Effect of gonadectomy on the metabolism of arachidonic acid in isolated kidney of a rat model of metabolic syndrome

Metabolism: Clinical and Experimental

Volumn 59, Issue 3, 2010, Pages 414-423

  Pérez Torres, Israel ^a   El Hafidi, Mohammed ^a   Pavón, Natalia ^a   Infante, Oscar ^a   Avila Casado, Maria C ^a   Baños, Guadalupe ^a  

^a INSTITUTO NACIONAL DE CARDIOLOGÍA IGNACIO CHÁVEZ   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; ESTRADIOL; INDOMETACIN; PROSTAGLANDIN E2; TESTOSTERONE; THROMBOXANE B2;

ALBUMINURIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARACHIDONIC ACID METABOLISM; ARTICLE; CONTROLLED STUDY; ESTRADIOL BLOOD LEVEL; FEMALE; GONADECTOMY; KIDNEY; KIDNEY INJURY; KIDNEY PERFUSION; MALE; METABOLIC SYNDROME X; NONHUMAN; OVARIECTOMY; PERFUSION PRESSURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SYSTOLIC BLOOD PRESSURE; TESTOSTERONE BLOOD LEVEL; URINALYSIS;

ABDOMINAL FAT; ALBUMINURIA; ANIMALS; ARACHIDONIC ACID; BLOOD PRESSURE; BLOTTING, WESTERN; BODY WEIGHT; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; ESTRADIOL; FEMALE; KIDNEY; MALE; METABOLIC SYNDROME X; MICROSOMES; ORCHIECTOMY; OVARIECTOMY; PROSTAGLANDINS; RATS; RATS, WISTAR; SEX CHARACTERISTICS; TESTOSTERONE;

EID: 76249107684     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.metabol.2009.08.014     Document Type: Article

References (74)

1. Segura J., Campo C., Roldán C., et al. Hypertensive renal damage in metabolic syndrome is associated with glucose metabolism disturbances. J Am Soc Nephrol 15 (2004) S37-S42
2. Busserolles J., Mazur A., Gueux E., et al. Metabolic syndrome in the rat: females are protected against the pro-oxidant effect of a high sucrose diet. Exp Biol Med 227 (2002) 837-842
3. Cárdenas G., Torres J., Zamora J., et al. Isolated heart function after ischemia and reperfusion in sucrose-fed rats: influence of gender and treatment. Clin Exp Hypertens 28 (2006) 85-107
4. Isles C. Blood pressure in males and females. J Hypertens 13 (1995) 285-290
5. Bloomgarden Z. Diabetic nephropathy. Diabetes Care 3 (2005) 745-751
6. Park K., Kim J., Ahn Y., Bonventre A.J., Bonventre J.V., et al. Testosterone is responsible for enhanced susceptibility of males to ischemic renal injury. J Biol Chem 279 (2004) 52282-52292
7. Reckelhoff J.F. Sex steroids, cardiovascular disease, and hypertension. Hypertension 45 (2005) 170-174
8. McGuire B., Watson W., Pérez F., et al. Gender differences in the renin-angiotensin and nitric oxide systems: relevance in the normal and diseased kidney. Kidney Blood Press Res 30 (2007) 67-80
9. Nielsen C., Flyvbjerg A., Bruun J., et al. Decreases in renal functional reserve and proximal tubular fluid output in conscious oophorectomized rats: normalization with sex hormone substitution. J Am Soc Nephrol 14 (2003) 3102-3110
10. Quilley J., and Chen Y. Role of COX-2 in the enhanced vasoconstrictor effect of arachidonic acid in the diabetic rat kidney. Hypertension 42 (2003) 837-843
11. Marnett L., Rowlinson S., Goodwin D., et al. Arachidonic acid oxygenation by COX-1 and COX-2. J Biol Chem 274 (1999) 22903-22906
12. Pomposiello S., Quilley J., Carroll M., et al. 5,6-Epoxyeicosatrienoic acid mediates the enhanced renal vasodilation to arachidonic acid in the SHR. Hypertension 42 (2003) 548-554
13. Harris R., McKanna J., Akai Y., et al. Cyclooxygenase-2 is associated with the macula densa in rat kidney and increases with salt restriction. J Clin Invest 94 (1994) 2504-2510
14. Dubois R., Abramson S., Crofford L., et al. Cyclooxygenase in biology and disease. FASEB J 12 (1998) 1063-1073
15. Hao C.M., and Breyer M.D. Hypertension and cyclooxygenase-2 inhibitors target: the renal medulla. Hypertension 44 (2004) 396-397
16. Locatelli F., Pozzoni P., and Vecchio L. Renal manifestations in the metabolic syndrome. J Am Soc Nephrol 17 (2006) S81-S85
17. Giltay E., Duschek E., Katan M., et al. Raloxifene and hormone replacement therapy increase arachidonic acid and docosahexaenoic acid levels in postmenopausal women. J Endocrinol 182 (2004) 399-4089
18. Ichihara A., Imig J., and Navar L. Cyclooxygenase-2 modulates afferent arteriolar responses to increases in pressure. Hypertension 34 (1999) 843-847
19. Reaven G., and Ho H. Sugar-induced hypertension in Sprague-Dawley rats. Am J Hypertens 4 (1991) 610-614
20. Baños G., Carvajal K., Cardoso G., et al. Vascular reactivity and effect of serum in a rat model of hypertriglyceridemia and hypertension. Am J Hypertens 10 (1997) 379-388
21. Baños G., and El Hafidi M. Models of experimental hypertension. In: Benhagen E.F. (Ed). Hypertension new research (2006), Nova Science Publishers Inc, New York 1-46
22. El Hafidi M., Pérez I., Carrillo S., et al. Effect of sex hormones on non-esterified fatty acids, intra-abdominal fat accumulation, and hypertension induced by sucrose diet in male rats. Clin Exp Hypertens 28 (2006) 669-681
23. Pérez I., El Hafidi M., Zamora-González J., et al. Modulation of aortic vascular reactivity by sex hormones in a male rat model of metabolic syndrome. Life Sci 80 (2007) 2170-2180
24. Pérez I., El Hafidi M., Infante O., et al. Effects of sex hormone levels on aortic vascular reactivity and variables associated with the metabolic syndrome in sucrose-fed female rats. Can J Physiol Pharmacol 86 (2008) 25-35
25. BenGershôm E. Screening for albuminuria: a case for estimation of albumin in urine. Clin Chem 21 (1975) 1795-1798
26. Vázquez-Cruz B., López P., Talamas-Rohana P., et al. Increased renal vasoconstriction and gene expression of cyclooxygenase-1 in renovascular hypertension. J Cardiovasc Pharmacol 36 (2000) 577-583
27. Folch J., Lees M., and Sloane-Stanley G.H. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 22 (1957) 697-709
28. Pérez I., El Hafidi M., Sanchez C., et al. Effect or sugar-induced hypertension in rats on the pattern of serum arachidonic, dihomo-γ-linoleic and linoleic acids. Med Sci Res 27 (1999) 847-849
29. Bray G.A. Obesity and reproduction. Hum Reprod 12 (1997) 26-32
30. Nilsson C., Niklasson M., Erikssson E., Bjorntorp P., and Holmang A. Imprinting of female offspring with testosterone results in insulin resistance and changes in body fat distribution at adult age in rats. J Clin Invest 101 (1998) 74-78
31. Deroo B., and Korach K. Estrogen receptors and human disease. J Clin Invest 116 (2006) 561-570
32. Baños G., Medina-Campos O., Maldonado P., et al. Antioxidant enzymes in hypertensive and hypertriglyceridemic rats: effect of gender. Clin Exp Hypertens 1 (2005) 45-57
33. Reckelhoff J.F., Zhang H., and Granger J.P. Testosterone exacerbates hypertension and reduces pressure-natriuresis in male spontaneously hypertensive rats. Hypertension 31 (1998) 435-439
34. Jones R.D., Jones T.H., and Channer K.S. The influence of testosterone upon vascular reactivity. Eur J Endocrinol 151 (2004) 29-37
35. Zhao H., Tian Z., Hao J., and Chen B. Extragonadal aromatization increases with time after ovariectomy in rats. Reprod Biol Endocrinol 3 (2005) 6
36. Ward G.R., and Abdel-Rahman A.A. Effect of testosterone replacement or duration of castration on baroreflex bradycardia in conscious rats. BMC Pharmacol 5 (2005) 9
37. Vasudevan H., Negareddy P., and McNeill J. Gonadectomy prevents endothelial dysfunction in fructose-fed male rats, a factor contributing to the development of hypertension. Am J Physiol Heart Circ Physiol 291 (2006) H3058-H3064
38. Okumura M., Imanishi M., Yamashita T., Yamamura Y., Kim S., Iwao H., et al. Renal production of thromboxane and prostaglandins in a rat model of type 2 diabetes. Life Sci 66 (2000) 371-377
39. Ospina J., Krause D., and Duckles S. 17-Estradiol increases rat cerebrovascular prostacyclin synthesis by elevating cyclooxygenase-1 and prostacyclin synthase. Stroke 33 (2002) 600-605
40. Wu F., and Eckardstein A. Androgens and coronary artery disease. Endocr Rev 24 (2003) 183-217
41. Galipeau D., Arikawa E., Sekirov I., and McNeill J.H. Chronic thromboxane synthase inhibition prevents fructose-induced hypertension. Hypertension 38 (2001) 872-876
42. Cheuk B., Leung P., Lo A., and Wong P.Y. Androgen control of cyclooxygenase expression in the rat epididymis. Biol Reprod 63 (2000) 775-780
43. Fulton C., and Stallone J. Sexual dimorphism in prostanoid-potentiated vascular contraction: roles of endothelium and ovarian steroids. Am J Physiol Heart Circ Physiol 283 (2002) H2062-H2073
44. Quan A., Chakravarty S., Chen J.C., Chen J.C., Loleh S., Saini N., et al. Androgens augment proximal tubule transport. Am J Physiol Renal Physiol 287 (2004) F452-F459
45. Chen Y.F., Naftilan A.J., and Oparil S. Androgen-dependent angiotensinogen and renin messenger RNA expression in hypertensive rats. Hypertension 19 (1992) 456-463
46. Dean S.A., Tan J., O'Brien E.R., and Leenen F.H. 17beta-Estradiol downregulates tissue angiotensin-converting enzyme and ANG II type 1 receptor in female rats. Am J Physiol Regul Integr Comp Physiol 288 (2005) R759-R766
47. Lemos C.C., Mandarim-de-Lacerda A., Dorigo D., et al. Chronic renal failure in male and female rats. J Nephrol 18 (2005) 368-373
48. Reckelhoff J.F. Gender differences in the regulation of blood pressure. Hypertension 37 (2001) 1199-1208
49. Hall J.E., Crook E.D., Jones D.W., et al. Mechanisms of obesity-associated cardiovascular and renal disease. Am J Med Sci 234 (2002) 127-137
50. Orth S., and Ritz E. The nephritic syndrome. N Engl J Med 338 (1998) 1202-1211
51. Sowers J.R., Epstein M., and Frohlich E.D. Diabetes, hypertension and cardiovascular disease: an update. Hypertension 37 (2001) 1053-1059
52. Neugarten J. Gender and the progression of renal disease. J Am Soc Nephrol 13 (2002) 2807-2809
53. Sakemi T., Toyoshima H., and Morito F. Testosterone eliminates the attenuating effect of castration on the progressive glomerular injury in hypercholesterolemic male Imai rats. Nephron 67 (1994) 469-476
54. Fortepiani L.A., Yanes L., Zhang H., et al. Role of androgens in mediating renal injury in aging SHR. Hypertension 42 (2003) 952-955
55. Tajiri Y., Inoguchi T., Umeda F., et al. Reduction urinary albumin excretion by thromboxane synthetase inhibitor, OKY-046, through modulating renal prostaglandins in patients with diabetic nephropathy. Diabetes Res Clin Pract 10 (1990) 231-239
56. Song D., Arikawa E., Galipeau D., et al. Androgens are necessary for the development of fructose-induced hypertension. Hypertension 43 (2004) 667-672
57. Sullivan J.C., Sasser J.M., Pollock D.M., et al. Sexual dimorphism in renal production of prostanoids in spontaneously hypertensive rats. Hypertension 45 (2005) 406-411
58. Silbiger S., Lei J., Neugarten J., and Estradiol suppresses type I. Collagen synthesis in mesangial cells via activation of activator protein-1. Kidney Int 4 (1999) 1268-1276
59. Sheridan A.M., and Bonventre J.V. Pathophysiology of ischemic acute renal failure. Contrib Nephrol 132 (2001) 7-21
60. Moorhead J.F., Chan M.K., El-Nahas M., et al. Lipid nephrotoxicity in chronic progressive glomerular and tubulo-interstitial disease. Lancet 2 (1982) 1309-1311
61. Fried L.F., Orchard T.J., and Kasiske B.L. Effect of lipid reduction on the progression of renal disease: a meta-analysis. Kidney Int 59 (2001) 260-269
62. El Hafidi M., Pérez I., Zamora J., et al. Glycine intake decreases plasma free fatty acids, adipose cell size, and blood pressure in sucrose-fed rats. Am J Physiol Regul Integr Comp Physiol 287 (2004) R1387-R1393
63. Williams B., and Schrier R. Glucose-induced protein kinase C activity regulates arachidonic acid release and eicosanoid production by cultured glomerular mesangial cells. J Clin Invest 92 (1993) 2889-2896
64. Rupnow H.L., Phernetton T.M., Modrick M.L., et al. Endothelial vasodilator production by uterine and systemic arteries. VIII. Estrogen and progesterone effects on cPLA2, COX-1, and PGIS protein expression. Biol Reprod 66 (2002) 468-474
65. Muirhead E.E., Rightsel W.A., Leach B.E., et al. Reversal of hypertension by transplants and lipid extracts of cultured renomedullary interstitial cells. Lab Invest 36 (1977) 162-172
66. Yanagisawa H., Morrissey J., and Klahr S. Mechanism of enhanced eicosanoid production by isolated glomeruli from rats with bilateral ureteral obstruction. Am J Physiol 261 (1991) F248-F255
67. Imig J. Eicosanoid regulation of renal vasculature. Am J Physiol Renal Physiol 279 (2000) F965-F981
68. Caughey G.E., Cleland C.G., Penglis P.S., et al. Roles of cyclooxygenase COX-1 and COX-2 in prostanoid production by human endothelial cells: selective upregulation of prostacyclin synthesis by COX-2. J Immunol 167 (2001) 2831-2838
69. Baber S.R., Deng W., Rodriguez J., et al. Vasoactive prostanoids are generated from arachidonic acid by COX-1 and COX-2 in the mouse. Am J Physiol Heart Circ Physiol 289 (2005) H1476-H1487
70. Orshal J., and Khalil R. Gender, sex hormones, and vascular tone. Am J Physiol Regul Integr Comp Physiol 286 (2004) R233-R249
71. Maggi F.M., Tyrrell N., Maddox Y., Watkins W., Ramey E.R., and Ramwell P.W. Prostaglandin synthetase activity in vascular tissue of male and female rats. Prostaglandins 19 (1980) 985-993
72. Ishizuka T., Ito O., Omata K., et al. Role of androgens in the renal production of 20-hydroxyeicosatetraenoic acid in spontaneously hypertensive rats. Nippon Jinzo Gakkai Shi 46 (2004) 685-692
73. Zhou Y., Lin S., Chang H.H., et al. Gender differences of renal CYP-derived eicosanoid synthesis in rats fed a high-fat diet. Am J Hypertens 18 (2005) 530-537
74. Holla V., Adas F., Imig J., et al. Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension. PNAS 98 (2001) 5211-5216