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Volumn 18, Issue 2, 1998, Pages 49-61

VPA-induced neural tube defects in mice. I. Altered metabolism of sulfur amino acids and glutathione

Author keywords

Glutathione; Homocysteine; Methionine; Mice; Neural tube defects; Teratogenicity; Valproic acid

Indexed keywords

CYSTEINE; FOLIC ACID; GLUTATHIONE; HOMOCYSTEINE; METHIONINE; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE; SERINE; SULFUR AMINO ACID; VALPROIC ACID;

EID: 0031668702     PISSN: 02703211     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-6866(1998)18:2<49::AID-TCM1>3.0.CO;2-D     Document Type: Article
Times cited : (29)

References (52)
  • 1
    • 0019965961 scopus 로고
    • Maternal valproic acid and congenital neural tube defects
    • Robert E, Guibaud P: Maternal valproic acid and congenital neural tube defects. Lancet 2:937, 1982.
    • (1982) Lancet , vol.2 , pp. 937
    • Robert, E.1    Guibaud, P.2
  • 3
    • 0022580946 scopus 로고
    • Transfer of valproic acid and its main active unsaturated metabolite to the gestational tissue: Correlation with Neural tube defect formation in the mouse
    • Nau H: Transfer of valproic acid and its main active unsaturated metabolite to the gestational tissue: Correlation with Neural tube defect formation in the mouse. Teratology 33:21-27, 1986.
    • (1986) Teratology , vol.33 , pp. 21-27
    • Nau, H.1
  • 4
    • 0026556607 scopus 로고
    • Valproic acid-induced Spina bifida: A mouse model
    • Ehlers K, Stuerje H, Merker HJ, Nau H: Valproic acid-induced Spina bifida: A mouse model. Teratology 45:145-154, 1992.
    • (1992) Teratology , vol.45 , pp. 145-154
    • Ehlers, K.1    Stuerje, H.2    Merker, H.J.3    Nau, H.4
  • 6
    • 0019476413 scopus 로고
    • Double-blind randomized controlled trial of folate treatment before conception to prevent recurrence of neural tube defects
    • Laurence KMNJ, Miller MH, Tennant GB, Campbell H: Double-blind randomized controlled trial of folate treatment before conception to prevent recurrence of neural tube defects. Brit Med J 282:1509-1511, 1981.
    • (1981) Brit Med J , vol.282 , pp. 1509-1511
    • Laurence, K.M.N.J.1    Miller, M.H.2    Tennant, G.B.3    Campbell, H.4
  • 7
    • 0023225405 scopus 로고
    • Valproic acid-induced neural tube defects: Reduction by folinic acid in the mouse
    • Troz M, Wegner C, Nau H: Valproic acid-induced neural tube defects: Reduction by folinic acid in the mouse. Life Sci 41:103-110, 1987.
    • (1987) Life Sci , vol.41 , pp. 103-110
    • Troz, M.1    Wegner, C.2    Nau, H.3
  • 8
    • 0025863475 scopus 로고
    • Prevention of neural tube defects: Result of the medical research council vitamin study
    • MRC Vitamin Study Research Group: Prevention of neural tube defects: Result of the medical research council vitamin study. Lancet 338: 131-137, 1991.
    • (1991) Lancet , vol.338 , pp. 131-137
  • 9
    • 0027080461 scopus 로고
    • Prevention of the first occurrence of neural tube defects by periconceptional vitamin supplementation
    • Czeizel AE, Dudus I: Prevention of the first occurrence of neural tube defects by periconceptional vitamin supplementation. N Engl J Med 327:1832-1835, 1992.
    • (1992) N Engl J Med , vol.327 , pp. 1832-1835
    • Czeizel, A.E.1    Dudus, I.2
  • 11
    • 0014525706 scopus 로고
    • 12-deficient rats
    • 12-deficient rats. J Nutr 98:139-146, 1969.
    • (1969) J Nutr , vol.98 , pp. 139-146
    • Woodward, J.C.1
  • 12
    • 0027744509 scopus 로고
    • In vitro effects of folate derivatives on valproate-induced neural tube defects in mouse and rat embryos
    • Hansen DK: In vitro effects of folate derivatives on valproate-induced neural tube defects in mouse and rat embryos. Toxic in Vitro 7:735-742, 1993.
    • (1993) Toxic in Vitro , vol.7 , pp. 735-742
    • Hansen, D.K.1
  • 13
    • 0027455468 scopus 로고
    • 12 alters the frequency of neural tube defects in Axd mutant mice
    • 12 alters the frequency of neural tube defects in Axd mutant mice. J Nutr 123:27-34, 1993.
    • (1993) J Nutr , vol.123 , pp. 27-34
    • Essien, F.B.1    Wannberg, S.L.2
  • 14
    • 0014897999 scopus 로고
    • Effect of diets devoid in one essential amino acid on pregnancy in rats maintained by ovarian steroids
    • Niiyama Y, Kishi K, Inoue G: Effect of diets devoid in one essential amino acid on pregnancy in rats maintained by ovarian steroids. J Nutr 100:1461-1470, 1970.
    • (1970) J Nutr , vol.100 , pp. 1461-1470
    • Niiyama, Y.1    Kishi, K.2    Inoue, G.3
  • 15
    • 0025000359 scopus 로고
    • Methionine and neural tube closure in cultured rat embryos: Morphological and biochemical analyses
    • Coelho CND, Klein NW: Methionine and neural tube closure in cultured rat embryos: Morphological and biochemical analyses. Teratology 42:437-451, 1990.
    • (1990) Teratology , vol.42 , pp. 437-451
    • Coelho, C.N.D.1    Klein, N.W.2
  • 16
    • 0030045586 scopus 로고    scopus 로고
    • Methionine reduces the valproic acid-induced spina bifida rate in mice without altering valproic acid kinetics
    • Ehlers K, Elmazar MMA, Nau H: Methionine reduces the valproic acid-induced spina bifida rate in mice without altering valproic acid kinetics. J Nutr 126:67-75, 1996.
    • (1996) J Nutr , vol.126 , pp. 67-75
    • Ehlers, K.1    Elmazar, M.M.A.2    Nau, H.3
  • 19
    • 0027930460 scopus 로고
    • Mechanism for the oxygen radical-mediated toxicity of various thiol-containing compounds in cultured mammalian cells
    • Held KD, Biaglow JE: Mechanism for the oxygen radical-mediated toxicity of various thiol-containing compounds in cultured mammalian cells. Radiat Res 139:15-23, 1994.
    • (1994) Radiat Res , vol.139 , pp. 15-23
    • Held, K.D.1    Biaglow, J.E.2
  • 20
    • 0028329986 scopus 로고
    • Lipid peroxidation and homocysteine induced toxicity
    • Jones BG, Rose FA, Tudball N: Lipid peroxidation and homocysteine induced toxicity. Atherosclerosis 105:165-170, 1994.
    • (1994) Atherosclerosis , vol.105 , pp. 165-170
    • Jones, B.G.1    Rose, F.A.2    Tudball, N.3
  • 22
    • 0027985632 scopus 로고
    • Status of glutathione during oxidant-induced oxidative stress in the preinaplantation mouse embryo
    • Gardiner CS, Reed DJ: Status of glutathione during oxidant-induced oxidative stress in the preinaplantation mouse embryo. Biol Reprod 51:1307-1314, 1994.
    • (1994) Biol Reprod , vol.51 , pp. 1307-1314
    • Gardiner, C.S.1    Reed, D.J.2
  • 24
    • 0025764492 scopus 로고
    • Free radical scavengers ameliorate the 2-cell block in mouse embryo culture
    • Legge M, Sellens MH: Free radical scavengers ameliorate the 2-cell block in mouse embryo culture. Hum Reprod 6:867-871, 1991.
    • (1991) Hum Reprod , vol.6 , pp. 867-871
    • Legge, M.1    Sellens, M.H.2
  • 26
    • 0021924421 scopus 로고
    • Valproic acid teratogenicity: Demonstration that the biochemical mechanism differs from that of valproate hepatotoxicity
    • Brown NA, Farmer PB, Coakley M: Valproic acid teratogenicity: Demonstration that the biochemical mechanism differs from that of valproate hepatotoxicity. Biochem Soc Trans 13:75-77, 1985.
    • (1985) Biochem Soc Trans , vol.13 , pp. 75-77
    • Brown, N.A.1    Farmer, P.B.2    Coakley, M.3
  • 28
    • 0027317471 scopus 로고
    • Modification of a high-performance liquid Chromatographic method for assay of homocysteine in human plasma
    • Cornwell PE, Morgan SL, Vaughn WH: Modification of a high-performance liquid Chromatographic method for assay of homocysteine in human plasma. J Chromatogr 617:136-139, 1993.
    • (1993) J Chromatogr , vol.617 , pp. 136-139
    • Cornwell, P.E.1    Morgan, S.L.2    Vaughn, W.H.3
  • 29
    • 0025848779 scopus 로고
    • Rapid high-performance liquid Chromatographic assay for total homocysteine levels in human serum
    • Ubbink JB, Hayward Vermaak WJ, Bissbort S: Rapid high-performance liquid Chromatographic assay for total homocysteine levels in human serum. J Chromatogr 565:441-446, 1991.
    • (1991) J Chromatogr , vol.565 , pp. 441-446
    • Ubbink, J.B.1    Hayward Vermaak, W.J.2    Bissbort, S.3
  • 30
    • 0023628783 scopus 로고
    • Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detection
    • Araki A, Sako Y: Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detection. J Chromatogr 422:43-52, 1987.
    • (1987) J Chromatogr , vol.422 , pp. 43-52
    • Araki, A.1    Sako, Y.2
  • 31
    • 0020972316 scopus 로고
    • o-phthaldialdehyde precolumn derivatization and reverse-phase high-performance liquid chromatography of polypeptide hydrolysates and physiological fluids
    • Jones BN, Gilligan JP: o-phthaldialdehyde precolumn derivatization and reverse-phase high-performance liquid chromatography of polypeptide hydrolysates and physiological fluids. J Chromatogr 266:471-482, 1983.
    • (1983) J Chromatogr , vol.266 , pp. 471-482
    • Jones, B.N.1    Gilligan, J.P.2
  • 32
    • 0022367025 scopus 로고
    • Determination of adenosine and S-adenosyl derivatives of sulfur amino acids in rat liver by high-performance liquid chromatography
    • Fell D, Benjamin LE, Steele RD: Determination of adenosine and S-adenosyl derivatives of sulfur amino acids in rat liver by high-performance liquid chromatography. J Chromatogr 345:150-156, 1985.
    • (1985) J Chromatogr , vol.345 , pp. 150-156
    • Fell, D.1    Benjamin, L.E.2    Steele, R.D.3
  • 33
    • 0021114730 scopus 로고
    • Fractionation and kinetic properties of rat liver and kidney methionine adenosyltransferase isozymes
    • Sullivan DM, Hoffman JL: Fractionation and kinetic properties of rat liver and kidney methionine adenosyltransferase isozymes. Biochemistry 22:1636-1641, 1983.
    • (1983) Biochemistry , vol.22 , pp. 1636-1641
    • Sullivan, D.M.1    Hoffman, J.L.2
  • 34
    • 0025362827 scopus 로고
    • Methionine metabolism in mammals
    • Finkelstein JD: Methionine metabolism in mammals. J Nutr Biochem 1:228-237, 1990.
    • (1990) J Nutr Biochem , vol.1 , pp. 228-237
    • Finkelstein, J.D.1
  • 35
    • 0000466478 scopus 로고
    • Activation of methionine for transmethylation
    • Cantoni GL: Activation of methionine for transmethylation. J Biol Chem 189:745-754, 1951.
    • (1951) J Biol Chem , vol.189 , pp. 745-754
    • Cantoni, G.L.1
  • 36
    • 0014197917 scopus 로고
    • Trans-sulfuration in mammals
    • Finkelstein JD, Mudd SH: Trans-sulfuration in mammals. J Biol Chem 242:873-880, 1967.
    • (1967) J Biol Chem , vol.242 , pp. 873-880
    • Finkelstein, J.D.1    Mudd, S.H.2
  • 38
    • 0026848306 scopus 로고
    • Alternation of embryonic folate metabolism by valproic acid during organogenesis: Implications for mechanism of teratogenesis
    • Wegner C. Nau H: Alternation of embryonic folate metabolism by valproic acid during organogenesis: Implications for mechanism of teratogenesis. Neurology 42:17-24, 1992.
    • (1992) Neurology , vol.42 , pp. 17-24
    • Wegner, C.1    Nau, H.2
  • 39
    • 0015228022 scopus 로고
    • Mammalian methylenetetrahydrofolate reductase; partial purification, properties, and inhibition by S-adenosylmethionine
    • Kutzbach C, Stokstad ELR: Mammalian methylenetetrahydrofolate reductase; partial purification, properties, and inhibition by S-adenosylmethionine. Biochim Biophys Acta 250:459-477, 1971.
    • (1971) Biochim Biophys Acta , vol.250 , pp. 459-477
    • Kutzbach, C.1    Stokstad, E.L.R.2
  • 40
    • 0021799251 scopus 로고
    • Studies on the mechanisms of neurulation in the chick: Interrelationship of contractile proteins, microfilaments, and the shape of neuroepithelial cells
    • Lee HY, Nagal RG: Studies on the mechanisms of neurulation in the chick: Interrelationship of contractile proteins, microfilaments, and the shape of neuroepithelial cells. J Exp Zool 235:205-215, 1985.
    • (1985) J Exp Zool , vol.235 , pp. 205-215
    • Lee, H.Y.1    Nagal, R.G.2
  • 41
    • 0031026635 scopus 로고    scopus 로고
    • Effects of methionine on the cytoplasmic distribution of actin and tubulin during neural tube closure in rat embryos
    • Moephuli SR, Klein NW, Baldwin MT, Krider HM: Effects of methionine on the cytoplasmic distribution of actin and tubulin during neural tube closure in rat embryos. Proc Natl Acad Sci USA 94:543-548, 1997.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 543-548
    • Moephuli, S.R.1    Klein, N.W.2    Baldwin, M.T.3    Krider, H.M.4
  • 43
    • 0020385002 scopus 로고
    • The production of free radicals during the autoxidation of cysteine and their effect on isolated rat hepatocytes
    • Saez G, Thornalley PJ, Hill HAO, Hems R, Bannister JV: The production of free radicals during the autoxidation of cysteine and their effect on isolated rat hepatocytes. Biochim Biophys Acta 719:24-31, 1982.
    • (1982) Biochim Biophys Acta , vol.719 , pp. 24-31
    • Saez, G.1    Thornalley, P.J.2    Hill, H.A.O.3    Hems, R.4    Bannister, J.V.5
  • 44
    • 0003180209 scopus 로고
    • The effect of thiols and disulfides on water uptake and extrusion by rat liver mitochondria
    • Neubert D, Lehninger AL: The effect of thiols and disulfides on water uptake and extrusion by rat liver mitochondria. J Biol Chem 237:952-958, 1962.
    • (1962) J Biol Chem , vol.237 , pp. 952-958
    • Neubert, D.1    Lehninger, A.L.2
  • 45
    • 0015504993 scopus 로고
    • Cysteine induced brain damage in infant and fetal rodents
    • Olney JW, Ho OL, Rhee V, Schainker B: Cysteine induced brain damage in infant and fetal rodents. Brain Res 45:309-313, 1972.
    • (1972) Brain Res , vol.45 , pp. 309-313
    • Olney, J.W.1    Ho, O.L.2    Rhee, V.3    Schainker, B.4
  • 46
    • 0018854098 scopus 로고
    • Amniotic fluid and maternal serum amino acid levels in malformations of fetal central nervous system
    • Kumar S, Foreman JR: Amniotic fluid and maternal serum amino acid levels in malformations of fetal central nervous system. Neurochem Res 5:453-458, 1980.
    • (1980) Neurochem Res , vol.5 , pp. 453-458
    • Kumar, S.1    Foreman, J.R.2
  • 47
    • 0025313835 scopus 로고
    • Early changes in hepatic redox homeostasis following treatment with a single dose of valproic acid
    • Cotariu D, Evans S, Zaidman JL, Marcus O: Early changes in hepatic redox homeostasis following treatment with a single dose of valproic acid. Biochem Pharmacol 40:589-593, 1990.
    • (1990) Biochem Pharmacol , vol.40 , pp. 589-593
    • Cotariu, D.1    Evans, S.2    Zaidman, J.L.3    Marcus, O.4
  • 49
    • 0021714062 scopus 로고
    • Early structural and functional changes in liver of rats treated with a single dose of valproic acid
    • Jezequel AM, Bonazzi P, Novelli G, Venturini C, Orlandi F: Early structural and functional changes in liver of rats treated with a single dose of valproic acid. Hepatology 4:1159-1166, 1984.
    • (1984) Hepatology , vol.4 , pp. 1159-1166
    • Jezequel, A.M.1    Bonazzi, P.2    Novelli, G.3    Venturini, C.4    Orlandi, F.5
  • 50
    • 0028860509 scopus 로고
    • Erythrocyte antioxidant enzyme activities in children with myelomeningocele
    • Graf WD, Pippenger CE, Shurtleff DB: Erythrocyte antioxidant enzyme activities in children with myelomeningocele. Dev Med Child Neurol 37:900-905, 1995.
    • (1995) Dev Med Child Neurol , vol.37 , pp. 900-905
    • Graf, W.D.1    Pippenger, C.E.2    Shurtleff, D.B.3
  • 51
    • 0029922411 scopus 로고    scopus 로고
    • Conjugation of glutathione with a toxic metabolite of valproic acid, (E)-2-propyl-2,4-pentadienoic acid, catalyzed by rat hepatic glutathione-S-transferases
    • Tang W, Borel AG, Abbott FS: Conjugation of glutathione with a toxic metabolite of valproic acid, (E)-2-propyl-2,4-pentadienoic acid, catalyzed by rat hepatic glutathione-S-transferases. Drug Metab Dispos 24:436-446, 1996.
    • (1996) Drug Metab Dispos , vol.24 , pp. 436-446
    • Tang, W.1    Borel, A.G.2    Abbott, F.S.3
  • 52
    • 0026625222 scopus 로고
    • Effects of valproate on xenobiotic biotransformation in rat liver. In vivo and in vitro experiments
    • Rogiers V, Callaerts A, Vercruysse A, Akrawi M, Shephard E, Phillips I: Effects of valproate on xenobiotic biotransformation in rat liver. In vivo and in vitro experiments. Pharm Weekbl Sci 14:127-131, 1992.
    • (1992) Pharm Weekbl Sci , vol.14 , pp. 127-131
    • Rogiers, V.1    Callaerts, A.2    Vercruysse, A.3    Akrawi, M.4    Shephard, E.5    Phillips, I.6


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