메뉴 건너뛰기




Volumn 75, Issue 4, 2004, Pages 705-713

The receptor tyrosine kinase MerTK activates phospholipase C γ2 during recognition of apoptotic thymocytes by murine macrophages

Author keywords

Apoptosis; Inbred strains; Mice; Phagocytosis; Protein kinases phosphatases; Signal transduction

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 2,5 PYRROLIDINEDIONE; ANTIBODY; ISOPROTEIN; PHOSPHATIDYLINOSITOL SPECIFIC PHOSPHOLIPASE; PHOSPHATIDYLSERINE; PHOSPHATIDYLSERINE RECEPTOR; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA2; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

EID: 1642506285     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0903439     Document Type: Article
Times cited : (71)

References (71)
  • 1
    • 0035209395 scopus 로고    scopus 로고
    • The phagocytosis of apoptotic cells
    • Fadok, V. A., Chimini, G. (2001) The phagocytosis of apoptotic cells. Semin. Immunol. 13, 365-372.
    • (2001) Semin. Immunol. , vol.13 , pp. 365-372
    • Fadok, V.A.1    Chimini, G.2
  • 2
    • 0027477318 scopus 로고
    • Nucleosome: A major immunogen for pathogenic autoantibody-inducing T cells of lupus
    • Mohan, C., Adams, S., Stanik, V., Datta, S. K. (1993) Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus. J. Exp. Med. 177, 1367-1381.
    • (1993) J. Exp. Med. , vol.177 , pp. 1367-1381
    • Mohan, C.1    Adams, S.2    Stanik, V.3    Datta, S.K.4
  • 3
    • 0028284788 scopus 로고
    • The central role of chromatin in autoimmune responses to histones and DNA in systemic lupus erythematosus
    • Burlingame, R. W., Boey, M. L., Starkebaum, G., Rubin, R. L. (1994) The central role of chromatin in autoimmune responses to histones and DNA in systemic lupus erythematosus. J. Clin. Invest. 94, 184-192.
    • (1994) J. Clin. Invest. , vol.94 , pp. 184-192
    • Burlingame, R.W.1    Boey, M.L.2    Starkebaum, G.3    Rubin, R.L.4
  • 6
    • 0033485401 scopus 로고    scopus 로고
    • Transcriptional and translational regulation of inflammatory mediator production by endogenous TGF-β in macrophages that have ingested apoptotic cells
    • McDonald, P. P., Fadok, V. A., Bratton, D., Henson, P. M. (1999) Transcriptional and translational regulation of inflammatory mediator production by endogenous TGF-β in macrophages that have ingested apoptotic cells. J. Immunol. 163, 6164-6172.
    • (1999) J. Immunol. , vol.163 , pp. 6164-6172
    • McDonald, P.P.1    Fadok, V.A.2    Bratton, D.3    Henson, P.M.4
  • 9
    • 0021857103 scopus 로고
    • Causes of mortality in patients with the adult respiratory distress syndrome
    • Montgomery, A. B., Stager, M. A., Carrico, C. J., Hudson, L. D. (1985) Causes of mortality in patients with the adult respiratory distress syndrome. Am. Rev. Respir. Dis. 132, 485-489.
    • (1985) Am. Rev. Respir. Dis. , vol.132 , pp. 485-489
    • Montgomery, A.B.1    Stager, M.A.2    Carrico, C.J.3    Hudson, L.D.4
  • 11
    • 0033012376 scopus 로고    scopus 로고
    • Regulation of phosphatidylserine exposure and phagocytosis of apoptotic T lymphocytes
    • Verhoven, B., Krahling, S., Schlegel, R. A., Williamson, P. (1999) Regulation of phosphatidylserine exposure and phagocytosis of apoptotic T lymphocytes. Cell Death Differ. 6, 262-270.
    • (1999) Cell Death Differ. , vol.6 , pp. 262-270
    • Verhoven, B.1    Krahling, S.2    Schlegel, R.A.3    Williamson, P.4
  • 13
    • 0027989808 scopus 로고
    • Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis
    • Koopman, G., Reutelingsperger, C. P., Kuijten, G. A., Keehnen, R. M., Pals, S. T., van Oers, M. H. (1994) Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood 84, 1415-1420.
    • (1994) Blood , vol.84 , pp. 1415-1420
    • Koopman, G.1    Reutelingsperger, C.P.2    Kuijten, G.A.3    Keehnen, R.M.4    Pals, S.T.5    Van Oers, M.H.6
  • 14
    • 0028942106 scopus 로고
    • Human neutrophils lose their surface FcγRIII and acquire Annexin V binding sites during apoptosis in vitro
    • Homburg, C. H., de Haas, M., von dem Borne, A. E., Verhoeven, A. J., Reutelingsperger, C. P., Roos, D. (1995) Human neutrophils lose their surface FcγRIII and acquire Annexin V binding sites during apoptosis in vitro. Blood 85, 532-540.
    • (1995) Blood , vol.85 , pp. 532-540
    • Homburg, C.H.1    De Haas, M.2    Von Dem Borne, A.E.3    Verhoeven, A.J.4    Reutelingsperger, C.P.5    Roos, D.6
  • 15
    • 0028800947 scopus 로고
    • Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl
    • Martin, S. J., Reutelingsperger, C. P., McGahon, A. J., Rader, J. A., van Schie, R. C., LaFace, D. M., Green, D. R. (1995) Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl. J. Exp. Med. 182, 1545-1556.
    • (1995) J. Exp. Med. , vol.182 , pp. 1545-1556
    • Martin, S.J.1    Reutelingsperger, C.P.2    McGahon, A.J.3    Rader, J.A.4    Van Schie, R.C.5    LaFace, D.M.6    Green, D.R.7
  • 16
    • 0037184049 scopus 로고    scopus 로고
    • Activation of protein kinase C β II by the stereo-specific phosphatidylserine receptor is required for phagocytosis of apoptotic thymocytes by resident murine tissue macrophages
    • Todt, J. C., Hu, B., Punturieri, A., Sonstein, J., Polak, T., Curtis, J. L. (2002) Activation of protein kinase C β II by the stereo-specific phosphatidylserine receptor is required for phagocytosis of apoptotic thymocytes by resident murine tissue macrophages. J. Biol. Chem. 277, 35906-35914.
    • (2002) J. Biol. Chem. , vol.277 , pp. 35906-35914
    • Todt, J.C.1    Hu, B.2    Punturieri, A.3    Sonstein, J.4    Polak, T.5    Curtis, J.L.6
  • 18
    • 0035854442 scopus 로고    scopus 로고
    • Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family
    • Lu, Q., Lemke, G. (2001) Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family. Science 293, 306-311.
    • (2001) Science , vol.293 , pp. 306-311
    • Lu, Q.1    Lemke, G.2
  • 19
    • 0033950998 scopus 로고    scopus 로고
    • CD14-dependent clearance of apoptotic cells: Relevance to the immune system
    • Gregory, C. D. (2000) CD14-dependent clearance of apoptotic cells: relevance to the immune system. Curr. Opin. Immunol. 12, 27-34.
    • (2000) Curr. Opin. Immunol. , vol.12 , pp. 27-34
    • Gregory, C.D.1
  • 21
    • 0035846941 scopus 로고    scopus 로고
    • Loss of phospholipid asymmetry and surface exposure of phosphatidylserine is required for phagocytosis of apoptotic cells by macrophages and fibroblasts
    • Fadok, V. A., de Cathelineau, A., Daleke, D. L., Henson, P. M., Bratton, D. L. (2001) Loss of phospholipid asymmetry and surface exposure of phosphatidylserine is required for phagocytosis of apoptotic cells by macrophages and fibroblasts. J. Biol. Chem. 276, 1071-1077.
    • (2001) J. Biol. Chem. , vol.276 , pp. 1071-1077
    • Fadok, V.A.1    De Cathelineau, A.2    Daleke, D.L.3    Henson, P.M.4    Bratton, D.L.5
  • 22
    • 0035128074 scopus 로고    scopus 로고
    • Requirement for Rho GTPases and PI 3-kinases during apoptotic cell phagocytosis by macrophages
    • Leverrier, Y., Ridley, A. J. (2001) Requirement for Rho GTPases and PI 3-kinases during apoptotic cell phagocytosis by macrophages. Curr. Biol. 11, 195-199.
    • (2001) Curr. Biol. , vol.11 , pp. 195-199
    • Leverrier, Y.1    Ridley, A.J.2
  • 23
    • 0036587746 scopus 로고    scopus 로고
    • Recognition and phagocytosis of apoptotic T cells by resident murine macrophages requires multiple signal transduction events
    • Hu, B., Punturieri, A., Todt, J., Sonstein, J., Polak, T., Curtis, J. L. (2002) Recognition and phagocytosis of apoptotic T cells by resident murine macrophages requires multiple signal transduction events. J. Leukoc. Biol. 71, 881-889.
    • (2002) J. Leukoc. Biol. , vol.71 , pp. 881-889
    • Hu, B.1    Punturieri, A.2    Todt, J.3    Sonstein, J.4    Polak, T.5    Curtis, J.L.6
  • 24
    • 0033555931 scopus 로고    scopus 로고
    • A requirement for phosphatidylinositol 3-kinase in pseudopod extension
    • Cox, D., Tseng, C. C., Bjekic, G., Greenberg, S. (1999) A requirement for phosphatidylinositol 3-kinase in pseudopod extension. J. Biol. Chem. 274, 1240-1247.
    • (1999) J. Biol. Chem. , vol.274 , pp. 1240-1247
    • Cox, D.1    Tseng, C.C.2    Bjekic, G.3    Greenberg, S.4
  • 25
    • 0033779101 scopus 로고    scopus 로고
    • Structure, function, and control of phosphoinositide-specific phospholipase C
    • Rebecchi, M. J., Pentyala, S. N. (2000) Structure, function, and control of phosphoinositide-specific phospholipase C. Physiol. Rev. 80, 1291-1335.
    • (2000) Physiol. Rev. , vol.80 , pp. 1291-1335
    • Rebecchi, M.J.1    Pentyala, S.N.2
  • 26
    • 0034927336 scopus 로고    scopus 로고
    • Regulation of phosphoinositide-specific phospholipase C
    • Rhee, S. G. (2001) Regulation of phosphoinositide-specific phospholipase C. Annu. Rev. Biochem. 70, 281-312.
    • (2001) Annu. Rev. Biochem. , vol.70 , pp. 281-312
    • Rhee, S.G.1
  • 27
    • 0025605968 scopus 로고
    • Increase of the catalytic activity of phospholipase C-γ 1 by tyrosine phosphorylation
    • Nishibe, S., Wahl, M. I., Hernandez-Sotomayor, S. M., Tonks, N. K., Rhee, S. G., Carpenter, G. (1990) Increase of the catalytic activity of phospholipase C-γ 1 by tyrosine phosphorylation. Science 250, 1253-1256.
    • (1990) Science , vol.250 , pp. 1253-1256
    • Nishibe, S.1    Wahl, M.I.2    Hernandez-Sotomayor, S.M.3    Tonks, N.K.4    Rhee, S.G.5    Carpenter, G.6
  • 28
    • 0029662025 scopus 로고    scopus 로고
    • The α2β1 integrin is a necessary co-receptor for collagen-induced activation of Syk and the subsequent phosphorylation of phospholipase Cγ2 in platelets
    • Keely, P. J., Parise, L. V. (1996) The α2β1 integrin is a necessary co-receptor for collagen-induced activation of Syk and the subsequent phosphorylation of phospholipase Cγ2 in platelets. J. Biol. Chem. 271, 26668-26676.
    • (1996) J. Biol. Chem. , vol.271 , pp. 26668-26676
    • Keely, P.J.1    Parise, L.V.2
  • 29
    • 0029935857 scopus 로고    scopus 로고
    • Stimulation of Fc(α) receptors induces tyrosine phosphorylation of phospholipase C-γ(1), phosphatidylinositol phosphate hydrolysis, and Ca2+ mobilization in rat and human mesangial cells
    • Gomez-Guerrero, C., Duque, N., Egido, J. (1996) Stimulation of Fc(α) receptors induces tyrosine phosphorylation of phospholipase C-γ(1), phosphatidylinositol phosphate hydrolysis, and Ca2+ mobilization in rat and human mesangial cells. J. Immunol. 156, 4369-4376.
    • (1996) J. Immunol. , vol.156 , pp. 4369-4376
    • Gomez-Guerrero, C.1    Duque, N.2    Egido, J.3
  • 30
    • 0028971813 scopus 로고
    • Phosphoinositide-specific phospholipase C and mitogenic signaling
    • Noh, D. Y., Shin, S. H., Rhee, S. G. (1995) Phosphoinositide-specific phospholipase C and mitogenic signaling. Biochim. Biophys. Acta 1242, 99-113.
    • (1995) Biochim. Biophys. Acta , vol.1242 , pp. 99-113
    • Noh, D.Y.1    Shin, S.H.2    Rhee, S.G.3
  • 31
    • 0028979712 scopus 로고
    • Ligation of the α2-macroglobulin signalling receptor on macrophages induces protein phosphorylation and an increase in cytosolic pH
    • Misra, U. K., Gawdi, G., Pizzo, S. V. (1995) Ligation of the α2-macroglobulin signalling receptor on macrophages induces protein phosphorylation and an increase in cytosolic pH. Biochem. J. 309, 151-158.
    • (1995) Biochem. J. , vol.309 , pp. 151-158
    • Misra, U.K.1    Gawdi, G.2    Pizzo, S.V.3
  • 32
    • 0036142839 scopus 로고    scopus 로고
    • Regulation of phospholipase C-γ 2 via phosphatidylinositol 3-kinase in macrophages
    • Hiller, G., Sundler, R. (2002) Regulation of phospholipase C-γ 2 via phosphatidylinositol 3-kinase in macrophages. Cell. Signal. 14, 169-173.
    • (2002) Cell. Signal. , vol.14 , pp. 169-173
    • Hiller, G.1    Sundler, R.2
  • 33
    • 0037114147 scopus 로고    scopus 로고
    • Phospholipase C γ2 is essential for specific functions of Fc εR and Fc γR
    • Wen, R., Jou, S. T., Chen, Y., Hoffmeyer, A., Wang, D. (2002) Phospholipase C γ2 is essential for specific functions of Fc εR and Fc γR. J. Immunol. 169, 6743-6752.
    • (2002) J. Immunol. , vol.169 , pp. 6743-6752
    • Wen, R.1    Jou, S.T.2    Chen, Y.3    Hoffmeyer, A.4    Wang, D.5
  • 34
    • 2642709170 scopus 로고    scopus 로고
    • Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growth
    • Xia, P., Aiello, L. P., Ishii, H., Jiang, Z. Y., Park, D. J., Robinson, G. S., Takagi, H., Newsome, W. P., Jirousek, M. R., King, G. L. (1996) Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growth. J. Clin. Invest. 98, 2018-2026.
    • (1996) J. Clin. Invest. , vol.98 , pp. 2018-2026
    • Xia, P.1    Aiello, L.P.2    Ishii, H.3    Jiang, Z.Y.4    Park, D.J.5    Robinson, G.S.6    Takagi, H.7    Newsome, W.P.8    Jirousek, M.R.9    King, G.L.10
  • 35
    • 0036510590 scopus 로고    scopus 로고
    • Interferon-γ-induced epithelial ICAM-1 expression and monocyte adhesion. Involvement of protein kinase C-dependent c-Src tyrosine kinase activation pathway
    • Chang, Y. J., Holtzman, M. J., Chen, C. C. (2002) Interferon-γ -induced epithelial ICAM-1 expression and monocyte adhesion. Involvement of protein kinase C-dependent c-Src tyrosine kinase activation pathway. J. Biol. Chem. 277, 7118-7126.
    • (2002) J. Biol. Chem. , vol.277 , pp. 7118-7126
    • Chang, Y.J.1    Holtzman, M.J.2    Chen, C.C.3
  • 36
    • 0034283944 scopus 로고    scopus 로고
    • TNF-α-induced cyclooxygenase-2 expression in human lung epithelial cells: Involvement of the phospholipase C γ2, protein kinase C α, tyrosine kinase, NF-κB-inducing kinase, and I-κB kinase 1/2 pathway
    • Chen, C. C., Sun, Y. T., Chen, J. J., Chiu, K. T. (2000) TNF-α-induced cyclooxygenase-2 expression in human lung epithelial cells: involvement of the phospholipase C γ2, protein kinase C α, tyrosine kinase, NF-κB-inducing kinase, and I-κB kinase 1/2 pathway. J. Immunol. 165, 2719-2728.
    • (2000) J. Immunol. , vol.165 , pp. 2719-2728
    • Chen, C.C.1    Sun, Y.T.2    Chen, J.J.3    Chiu, K.T.4
  • 37
    • 0028875948 scopus 로고
    • Mitogenic signals and transforming potential of Nyk, a newly identified neural cell adhesion molecule-related receptor tyrosine kinase
    • Ling, L., Kung, H. J. (1995) Mitogenic signals and transforming potential of Nyk, a newly identified neural cell adhesion molecule-related receptor tyrosine kinase. Mol. Cell. Biol. 15, 6582-6592.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6582-6592
    • Ling, L.1    Kung, H.J.2
  • 38
    • 0034663992 scopus 로고    scopus 로고
    • Deficient in vitro and in vivo phagocytosis of apoptotic T cells by resident murine alveolar macrophages
    • Hu, B., Sonstein, J., Christensen, P. J., Punturieri, A., Curtis, J. L. (2000) Deficient in vitro and in vivo phagocytosis of apoptotic T cells by resident murine alveolar macrophages. J. Immunol. 165, 2124-2133.
    • (2000) J. Immunol. , vol.165 , pp. 2124-2133
    • Hu, B.1    Sonstein, J.2    Christensen, P.J.3    Punturieri, A.4    Curtis, J.L.5
  • 39
    • 0025201019 scopus 로고
    • Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils
    • Bleasdale, J. E., Thakur, N. R., Gremban, R. S., Bundy, G. L., Fitzpatrick, F. A., Smith, R. J., Bunting, S. (1990) Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils. J. Pharmacol. Exp. Ther. 255, 756-768.
    • (1990) J. Pharmacol. Exp. Ther. , vol.255 , pp. 756-768
    • Bleasdale, J.E.1    Thakur, N.R.2    Gremban, R.S.3    Bundy, G.L.4    Fitzpatrick, F.A.5    Smith, R.J.6    Bunting, S.7
  • 40
    • 0026742177 scopus 로고
    • Selective inhibition of phosphatidylinositol phospholipase C by cytotoxic ether lipid analogues
    • Powis, G., Seewald, M. J., Gratas, C., Melder, D., Riebow, J., Modest, E. J. (1992) Selective inhibition of phosphatidylinositol phospholipase C by cytotoxic ether lipid analogues. Cancer Res. 52, 2835-2840.
    • (1992) Cancer Res. , vol.52 , pp. 2835-2840
    • Powis, G.1    Seewald, M.J.2    Gratas, C.3    Melder, D.4    Riebow, J.5    Modest, E.J.6
  • 41
    • 0004252445 scopus 로고
    • Englewood Cliffs, NJ, Prentice-Hall
    • Zar, J. H. (1974) Biostatistical Analysis. Englewood Cliffs, NJ, Prentice-Hall.
    • (1974) Biostatistical Analysis
    • Zar, J.H.1
  • 42
    • 0033025909 scopus 로고    scopus 로고
    • An assay for the quantitative measurement of in vitro phagocytosis of early apoptotic thymocytes by murine resident peritoneal macrophages
    • Licht, R., Jacobs, C. W., Tax, W. J., Berden, J. H. (1999) An assay for the quantitative measurement of in vitro phagocytosis of early apoptotic thymocytes by murine resident peritoneal macrophages. J. Immunol. Methods 223, 237-248.
    • (1999) J. Immunol. Methods , vol.223 , pp. 237-248
    • Licht, R.1    Jacobs, C.W.2    Tax, W.J.3    Berden, J.H.4
  • 44
    • 0029744682 scopus 로고    scopus 로고
    • Identification of the major autophosphorylation sites of Nyk/Mer, an NCAM-related receptor tyrosine kinase
    • Ling, L., Templeton, D., Kung, H. J. (1996) Identification of the major autophosphorylation sites of Nyk/Mer, an NCAM-related receptor tyrosine kinase. J. Biol. Chem. 271, 18355-18362.
    • (1996) J. Biol. Chem. , vol.271 , pp. 18355-18362
    • Ling, L.1    Templeton, D.2    Kung, H.J.3
  • 45
    • 0030740540 scopus 로고    scopus 로고
    • Intracellular signaling of the Ufo/Axl receptor tyrosine kinase is mediated mainly by a multisubstrate docking-site
    • Braunger, J., Schleithoff, L., Schulz, A. S., Kessler, H., Lammers, R., Ullrich, A., Bartram, C. R., Janssen, J. W. (1997) Intracellular signaling of the Ufo/Axl receptor tyrosine kinase is mediated mainly by a multisubstrate docking-site. Oncogene 14, 2619-2631.
    • (1997) Oncogene , vol.14 , pp. 2619-2631
    • Braunger, J.1    Schleithoff, L.2    Schulz, A.S.3    Kessler, H.4    Lammers, R.5    Ullrich, A.6    Bartram, C.R.7    Janssen, J.W.8
  • 46
    • 0029029248 scopus 로고
    • Cloning and developmental expression analysis of the murine c-mer tyrosine kinase
    • Graham, D. K., Bowman, G. W., Dawson, T. L., Stanford, W. L., Earp, H. S., Snodgrass, H. R. (1995) Cloning and developmental expression analysis of the murine c-mer tyrosine kinase. Oncogene 10, 2349-2359.
    • (1995) Oncogene , vol.10 , pp. 2349-2359
    • Graham, D.K.1    Bowman, G.W.2    Dawson, T.L.3    Stanford, W.L.4    Earp, H.S.5    Snodgrass, H.R.6
  • 47
    • 0029655520 scopus 로고    scopus 로고
    • Differential activation of the Ras/extracellular-signal-regulated protein kinase pathway is responsible for the biological consequences induced by the Axl receptor tyrosine kinase
    • Fridell, Y. W., Jin, Y., Quilliam, L. A., Burchert, A., McCloskey, P., Spizz, G., Varnum, B., Der, C., Liu, E. T. (1996) Differential activation of the Ras/extracellular-signal-regulated protein kinase pathway is responsible for the biological consequences induced by the Axl receptor tyrosine kinase. Mol. Cell. Biol. 16, 135-145.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 135-145
    • Fridell, Y.W.1    Jin, Y.2    Quilliam, L.A.3    Burchert, A.4    McCloskey, P.5    Spizz, G.6    Varnum, B.7    Der, C.8    Liu, E.T.9
  • 48
    • 0032926887 scopus 로고    scopus 로고
    • Biological effects of c-Mer receptor tyrosine kinase in hematopoietic cells depend on the Grb2 binding site in the receptor and activation of NF-κB
    • Georgescu, M. M., Kirsch, K. H., Shishido, T., Zong, C., Hanafusa, H. (1999) Biological effects of c-Mer receptor tyrosine kinase in hematopoietic cells depend on the Grb2 binding site in the receptor and activation of NF-κB. Mol. Cell. Biol. 19, 1171-1181.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 1171-1181
    • Georgescu, M.M.1    Kirsch, K.H.2    Shishido, T.3    Zong, C.4    Hanafusa, H.5
  • 49
    • 0037025316 scopus 로고    scopus 로고
    • Mer receptor tyrosine kinase signaling: Prevention of apoptosis and alteration of cytoskeletal architecture without stimulation of proliferation
    • Guttridge, K. L., Luft, J. C., Dawson, T. L., Kozlowska, E., Mahajan, N. P., Varnum, B., Earp, H. S. (2002) Mer receptor tyrosine kinase signaling: prevention of apoptosis and alteration of cytoskeletal architecture without stimulation of proliferation. J. Biol. Chem. 277, 24057-24066.
    • (2002) J. Biol. Chem. , vol.277 , pp. 24057-24066
    • Guttridge, K.L.1    Luft, J.C.2    Dawson, T.L.3    Kozlowska, E.4    Mahajan, N.P.5    Varnum, B.6    Earp, H.S.7
  • 50
    • 0142211201 scopus 로고    scopus 로고
    • An SH2 domain-dependent, phosphotyrosine-independent interaction between Vav1 and the Mer receptor tyrosine kinase: A mechanism for localizing guanine nucleotide-exchange factor action
    • Mahajan, N. P., Earp, H. S. (2003) An SH2 domain-dependent, phosphotyrosine-independent interaction between Vav1 and the Mer receptor tyrosine kinase: a mechanism for localizing guanine nucleotide-exchange factor action. J. Biol. Chem. 278, 42596-42603.
    • (2003) J. Biol. Chem. , vol.278 , pp. 42596-42603
    • Mahajan, N.P.1    Earp, H.S.2
  • 51
    • 0036223420 scopus 로고    scopus 로고
    • Vav regulates activation of Rac but not Cdc42 during FcγR-mediated phagocytosis
    • Patel, J. C., Hall, A., Caron, E. (2002) Vav regulates activation of Rac but not Cdc42 during FcγR-mediated phagocytosis. Mol. Biol. Cell 13, 1215-1226.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 1215-1226
    • Patel, J.C.1    Hall, A.2    Caron, E.3
  • 55
    • 0037111633 scopus 로고    scopus 로고
    • Vav1, but not Vav2, contributes to platelet aggregation by CRP and thrombin, but neither is required for regulation of phospholipase C
    • Pearce, A. C., Wilde, J. I., Doody, G. M., Best, D., Inoue, O., Vigorito, E., Tybulewicz, V. L., Turner, M., Watson, S. P. (2002) Vav1, but not Vav2, contributes to platelet aggregation by CRP and thrombin, but neither is required for regulation of phospholipase C. Blood 100, 3561-3569.
    • (2002) Blood , vol.100 , pp. 3561-3569
    • Pearce, A.C.1    Wilde, J.I.2    Doody, G.M.3    Best, D.4    Inoue, O.5    Vigorito, E.6    Tybulewicz, V.L.7    Turner, M.8    Watson, S.P.9
  • 56
    • 0034874686 scopus 로고    scopus 로고
    • Regulation of phospholipase C γ isoforms in haematopoietic cells: Why one, not the other?
    • Wilde, J. I., Watson, S. P. (2001) Regulation of phospholipase C γ isoforms in haematopoietic cells: why one, not the other? Cell. Signal. 13, 691-701.
    • (2001) Cell. Signal. , vol.13 , pp. 691-701
    • Wilde, J.I.1    Watson, S.P.2
  • 58
    • 0034194035 scopus 로고    scopus 로고
    • Apoptotic thymocyte clearance in scavenger receptor class A-deficient mice is apparently normal
    • Platt, N., Suzuki, H., Kodama, T., Gordon, S. (2000) Apoptotic thymocyte clearance in scavenger receptor class A-deficient mice is apparently normal. J. Immunol. 164, 4861-4867.
    • (2000) J. Immunol. , vol.164 , pp. 4861-4867
    • Platt, N.1    Suzuki, H.2    Kodama, T.3    Gordon, S.4
  • 60
    • 0034194271 scopus 로고    scopus 로고
    • Membrane cytoskeleton: PIP(2) pulls the strings
    • Nebl, T., Oh, S. W., Luna, E. J. (2000) Membrane cytoskeleton: PIP(2) pulls the strings. Curr. Biol. 10, R351-R354.
    • (2000) Curr. Biol. , vol.10
    • Nebl, T.1    Oh, S.W.2    Luna, E.J.3
  • 61
    • 0038311944 scopus 로고    scopus 로고
    • Phosphoinositide regulation of the actin cytoskeleton
    • Yin, H. L., Janmey, P. A. (2003) Phosphoinositide regulation of the actin cytoskeleton. Annu. Rev. Physiol. 65, 761-789.
    • (2003) Annu. Rev. Physiol. , vol.65 , pp. 761-789
    • Yin, H.L.1    Janmey, P.A.2
  • 62
    • 0028180858 scopus 로고
    • Tyrosine kinases Lyn and Syk regulate B cell receptor-coupled Ca2+ mobilization through distinct pathways
    • Takata, M., Sabe, H., Hata, A., Inazu, T., Homma, Y., Nukada, T., Yamamura, H., Kurosaki, T. (1994) Tyrosine kinases Lyn and Syk regulate B cell receptor-coupled Ca2+ mobilization through distinct pathways. EMBO J. 13, 1341-1349.
    • (1994) EMBO J. , vol.13 , pp. 1341-1349
    • Takata, M.1    Sabe, H.2    Hata, A.3    Inazu, T.4    Homma, Y.5    Nukada, T.6    Yamamura, H.7    Kurosaki, T.8
  • 63
    • 0030018304 scopus 로고    scopus 로고
    • A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-γ 2
    • Takata, M., Kurosaki, T. (1996) A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-γ 2. J. Exp. Med. 184, 31-40.
    • (1996) J. Exp. Med. , vol.184 , pp. 31-40
    • Takata, M.1    Kurosaki, T.2
  • 65
    • 0042941922 scopus 로고    scopus 로고
    • Syk activation is a leukotriene B4-regulated event involved in macrophage phagocytosis of IgG-coated targets but not apoptotic cells
    • Canetti, C., Hu, B., Curtis, J. L., Peters-Golden, M. (2003) Syk activation is a leukotriene B4-regulated event involved in macrophage phagocytosis of IgG-coated targets but not apoptotic cells. Blood 102, 1877-1883.
    • (2003) Blood , vol.102 , pp. 1877-1883
    • Canetti, C.1    Hu, B.2    Curtis, J.L.3    Peters-Golden, M.4
  • 66
    • 0027495890 scopus 로고
    • The regulation of phospholipase C γ1 by phosphatidic acid. Assessment of kinetic parameters
    • Jones, G. A., Carpenter, G. (1993) The regulation of phospholipase C γ1 by phosphatidic acid. Assessment of kinetic parameters. J. Biol. Chem. 268, 20845-20850.
    • (1993) J. Biol. Chem. , vol.268 , pp. 20845-20850
    • Jones, G.A.1    Carpenter, G.2
  • 67
    • 0033613921 scopus 로고    scopus 로고
    • Action of phosphatidylinositol-specific phospholipase Cγ1 on soluble and micellar substrates. Separating effects on catalysis from modulation of the surface
    • Zhou, C., Horstman, D., Carpenter, G., Roberts, M. F. (1999) Action of phosphatidylinositol-specific phospholipase Cγ1 on soluble and micellar substrates. Separating effects on catalysis from modulation of the surface. J. Biol. Chem. 274, 2786-2793.
    • (1999) J. Biol. Chem. , vol.274 , pp. 2786-2793
    • Zhou, C.1    Horstman, D.2    Carpenter, G.3    Roberts, M.F.4
  • 68
    • 0040313465 scopus 로고    scopus 로고
    • AHNAK, a protein that binds and activates phospholipase C-γ1 in the presence of arachidonic acid
    • Sekiya, F., Bae, Y. S., Jhon, D. Y., Hwang, S. C., Rhee, S. G. (1999) AHNAK, a protein that binds and activates phospholipase C-γ1 in the presence of arachidonic acid. J. Biol. Chem. 274, 13900-13907.
    • (1999) J. Biol. Chem. , vol.274 , pp. 13900-13907
    • Sekiya, F.1    Bae, Y.S.2    Jhon, D.Y.3    Hwang, S.C.4    Rhee, S.G.5
  • 70
    • 0019955375 scopus 로고
    • Phagocytosis of senescent neutrophils by human monocyte-derived macrophages and rabbit inflammatory macrophages
    • Newman, S. L., Henson, J. E., Henson, P. M. (1982) Phagocytosis of senescent neutrophils by human monocyte-derived macrophages and rabbit inflammatory macrophages. J. Exp. Med. 156, 430-442.
    • (1982) J. Exp. Med. , vol.156 , pp. 430-442
    • Newman, S.L.1    Henson, J.E.2    Henson, P.M.3
  • 71
    • 0041346077 scopus 로고    scopus 로고
    • Alveolar macrophages from subjects with chronic obstructive pulmonary disease are deficient in their ability to phagocytose apoptotic airway epithelial cells
    • Hodge, S., Hodge, G., Scicchitano, R., Reynolds, P. N., Holmes, M. (2003) Alveolar macrophages from subjects with chronic obstructive pulmonary disease are deficient in their ability to phagocytose apoptotic airway epithelial cells. Immunol. Cell Biol. 81, 289-296.
    • (2003) Immunol. Cell Biol. , vol.81 , pp. 289-296
    • Hodge, S.1    Hodge, G.2    Scicchitano, R.3    Reynolds, P.N.4    Holmes, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.