T7 phage protein Gp2 inhibits the Escherichia coli RNA polymerase by antagonizing stable DNA strand separation near the transcription start site

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 5, 2010, Pages 2247-2252

  Cámara, Beatriz ^a   Liu, Minhao ^b   Reynolds, Jonathan ^a   Shadrin, Andrey ^c   Liu, Bing ^b   Kwok, King ^b   Simpson, Peter ^b   Weinzierl, Robert ^d   Severinov, Konstantin ^e,f   Cota, Ernesto ^b   Matthews, Steve ^b   Wigneshweraraj, Siva R ^a  

^a Centre for Molecular Microbiology and Infection   (United Kingdom)

^b Division of Molecular Biosciences   (United Kingdom)

^c SKRYABIN INSTITUTE OF BIOCHEMISTRY AND PHYSIOLOGY OF MICROORGANISMS   (Russian Federation)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e RUTGERS UNIVERSITY   (United States)

^f INSTITUTE OF MOLECULAR GENETICS   (Russian Federation)

Author keywords

Gene protein 2; Inhibitor; Promoter melting

Indexed keywords

ARGININE; BACTERIAL PROTEIN; PROTEIN GP2; RNA POLYMERASE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIOPHAGE T7; DNA STRAND; DNA STRAND BREAKAGE; ENZYME INHIBITION; ESCHERICHIA COLI; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STRUCTURE; TRANSCRIPTION INITIATION SITE;

BACTERIOPHAGE T7; BINDING SITES; DNA, BACTERIAL; DNA-DIRECTED RNA POLYMERASES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENES, BACTERIAL; GENES, VIRAL; MODELS, MOLECULAR; MULTIPROTEIN COMPLEXES; MUTATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROMOTER REGIONS, GENETIC; PROTEIN CONFORMATION; REPRESSOR PROTEINS; STATIC ELECTRICITY; TRANSCRIPTION INITIATION SITE;

ESCHERICHIA COLI;

EID: 76649129579     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0907908107     Document Type: Article

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