruss, P.2
  • 73
    • 0011984390 scopus 로고
    • Alteration in gene expression induced by valproic acid during murine neural tube closure
    • 72. An I, Bennet GD, Finnell RH. Alteration in gene expression induced by valproic acid during murine neural tube closure. Teratology. 1995;51:163.
    • (1995) Teratology , vol.51 , pp. 163
    • An, I.1    Bennet, G.D.2    Finnell, R.H.3
  • 74
    • 0023225405 scopus 로고
    • Valproic acid induced neural tube defects: Reduction by folinic acid in the mouse
    • 73. Trotz M, Wegner C R, Nau H. Valproic acid induced neural tube defects: Reduction by folinic acid in the mouse. Life Sci. 1987; 41:103-10.
    • (1987) Life Sci. , vol.41 , pp. 103-110
    • Trotz, M.1    Wegner, C.R.2    Nau, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.