Microinjection of different doses of norepinephrine into the caudate putamen produces opposing effects in rats

Neuroscience Letters

Volumn 471, Issue 2, 2010, Pages 125-128

  Zhang, Guang wen ^a   Yang, Chun xiao ^a   Gao, He ren ^a   Zhang, Duo ^a   Zhang, Ying ^a   Jiao, Run sheng ^a   Zhang, Hui ^a   Liang, Yu ^b   Xu, Man ying ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b MUDANJIANG MEDICAL UNIVERSITY   (China)

Author keywords

Caudate putamen; Norepinephrine; Pain threshold of tail flick; Phentolamine

Indexed keywords

NORADRENALIN; PHENTOLAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CAUDATE NUCLEUS; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG MECHANISM; DRUG MEGADOSE; FEMALE; HYPERALGESIA; LOW DRUG DOSE; MALE; MICROINJECTION; NEUROMODULATION; NONHUMAN; PAIN; PAIN THRESHOLD; PRIORITY JOURNAL; PUTAMEN; RAT; TAIL FLICK TEST; THERMAL STIMULATION; THERMOREGULATION;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; HOT TEMPERATURE; MICROINJECTIONS; NOREPINEPHRINE; PAIN; PAIN MEASUREMENT; PAIN THRESHOLD; PHENTOLAMINE; PUTAMEN; RATS; REACTION TIME; TAIL;

EID: 75949119139     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.01.025     Document Type: Article

References (27)

1. Ali Z., Raja S.N., Wesselmann U., Fuchs P.N., Meyer R.A., and Campbell J.N. Intradermal injection of norepinephrine evokes pain in patients with sympathetically maintained pain. Pain 88 (2000) 161-168
2. 1b-adrenergic receptors entirely mediate dopamine release, locomotor response and behavioural sensitization to opiates and psychostimulants. Eur. J. Neurosci. 20 (2004) 3073-3084
3. Benarroch E.E. Descending monoaminergic pain modulation: bidirectional control and clinical relevance. Neurology 71 (2008) 217-221
4. 2-adrenoceptors in the nucleus raphe magnus in opioid analgesia and opioid abstinence-induced hyperalgesia. J. Neurosci. 23 (2003) 7950-7957
5. Chudler E.H., and Dong W.K. The role of the basal ganglia in nociception and pain. Pain 60 (1995) 3-38
6. Danzebrink R.M., and Gebhart G.F. Antinociceptive effects of intrathecal adrenoceptor agonists in a rat model of visceral nociception. J. Pharmacol. Exp. Ther. 253 (1990) 698-705
7. 6 antagonist SB-271046 on striatal and frontal cortex extracellular concentrations of noradrenaline, dopamine, 5-HT, glutamate and aspartate. Br. J. Pharmacol. 130 (2000) 23-26
8. 1b-Adrenergic receptors control locomotor and rewarding effects of psychostimulants and opiates. J. Neurosci. 22 (2002) 2873-2884
9. Eisenach J.C., DuPen S., Dubois M., Miguel R., Allin D., and The Epidural Clonidine Study Group. Epidural clonidine analgesia for intractable cancer pain. Pain 61 (1995) 391-399
10. Fuchs P.N., Meyer R.A., and Raja S.N. Heat, but not mechanical hyperalgesia, following adrenergic injections in normal human skin. Pain 90 (2001) 15-23
11. Gordh T. Epidural clonidine for treatment of postoperative pain after thoracotomy. A double-blind placebo-controlled study. Acta Anaesthesiol. Scand. 32 (1988) 702-709
12. 2 receptors in modulation of pain in humans: a review. Eur. J. Pharmacol. 500 (2004) 187-192
13. 2 adrenoceptors. Neuroscience 91 (1999) 979-990
14. 1 adrenoceptors mediate pronociception. Anesthesiology 96 (2002) 367-374
15. Mansikka H., Idänpään-Heikkilä J.J., and Pertovaara A. Different roles of alpha-2-adrenoceptors of the medulla versus the spinal cord in modulation of mustard oil-induced central hyperalgesia in rats. Eur. J. Pharmacol. 297 (1996) 19-26
16. 2-adrenoceptors of the medullary lateral reticular nucleus in spinal antinociception in rats. Brain Res. Bull. 37 (1995) 633-638
17. Ossipov M.H., and Gebhart G.H. Opioid, cholinergic and alpha-adrenergic influences on the modulation of nociception from the lateral reticular nucleus of the rat. Brain Res. 384 (1986) 282-293
18. Pellegrino L.J., Pellegrino A.S., and Cushman A.J. A Stereotaxic Atlas of the Rat Brain. 2nd edition (1979), Plenum Press, New York pp. 18-22
19. Pertovaara A. Noradrenergic pain modulation. Prog. Neurobiol. 80 (2006) 53-83
20. Reddy S.V., and Yaksh T.L. Spinal noradrenergic terminal system mediates antinociception. Brain Res. 189 (1980) 391-401
21. Sagen J., and Proudfit H.K. Evidence for pain modulation by pre- and postsynaptic noradrenergic receptors in the medulla oblongata. Brain Res. 331 (1985) 285-293
22. Schmitt H., Le Douarec J.C., and Petillot N. Antinociceptive effects of some alpha-sympathomimetic agents. Neuropharmacology 13 (1974) 289-294
23. Seong K.H., Jung R.P., Seon A.P., Sang W.C., Jeong C.L., So Y.L., Pan D.R., and Soo J.P. Noradrenaline inhibits substantia gelatinosa neurons in mice trigeminal subnucleus caudalis via α2 and β adrenoceptors. Neurosci. Lett. 411 (2007) 92-97
24. 2 agonists and antagonists in rats. J. Pharmacol. 261 (1992) 764-772
25. Wu C.P., Xiao X.S., Shi R.R., and Zou G.W. Micro-HPLC measured the biogenic amines neural media in the caudate nucleus and brainstem of rat. Colour Spectrum. 6 (1988) 165-168
26. Xie C.W., Tang J., and Han J.S. Different roles of electroanalgesia of norepinephrine in the brain and spinal cord of rats. Acta Physiolog. Sinica 35 (1983) 186-192
27. Yang J., Chen J.M., Liu W.Y., Song C.Y., Wang C.H., and Lin B.C. Arginine vasopressin in the caudate nucleus plays an antinociceptive role in the rat. J. Life Sci. 79 (2006) 2086-2090