Cytotoxicity of unsaturated metabolites of valproic acid and protection by vitamins G and E in glutathione-depleted rat hepatocytes

Toxicology

Volumn 112, Issue 1, 1996, Pages 69-85

  Jurima Romet, Malle ^a   Abbott, Frank S ^b   Tang, Wei ^b   Huang, Hide S ^a   Whitehouse, Larry W ^a  

^a Bureau of Drug Research   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Cytotoxicity; Glutathione; Metabolism; Rat hepatocytes; Valproic acid; Vitamin C; Vitamin E

Indexed keywords

2 PROPYL 2 PENTENOIC ACID; ALPHA TOCOPHEROL; ASCORBIC ACID; DRUG METABOLITE; LACTATE DEHYDROGENASE; VALPROIC ACID; VALPROIC ACID DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; DRUG METABOLISM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 0030221183     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0300-483X(96)03352-5     Document Type: Article

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