Deletion of the distal COOH-terminus of the A 2B adenosine receptor switches internalization to an arrestin- and clathrin-independent pathway and inhibits recycling

British Journal of Pharmacology

Volumn 159, Issue 3, 2010, Pages 518-533

  Mundell, S J ^a   Matharu, A L ^a   Nisar, S ^a   Palmer, T M ^b   Benovic, J L ^c   Kelly, E ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

A 2B adenosine receptor; Arrestin; COOH terminus deletion; Internalization

Indexed keywords

ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A2B RECEPTOR; CLATHRIN; DYNAMIN; EPIDERMAL GROWTH FACTOR RECEPTOR PATHWAY SUBSTRATE 15; GLUTAMINE; LEUCINE; PHENYLALANINE; PROTEIN ZO1; RETINA S ANTIGEN; SERINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL COMPARTMENTALIZATION; CELL CYCLE; CELL MIGRATION; CELL SURFACE; CHO CELL; CONTROLLED STUDY; DRUG EXPOSURE; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE DELETION; IMMUNOFLUORESCENCE MICROSCOPY; INTERNALIZATION; MUTANT; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN MOTIF; RAT; WILD TYPE;

AMINO ACID MOTIFS; ANIMALS; ARRESTIN; CELL MEMBRANE; CHO CELLS; CLATHRIN; CRICETINAE; CRICETULUS; DYNAMINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GLUTAMINE; LEUCINE; MICROSCOPY, FLUORESCENCE; PHENYLALANINE; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RATS; RECEPTOR, ADENOSINE A2B; RECEPTORS, PURINERGIC P1; SEQUENCE DELETION;

EID: 76449087001     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2009.00598.x     Document Type: Article

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