-
1
-
-
0034614490
-
Signaling-2000 and beyond
-
Hunter T: Signaling-2000 and beyond. Cell 2000;100:113-127.
-
(2000)
Cell
, vol.100
, pp. 113-127
-
-
Hunter, T.1
-
2
-
-
0037032835
-
The protein kinase complement of the human genome
-
Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S: The protein kinase complement of the human genome. Science 2002;298:1912-1934.
-
(2002)
Science
, vol.298
, pp. 1912-1934
-
-
Manning, G.1
Whyte, D.B.2
Martinez, R.3
Hunter, T.4
Sudarsanam, S.5
-
3
-
-
57749188299
-
Targeting cancer with small molecule kinase inhibitors
-
Zhang J, Yang PL, Gray NS: Targeting cancer with small molecule kinase inhibitors. Nat Rev Cancer 2009;9:28-39.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 28-39
-
-
Zhang, J.1
Yang, P.L.2
Gray, N.S.3
-
4
-
-
67649726156
-
Protein kinase inhibitors: Contributions from structure to clinical compounds
-
Johnson LN: Protein kinase inhibitors: contributions from structure to clinical compounds. Q Rev Biophys 2009;42:1-40.
-
(2009)
Q Rev Biophys
, vol.42
, pp. 1-40
-
-
Johnson, L.N.1
-
5
-
-
0036527429
-
Protein kinases-the major drug targets of the twenty-first century?
-
Cohen P: Protein kinases-the major drug targets of the twenty-first century? Nat Rev Drug Discov 2002;1:309-315.
-
(2002)
Nat Rev Drug Discov
, vol.1
, pp. 309-315
-
-
Cohen, P.1
-
6
-
-
40549123675
-
Current in vitro kinase assay technologies: The quest for a universal format
-
Jia Y, Quinn CM, Kwak S, Talanian RV: Current in vitro kinase assay technologies: the quest for a universal format. Curr Drug Discov Technol 2008;5:59-69.
-
(2008)
Curr Drug Discov Technol
, vol.5
, pp. 59-69
-
-
Jia, Y.1
Quinn, C.M.2
Kwak, S.3
Talanian, R.V.4
-
7
-
-
45949106612
-
The challenge of selecting protein kinase assays for lead discovery optimization
-
Ma H, Deacon S, Horiuchi K: The challenge of selecting protein kinase assays for lead discovery optimization. Expert Opin Drug Discov 2008;3:607-621.
-
(2008)
Expert Opin Drug Discov
, vol.3
, pp. 607-621
-
-
Ma, H.1
Deacon, S.2
Horiuchi, K.3
-
8
-
-
0033003760
-
A simple statistical parameter for use in evaluation and validation of high throughput screening assays
-
Zhang JH, Chung TD, Oldenburg KR: A simple statistical parameter for use in evaluation and validation of high throughput screening assays. J Biomol Screen 1999;4:67-73.
-
(1999)
J Biomol Screen
, vol.4
, pp. 67-73
-
-
Zhang, J.H.1
Chung, T.D.2
Oldenburg, K.R.3
-
9
-
-
0037518278
-
Structural basis for peptide binding in protein kinase A. Role of glutamic acid 203 and tyrosine 204 in the peptide-positioning loop
-
Moore MJ, Adams JA, Taylor SS: Structural basis for peptide binding in protein kinase A. Role of glutamic acid 203 and tyrosine 204 in the peptide-positioning loop. J Biol Chem 2003;278:10613-10618.
-
(2003)
J Biol Chem
, vol.278
, pp. 10613-10618
-
-
Moore, M.J.1
Adams, J.A.2
Taylor, S.S.3
-
10
-
-
0030010603
-
Examination of an active-site electrostatic node in the cAMP-dependent protein kinase catalytic subunit
-
Grant BD, Tsigelny I, Adams JA, Taylor SS: Examination of an active-site electrostatic node in the cAMP-dependent protein kinase catalytic subunit. Protein Sci 1996;5:1316-1324. (Pubitemid 26239439)
-
(1996)
Protein Science
, vol.5
, Issue.7
, pp. 1316-1324
-
-
Grant, B.D.1
Tsigelny, I.2
Adams, J.A.3
Taylor, S.S.4
-
11
-
-
0017638132
-
Role of multiple basic residues in determining the substrate specificity of cyclic AMP-dependent protein kinase
-
Kemp BE, Graves DJ, Benjamini E, Krebs EG: Role of multiple basic residues in determining the substrate specificity of cyclic AMP-dependent protein kinase. J Biol Chem 1977;252:4888-4894.
-
(1977)
J Biol Chem
, vol.252
, pp. 4888-4894
-
-
Kemp, B.E.1
Graves, D.J.2
Benjamini, E.3
Krebs, E.G.4
-
13
-
-
0028866845
-
Different susceptibility of protein kinases to staurosporine inhibition. Kinetic studies and molecular bases for the resistance of protein kinase CK2
-
Meggio F, Donella Deana A, Ruzzene M, Brunati AM, Cesaro L, Guerra B, et al.: Different susceptibility of protein kinases to staurosporine inhibition. Kinetic studies and molecular bases for the resistance of protein kinase CK2. Eur J Biochem 1995;234:317-322.
-
(1995)
Eur J Biochem
, vol.234
, pp. 317-322
-
-
Meggio, F.1
Donella Deana, A.2
Ruzzene, M.3
Brunati, A.M.4
Cesaro, L.5
Guerra, B.6
-
14
-
-
0026009187
-
Utilization of the inhibitor protein of adenosine cyclic monophosphate-dependent protein kinase, and peptides derived from it, as tools to study adenosine cyclic monophosphate-mediated cellular processes
-
Walsh DA, Glass DB: Utilization of the inhibitor protein of adenosine cyclic monophosphate-dependent protein kinase, and peptides derived from it, as tools to study adenosine cyclic monophosphate-mediated cellular processes. Meth Enzymol 1991;201:304-316.
-
(1991)
Meth Enzymol
, vol.201
, pp. 304-316
-
-
Walsh, D.A.1
Glass, D.B.2
-
15
-
-
14444279192
-
Identification of a novel inhibitor of mitogen-activated protein kinase kinase
-
Favata MF, Horiuchi KY, Manos EJ, Daulerio AJ, Stradley DA, Feeser WS, et al.: Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J Biol Chem 1998;273:18623-18632.
-
(1998)
J Biol Chem
, vol.273
, pp. 18623-18632
-
-
Favata, M.F.1
Horiuchi, K.Y.2
Manos, E.J.3
Daulerio, A.J.4
Stradley, D.A.5
Feeser, W.S.6
-
16
-
-
34249886323
-
Development of a Transcreener kinase assay for protein kinase A and demonstration of concordance of data with a filter-binding assay format
-
Huss KL, Blonigen PE, Campbell RM: Development of a Transcreener kinase assay for protein kinase A and demonstration of concordance of data with a filter-binding assay format. J Biomol Screen 2007;12:578-584.
-
(2007)
J Biomol Screen
, vol.12
, pp. 578-584
-
-
Huss, K.L.1
Blonigen, P.E.2
Campbell, R.M.3
-
17
-
-
33144487285
-
Transcreener: Screening enzymes involved in covalent regulation
-
Lowery RG, Kleman-Leyer K: Transcreener: screening enzymes involved in covalent regulation. Expert Opin Ther Targets 2006;10:179-190.
-
(2006)
Expert Opin Ther Targets
, vol.10
, pp. 179-190
-
-
Lowery, R.G.1
Kleman-Leyer, K.2
-
18
-
-
67349233597
-
Evaluating the utility of the HTRF Transcreener ADP assay technology: A comparison with the standard HTRF assay technology
-
Hong L, Quinn CM, Jia Y: Evaluating the utility of the HTRF Transcreener ADP assay technology: a comparison with the standard HTRF assay technology. Anal Biochem 2009;391:31-38.
-
(2009)
Anal Biochem
, vol.391
, pp. 31-38
-
-
Hong, L.1
Quinn, C.M.2
Jia, Y.3
-
19
-
-
0034992432
-
Assaying activity of individual protein kinases in crude tissue or cellular extracts
-
Goueli SA, Hsiao K, Goueli BS: Assaying activity of individual protein kinases in crude tissue or cellular extracts. Meth Enzymol 2001;333:16-27.
-
(2001)
Meth Enzymol
, vol.333
, pp. 16-27
-
-
Goueli, S.A.1
Hsiao, K.2
Goueli, B.S.3
-
20
-
-
0033773937
-
Fluorescence polarization and anisotropy in high throughput screening: Perspectives and primer
-
Owicki JC: Fluorescence polarization and anisotropy in high throughput screening: perspectives and primer. J Biomol Screen 2000;5:297-306.
-
(2000)
J Biomol Screen
, vol.5
, pp. 297-306
-
-
Owicki, J.C.1
-
22
-
-
0037620455
-
A homogeneous, nonradioactive high-throughput fluorogenic protein kinase assay
-
Kupcho K, Somberg R, Bulleit B, Goueli SA: A homogeneous, nonradioactive high-throughput fluorogenic protein kinase assay. Anal Biochem 2003;317:210-217.
-
(2003)
Anal Biochem
, vol.317
, pp. 210-217
-
-
Kupcho, K.1
Somberg, R.2
Bulleit, B.3
Goueli, S.A.4
-
23
-
-
33744912806
-
A generic, homogenous method for measuring kinase and inhibitor activity via adenosine 5?-diphosphate accumulation
-
Charter NW, Kauffman L, Singh R, Eglen RM: A generic, homogenous method for measuring kinase and inhibitor activity via adenosine 5?-diphosphate accumulation. J Biomol Screen 2006;11:390-399.
-
(2006)
J Biomol Screen
, vol.11
, pp. 390-399
-
-
Charter, N.W.1
Kauffman, L.2
Singh, R.3
Eglen, R.M.4
-
24
-
-
0035860103
-
Homogeneous time resolved fluorescence resonance energy transfer using rare earth cryptates as a tool for probing molecular interactions in biology
-
Bazin H, Preaudat M, Trinquet E, Mathis G: Homogeneous time resolved fluorescence resonance energy transfer using rare earth cryptates as a tool for probing molecular interactions in biology. Spectrochim Acta A Mol Biomol Spectrosc 2001;57:2197-2211.
-
(2001)
Spectrochim Acta A Mol Biomol Spectrosc
, vol.57
, pp. 2197-2211
-
-
Bazin, H.1
Preaudat, M.2
Trinquet, E.3
Mathis, G.4
-
25
-
-
33748154598
-
Assay concordance between SPA and TR-FRET in high-throughput screening
-
von Ahsen O, Schmidt A, Klotz M, Parczyk K: Assay concordance between SPA and TR-FRET in high-throughput screening. J Biomol Screen 2006;11:606-616.
-
(2006)
J Biomol Screen
, vol.11
, pp. 606-616
-
-
Von Ahsen, O.1
Schmidt, A.2
Klotz, M.3
Parczyk, K.4
-
26
-
-
0013223828
-
A FRET-based assay platform for ultra-high density drug screening of protein kinases and phosphatases
-
Rodems SM, Hamman BD, Lin C, Zhao J, Shah S, Heidary D, et al.: A FRET-based assay platform for ultra-high density drug screening of protein kinases and phosphatases. Assay Drug Dev Technol 2002;1:9-19.
-
(2002)
Assay Drug Dev Technol
, vol.1
, pp. 9-19
-
-
Rodems, S.M.1
Hamman, B.D.2
Lin, C.3
Zhao, J.4
Shah, S.5
Heidary, D.6
-
27
-
-
85130288518
-
A homogenous, luminescent, high-throughput, versatile assay for a wide range of kinases
-
(Minor LK, ed.), Taylor & Francis Group, LLC. CRC, Boca Raton, FL
-
Goueli SA, Hsiao K, Bulleit B: A homogenous, luminescent, high-throughput, versatile assay for a wide range of kinases. In: Handbook of Assay Development in Drug Discovery (Minor LK, ed.), pp. 99-114. Taylor & Francis Group, LLC. CRC, Boca Raton, FL, 2006.
-
(2006)
Handbook of Assay Development in Drug Discovery
, pp. 99-114
-
-
Goueli, S.A.1
Hsiao, K.2
Bulleit, B.3
-
28
-
-
2442457423
-
High-throughput screening with quantitation of ATP consumption: A universal non-radioisotope, homogeneous assay for protein kinase
-
Koresawa M, Okabe T: High-throughput screening with quantitation of ATP consumption: a universal non-radioisotope, homogeneous assay for protein kinase. Assay Drug Dev Technol 2004;2:153-160.
-
(2004)
Assay Drug Dev Technol
, vol.2
, pp. 153-160
-
-
Koresawa, M.1
Okabe, T.2
-
29
-
-
34147216138
-
A high throughput luminescent assay for glycogen synthase kinase-3beta inhibitors
-
Baki A, Bielik A, Molnar L, Szendrei G, Keseru GM: A high throughput luminescent assay for glycogen synthase kinase-3beta inhibitors. Assay Drug Dev Technol 2007;5:75-83.
-
(2007)
Assay Drug Dev Technol
, vol.5
, pp. 75-83
-
-
Baki, A.1
Bielik, A.2
Molnar, L.3
Szendrei, G.4
Keseru, G.M.5
-
30
-
-
64349092077
-
A basis for reduced chemical library inhibition of firefl y luciferase obtained from directed evolution
-
Auld DS, Zhang Y-Q, Southall NT, Rai G, Landsman M, Maclure J, et al.: A basis for reduced chemical library inhibition of firefl y luciferase obtained from directed evolution. J Med Chem 2009;52:1450-1458.
-
(2009)
J Med Chem
, vol.52
, pp. 1450-1458
-
-
Auld, D.S.1
Zhang, Y.-Q.2
Southall, N.T.3
Rai, G.4
Landsman, M.5
MacLure, J.6
-
31
-
-
76449108493
-
Comparison of bioluminescent kinase assays using substrate depletion and product formation
-
Tanega C, Shen M, Mott BT, Thomas CJ, MacArthur R, Inglese J, Auld DS: Comparison of bioluminescent kinase assays using substrate depletion and product formation. Assay Drug Dev Technol 2009;7:XX-XX
-
(2009)
Assay Drug Dev Technol
, vol.7
-
-
Tanega, C.1
Shen, M.2
Mott, B.T.3
Thomas, C.J.4
MacArthur, R.5
Inglese, J.6
Auld, D.S.7
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