Bile acid reflux contributes to development of esophageal adenocarcinoma via activation of phosphatidylinositol-specific phospholipase Cγ2 and NADPH oxidase NOX5-S

Cancer Research

Volumn 70, Issue 3, 2010, Pages 1247-1255

  Hong, Jie ^a   Behar, Jose ^a   Wands, Jack ^a   Resnick, Murray ^a   Wang, Li Juan ^a   DeLellis, Ronald A ^a   Lambeth, David ^b   Cao, Weibiao ^a  

^a BROWN UNIVERSITY   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; BILE ACID; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 1; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE PHOSPHODIESTERASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SMALL INTERFERING RNA; TAURODEOXYCHOLIC ACID;

ARTICLE; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ESOPHAGEAL ADENOCARCINOMA; GASTROESOPHAGEAL REFLUX; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

ADENOCARCINOMA; BILE ACIDS AND SALTS; BILE REFLUX; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; CHOLAGOGUES AND CHOLERETICS; ENZYME ACTIVATION; ESOPHAGEAL NEOPLASMS; ESTRENES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYDROGEN PEROXIDE; ISOENZYMES; MEMBRANE PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 1; NADPH OXIDASE; PHOSPHODIESTERASE INHIBITORS; PHOSPHOLIPASE C GAMMA; PYRROLIDINONES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TAURODEOXYCHOLIC ACID;

EID: 76349095785     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-2774     Document Type: Article

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