-
2
-
-
0034045298
-
Epidemiology of sarcopenia
-
Melton 3rd LJ, Khosla S, Crowson CS, O'Connor MK, O'Fallon WM, Riggs BL 2000 Epidemiology of sarcopenia. J Am Geriatr Soc 48:625-630
-
(2000)
J Am Geriatr Soc
, vol.48
, pp. 625-630
-
-
Melton 3rd, L.J.1
Khosla, S.2
Crowson, C.S.3
O'Connor, M.K.4
O'Fallon, W.M.5
Riggs, B.L.6
-
3
-
-
17244363631
-
Decline in skeletal muscle mitochondrial function with aging in humans
-
Short KR, Bigelow ML, Kahl J, Singh R, Coenen-Schimke J, Raghavakaimal S, Nair KS 2005 Decline in skeletal muscle mitochondrial function with aging in humans. Proc Natl Acad Sci USA 102: 5618-5623
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 5618-5623
-
-
Short, K.R.1
Bigelow, M.L.2
Kahl, J.3
Singh, R.4
Coenen-Schimke, J.5
Raghavakaimal, S.6
Nair, K.S.7
-
4
-
-
0038025371
-
Mitochondrial dysfunction in the elderly: Possible role in insulin resistance
-
Petersen KF, Befroy D, Dufour S, Dziura J, Ariyan C, Rothman DL, DiPietro L, Cline GW, Shulman GI 2003 Mitochondrial dysfunction in the elderly: possible role in insulin resistance. Science 300:1140-1142
-
(2003)
Science
, vol.300
, pp. 1140-1142
-
-
Petersen, K.F.1
Befroy, D.2
Dufour, S.3
Dziura, J.4
Ariyan, C.5
Rothman, D.L.6
DiPietro, L.7
Cline, G.W.8
Shulman, G.I.9
-
5
-
-
0042266366
-
Impact of aerobic exercise training on age-related changes in insulin sensitivity and muscle oxidative capacity
-
Short KR, Vittone JL, Bigelow ML, Proctor DN, Rizza RA, Coenen-Schimke JM, Nair KS 2003 Impact of aerobic exercise training on age-related changes in insulin sensitivity and muscle oxidative capacity. Diabetes 52:1888-1896
-
(2003)
Diabetes
, vol.52
, pp. 1888-1896
-
-
Short, K.R.1
Vittone, J.L.2
Bigelow, M.L.3
Proctor, D.N.4
Rizza, R.A.5
Coenen-Schimke, J.M.6
Nair, K.S.7
-
6
-
-
0030451773
-
Effect of age on in vivo rates of mitochondrial protein synthesis in human skeletal muscle
-
Rooyackers OE, Adey DB, Ades PA, Nair KS 1996 Effect of age on in vivo rates of mitochondrial protein synthesis in human skeletal muscle. Proc Natl Acad Sci USA 93:15364-15369
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 15364-15369
-
-
Rooyackers, O.E.1
Adey, D.B.2
Ades, P.A.3
Nair, K.S.4
-
7
-
-
0036297809
-
Use of amino acids as growth hormone-releasing agents by athletes
-
Chromiak JA, Antonio J 2002 Use of amino acids as growth hormone-releasing agents by athletes. Nutrition 18:657-661
-
(2002)
Nutrition
, vol.18
, pp. 657-661
-
-
Chromiak, J.A.1
Antonio, J.2
-
8
-
-
0043268873
-
Protein and amino acid supplementation in athletes
-
Armsey Jr TD, Grime TE 2002 Protein and amino acid supplementation in athletes. Curr Sports Med Rep 1:253-256
-
(2002)
Curr Sports Med Rep
, vol.1
, pp. 253-256
-
-
Armsey Jr, T.D.1
Grime, T.E.2
-
9
-
-
0037224768
-
The role of leucine in weight loss diets and glucose homeostasis
-
Layman DK 2003 The role of leucine in weight loss diets and glucose homeostasis. J Nutr 133:261S-267S
-
(2003)
J Nutr
, vol.133
-
-
Layman, D.K.1
-
11
-
-
13844266552
-
Effect of nutritional supplements on wound healing in home-nursed elderly: A randomized trial
-
Collins CE, Kershaw J, Brockington S 2005 Effect of nutritional supplements on wound healing in home-nursed elderly: a randomized trial. Nutrition 21:147-155
-
(2005)
Nutrition
, vol.21
, pp. 147-155
-
-
Collins, C.E.1
Kershaw, J.2
Brockington, S.3
-
12
-
-
0032080924
-
Exogenous amino acids stimulate net muscle protein synthesis in the elderly
-
Volpi E, Ferrando AA, Yeckel CW, Tipton KD, Wolfe RR 1998 Exogenous amino acids stimulate net muscle protein synthesis in the elderly. J Clin Invest 101:2000-2007
-
(1998)
J Clin Invest
, vol.101
, pp. 2000-2007
-
-
Volpi, E.1
Ferrando, A.A.2
Yeckel, C.W.3
Tipton, K.D.4
Wolfe, R.R.5
-
13
-
-
33750102079
-
Co-ingestion of protein and leucine stimulates muscle protein synthesis rates to the same extent in young and elderly lean men
-
Koopman R, Verdijk L, Manders RJ, Gijsen AP, Gorselink M, Pijpers E, Wagenmakers AJ, van Loon LJ 2006 Co-ingestion of protein and leucine stimulates muscle protein synthesis rates to the same extent in young and elderly lean men. Am J Clin Nutr 84:623-632
-
(2006)
Am J Clin Nutr
, vol.84
, pp. 623-632
-
-
Koopman, R.1
Verdijk, L.2
Manders, R.J.3
Gijsen, A.P.4
Gorselink, M.5
Pijpers, E.6
Wagenmakers, A.J.7
van Loon, L.J.8
-
14
-
-
0042068305
-
Essential amino acids are primarily responsible for the amino acid stimulation of muscle protein anabolism in healthy elderly adults
-
Volpi E, Kobayashi H, Sheffield-Moore M, Mittendorfer B, Wolfe RR 2003 Essential amino acids are primarily responsible for the amino acid stimulation of muscle protein anabolism in healthy elderly adults. Am J Clin Nutr 78:250-258
-
(2003)
Am J Clin Nutr
, vol.78
, pp. 250-258
-
-
Volpi, E.1
Kobayashi, H.2
Sheffield-Moore, M.3
Mittendorfer, B.4
Wolfe, R.R.5
-
15
-
-
66149141889
-
Amino acid supplementation increases lean body mass, basal muscle protein synthesis, and insulin-like growth factor-I expression in older women
-
Dillon EL, Sheffield-Moore M, Paddon-Jones D, Gilkison C, Sanford AP, Casperson SL, Jiang J, Chinkes DL, Urban RJ 2009 Amino acid supplementation increases lean body mass, basal muscle protein synthesis, and insulin-like growth factor-I expression in older women. Journal of Clin Endocrinol Metab 94:1630-1637
-
(2009)
Journal of Clin Endocrinol Metab
, vol.94
, pp. 1630-1637
-
-
Dillon, E.L.1
Sheffield-Moore, M.2
Paddon-Jones, D.3
Gilkison, C.4
Sanford, A.P.5
Casperson, S.L.6
Jiang, J.7
Chinkes, D.L.8
Urban, R.J.9
-
16
-
-
0038271638
-
Effect of insulin on human skeletal muscle mitochondrial ATP production, protein synthesis, and mRNA transcripts
-
Stump CS, Short KR, Bigelow ML, Schimke JM, Nair KS 2003 Effect of insulin on human skeletal muscle mitochondrial ATP production, protein synthesis, and mRNA transcripts. Proc Natl Acad Sci USA 100:7996 -8001
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 7996-8001
-
-
Stump, C.S.1
Short, K.R.2
Bigelow, M.L.3
Schimke, J.M.4
Nair, K.S.5
-
18
-
-
0027259473
-
Assessment of body composition with use of dual-energy x-ray absorptiometry: Evaluation and comparison with other methods
-
Jensen MD, Kanaley JA, Roust LR, O'Brien PC, Braun JS, Dunn WL, Wahner HW 1993 Assessment of body composition with use of dual-energy x-ray absorptiometry: evaluation and comparison with other methods. Mayo Clin Proc 68:867-873
-
(1993)
Mayo Clin Proc
, vol.68
, pp. 867-873
-
-
Jensen, M.D.1
Kanaley, J.A.2
Roust, L.R.3
O'Brien, P.C.4
Braun, J.S.5
Dunn, W.L.6
Wahner, H.W.7
-
19
-
-
0030015688
-
Evidence for a catabolic role of glucagon during an amino acid load
-
Charlton MR, Adey DB, Nair KS 1996 Evidence for a catabolic role of glucagon during an amino acid load. J Clin Invest 98:90-99
-
(1996)
J Clin Invest
, vol.98
, pp. 90-99
-
-
Charlton, M.R.1
Adey, D.B.2
Nair, K.S.3
-
20
-
-
0026443847
-
Heated dorsal hand vein sampling for metabolic studies: A reappraisal
-
Copeland KC, Kenney FA, Nair KS 1992 Heated dorsal hand vein sampling for metabolic studies: a reappraisal. Am J Physiol 263: E1010-E1014
-
(1992)
Am J Physiol
, vol.263
-
-
Copeland, K.C.1
Kenney, F.A.2
Nair, K.S.3
-
21
-
-
0029073033
-
Protein dynamics in whole body and in splanchnic and leg tissues in type I diabetic patients
-
Nair KS, Ford GC, Ekberg K, Fernqvist-Forbes E, Wahren J 1995 Protein dynamics in whole body and in splanchnic and leg tissues in type I diabetic patients. J Clin Invest 95:2926-2937
-
(1995)
J Clin Invest
, vol.95
, pp. 2926-2937
-
-
Nair, K.S.1
Ford, G.C.2
Ekberg, K.3
Fernqvist-Forbes, E.4
Wahren, J.5
-
22
-
-
0025238604
-
A sensitive method for measuring ATP-formation in rat muscle mitochondria
-
Wibom R, Lundin A, Hultman E 1990 A sensitive method for measuring ATP-formation in rat muscle mitochondria. Scand J Clin Lab Invest 50:143-152
-
(1990)
Scand J Clin Lab Invest
, vol.50
, pp. 143-152
-
-
Wibom, R.1
Lundin, A.2
Hultman, E.3
-
23
-
-
0035016557
-
T(3) increases mitochondrial ATP production in oxidative muscle despite increased expression of UCP2 and -3
-
Short KR, Nygren J, Barazzoni R, Levine J, Nair KS 2001 T(3) increases mitochondrial ATP production in oxidative muscle despite increased expression of UCP2 and -3. Am J Physiol Endocrinol Metab 280:E761-E769
-
(2001)
Am J Physiol Endocrinol Metab
, vol.280
-
-
Short, K.R.1
Nygren, J.2
Barazzoni, R.3
Levine, J.4
Nair, K.S.5
-
24
-
-
0028920308
-
Overnight branched-chain amino acid infusion causes sustained suppression of muscle proteolysis
-
Louard RJ, Barrett EJ, Gelfand RA 1995 Overnight branched-chain amino acid infusion causes sustained suppression of muscle proteolysis. Metabolism 44:424-429
-
(1995)
Metabolism
, vol.44
, pp. 424-429
-
-
Louard, R.J.1
Barrett, E.J.2
Gelfand, R.A.3
-
25
-
-
0025201970
-
Effect of infused branched chain amino acids on muscle and whole-body amino acid metabolism in man
-
Louard RJ, Barrett EJ, Gelfand RA 1990 Effect of infused branched chain amino acids on muscle and whole-body amino acid metabolism in man. Clin Sci (Lond) 79:457-466
-
(1990)
Clin Sci (Lond)
, vol.79
, pp. 457-466
-
-
Louard, R.J.1
Barrett, E.J.2
Gelfand, R.A.3
-
26
-
-
35748979445
-
Effect of insulin deprivation on muscle mitochondrial ATP production and gene transcript levels in type 1 diabetic subjects
-
Karakelides H, Asmann YW, Bigelow ML, Short KR, Dhatariya K, Coenen-Schimke J, Kahl J, Mukhopadhyay D, Nair KS 2007 Effect of insulin deprivation on muscle mitochondrial ATP production and gene transcript levels in type 1 diabetic subjects. Diabetes 56:2683-2689
-
(2007)
Diabetes
, vol.56
, pp. 2683-2689
-
-
Karakelides, H.1
Asmann, Y.W.2
Bigelow, M.L.3
Short, K.R.4
Dhatariya, K.5
Coenen-Schimke, J.6
Kahl, J.7
Mukhopadhyay, D.8
Nair, K.S.9
-
27
-
-
68449094247
-
Supraphysiological hyperinsulinaemia is necessary to stimulate skeletal muscle protein anabolism in older adults: Evidence of a true age-related insulin resistance of muscle protein metabolism
-
Fujita S, Glynn EL, Timmerman KL, Rasmussen BB, Volpi E 2009 Supraphysiological hyperinsulinaemia is necessary to stimulate skeletal muscle protein anabolism in older adults: evidence of a true age-related insulin resistance of muscle protein metabolism. Diabetologia 52:1889-1898
-
(2009)
Diabetologia
, vol.52
, pp. 1889-1898
-
-
Fujita, S.1
Glynn, E.L.2
Timmerman, K.L.3
Rasmussen, B.B.4
Volpi, E.5
-
28
-
-
2342569715
-
Mitochondrial and sarcoplasmic proteins, but not myosin heavy chain, are sensitive to leucine supplementation in old rat skeletal muscle
-
Guillet C, Zangarelli A, Mishellany A, Rousset P, Sornet C, Dardevet D, Boirie Y 2004 Mitochondrial and sarcoplasmic proteins, but not myosin heavy chain, are sensitive to leucine supplementation in old rat skeletal muscle. Exp Gerontol 39:745-751
-
(2004)
Exp Gerontol
, vol.39
, pp. 745-751
-
-
Guillet, C.1
Zangarelli, A.2
Mishellany, A.3
Rousset, P.4
Sornet, C.5
Dardevet, D.6
Boirie, Y.7
-
29
-
-
0347627139
-
mTOR-mediated regulation of translation factors by amino acids
-
Proud CG 2004 mTOR-mediated regulation of translation factors by amino acids. Biochem Biophys Res Commun 313:429-436
-
(2004)
Biochem Biophys Res Commun
, vol.313
, pp. 429-436
-
-
Proud, C.G.1
-
30
-
-
0037712737
-
Amino acids as regulators of gene expression at the level of mRNA translation
-
Jefferson LS, Kimball SR 2003 Amino acids as regulators of gene expression at the level of mRNA translation. J Nutr 133:2046S-2051S
-
(2003)
J Nutr
, vol.133
-
-
Jefferson, L.S.1
Kimball, S.R.2
-
31
-
-
55849148034
-
Quantitative protein microarrays for time-resolved measurements of protein phosphorylation
-
Korf U, Derdak S, Tresch A, Henjes F, Schumacher S, Schmidt C, Hahn B, Lehmann WD, Poustka A, Beissbarth T, Klingmüller U 2008 Quantitative protein microarrays for time-resolved measurements of protein phosphorylation. Proteomics 8:4603-4612
-
(2008)
Proteomics
, vol.8
, pp. 4603-4612
-
-
Korf, U.1
Derdak, S.2
Tresch, A.3
Henjes, F.4
Schumacher, S.5
Schmidt, C.6
Hahn, B.7
Lehmann, W.D.8
Poustka, A.9
Beissbarth, T.10
Klingmüller, U.11
-
32
-
-
4444371652
-
Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics
-
Blagoev B, Ong SE, Kratchmarova I, Mann M 2004 Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics. Nat Biotechnol 22:1139-1145
-
(2004)
Nat Biotechnol
, vol.22
, pp. 1139-1145
-
-
Blagoev, B.1
Ong, S.E.2
Kratchmarova, I.3
Mann, M.4
-
33
-
-
77449109099
-
Age, obesity, and sex effects on insulin sensitivity and skeletal muscle mitochondrial function
-
doi: 10.2337/db09-0591
-
Karakelides H, Irving BA, Short KR, O'Brien P, Nair KS 2009 Age, obesity, and sex effects on insulin sensitivity and skeletal muscle mitochondrial function. Diabetes doi: 10.2337/db09-0591
-
(2009)
Diabetes
-
-
Karakelides, H.1
Irving, B.A.2
Short, K.R.3
O'Brien, P.4
Nair, K.S.5
-
34
-
-
14644444464
-
Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle
-
Cuthbertson D, Smith K, Babraj J, Leese G, Waddell T, Atherton P, Wackerhage H, Taylor PM, Rennie MJ 2005 Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle. FASEB J 19:422-424
-
(2005)
FASEB J
, vol.19
, pp. 422-424
-
-
Cuthbertson, D.1
Smith, K.2
Babraj, J.3
Leese, G.4
Waddell, T.5
Atherton, P.6
Wackerhage, H.7
Taylor, P.M.8
Rennie, M.J.9
-
35
-
-
0015388615
-
Glucagon-stimulating activity of 20 amino acids in dogs
-
Rocha DM, Faloona GR, Unger RH 1972 Glucagon-stimulating activity of 20 amino acids in dogs. J Clin Invest 51:2346-2351
-
(1972)
J Clin Invest
, vol.51
, pp. 2346-2351
-
-
Rocha, D.M.1
Faloona, G.R.2
Unger, R.H.3
-
36
-
-
0031719716
-
Effects of branched-chain-enriched amino acid solution on insulin and glucagon secretion and blood glucose level in liver cirrhosis
-
Tabaru A, Shirohara H, Moriyama A, Otsuki M 1998 Effects of branched-chain-enriched amino acid solution on insulin and glucagon secretion and blood glucose level in liver cirrhosis. Scand J Gastroenterol 33:853-859
-
(1998)
Scand J Gastroenterol
, vol.33
, pp. 853-859
-
-
Tabaru, A.1
Shirohara, H.2
Moriyama, A.3
Otsuki, M.4
-
37
-
-
0013953978
-
Stimulation of insulin secretion by amino acids
-
Floyd Jr JC, Fajans SS, Conn JW, Knopf RF, Rull J 1966 Stimulation of insulin secretion by amino acids. J Clin Invest 45:1487-1502
-
(1966)
J Clin Invest
, vol.45
, pp. 1487-1502
-
-
Floyd Jr, J.C.1
Fajans, S.S.2
Conn, J.W.3
Knopf, R.F.4
Rull, J.5
-
38
-
-
0025097009
-
Effect of plasma amino acid replacement on glucagon and substrate responses to insulin-induced hypoglycemia in humans
-
Nair KS, Welle SL, Tito J 1990 Effect of plasma amino acid replacement on glucagon and substrate responses to insulin-induced hypoglycemia in humans. Diabetes 39:376-382
-
(1990)
Diabetes
, vol.39
, pp. 376-382
-
-
Nair, K.S.1
Welle, S.L.2
Tito, J.3
-
39
-
-
0026030629
-
Effects of intravenous infusion of 17 amino acids on the secretion of GH, glucagon, and insulin in sheep
-
Kuhara T, Ikeda S, Ohneda A, Sasaki Y 1991 Effects of intravenous infusion of 17 amino acids on the secretion of GH, glucagon, and insulin in sheep. Am J Physiol 260:E21-E26
-
(1991)
Am J Physiol
, vol.260
-
-
Kuhara, T.1
Ikeda, S.2
Ohneda, A.3
Sasaki, Y.4
-
40
-
-
0026740778
-
Effect of leucine on amino acid and glucose metabolism in humans
-
Nair KS, Matthews DE, Welle SL, Braiman T 1992 Effect of leucine on amino acid and glucose metabolism in humans. Metabolism 41: 643-648
-
(1992)
Metabolism
, vol.41
, pp. 643-648
-
-
Nair, K.S.1
Matthews, D.E.2
Welle, S.L.3
Braiman, T.4
|