Biochemical evidence for conformational changes in the cross-talk between adenylation and peptidyl-carrier protein domains of nonribosomal peptide synthetases

FEBS Journal

Volumn 277, Issue 5, 2010, Pages 1159-1171

  Zettler, Joachim ^a   Mootz, Henning D ^a  

^a TU DORTMUND UNIVERSITY   (Germany)

Author keywords

A domain inhibitor; Conformational change; Domain interaction; Nonribosomal peptide synthetase (NRPS); Peptide antibiotics

Indexed keywords

GRAMICIDIN S SYNTHETASE; PANTETHEINE PHOSPHATE; PEPTIDE SYNTHASE; PEPTIDYL CARRIER PROTEIN;

ADENYLATION; ARTICLE; BIOCHEMISTRY; CHEMICAL LABELING; CHEMICAL MODIFICATION; CONFORMATIONAL TRANSITION; DNA TEMPLATE; GEL FILTRATION; MOLECULAR INTERACTION; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN;

AMINO ACID ISOMERASES; CARRIER PROTEINS; CATALYSIS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI; MODELS, MOLECULAR; MOLECULAR MIMICRY; MOLECULAR STRUCTURE; PEPTIDE SYNTHASES; PLASMIDS; POLYADENYLATION; POLYMERASE CHAIN REACTION; PROTEIN CONFORMATION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 76349088032     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2009.07551.x     Document Type: Article

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