Preventive effect of chronic endothelin type A receptor antagonist on coronary microvascular spasm induced by repeated epicardial coronary artery endothelial denudation in pigs

Journal of Atherosclerosis and Thrombosis

Volumn 17, Issue 1, 2010, Pages 54-63

  Osugi, Taku ^a   Saitoh, Shu Ichi ^a   Matumoto, Ken ^a   Muto, Mituru ^a   Aikawa, Kazuhiko ^a   Ohkawara, Hiroshi ^a   Sugimoto, Kouichi ^a   Kamioka, Masashi ^a   Ishibashi, Toshiyuki ^a   Maruyama, Yukio ^b  

^a FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^b HOSHI GENERAL HOSPITAL   (Japan)

Author keywords

Coronary microvascular spasm; Endothelin type A receptor; Endothelin 1; Free radical

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; N [6 [2 (5 BROMO 2 PYRIMIDINYLOXY)ETHOXY] 5 (4 METHYLPHENYL) 4 PYRIMIDINYL] 4 (2 HYDROXY 1,1 DIMETHYLETHYL)BENZENESULFONAMIDE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA PRESSURE; ARTERIAL WALL THICKNESS; ARTERY DIAMETER; ARTICLE; BODY WEIGHT; COMPARATIVE STUDY; CONTROLLED STUDY; CORONARY ARTERY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY SPASM; CORONARY VASCULAR RESISTANCE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG INDUCED DISEASE; FLOWMETER; HEART MUSCLE; HEART PROTECTION; HISTOPATHOLOGY; IMPLANTATION; LEFT ANTERIOR DESCENDING CORONARY ARTERY; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; SWINE; VASCULAR SURGERY;

EID: 76249111451     PISSN: 13403478     EISSN: 18803873     Source Type: Journal    
DOI: 10.5551/jat.2147     Document Type: Article

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