Suprabasal expression of human amphiregulin in the epidermis of transgenic mice induces a severe, early-onset, psoriasis-like skin pathology: Expression of amphiregulin in the basal epidermis is also associated with synovitis

Experimental Dermatology

Volumn 13, Issue 6, 2004, Pages 347-356

  Cook, Paul W ^a,d   Brown, Jeffrey R ^a   Cornell, Kenneth A ^b   Pittelkow, Mark R ^c  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b PORTLAND VA MEDICAL CENTER   (United States)

^c MAYO CLINIC   (United States)

^d Cascade Biologics Inc   (United States)

Author keywords

Amphiregulin; Psoriasis; Psoriatic arthritis; Skin; T cell; Transgenic

Indexed keywords

AMPHIREGULIN; CD3 ANTIGEN; INVOLUCRIN;

ACANTHOSIS; ALOPECIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; ENHANCER REGION; EPIDERMIS; ERYTHEMA; GENE EXPRESSION; GENE OVEREXPRESSION; HISTOPATHOLOGY; HYPERKERATOSIS; IMMUNITY; KNEE; LIFESPAN; MOUSE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PAPILLOMA; PARAKERATOSIS; PROMOTER REGION; PROTEIN EXPRESSION; PSORIASIS; PSORIATIC ARTHRITIS; SKIN BLOOD FLOW; SKIN BLOOD VESSEL; SKIN DISEASE; SKIN INFILTRATE; SYNOVITIS; SYNOVIUM; T LYMPHOCYTE; TRANSGENIC MOUSE;

AGE OF ONSET; AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD3; EPIDERMIS; GLYCOPROTEINS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; KERATIN-14; KERATINS; KNEE JOINT; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); PSORIASIS; SEVERITY OF ILLNESS INDEX; SYNOVITIS; T-LYMPHOCYTES;

EID: 3042845742     PISSN: 09066705     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0906-6705.2004.00183.x     Document Type: Article

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