Supercritical antisolvent production of biodegradable micro- and nanoparticles for controlled delivery of paclitaxel

Journal of Controlled Release

Volumn 125, Issue 2, 2008, Pages 96-106

  Lee, Lai Yeng ^a   Wang, Chi Hwa ^a,b   Smith, Kenneth A ^a,c  

^a SINGAPORE MIT ALLIANCE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

Biodegradable nanoparticles; Enhanced mixing; Paclitaxel; PLA; Supercritical antisolvent; Ultrasonication

Indexed keywords

BIODEGRADABLE POLYMERS; CARBON DIOXIDE; LACTIC ACID; MASS TRANSFER; PROBES; ULTRASONICS;

ANTISOLVENT PRODUCTION; ENHANCED MIXING; PACLITAXEL; SUBMICRON PARTICLES;

NANOPARTICLES;

CARBON DIOXIDE; NANOPARTICLE; PACLITAXEL; POLYLACTIC ACID; SOLVENT; TITANIUM;

ARTICLE; CONTROLLED DRUG RELEASE; DRUG DELIVERY SYSTEM; INTERMETHOD COMPARISON; NANOENCAPSULATION; PARTICLE SIZE; PRIORITY JOURNAL; SOLVENT EFFECT; SUPERCRITICAL FLUID; ULTRASOUND;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; DELAYED-ACTION PREPARATIONS; DIFFUSION; LACTIC ACID; MICROSCOPY, ELECTRON, SCANNING; MODELS, CHEMICAL; NANOPARTICLES; PACLITAXEL; PARTICLE SIZE; POLYMERS; SOLUBILITY; ULTRASONICS;

EID: 37349075381     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2007.10.002     Document Type: Article

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