Weak mitochondrial targeting sequence determines tissue-specific subcellular localization of glutamine synthetase in liver and brain cells

Journal of Cell Science

Volumn 123, Issue 3, 2010, Pages 351-359

  Matthews, Gideon D ^a   Gur, Noa ^a   Koopman, Werner J H ^b   Pines, Ophry ^c   Vardimon, Lily ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Astrocytes; Glutamine synthetase; Hepatocytes; Mitochondrial membrane potential; Mitochondrial targeting signal; MTS; Uricotelic vertebrates

Indexed keywords

GLUTAMATE AMMONIA LIGASE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; ASTROCYTE; CELLULAR DISTRIBUTION; CHICKEN; CONTROLLED STUDY; CYTOPLASM; EMBRYO; ENZYME LOCALIZATION; ENZYME SPECIFICITY; LIVER CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; SIGNAL TRANSDUCTION; TISSUE SPECIFICITY;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; BRAIN; CELLS, CULTURED; CHICKENS; GLUTAMATE-AMMONIA LIGASE; IMMUNOPRECIPITATION; LIVER; MASS SPECTROMETRY; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, AMINO ACID;

VERTEBRATA;

EID: 76649117422     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.060749     Document Type: Article

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