Missense mutations in IHH impair Indian hedgehog signaling in C3H10T1/2 cells: Implications for brachydactyly type A1, and new targets for hedgehog signaling

Cellular and Molecular Biology Letters

Volumn 15, Issue 1, 2010, Pages 153-176

  Guo, Shengzhen ^a,b,c   Zhou, Jian ^a,b   Gao, Bo ^a,b,c   Hu, Jianxin ^a,b,c   Wang, Hongsheng ^a,b   Meng, Junwei ^a,b   Zhao, Xinzhi ^a,b   Ma, Gang ^a,b   Lin, Chuwen ^a,b   Xiao, Yue ^a,b   Tang, Wei ^a,b   Zhu, Xuming ^a,b   Cheah, Kathryn S E ^c   Feng, Guoying ^d   Chan, Danny ^c   He, Lin ^a,b,e  

^a Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

^d Shanghai Institutes of Mental Health   (China)

^e FUDAN UNIVERSITY   (China)

Author keywords

Brachydactyly type A1; EMSA; Indian hedgehog; Microarray

Indexed keywords

BONE MORPHOGENETIC PROTEIN; PREPROENKEPHALIN; PROTEIN PATCHED 1; REGULATOR PROTEIN; SCLEROSTIN; SOMATOMEDIN BINDING PROTEIN 5; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; BRACHYDACTYLY; BRACHYDACTYLY TYPE A1; CONTROLLED STUDY; EMBRYO; FINGER; GENE CONTROL; GENE EXPRESSION; GENE INDUCTION; GENE TARGETING; JOINT; LOSS OF FUNCTION MUTATION; MICROARRAY ANALYSIS; MISSENSE MUTATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ERINACEIDAE;

EID: 76149118077     PISSN: 14258153     EISSN: 16891392     Source Type: Journal    
DOI: 10.2478/s11658-009-0040-2     Document Type: Article

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