Locally delivered lovastatin nanoparticles enhance fracture healing in rats

Journal of Orthopaedic Research

Volumn 25, Issue 10, 2007, Pages 1351-1357

  Garrett, I R ^a,b   Gutierrez, G E ^a,b   Rossini, G ^b   Nyman, J ^c   McCluskey, B ^b   Flores, A ^b   Mundy, G R ^b  

^a OsteoScreen   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c The University of Texas at San Antonio   (United States)

Author keywords

Bone formation; HMG CoA reductase inhibitors; Lovastatin; Nanoparticles

Indexed keywords

MEVINOLIN; NANOBEAD; NANOPARTICLE; POLYGLACTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG RELEASE; FEMALE; FEMUR FRACTURE; FRACTURE HEALING; IN VITRO STUDY; LOW DRUG DOSE; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; OSSIFICATION; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY;

ANIMALS; ANIMALS, NEWBORN; ANTICHOLESTEREMIC AGENTS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; FEMALE; FEMORAL FRACTURES; FRACTURE HEALING; LOVASTATIN; MICE; MICE, INBRED ICR; NANOPARTICLES; ORGAN CULTURE TECHNIQUES; OSTEOGENESIS; RATS; RATS, SPRAGUE-DAWLEY; SKULL;

EID: 34948814564     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1002/jor.20391     Document Type: Article

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