Error-prone translesion replication of damaged DNA suppresses skin carcinogenesis by controlling inflammatory hyperplasia

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 51, 2009, Pages 21836-21841

  Tsaalbi Shtylik, Anastasia ^a   Verspuy, Johan W A ^a   Jansen, Jacob G ^a   Rebel, Heggert ^a   Carlée, Leone M ^a   Van Der Valk, Martin A ^b   Jonkers, Jos ^b   De Gruijl, Frank R ^a   De Wind, Niels ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

DNA translesion synthesis; Interleukin 6; Skin cancer; Tumor initiation; Tumor promotion

Indexed keywords

CYTOKINE; DNA; INTERLEUKIN 6; PROTEIN P53;

ACANTHOSIS; ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; DNA SYNTHESIS; EPIDERMIS; EXCISION REPAIR; FEMALE; GENE; GENOME; GENOMIC INSTABILITY; HYPERPLASIA; INFLAMMATION; MALE; MOUSE; MUTAGENESIS; MUTATIONAL ANALYSIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REV1 GENE; SENESCENCE; SKIN CANCER; SKIN CARCINOGENESIS; TRANSLESION SYNTHESIS; ULTRAVIOLET RADIATION;

ALLELES; ANIMALS; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; INTERLEUKIN-6; MICE; MODELS, ANIMAL; NEOPLASMS, RADIATION-INDUCED; SKIN NEOPLASMS; ULTRAVIOLET RAYS;

MUS;

EID: 76049128453     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0909507106     Document Type: Article

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