PAP1 [poly(A) polymerase 1] homozygosity and hyperadenylation are major determinants of increased mRNA stability of CDR1 in azole-resistant clinical isolates of Candida albicans

Microbiology

Volumn 156, Issue 2, 2010, Pages 313-326

  Manoharlal, Raman ^a   Gorantala, Jyotsna ^a   Sharma, Monika ^a   Sanglard, Dominique ^b   Prasad, Rajendra ^a  

^a JAWAHARLAL NEHRU UNIVERSITY   (India)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ADENOSINE PHOSPHATE; BETA GALACTOSIDASE; MESSENGER RNA; POLYNUCLEOTIDE ADENYLYLTRANSFERASE; PROTEIN CDR1; PROTEIN PAP1; PYRROLE; RNA BINDING PROTEIN; UNCLASSIFIED DRUG; URIDINE PHOSPHATE;

3' UNTRANSLATED REGION; ALLELE; ARTICLE; CANDIDA ALBICANS; CHIMERA; CHROMOSOME 5; CONSENSUS SEQUENCE; CONTROLLED STUDY; FUNGUS ISOLATION; GENE CONSTRUCT; GENE DELETION; GENE LOCUS; GENE MAPPING; GENETIC HETEROGENEITY; HETEROLOGOUS EXPRESSION; HETEROZYGOSITY LOSS; HOMOZYGOSITY; MOLECULAR MECHANICS; NONHUMAN; POLYADENYLATION; PRIORITY JOURNAL; RNA STABILITY;

3' UNTRANSLATED REGIONS; ANTIFUNGAL AGENTS; AZOLES; BETA-GALACTOSIDASE; CANDIDA ALBICANS; CANDIDIASIS, ORAL; CLONING, MOLECULAR; DRUG RESISTANCE, FUNGAL; FUNGAL PROTEINS; HOMOZYGOTE; HUMANS; LOSS OF HETEROZYGOSITY; MEMBRANE TRANSPORT PROTEINS; MICROBIAL SENSITIVITY TESTS; POLY A; POLYMORPHISM, GENETIC; POLYNUCLEOTIDE ADENYLYLTRANSFERASE; RNA STABILITY; RNA, FUNGAL; RNA, MESSENGER;

CANDIDA ALBICANS;

EID: 76449116487     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/mic.0.035154-0     Document Type: Article

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