Different nitrosative-induced microtubular modifications and testosterone neuroprotective effects on high-D-glucose-exposed neuroblastoma and glioma cells

Neuroendocrinology Letters

Volumn 30, Issue 4, 2009, Pages 515-524

  Gadau, Sergio ^a   Lepore, Gianluca ^a   Zedda, Marco ^a   Mura, Arcadia ^a   Farina, Vittorio ^a  

^a UNIVERSITY OF SASSARI   (Italy)

Author keywords

3 Nitro L tyrosine; D glucose; Neuroblastoma and glioma cell lines; Neuroprotection; Testosterone; Tubulin

Indexed keywords

3 NITROTYROSINE; CATALASE; GLUCOSE; TESTOSTERONE;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL GROWTH; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; GLIOMA CELL; GROWTH RATE; MICROTUBULE; MOUSE; NEUROBLASTOMA CELL; NEUROPROTECTION; NITROSATION; NONHUMAN; OXIDATIVE STRESS; RAT; WESTERN BLOTTING;

EID: 76049085862     PISSN: 0172780X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (59)

1. Aebi H (1984). Catalase in vitro. Methods Enzymol. 105: 121-126.
2. Acarin L, Peluffo H, Barbeito L, Castellano B, Gonzalez B (2005). Astroglial nitration after postnatal excitotoxic damage: correlation with nitric oxide sources, cytoskeletal, apoptotic and anti-oxidant proteins. J Neurotrauma. 22: 189-200.
3. Ahlbom E, Prins GS, Ceccatelli S (2001). Testosterone protects cerebellar granule cells from oxidative stress-induced cell death through a receptor mediated mechanism. Brain Res. 892: 255-262.
4. Allen DA, Yaqoob MM, Harwood SM (2005). Mechanisms of high glucose-induced apoptosis and its relationship to diabetic complications. J Nutr Biochem. 16: 705-713.
5. Andersen JK (2004). Oxidative stress in neurodegeneration: cause or consequence? Nat Med. 10: 18-25.
6. Blanchard-Fillion B, Prou D, Polydoro M., Spielberg D, Tsika E, Wang Z, et al. (2006). Metabolism of 3-nitrotyrosine induces apoptotic death in dopaminergic cells. J. Neurosci. 26: 6124-6130.
7. Bolaños JP, Delgado-Esteban M, Herrero-Mendez A, Fernandez-Fernandez S, Almeida A (2008). Regulation of glycolysis and pentose-phosphate pathway by nitric oxide: impact on neuronal survival. Biochim Biophys Acta. 1777: 789-793.
8. Bolaños JP, Heales SJ, Land JM, Clark JB (1995). Effect of peroxynitrite on the mitochondrial respiratory chain: differential susceptibility of neurones and astrocytes in primary culture. J Neurochem. 64: 1965-1972.
9. Butler R, Leigh PN, Gallo JM (2001 ). Androgen-induced up-regulation of tubulin isoforms in neuroblastoma cells. J Neurochem. 78: 854-861.
10. Chance B, Sies H, Boveris A (1979). Hydroperoxide metabolism in mammalian organs. Physiol Rev. 59: 527-605.
11. Chang W, Webster DR, Salam AA, Gruber D, Prasad A, Eiserich JP, et al. (2002). Alteration of the C-terminal amino acid of tubulin specifically inhibits myogenic differentiation. J Biol Chem. 277: 30690-30698.
12. Cheng C, Zochodne DW (2003). Sensory neurons with activated caspase-3 survive long-term experimental diabetes. Diabetes. 52: 2363-2371.
13. Chisu V, Manca P, Lepore G, Gadau S, Zedda M, Farina V (2006). Testosterone induces neuroprotection from oxidative stress. Effects on catalase activity and 3-nitro-L-tyrosine incorporation into alpha-tubulin in a mouse neuroblastoma cell line. Arch Ital Biol. 144: 63-73.
14. Coers S, Tanzer L, Jones KJ (2002). Testosterone treatment attenuates the effects of facial nerve transection on glial fibrillary acidic protein (GFAP) levels in the hamster facial motor nucleus. Metab Brain Dis. 17: 55-63.
15. Delaney CL, Russell JW, Cheng HL, Feldman EL (2001). Insulin-like growth factor-I and over-expression of Bcl-xL prevent glucose-mediated apoptosis in Schwann cells. J Neuropathol Exp Neurol. 60: 147-160.
16. Desagher S, Glowinski J, Premont J (1996). Astrocytes protect neurons from hydrogen peroxide toxicity. J Neurosci. 16: 2553-2562.
17. Drel VR, Pacher P, Stevens MJ, Obrosova IG (2006). Aldose reductase inhibition counteracts nitrosative stress and poly(ADP-ribose) polymerase activation in diabetic rat kidney and high-glucose-exposed human mesangial cells. Free Radic Biol Med. 40: 1454-1465.
18. Dringen R (2000). Metabolism and functions of glutathione in brain. Prog Neurobiol. 62: 649-671.
19. Dringen R, Pawlowski PG, Hirrlinger J (2005). Peroxide detoxification by brain cells. J Neurosci Res. 79: 157-165.
20. Eaker EY, Angelastro JM, Purich DL, Sninsky CA (1991). Evidence against impaired brain microtubule protein polymerization at high glucose concentrations or during diabetes mellitus. J Neurochem. 56: 2087-2093.
21. Eiserich JP, Estevez AG, Bamberg TV, Ye YZ, Chumley PH, Beckman JS, et al. (1999). Microtubule dysfunction by posttranslational nitrotyrosination of alpha-tubulin: a nitric oxide-dependent mechanism of cellular injury. Proc Natl Acad Sci USA. 96: 6365-6370.
22. Emerit J, Edeas M, Bricaire F (2004). Neurodegenerative diseases and oxidative stress. Biom Pharm. 58: 39-46.
23. Erck C, Peris L, Andrieux A, Meissirel C, Gruber AD, Vernet M, et al. (2005). A vital role of tubulin-tyrosine-ligase for neuronal organization. Proc Natl Acad Sci USA. 102: 7853-7858.
24. Fukushima N, Furuta D, Hidaka Y, Moriyama R, Tsujiuchi T (2009). Post-translational modifications of tubulin in the nervous system. J Neurochem. 109: 683-693.
25. Gadau S, Lepore G, Zedda M, Manca P, Chisu V, Farina V (2008). D-glucose induces microtubular changes in C1300 neuroblastoma cell line through the incorporation of 3-nitro-L-tyrosine into tubulin. Arch Ital Biol. 146: 107-117.
26. García-Ovejero D, Veiga S, García-Segura LM, Doncarlos LL (2002). Glial expression of estrogen and androgen receptors after rat brain injury. J Comp Neurol. 450: 256-271.
27. Guillod-Maximin E, Lorsignol A, Alquier T, Pénicaud L (2004). Acute intracarotid glucose injection towards the brain induces specific c-fos activation in hypothalamic nuclei: involvement of astrocytes in cerebral glucose-sensing in rats. J Neuroendocrinol. 16: 464-471.
28. Halliwell B (2006). Oxidative stress and neurodegeneration: where are we now? J Histochem. 97: 1634-1658.
29. Halliwell B (1992). Reactive oxygen species and the central nervous system. J Neurochem. 59: 1609-1623
30. Halliwell B (2001). Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment. Drugs Aging. 18: 685-716.
31. Hammond J, Le Q, Goodyer C, Gelfand M, Trifiro M, LeBlanc A (2001). Testosterone-mediated neuroprotection through the androgen receptor in human primary neurons. J Neurochem. 77: 1319-1326.
32. Hertz L, Kala G (2007). Energy metabolism in brain cells: effects of elevated ammonia concentrations. Metab Brain Dis. 22: 199-218.
33. Hinshaw DB, Miller MT, Omann GM Beals TF, Hyslop PA (1993). A cellular model of oxidant-mediated neuronal injury. Brain Res. 615: 13-26.
34. Hollensworth SB, Shen CC, Sim JE, Spitz DR, Wilson GL, LeDoux SP (2000). Glial cell specific responses to menadione-induced oxidative stress. Free Rad Biol Med. 28: 1161-1174.
35. Khanna P, Nehru B (2007). Antioxidant enzymatic system in neuronal and glial cells enriched fractions of rat brain after aluminum exposure. Cell Mol Neurobiol. 27: 959-969.
36. Kurosinski P, Gotz J (2002). Glial cells under physiologic and pathologic conditions. Arch Neurol. 59: 1524-1528.
37. Makar TK, Nedergaard M, Preuss A, Gelbard AS, Perumal AS, Cooper AJ (1994). Vitamin E, ascorbate, glutathione, glutathione disulfide, and enzymes of glutathione metabolism in cultures of chick astrocytes and neurons: evidence that astrocytes play an important role in antioxidative processes in the brain. J Neurochem. 62: 45-53.
38. Marcos S, Moreau J, Backer S, Job D, Andrieux A, Bloch-Gallego E (2009). Tubulin tyrosination is required for the proper organization and pathfinding of the growth cone. PLoS One. 4: 5405.
39. Maritim AC, Sanders RA, Watkins JB (2003). Diabetes, oxidative stress and antioxidants: a review. J Biochem Mol Toxicol. 17: 24-38.
40. McCall AL (2004). Cerebral glucose metabolism in diabetes mellitus. Eur J Pharmacol. 490: 147-158.
41. McLean WG, Pekiner C, Cullum NA, Casson IF (1992). Posttranslational modifications of nerve cytoskeletal proteins in experimental diabetes. Mol Neurobiol. 6: 225-237.
42. Melcangi RC, Garcia-Segura LM, Mensah-Nyagan AG (2008). Neuroactive steroids: state of the art and new perspectives. Cell Mol Life Sci. 65: 777-797.
43. Mihm MJ, Schanbacher BL, Wallace BL, Wallace LJ, Uretsky, NJ, Bauer JA (2001). Free 3-nitrotyrosine causes striatal neurodegeneration in vivo. J Neurosci. 21: 1-5
44. Morris JA, Jordan CL, Breedlove SM (2004). Sexual differentiation of the vertebrate nervous system. Nat Neurosci. 7: 1034-1039.
45. Obrosova IG, Mabley JG, Zsengellér Z, Charniauskaya T, Abatan Ol, Groves JT et al. (2005). Role for nitrosative stress in diabetic neuropathy: evidence from studies with a peroxynitrite decomposition catalyst. FASEB J. 19: 401-403.
46. Pacher P, Obrosova IG, Mabley JG, Szabo C (2005). Role of nitrosative stress and peroxynitrite in the pathogenesis of diabetic complications. Emerging new therapeutical strategies. Curr Med Chem. 12: 267-275.
47. Peluffo H, Shacka JJ, Ricart K, Bisig CG, Martinez-Palma L, Pritsch O et al. (2004). Induction of motor neuron apoptosis by free 3-nitro-L-tyrosine. J Neurochem. 89: 602-612.
48. Phung, AD, Soucek, K, Kubala, L, Harper, RW, Chloe Bulinski, J, Eiserich, JP (2006). Posttranslational nitrotyrosination of alpha-tubulin induces cell cycle arrest and inhibits proliferation of vascular smooth muscle cells. Eur J Cell Biol. 85: 1241-1252.
49. Pike CJ (2001). Testosterone attenuates beta-amyloid toxicity in cultured hippocampal neurons. Brain Res. 919: 160-165.
50. Ramsden M, Shin TM, Pike CJ (2003). Androgens modulate neuronal vulnerability to kainate lesion. Neuroscience. 122: 573-578.
51. Russell JW, Berent-Spillson A, Vincent AM, Freimann CL, Sullivan KA, Feldman EL (2008). Oxidative injury and neuropathy in diabetes and impaired glucose tolerance. Neurobiol Dis. 30: 420-429.
52. Sayre LM, Perry G, Smith MA (2008). Oxidative stress and neurotoxicity. Chem Res Toxicol. 21: 172-188.
53. Schmidt AJ, Krieg JC, Vedder H (2005). Effects of steroid hormones on catalase activity in neuronal and glial cell systems. Eur Neuropsychopharmacol. 15: 177-183.
54. Sugimoto K, Yasujima M, Yagihashi S (2008). Role of advanced glycation end products in diabetic neuropathy. Curr Pharm Des. 14: 953-961.
55. Tanzer L, Jones KJ (2004). Neurotherapeutic action of testosterone on hamster facial nerve regeneration: temporal window of effects. Horm Behav. 45: 339-344.
56. Tunez I, Feijóo M, Collado JA, Medina FJ, Peña J, Muńoz Mdel C, et al. (2007). Effect of testosterone on oxidative stress and cell damage induced by 3-nitropropionic acid in striatum of ovariectomized rats. Life Sci. 80: 1221-1227.
57. Thuraisingham RC, Nott CA, Dodd SM, Yaqoob MM (2000). Increased nitrotyrosine staining in kidneys from patients with diabetic nephropathy. Kidney Int. 57: 1968-1972.
58. Zedda M, Lepore G, Gadau S, Manca P, Farina V (2004). Morphological and functional changes induced by the amino acid analogue 3-nitrotyrosine in mouse neuroblastoma and rat glioma cell lines. Neurosci Lett. 363: 190-193.
59. Zhou FQ, Cohan CS (2004). How actin filaments and microtubules steer growth cones to their targets. J Neurobiol. 58: 84-91.