NSAID drugs release from injectable microspheres produced by supercritical fluid emulsion extraction

Journal of Pharmaceutical Sciences

Volumn 99, Issue 3, 2010, Pages 1484-1499

  Della Porta, G ^a   Falco, N ^a   Reverchon, E ^a  

^a UNIVERSITY OF SALERNO   (Italy)

Author keywords

Emulsion; Microencapsulation; Poly(lactic glycolic) acid (PLGA or PLA); Polymeric drug delivery systems; Supercritical fluids

Indexed keywords

CARBON DIOXIDE; DICLOFENAC; MICROSPHERE; PIROXICAM; POLYGLACTIN; SOLVENT;

ARTICLE; CHEMICAL STRUCTURE; COMPARATIVE STUDY; DRUG RELEASE; EMULSION; EVAPORATION; MEMBRANE MICROPARTICLE; PARTICLE SIZE; REPRODUCTION; SUPERCRITICAL FLUID EXTRACTION; TECHNOLOGY;

EID: 76649091559     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21920     Document Type: Article

References (35)

1. Sam MT, Gayathri DS, Prasanth VV, Vinod B. 2008. NSAIDs as microspheres. Internet J Pharmacol 6:N.1.
2. Langer R. 1990. New methods of drug delivery. Science 249:1527-1533.
3. Verrijk R, Smolde IJ, Bosnie N, Begg AC. 1992. Reduction of systemic exposure and toxicity of cisplatin by encapsulation in poly(lactide-co- glycolide). Cancer Res 52:6653-6656.
4. Meinel L, Illi OE, Zapf J, Malfanti M, Merkle HP, Gander B. 2001. Stabilizing insulin-like grow factor in poly(lactide-co-glycolide) microspheres. J Control Release 70:193-202.
5. Walter E, Dreher D, Kok M, Thiele L, Kiama SG, Gehr P, Merkle HP. 2001. Hydrophylic poly(lactide-co-glycolide) microspheres for the delivery of DNA to human derived macrophages and dentritic cells. J Control Release 76:149-168.
6. Luten J, van Nostrum CF, De Smedt SC, Hennink WE. 2008. Biodegradable polymers as non-viral carriers for plasmid DNA delivery. J Control Release 126:97-110.
7. Berkland C, King M, Cox A, Kim K, Pack D. 2002. Precise control of PLG microsfere size provides enhanced control of drug release rate. J Control Release 82:137-147.
8. Berkland C, Kim K, Pack, D. 2003. PLG microsphere size controls drug release rate through several competing factors. Pharm Res 20-7:1055-1062.
9. Dunne M, Corrigan OI, Ramtolla Z. 2000. Influence of particle size and dissolution conditions on the degradation properties of polylactide-co-glycolide particles. Biomaterials 21:1659-1668.
10. O'Donnell PB, McGinity JW. 1997. Preparation of microspheres by the solvent evaporation technique. Adv Drug Deliv Rev 28:25-42.
11. Freitas S, Merkle HP, Gander B. 2005. Microencapsulation by solvent extraction/evaporation: Reviewing the state of the art of microsphere preparation process technology. J Control Release 102: 313-332.
12. Li M, Rouand O, Poncelet D. 2008. Microencapsulation by solvent evaporation: State of the art for process engineering approaches. Int J Pharm 363: 26-39.
13. Anderson JM, Shive MS. 1997. Biodegradation and biocompatibility of PLA and PLGA microspheres. Adv Drug Deliv Rev 28:5-24.
14. Faisant N, Akiki J, Siepmann F, Benoit JP, Siepmann J. 2006. Effects of the type of release medium on drug release from PLGA-based microparticles: Experiment and theory. Int J Pharm 314:189-197.
15. Klose D, Siepmann F, Elkharraz K, Krenzlin S, Siepmann J. 2006. How porosity and size affect the drug release mechanisms from PLGA-based microparticles. Int J Pharm 314:198-206.
16. Klose D, Siepmann F, Elkharraz K, Siepmann J. 2008. PLGA-based drug delivery systems: Importance of the type of drug and device geometry. Int J Pharm 354:95-103.
17. Castelli F, Conti B, Maccarrone DE, Conte U, Puglisi G. 1998. Comparative study of 'in vitro' release of anti-inflammatory drugs from polylactide-co-glycolide microspheres. Int J Pharm 176:85-98.
18. Bozdag S, Calis S, Kas HS, Ercan MT, Peksoy I, Hincal AA. 2001. In vitro evaluation and intraarticular administration of biodegradable microspheres containing naproxen sodium. J Microencapsul 18/4:443-456.
19. Della Porta G, De Vittori C, Reverchon E. 2005. Supercritical assisted atomization: A novel technology for micro-particles preparation of an asthma-controlling drug. AAPS Pharm Sci Tech 6/3:Article 52.
20. Yeo SD, Kiran E. 2005. Formation of polymer particles with supercritical fluids: A review. J Supercrit Fluids 34:287-308.
21. Della Porta G, Ercolino SF, Parente L, Reverchon E. 2006. Corticosteroids micro-particles produced by supercritical assisted atomization: Process optimization, product characterization and "in vitro" performance. J Pharm Sci 95/9:2062-2076.
22. Tandya A, Mammuccari R, Dehgani F, Foster NR. 2007. Dense gas processing of polymeric controlled release formulation. Int J Pharm 328:1-11.
23. Della Porta G, Reverchon E. 2007. Supercritical fluid-based technologies for particulate drug delivery. In: Ravi Kumar MNV, editor. Handbook of particulate drug delivery. New York: American Scientific Publication. pp. 35-59, ISBN 1-58883-079-9.
24. Wang Y, Pfeffer R, Dave R, Enick R. 2005. Polymer encapsulation of fine particles by a supercritical antisolvent process. AIChE J 51/2:440-455.
25. Lee LY, Wang CH, Smith KA. 2008. Supercritical antisolvent production of biodegradable micro- and nanoparticles for controlled delivery of paclitaxel. J Control Release 125:96-106.
26. Chattopadhyay P, Huff R, Shekunov BY. 2006. Drug encapsulation using supercritical fluid extraction of emulsions. J Pharm Sci 95:667-679.
27. Della Porta G, Reverchon E. 2008. Nanostructured microspheres produced by supercritical fluid extraction of emulsion. Biotechnol Bioeng 100/ 5:1020-1033.
28. Rosca ID, Watari F, Uo M. 2004. Microparticles formation and its mechanism in single and doule emulsion solvent evaporation. J Control Release 99:271-280.
29. Herrmann J, Bodmeier R. 1998. Biodegradable somatostatin acetate containing microspheres prepared by various aqueous and non-aqueous solvent evaporation methods. Eur J Pharm Biopharm 45: 75-82.
30. Mao S, Shi Y, Li L, Xu J, Schaper A, Kissel T. 2008. Effects of process and formulation parameters on characteristics and internal morphology of poly(D,L-lactide-co-glycolide) microspheres formed by the solvent evaporation method. Eur J Pharm Biopharm 68:214-223.
31. Reichl A, Daiminger U, Schmidt A, Davies M, Hoffmann U, Brinkmeier C, Reder C, Marquardt W. 1998. A non-recycle flow still for the experimental determination of vapor-liquid equilibria in reactive systems. Fluid Phase Equilibria 153:113-134.
32. Della Porta G, Volpe MC, Reverchon E. 2006. Supercritical cleaning of rollers for printing and packaging industry. J Supercrit Fluids 37:409-416.
33. Siepmann J, Gopferich A. 2001. Mathematical modelling of bioerodible, polymeric drug delivery system. Adv Drug Deliv Rev 48:229-247.
34. Lee PI. 1980. Diffusional release of a solute from a polymeric matrix-Approximate analytical solution. J Membr Sci 7:255-275.
35. Siepmann J, Elkharraz K, Siepmann F, Klose D. 2005. How autocatalysis accelerates drug release from PLGA-based microparticles: A quantitative treatment. Biomacromolecules 6/4:2312-2319.