Serum repressing efflux pump CDR1 in Candida albicans

BMC Molecular Biology

Volumn 7, Issue , 2006, Pages

  Yang, Yun Liang ^a   Lin, Yi Hsuan ^b   Tsao, Ming Yang ^b   Chen, Chia Geun ^b   Shih, Hsin I ^a   Fan, Jen Chung ^b   Wang, Jang Shiun ^b,c   Lo, Hsiu Jung ^b  

^a NATIONAL CHIAO TUNG UNIVERSITY   (Taiwan)

^b NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^c NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ANTIFUNGAL AGENT; MESSENGER RNA; MICONAZOLE; N ACETYLGLUCOSAMINE; PROTEIN CDR1; RENILLA LUCIFERIN 2 MONOOXYGENASE; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ARTICLE; CANDIDA ALBICANS; CANDIDIASIS; CONTROLLED STUDY; CULTURE MEDIUM; DRUG SENSITIVITY; FUNGAL CELL; IN VITRO STUDY; IN VIVO STUDY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PREDICTION; PROTEIN EXPRESSION; PROTEIN TRANSPORT; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SERUM; TREATMENT OUTCOME; WILD TYPE;

ANIMALS; ANTIFUNGAL AGENTS; CANDIDA ALBICANS; CATTLE; CULTURE MEDIA; DNA-BINDING PROTEINS; DRUG RESISTANCE, FUNGAL; FLUCONAZOLE; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; LUCIFERASES, RENILLA; MEMBRANE TRANSPORT PROTEINS; MICROBIAL SENSITIVITY TESTS; POLYMERASE CHAIN REACTION; PROMOTER REGIONS, GENETIC; SERUM; TRANSCRIPTION FACTORS;

CANDIDA ALBICANS; RENILLA LUCIFERASE;

EID: 33747370049     PISSN: 14712199     EISSN: 14712199     Source Type: Journal    
DOI: 10.1186/1471-2199-7-22     Document Type: Article

References (16)

1. Pfaller MA, Jones RN, Doern GV, Sader HS, Messer SA, Houston A, Coffman S, Hollis RJ: Bloodstream infections due to Candida species: SENTRY antimicrobial surveillance program in North America and Latin America, 1997-1998. Antimicrob Agents Chemother 2000, 44:747-751.
2. Yang YL, Li SY, Cheng HH, Lo HJ: Susceptibilities to amphotericin B and fluconazolle of Candida species in TSARY 2002. Diagn Microbiol Infect Dis 2005, 51:179-183.
3. Karababa M, Coste AT, Rognon B, Bille J, Sanglard D: Comparison of gene expression profiles of Condida albicans azole-resistant clinical isolates and laboratory strains exposed to drugs inducing multidrug transporters. Antimicrob Agents Chemother 2004, 48:3064-3079.
4. Sanglard D, Ischer F, Monod M, Bille J: Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitors. Antimicrob Agents Chemother 1996, 40:2300-2305.
5. Yang YL, Lo HJ: Mechanisms of antifungal agent resistance. J Microbiol Immunol Infect 2001, 34:79-86.
6. Murad AM, d'Enfert C, Gaillardin C, Tournu H, Tekaia F, Talibi D, Marechal D, Marchais V, Cottin J, Brown AJ: Transcript profiling in Candido albicans reveals new cellular functions for the transcriptional repressors CaTup1, CaMig1 and CaNrg1. Mol Microbiol 2001, 42:981-993.
7. Chen CG, Yang YL, Shih HI, Su CL, Lo HJ: CaNdt80 is involved in drug resistance in Candida albicans by regulating CDR1. Antimicrob Agents Chemother 2004, 48:4505-4512.
8. Coste AT, Karababa M, Ischer F, Bille J, Sanglard D: TAC 1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candido albicans ABC transporters CDR1 and CDR2. Eukaryot Cell 2004, 3:1639-1652.
9. Zhanel GG, Saunders DG, Hoban DJ, Karlowsky JA: Influence of human serum an antifungal pharmacodynamics with Candida albicans. Antimicrob Agents Chemother 2001, 45:2018-2022.
10. White TC, Marr KA, Bowden RA: Clinical, cellular, and molecular factors that contribute to antifungal drug resistance. Clin Microbiol Rev 1998, 11:382-402.
11. Puri N, Krishnamurthy S, Habib S, Hasnain SE, Goswami SK, Prasad R: CDR1, a multidrug resistance gene from Candida albicans, contains multiple regulatory domains in its promoter and the distal AP-1 element mediates its induction by miconazole. FEMS Microbiol Lett 1999, 180:213-219.
12. Castilla R, Passeron S, Cantore ML: N-acetyl-D-glucosamine induces germination in Candida albicans through a mechanism sensitive to inhibitors of cAMP-dependent protein kinase. Cell Signal 1998, 10:713-719.
13. Mattia E, Carruba G, Angiolella L, Cassone A: Induction of germ tube formation by N-acetyl-D-glucosamine in Candido albicans: uptake of inducer and germinative response. J Bacteriol 1982, 152:555-562.
14. Clinical and Laboratory Standards Institute (formly NCCLS): Reference method for broth dilution antifungal susceptibility testing of yeasts; approved standard. M27A, Wayne, PA 1997.
15. Wilson RB, Davis D, Mitchell AP: Rapid hypothesis testing with Candida albicans through gene disruption with short homology regions. J Bacteriol 1999, 181:1868-1874.
16. Kofron M, Demel T, Xanthos J, Lohr J, Sun B, Sive H, Osada S, Wright C, Wylie C, Heasman J: Mesoderm induction in Xenopus is a zygotic event regulated by maternal VegT via TGFbeta. growth factors. Development 1999, 126:5759-5770.