The effect of a single remote injection of statin-impregnated poly (lactic-co-glycolic acid) microspheres on osteogenesis around titanium implants in rat tibia

Biomaterials

Volumn 31, Issue 12, 2010, Pages 3327-3334

  Masuzaki, Tomohiro ^a   Ayukawa, Yasunori ^a   Moriyama, Yasuko ^a   Jinno, Yohei ^a   Atsuta, Ikiru ^a   Ogino, Yoichiro ^a   Koyano, Kiyoshi ^a  

^a Faculty of Dental Science   (Japan)

Author keywords

Bone formation; Dental implant; Drug delivery system; Fluvastatin; Microsphere; Poly (lactic co glycolic acid)

Indexed keywords

BONE FORMATION; DENTAL IMPLANTS; DRUG DELIVERY SYSTEM; FLUVASTATIN; POLY(LACTIC-CO-GLYCOLIC ACID);

ACIDS; BENDING STRENGTH; BIOCHEMISTRY; BONE; DRUG DELIVERY; MECHANICAL PROPERTIES; MICROSPHERES; POINT GROUPS; TITANIUM;

DENTAL PROSTHESES;

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CHOLESTEROL; CREATININE; FLUINDOSTATIN; MICROSPHERE; POLYGLACTIN; TITANIUM;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BONE DENSITY; BONE DEVELOPMENT; BONE METABOLISM; BONE STRENGTH; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG DELIVERY SYSTEM; FEMALE; FEMUR; HISTOPATHOLOGY; IN VITRO STUDY; MORPHOMETRICS; NONHUMAN; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE; SUSTAINED DRUG RELEASE; SUSTAINED RELEASE FORMULATION; TIBIA;

ANIMALS; FATTY ACIDS, MONOUNSATURATED; FEMALE; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INDOLES; LACTIC ACID; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; OSTEOGENESIS; POLYGLYCOLIC ACID; PROSTHESES AND IMPLANTS; RATS; RATS, SPRAGUE-DAWLEY; TIBIA; TITANIUM;

RATTUS;

EID: 76749106006     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.01.016     Document Type: Article

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