Polymorphisms of the HTR1a allele are linked to frontal brain electrical asymmetry

Biological Psychology

Volumn 83, Issue 2, 2010, Pages 153-158

  Bismark, Andrew W ^a   Moreno, Francisco A ^a   Stewart, Jennifer L ^a   Towers, David N ^b   Coan, James A ^c   Oas, Jennifer ^a   Erickson, Robert P ^a   Allen, John J B ^a  

^a UNIVERSITY OF ARIZONA   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Asymmetry; EEG; Endophenotype; Gene; HTR1a; Serotonin

Indexed keywords

SEROTONIN 1A RECEPTOR;

ADULT; ALLELE; ALPHA RHYTHM; ARTICLE; BRAIN FUNCTION; CONTROLLED STUDY; DEPRESSION; DISEASE MARKER; DISEASE SEVERITY; ELECTROENCEPHALOGRAPHY; FEMALE; FRONTAL CORTEX; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RISK ASSESSMENT; SYMPTOMATOLOGY;

ADOLESCENT; ADULT; ALLELES; DEPRESSIVE DISORDER; FEMALE; FRONTAL LOBE; GENOTYPE; HUMANS; MALE; POLYMORPHISM, GENETIC; RECEPTOR, SEROTONIN, 5-HT1A; YOUNG ADULT;

EID: 75949129620     PISSN: 03010511     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsycho.2009.12.002     Document Type: Article

References (59)

1. Accortt E.E., Allen J.J. Frontal EEG asymmetry and premenstrual dysphoric symptomatology. Journal of Abnormal Psychology 2006, 115(1):179-184.
2. Accortt, E.E., Stewart, J.L., Coan, J.A., Manber, R., Allen, J.J.B., under review. Prefrontal brain asymmetry and risk for pre-menstrual dysphoric disorder.
3. Albert P.R., Lemonde S. 5-HT1A receptors, gene repression, and depression: guilt by association. Neuroscientist. 2004, 10(6):575-593.
4. Allen J.J., Iacono W.G., Depue R.A., Arbisi P. Regional electroencephalographic asymmetries in bipolar seasonal affective disorder before and after exposure to bright light. Biological Psychiatry 1993, 33(8-9):642-646.
5. Allen J.J., McKnight K.M., Moreno F.A., Demaree H.A., Delgado P.L. Alteration of frontal EEG asymmetry during tryptophan depletion predicts future depression. Journal of Affective Disorder 2009, 115(1-2):189-195.
6. Allen J.J., Urry H.L., Hitt S.K., Coan J.A. The stability of resting frontal electroencephalographic asymmetry in depression. Psychophysiology 2004, 41(2):269-280.
7. Allen J.J.B., Coan J.A., Nazarian M. Issues and assumptions on the road from raw signals to metrics of frontal EEG asymmetry in emotion. Biological Psychology 2004, 67:183-218.
8. Anokhin A.P., Heath A.C., Myers E. Genetic and environmental influences on frontal EEG asymmetry: a twin study. Biological Psychology 2006, 71(3):289-295.
9. Arias B., Catalan R., Gasto C., Gutierrez B., Fananas L. Evidence for a combined genetic effect of the 5-HT(1A) receptor and serotonin transporter genes in the clinical outcome of major depressive patients treated with citalopram. Journal of Psychopharmacology 2005, 19(2):166-172.
10. Bierut L., Heath J., Bucholz A., Dinwiddie K., Madden S., Statham P., Dunne D., MArtin M.N. Major depressive disorder in a community-based twin sample: are there different genetic and environmental contributions for men and women?. Archives of General Psychiatry 1999, 56:557-563.
11. Brown S.M., Hariri A.R. Neuroimaging studies of serotonin gene polymorphisms: exploring the interplay of genes, brain, and behavior. Cognitve, Affective and Behavioral Neurosciences 2006, 6(1):44-52.
12. Bruder G.E., Stewart J.W., Tenke C.E., McGrath P.J., Leite P., Bhattacharya N., et al. Electroencephalographic and perceptual asymmetry differences between responders and nonresponders to an SSRI antidepressant. Biological Psychiatry 2001, 49(5):416-425.
13. Bruder G.E., Fong R., Tenke C.E., Leite P., Towey J.P., Stewart J.E. Regional brain asymmetries in major depression with or without an anxiety disorder: a quantitative electroencephalographic study. Biological Psychiatry 1997, 41:939-948.
14. Buss K.A., Schumacher J.R.M., Dolski I., Kalin N.H., Goldsmith H., Davidson R.J. Right frontal brain activity, cortisol, and withdrawal behavior in 6-month-old infants. Behavioral Neuroscience 2003, 117:11-20.
15. Cardon L.R., Bell J.I. Association study designs for complex diseases. Nature Reviews Genetics 2001, 2(2):91-99.
16. Caspi A., Sugden K., Moffitt T.E., Taylor A., Craig I.W., Harrington H., et al. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 2003, 301(5631):386-389.
17. Chapman J.P., Chapman L.J. Handedness of hypothetically psychosis-prone subjects. Journal of Abnormal Psychology 1987, 96(2):89-93.
18. Clark L.A., Watson D. Tripartite model of anxiety and depression: psychometric evidence and taxonometric implications. Journal of Abnormal Psychology 1991, 100:316-336.
19. Coan J.A., Allen J.J. Frontal EEG asymmetry as a moderator and mediator of emotion. Biological Psychology 2004, 67(1-2):7-49.
20. Coan, J.A., Allen, J.J.B., Malone, S.M., Iacono, W.G., 2009. Prefrontal asymmetry and negative emotionality: evidence of shared genetic influence. Behavior Genetics.
21. Dawson G., Frey K., Panagiotides H., Osterling J., Hessl D. Infants of depressed mothers exhibit atypical frontal brain activity: a replication and extension of previous findings. Journal of Child Psychology and Psychiatry 1997, 38(2):179-186.
22. Davidson R.J., Marshall J.R., Tomarken A.J., Henriques J.B. While a phobic waits: regional brain electrical and autonomic activity in social phobics during anticipation of public speaking. Biological Psychiatry 2000, 47(2):85-95.
23. Fink M., Wadsak W., Savli M., Stein P., Moser U., Hahn A., et al. Lateralization of the serotonin-1A receptor distribution in language areas revealed by PET. Neuroimage 2009, 45(2):598-605.
24. First M.G.S.R.L., Gibbon M., Williams J.B. Structured Clinical Interview for DSM-IV Axis I Disorders-Clinical Version. Administration Booklet 1997, Beiometrics Research Department, New York, NY.
25. Fox N.A., Rubin K.H., Calkins S.D., Marshall T.R., Coplan R.J., Porges S.W., Long J.M., Stewart S. Frontal activation asymmetry and social competence at four years of age. Child Development 1995, 66(6):1770-1784.
26. Fox N.A., Henderson H.A., Rubin K.H., Calkins S.D., Schmidt L.A. Continuity and discontinuity of behavioral inhibition and exuberance: Psychophysiological and behavioral influences across the first four years of life. Child Development 2001, 72:1-21.
27. Frisch A., Postilnick D., Rockah R., Michaelovsky E., Postilnick S., Birman E., et al. Association of unipolar major depressive disorder with genes of the serotonergic and dopaminergic pathways. Molecular Psychiatry 1999, 4(4):389-392.
28. Gao Y., Tuvblad C., Raine A., Lozano D.I., Baker L.A. Genetic and environmental influences on frontal EEG asymmetry and alpha power in 9-10-year-old twins. Psychophysiology 2009, 46(4):787-796.
29. Glatt C.E., Tampilic M., Christie C., DeYoung J., Freimer N.B. Re-screening serotonin receptors for genetic variants identifies population and molecular genetic complexity. American Journal of Medical Genetics Part B Neuropsychiatric Genetics 2004, 124B(1):92-100.
30. Gotlib I.H.R.C., et al. Frontal EEG alpha asymmetry, depression and cognitive functioning. Cognition and Emotion 1998, 12(3):449-478.
31. Gottesman I.I., Gould T.D. The endophenotype concept in psychiatry: etymology and strategic intentions. American Journal of Psychiatry 2003, 160(4):636-645.
32. Henriques J.B., Davidson R.J. Regional brain electrical asymmetries discriminate between previously depressed and healthy control subjects. Journal of Abnormal Psychology 1990, 99(1):22-31.
33. Henriques J.B., Davidson R.J. Left frontal hypoactivation in depression. Journal of Abnormal Psychology 1991, 100(4):535-545.
34. Iacono W.G. Identifying psychophysiological risk for psychopathology: examples from substance abuse and schizophrenia research. Psychophysiology 1998, 35(6):621-637.
35. Jones N.A., Field T., Davalos M., Pickens J. EEG stability in infants/children of depressed mothers. Child Psychiatry Human Development 1997, 28(2):59-70.
36. Kato T. Molecular genetics of bipolar disorder and depression. Psychiatry and Cliniacl Neurosciences 2007, 61(1):3-19.
37. Kayser J., Tenke C.E. Principal components analysis of Laplacian waveforms as a generic method for identifying ERP generator patterns: II. Adequacy of low-density estimates. Clinical Neurophysiology 2006, 117(2):369-380.
38. Kendler K., Prescott C. A population-based twin study of lifetime major depression in men and women. Archives of General Psychiatry 1999, 56:39-44.
39. Le Francois B., Czesak M., Steubl D., Albert P.R. Transcriptional regulation at a HTR1A polymorphism associated with mental illness. Neuropharmacology 2008, 55(6):977-985.
40. Lesch K.P. Serotonergic gene expression and depression: implications for developing novel antidepressants. Journal of Affective Disorder 2001, 62(1-2):57-76.
41. Mathersul D., Williams L.M., Hopkinson P.J., Kemp A.H. Investigating models of affect: relationships among EEG alpha asymmetry, depression, and anxiety. Emotion 2008, 8:560-572.
42. McGue M., Christiansan K. The heritability of depression symptoms in elderly Danish twins: occasion-specific versus general effects. Behavior Genetics 2003, 33(2):83-93.
43. Nitschke J.B., Heller W., Palmieri P.A., Miller G.A. Contrasting patterns of brain activity in anxious apprehension and anxious arousal. Psychophysiology 1999, 36(5):628-637.
44. Ogilvie A.D., Battersby S., Bubb V.J., Fink G., Harmar A.J., Goodwim G.M., et al. Polymorphism in serotonin transporter gene associated with susceptibility to major depression. Lancet 1996, 347(9003):731-733.
45. Perrin F., Bertrand O., Giard M.H., Pernier J. Precautions in topographic mapping and in evoked potential map reading. Journal of Clinical Neurophysiology 1990, 7(4):498-506.
46. Perrin F., Pernier J., Bertrand O., Echallier J.F. Spherical splines for scalp potential and current density mapping. Electroencephalography & Clinical Neurophysiology 1989, 72(2):184-187.
47. Reid S.A., Duke L.M., Allen J.J. Resting frontal electroencephalographic asymmetry in depression: inconsistencies suggest the need to identify mediating factors. Psychophysiology 1998, 35(4):389-404.
48. Risch N., Herrell R., LEhner T., Liang K.Y., Eaves L., Hoh J., et al. Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis. JAMA: The Journal of the American Medical Association 2009, 301(23):2462-2471.
49. Santarelli L., Saxe M., Gross C., Surget A., Battaglia F., Dulawa S., et al. Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science 2003, 301(5634):805-809.
50. Schmidt L.A., Fox N.A. Patterns of cortical electrophysiology and autonomic activity in adults' shyness and sociability. Biological Psychology 1994, 38(2-3):183-198.
51. Shively C.A., Friedman D.P., Gage H.D., Bounds M.C., Brown-Proctor C., Blair J.B., et al. Behavioral depression and positron emission tomography-determined serotonin 1A receptor binding potential in cynomolgus monkeys. Archives of General Psychiatry 2006, 63(4):396-403.
52. Smit D.J., Posthuma D., Boomsma D.I., De Geus E.J. The relation between frontal EEG asymmetry and the risk for anxiety and depression. Biological Psychology 2007, 74(1):26-33.
53. Stewart, J.L., Bismark, A.W., Towers, D.N., Coan, J.A., Allen, J.J.B., under review. Resting frontal EEG asymmetry as an endophenotype for depression risk: sex-specific patterns of frontal brain asymmetry.
54. Stewart J.L., Levin-Silton R., Sass S.M., Heller W., Miller G.A. Anger style, psychopathology, and regional brain activity. Emotion 2008, 8:701-713.
55. Tomarken A.J., Dichter G.S., Garber J., Simien C. Resting frontal brain activity: linkages to maternal depression and socio-economic status among adolescents. Biological Psychology 2004, 67(1-2):77-102.
56. Watson D., O'Hara M.W., Stuart S. Hierarchical structures of affect and psychopathology and their implications for the classification of emotional disorders. Depression and Anxiety 2008, 25:282-288.
57. Watson D., Weber C., Assenheimer J.S., Clark L.A., Strauss M.E., McCormick R.A. Testing a tripartite model: I. Evaluating convergent and discriminant validity of anxiety and depression symptom scales. Journal of Abnormal Psychology 1995, 104:3-14.
58. Wiedemann G., Pauli P., Dengler W., Lutzenberger W., Birbaumer N., Buchkremer G. Frontal brain asymmetry as a biological substrate of emotions in patients with panic disorders. Archives of General Psychiatry 1999, 56(1):78-84.
59. Zhang H.Y., Ishigaki T., Tani K., Chen K., Shih J.C., Miyasato K., et al. Serotonin2A receptor gene polymorphism in mood disorders. Biological Psychiatry 1997, 41(7):768-773.