-
1
-
-
0032006059
-
Microtubules and actin filaments: Dynamic targets for cancer chemotherapy
-
Jordan MA, Wilson L. Microtubules and actin filaments: dynamic targets for cancer chemotherapy. Curr Opin Cell Biol 1998;10:123-30.
-
(1998)
Curr Opin Cell Biol
, vol.10
, pp. 123-130
-
-
Jordan, M.A.1
Wilson, L.2
-
2
-
-
0027196777
-
Taxol induces internucleosomal DNA fragmentation associated with programmed cell death in human myeloid leukemia cells
-
Bhalla K, Ibrado AM, Tourkina E, Tang C, Mahoney ME, Huang Y. Taxol induces internucleosomal DNA fragmentation associated with programmed cell death in human myeloid leukemia cells. Leukemia 1993;7:563-8.
-
(1993)
Leukemia
, vol.7
, pp. 563-568
-
-
Bhalla, K.1
Ibrado, A.M.2
Tourkina, E.3
Tang, C.4
Mahoney, M.E.5
Huang, Y.6
-
3
-
-
0028983396
-
Paclitaxel (taxol) inhibits protein isoprenylation and induces apoptosis in PC-3 human prostate cancer cells
-
Danesi R, Figg WD, Reed E, Myers CE. Paclitaxel (taxol) inhibits protein isoprenylation and induces apoptosis in PC-3 human prostate cancer cells. Mol Pharmacol 1995;47:1106-11.
-
(1995)
Mol Pharmacol
, vol.47
, pp. 1106-1111
-
-
Danesi, R.1
Figg, W.D.2
Reed, E.3
Myers, C.E.4
-
4
-
-
0025651121
-
Disruption of microtubules induces an endogenous suicide pathway in human leukaemia HL-60 cells
-
Martin SJ, Cotter TG. Disruption of microtubules induces an endogenous suicide pathway in human leukaemia HL-60 cells. Cell Tissue Kinet 1990;23:545-59.
-
(1990)
Cell Tissue Kinet
, vol.23
, pp. 545-559
-
-
Martin, S.J.1
Cotter, T.G.2
-
5
-
-
0029328641
-
Taxol-induced mitotic block triggers rapid onset of a p53-independent apoptotic pathway
-
Woods CM, Zhu J, McQueney PA, Bollag D, Lazarides E. Taxol-induced mitotic block triggers rapid onset of a p53-independent apoptotic pathway. Mol Med 1995;1:506-26.
-
(1995)
Mol Med
, vol.1
, pp. 506-526
-
-
Woods, C.M.1
Zhu, J.2
McQueney, P.A.3
Bollag, D.4
Lazarides, E.5
-
6
-
-
58149347705
-
Microtubule active agents: Beyond the taxane frontier
-
Morris PG, Fornier MN. Microtubule active agents: beyond the taxane frontier. Clin Cancer Res 2008;14:7167-72.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7167-7172
-
-
Morris, P.G.1
Fornier, M.N.2
-
7
-
-
33750338449
-
Current state of the art of new tubulin inhibitors in the clinic
-
Kuppens IE. Current state of the art of new tubulin inhibitors in the clinic. Curr Clin Pharmacol 2006;1:57-70.
-
(2006)
Curr Clin Pharmacol
, vol.1
, pp. 57-70
-
-
Kuppens, I.E.1
-
8
-
-
0031936939
-
Levels of multidrug resistance (MDR1) P-glycoprotein expression by human breast cancer correlate with in vitro resistance to taxol and doxorubicin
-
Mechetner E, Kyshtoobayeva A, Zonis S, et al. Levels of multidrug resistance (MDR1) P-glycoprotein expression by human breast cancer correlate with in vitro resistance to taxol and doxorubicin. Clin Cancer Res 1998;4:389-98.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 389-398
-
-
Mechetner, E.1
Kyshtoobayeva, A.2
Zonis, S.3
-
9
-
-
0032842608
-
Overexpression of class I, II or IVb β-tubulin isotypes in CHO cells is insufficient to confer resistance to paclitaxel
-
Blade K, Menick DR, Cabral F. Overexpression of class I, II or IVb β-tubulin isotypes in CHO cells is insufficient to confer resistance to paclitaxel. J Cell Sci 1999;112:2213-21.
-
(1999)
J Cell Sci
, vol.112
, pp. 2213-2221
-
-
Blade, K.1
Menick, D.R.2
Cabral, F.3
-
10
-
-
38449097524
-
-
Fojo T, Menefee M. Mechanisms of multidrug resistance: the potential role of microtubule-stabilizing agents. Ann Oncol 2007;18 Suppl 5:v3-8.
-
Fojo T, Menefee M. Mechanisms of multidrug resistance: the potential role of microtubule-stabilizing agents. Ann Oncol 2007;18 Suppl 5:v3-8.
-
-
-
-
11
-
-
0028354777
-
Characterization of a human myeloid leukemia cell line highly resistant to taxol
-
Bhalla K, Huang Y, Tang C, et al. Characterization of a human myeloid leukemia cell line highly resistant to taxol. Leukemia 1994;8:465-75.
-
(1994)
Leukemia
, vol.8
, pp. 465-475
-
-
Bhalla, K.1
Huang, Y.2
Tang, C.3
-
13
-
-
0032883001
-
Molecular effects of paclitaxel: Myths and reality (a critical review)
-
Blagosklonny MV, Fojo T. Molecular effects of paclitaxel: myths and reality (a critical review). Int J Cancer 1999;83:151-6.
-
(1999)
Int J Cancer
, vol.83
, pp. 151-156
-
-
Blagosklonny, M.V.1
Fojo, T.2
-
15
-
-
0031466503
-
Involvement of p21 in mitotic exit after paclitaxel treatment in MCF-7 breast adenocarcinoma cell line
-
Barboule N, Chadebech P, Baldin V, Vidal S, Valette A. Involvement of p21 in mitotic exit after paclitaxel treatment in MCF-7 breast adenocarcinoma cell line. Oncogene 1997;15:2867-75.
-
(1997)
Oncogene
, vol.15
, pp. 2867-2875
-
-
Barboule, N.1
Chadebech, P.2
Baldin, V.3
Vidal, S.4
Valette, A.5
-
16
-
-
47949130625
-
Topoisomerase levels determine chemotherapy response in vitro and in vivo
-
Burgess DJ, Doles J, Zender L, et al. Topoisomerase levels determine chemotherapy response in vitro and in vivo. Proc Natl Acad Sci U S A 2008;105:9053-8.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 9053-9058
-
-
Burgess, D.J.1
Doles, J.2
Zender, L.3
-
17
-
-
0037370309
-
An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo
-
Hemann MT, Fridman JS, Zilfou JT, et al. An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo. Nat Genet 2003;33:396-400.
-
(2003)
Nat Genet
, vol.33
, pp. 396-400
-
-
Hemann, M.T.1
Fridman, J.S.2
Zilfou, J.T.3
-
18
-
-
27644582893
-
Probing tumor phenotypes using stable and regulated synthetic microRNA precursors
-
Dickins RA, Hemann MT, Zilfou JT, et al. Probing tumor phenotypes using stable and regulated synthetic microRNA precursors. Nat Genet 2005;37:1289-95.
-
(2005)
Nat Genet
, vol.37
, pp. 1289-1295
-
-
Dickins, R.A.1
Hemann, M.T.2
Zilfou, J.T.3
-
19
-
-
0042926426
-
Association between mitotic spindle checkpoint impairment and susceptibility to the induction of apoptosis by anti-microtubule agents in human lung cancers
-
Masuda A, Maeno K, Nakagawa T, Saito H, Takahashi T. Association between mitotic spindle checkpoint impairment and susceptibility to the induction of apoptosis by anti-microtubule agents in human lung cancers. Am J Pathol 2003;163:1109-16.
-
(2003)
Am J Pathol
, vol.163
, pp. 1109-1116
-
-
Masuda, A.1
Maeno, K.2
Nakagawa, T.3
Saito, H.4
Takahashi, T.5
-
20
-
-
1942474378
-
Dependence of paclitaxel sensitivity on a functional spindle assembly checkpoint
-
Sudo T, Nitta M, Saya H, Ueno NT. Dependence of paclitaxel sensitivity on a functional spindle assembly checkpoint. Cancer Res 2004;64:2502-8.
-
(2004)
Cancer Res
, vol.64
, pp. 2502-2508
-
-
Sudo, T.1
Nitta, M.2
Saya, H.3
Ueno, N.T.4
-
21
-
-
0037427074
-
MAD2-induced sensitization to vincristine is associated with mitotic arrest and Raf/Bcl-2 phosphorylation in nasopharyngeal carcinoma cells
-
Wang X, Jin DY, Wong HL, Feng H, Wong YC, Tsao SW. MAD2-induced sensitization to vincristine is associated with mitotic arrest and Raf/Bcl-2 phosphorylation in nasopharyngeal carcinoma cells. Oncogene 2003;22:109-16.
-
(2003)
Oncogene
, vol.22
, pp. 109-116
-
-
Wang, X.1
Jin, D.Y.2
Wong, H.L.3
Feng, H.4
Wong, Y.C.5
Tsao, S.W.6
-
23
-
-
0023809123
-
Microtubule changes and cytotoxicity in leukemic cell lines treated with taxol
-
Rowinsky EK, Donehower RC, Jones RJ, Tucker RW. Microtubule changes and cytotoxicity in leukemic cell lines treated with taxol. Cancer Res 1988;48:4093-100.
-
(1988)
Cancer Res
, vol.48
, pp. 4093-4100
-
-
Rowinsky, E.K.1
Donehower, R.C.2
Jones, R.J.3
Tucker, R.W.4
-
24
-
-
0020328750
-
Taxol inhibits the nuclear movements during fertilization and induces asters in unfertilized sea urchin eggs
-
Schatten G, Schatten H, Bestor TH, Balczon R. Taxol inhibits the nuclear movements during fertilization and induces asters in unfertilized sea urchin eggs. J Cell Biol 1982;94:455-65.
-
(1982)
J Cell Biol
, vol.94
, pp. 455-465
-
-
Schatten, G.1
Schatten, H.2
Bestor, T.H.3
Balczon, R.4
-
25
-
-
48449098623
-
Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs
-
Gascoigne KE, Taylor SS. Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs. Cancer Cell 2008;14:111-22.
-
(2008)
Cancer Cell
, vol.14
, pp. 111-122
-
-
Gascoigne, K.E.1
Taylor, S.S.2
-
26
-
-
0035949576
-
Resistance to Taxol in lung cancer cells associated with increased microtubule dynamics
-
Goncalves A, Braguer D, Kamath K, et al. Resistance to Taxol in lung cancer cells associated with increased microtubule dynamics. Proc Natl Acad Sci U S A 2001;98:11737-42.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 11737-11742
-
-
Goncalves, A.1
Braguer, D.2
Kamath, K.3
-
27
-
-
0033826530
-
Genetic analysis of chemoresistance in primary murine lymphomas
-
Schmitt CA, Rosenthal CT, Lowe SW. Genetic analysis of chemoresistance in primary murine lymphomas. Nat Med 2000;6:1029-35.
-
(2000)
Nat Med
, vol.6
, pp. 1029-1035
-
-
Schmitt, C.A.1
Rosenthal, C.T.2
Lowe, S.W.3
-
28
-
-
0016789438
-
Mitotic mutants of Aspergillus nidulans
-
Morris NR. Mitotic mutants of Aspergillus nidulans. Genet Res 1975;26:237-54.
-
(1975)
Genet Res
, vol.26
, pp. 237-254
-
-
Morris, N.R.1
-
30
-
-
40549126830
-
Mitotic regulation by NIMA-related kinases
-
O'Regan L, Blot J, Fry AM. Mitotic regulation by NIMA-related kinases. Cell Div 2007;2:25.
-
(2007)
Cell Div
, vol.2
, pp. 25
-
-
O'Regan, L.1
Blot, J.2
Fry, A.M.3
-
31
-
-
29244456404
-
Caught Nek-ing: Cilia and centrioles
-
Quarmby LM, Mahjoub MR. Caught Nek-ing: cilia and centrioles. J Cell Sci 2005;118:5161-9.
-
(2005)
J Cell Sci
, vol.118
, pp. 5161-5169
-
-
Quarmby, L.M.1
Mahjoub, M.R.2
-
32
-
-
38649138030
-
Phylogenetic analysis of the Neks reveals early diversification of ciliary-cell cycle kinases
-
Parker JD, Bradley BA, Mooers AO, Quarmby LM. Phylogenetic analysis of the Neks reveals early diversification of ciliary-cell cycle kinases. PLoS One 2007;2:e1076.
-
(2007)
PLoS One
, vol.2
-
-
Parker, J.D.1
Bradley, B.A.2
Mooers, A.O.3
Quarmby, L.M.4
-
33
-
-
38749117137
-
A role for altered microtubule polymer levels in vincristine resistance of childhood acute lymphoblastic leukemia xenografts
-
Ong V, Liem NL, Schmid MA, et al. A role for altered microtubule polymer levels in vincristine resistance of childhood acute lymphoblastic leukemia xenografts. J Pharmacol Exp Ther 2008;324:434-42.
-
(2008)
J Pharmacol Exp Ther
, vol.324
, pp. 434-442
-
-
Ong, V.1
Liem, N.L.2
Schmid, M.A.3
-
34
-
-
0025872827
-
Resistance to antimitotic drugs in Chinese hamster ovary cells correlates with changes in the level of polymerized tubulin
-
Minotti AM, Barlow SB, Cabral F. Resistance to antimitotic drugs in Chinese hamster ovary cells correlates with changes in the level of polymerized tubulin. J Biol Chem 1991;266:3987-94.
-
(1991)
J Biol Chem
, vol.266
, pp. 3987-3994
-
-
Minotti, A.M.1
Barlow, S.B.2
Cabral, F.3
-
35
-
-
0032904694
-
Antisense oligonucleotides to class III β-tubulin sensitize drug-resistant cells to Taxol
-
Kavallaris M, Burkhart CA, Horwitz SB. Antisense oligonucleotides to class III β-tubulin sensitize drug-resistant cells to Taxol. Br J Cancer 1999;80:1020-5.
-
(1999)
Br J Cancer
, vol.80
, pp. 1020-1025
-
-
Kavallaris, M.1
Burkhart, C.A.2
Horwitz, S.B.3
-
36
-
-
0035422780
-
Multiple microtubule alterations are associated with Vinca alkaloid resistance in human leukemia cells
-
Kavallaris M, Tait AS, Walsh BJ, et al. Multiple microtubule alterations are associated with Vinca alkaloid resistance in human leukemia cells. Cancer Res 2001;61:5803-9.
-
(2001)
Cancer Res
, vol.61
, pp. 5803-5809
-
-
Kavallaris, M.1
Tait, A.S.2
Walsh, B.J.3
-
37
-
-
0028347226
-
Characterization of a taxol- resistant human small-cell lung cancer cell line
-
Ohta S, Nishio K, Kubota N, et al. Characterization of a taxol- resistant human small-cell lung cancer cell line. Jpn J Cancer Res 1994;85:290-7.
-
(1994)
Jpn J Cancer Res
, vol.85
, pp. 290-297
-
-
Ohta, S.1
Nishio, K.2
Kubota, N.3
|