메뉴 건너뛰기




Volumn 297, Issue 1-2, 1996, Pages 19-26

Different roles of α2-adrenoceptors of the medulla versus the spinal cord in modulation of mustard oil-induced central hyperalgesia in rats

Author keywords

Atipamezole; Central hyperalgesia; Lateral reticular nucleus of the medulla; Medetomidine; Neurogenic pain; Spinal cord; 2 Adrenoceptor

Indexed keywords

ALLYL ISOTHIOCYANATE; ALPHA 2 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; ATIPAMEZOLE; MEDETOMIDINE;

EID: 0029670885     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(95)00725-3     Document Type: Article
Times cited : (26)

References (39)
  • 1
    • 0021288912 scopus 로고
    • Endogenous pain control systems. Brainstem spinal pathways and endorphin circuitry
    • Basbaum, A.I. and H.L. Fields, 1984, Endogenous pain control systems. Brainstem spinal pathways and endorphin circuitry, Annu. Rev. Neurosci. 7, 309.
    • (1984) Annu. Rev. Neurosci. , vol.7 , pp. 309
    • Basbaum, A.I.1    Fields, H.L.2
  • 2
    • 0019352070 scopus 로고
    • The nucleus reticularis lateralis: A region highly sensitive to clonidine
    • Bousquet, P., J. Feldman, R. Bloch, J. Schwartz, 1981, The nucleus reticularis lateralis: a region highly sensitive to clonidine, Eur. J. Pharmacol. 69, 389.
    • (1981) Eur. J. Pharmacol. , vol.69 , pp. 389
    • Bousquet, P.1    Feldman, J.2    Bloch, R.3    Schwartz, J.4
  • 3
    • 0021085941 scopus 로고
    • Alpha-2 adrenergic receptors on neurons in the region of the lateral reticular nucleus of the rat
    • Cahusac, P.M.B. and R.G. Hill, 1983, Alpha-2 adrenergic receptors on neurons in the region of the lateral reticular nucleus of the rat, Neurosci. Lett. 42, 279.
    • (1983) Neurosci. Lett. , vol.42 , pp. 279
    • Cahusac, P.M.B.1    Hill, R.G.2
  • 4
    • 0026705684 scopus 로고
    • Anatomical evidence for genetic differences in the innervation of the rat spinal cord by noradrenergic locus coeruleus neurons
    • Clark, F.M. and H.K. Proudfit, 1992, Anatomical evidence for genetic differences in the innervation of the rat spinal cord by noradrenergic locus coeruleus neurons, Brain Res. 591, 44.
    • (1992) Brain Res. , vol.591 , pp. 44
    • Clark, F.M.1    Proudfit, H.K.2
  • 5
    • 0025297711 scopus 로고
    • Antinociceptive effects of intrathecal adrenoceptor agonists in a rat model of visceral nociception
    • Danzebrink, R.M. and G.F. Gebhart, 1990, Antinociceptive effects of intrathecal adrenoceptor agonists in a rat model of visceral nociception, J. Pharmacol. Exp. Ther. 253, 698.
    • (1990) J. Pharmacol. Exp. Ther. , vol.253 , pp. 698
    • Danzebrink, R.M.1    Gebhart, G.F.2
  • 6
    • 0019223751 scopus 로고
    • Pain modulation by adrenergic agents and morphine as measured by three pain tests
    • Dennis, S.G., R. Melzack, S. Gutman and F. Boucher, 1980, Pain modulation by adrenergic agents and morphine as measured by three pain tests, Life Sci. 26, 1247.
    • (1980) Life Sci. , vol.26 , pp. 1247
    • Dennis, S.G.1    Melzack, R.2    Gutman, S.3    Boucher, F.4
  • 7
    • 0026059514 scopus 로고
    • Antinociceptive properties of intrathecal dexmedetomidine in rats
    • Fisher, B., M.H. Zornow, T.L. Yaksh and B.M. Peterson, 1991, Antinociceptive properties of intrathecal dexmedetomidine in rats, Eur. J. Pharmacol. 192, 221.
    • (1991) Eur. J. Pharmacol. , vol.192 , pp. 221
    • Fisher, B.1    Zornow, M.H.2    Yaksh, T.L.3    Peterson, B.M.4
  • 8
    • 0022653916 scopus 로고
    • Characterization of inhibition of the spinal nociceptive tail-flick reflex in the rat from the medullary lateral reticular nucleus
    • Gebhart, G.F. and M.H. Ossipov, 1986, Characterization of inhibition of the spinal nociceptive tail-flick reflex in the rat from the medullary lateral reticular nucleus, J. Neurosci. 6, 701.
    • (1986) J. Neurosci. , vol.6 , pp. 701
    • Gebhart, G.F.1    Ossipov, M.H.2
  • 10
    • 0028979177 scopus 로고
    • 2-adrenoceptor agonist in the spinal dorsal horn is due to a direct spinal action and not to activation of descending inhibition
    • 2-adrenoceptor agonist in the spinal dorsal horn is due to a direct spinal action and not to activation of descending inhibition, Brain Res. Bull. 37, 581.
    • (1995) Brain Res. Bull. , vol.37 , pp. 581
    • Hämäläinen, M.M.1    Pertovaara, A.2
  • 11
    • 0025027512 scopus 로고
    • α-Adrenergic receptor agonists, but not antagonists, alter the tail-flick latency when microinjected into the rostral ventromedial medulla of the lightly anesthetized rat
    • Haws, C.M., M.M. Heinricher and H.L. Fields, 1990, α-Adrenergic receptor agonists, but not antagonists, alter the tail-flick latency when microinjected into the rostral ventromedial medulla of the lightly anesthetized rat, Brain Res. 533, 192.
    • (1990) Brain Res. , vol.533 , pp. 192
    • Haws, C.M.1    Heinricher, M.M.2    Fields, H.L.3
  • 12
    • 0022585503 scopus 로고
    • Antagonism of alpha-adrenoceptor agonist-induced antinociception in the rat
    • Hayes, A.G., M. Skingle and M.B. Tyers, 1986, Antagonism of alpha-adrenoceptor agonist-induced antinociception in the rat, Neuropharmacology 25, 397.
    • (1986) Neuropharmacology , vol.25 , pp. 397
    • Hayes, A.G.1    Skingle, M.2    Tyers, M.B.3
  • 13
    • 0026084861 scopus 로고
    • Spinal opioid analgesic effects in a model of unilateral inflammation/hyperalgesia: Possible involvement of noradrenergic mechanisms
    • Hylden, J.L.K., D.A. Thomas, M.J. Iadarola, R.L. Nahin and R. Dubner, 1991, Spinal opioid analgesic effects in a model of unilateral inflammation/hyperalgesia: possible involvement of noradrenergic mechanisms, Eur. J. Pharmacol. 194, 135.
    • (1991) Eur. J. Pharmacol. , vol.194 , pp. 135
    • Hylden, J.L.K.1    Thomas, D.A.2    Iadarola, M.J.3    Nahin, R.L.4    Dubner, R.5
  • 14
    • 0027941976 scopus 로고
    • Antinociceptive actions of dexmedetomidine and the kappa-opioid agonist U-50,488H against noxious thermal, mechanical and inflammatory stimuli
    • Idänpään-Heikkilä, J.J., E.A. Kalso and T. Seppälä, 1994, Antinociceptive actions of dexmedetomidine and the kappa-opioid agonist U-50,488H against noxious thermal, mechanical and inflammatory stimuli, J. Pharmacol. Exp. Ther. 271, 1306.
    • (1994) J. Pharmacol. Exp. Ther. , vol.271 , pp. 1306
    • Idänpään-Heikkilä, J.J.1    Kalso, E.A.2    Seppälä, T.3
  • 15
    • 0023413976 scopus 로고
    • Spinal monoaminergic receptors mediate the antinociception produced by glutamate in the medullary lateral reticular nucleus
    • Janss, A.J. and G.F. Gebhart, 1987, Spinal monoaminergic receptors mediate the antinociception produced by glutamate in the medullary lateral reticular nucleus, J. Neurosci. 7, 2862.
    • (1987) J. Neurosci. , vol.7 , pp. 2862
    • Janss, A.J.1    Gebhart, G.F.2
  • 16
    • 0026065087 scopus 로고
    • Spinal antinociception by dexmedetomidine, a highly selective alpha-2-adrenergic agonist
    • Kalso, E.A., R. Pöyhiä and P.H. Rosenberg, 1991, Spinal antinociception by dexmedetomidine, a highly selective alpha-2-adrenergic agonist, Pharmacol. Toxicol. 68, 140.
    • (1991) Pharmacol. Toxicol. , vol.68 , pp. 140
    • Kalso, E.A.1    Pöyhiä, R.2    Rosenberg, P.H.3
  • 17
    • 0027467224 scopus 로고
    • Antinociceptive effects of intrathecal administration of α-adrenoceptor antagonists and clonidine in the formalin test in the mouse
    • Kanui, T.I., A. Tjølsen, A. Lund, N. Mjellem-Joly and K. Hole, 1993, Antinociceptive effects of intrathecal administration of α-adrenoceptor antagonists and clonidine in the formalin test in the mouse, Neuropharmacology 32, 367.
    • (1993) Neuropharmacology , vol.32 , pp. 367
    • Kanui, T.I.1    Tjølsen, A.2    Lund, A.3    Mjellem-Joly, N.4    Hole, K.5
  • 18
    • 0026730401 scopus 로고
    • Potent antinociceptive effects of clonidine systemically administered in an experimental model of clinical pain, the arthritic rat
    • Kayser, V., G. Guilbaud and J.M. Besson, 1992, Potent antinociceptive effects of clonidine systemically administered in an experimental model of clinical pain, the arthritic rat, Brain Res. 593, 7.
    • (1992) Brain Res. , vol.593 , pp. 7
    • Kayser, V.1    Guilbaud, G.2    Besson, J.M.3
  • 19
    • 0026659520 scopus 로고
    • Selective blockade by yohimbine of descending spinal inhibition from lateral reticular nucleus but not from locus coeruleus in rats
    • Liu, R.-H. and Z.-Q. Zhao, 1992, Selective blockade by yohimbine of descending spinal inhibition from lateral reticular nucleus but not from locus coeruleus in rats, Neurosci. Lett. 142, 65.
    • (1992) Neurosci. Lett. , vol.142 , pp. 65
    • Liu, R.-H.1    Zhao, Z.-Q.2
  • 20
    • 0026319640 scopus 로고
    • Comparison of the behavioral and neurochemical effects of the two optical enantiomers of medetomidine, a selective alpha-2-adrenoceptor agonist
    • MacDonald, E., M. Scheinin, H. Scheinin and R. Virtanen, 1991, Comparison of the behavioral and neurochemical effects of the two optical enantiomers of medetomidine, a selective alpha-2-adrenoceptor agonist, J. Pharmacol. Exp. Ther. 259, 848.
    • (1991) J. Pharmacol. Exp. Ther. , vol.259 , pp. 848
    • MacDonald, E.1    Scheinin, M.2    Scheinin, H.3    Virtanen, R.4
  • 21
    • 0028983153 scopus 로고
    • 2-adrenergic agents on mustard oil-induced central hyperalgesia in rats
    • 2-adrenergic agents on mustard oil-induced central hyperalgesia in rats, Eur. J. Pharmacol. 281, 43.
    • (1995) Eur. J. Pharmacol. , vol.281 , pp. 43
    • Mansikka, H.1    Pertovaara, A.2
  • 22
    • 0028979179 scopus 로고
    • The role of the medullary lateral reticular nucleus in spinal antinociception in rats
    • Mansikka, H. and A. Pertovaara, 1995b, The role of the medullary lateral reticular nucleus in spinal antinociception in rats, Brain Res. Bull. 37, 633.
    • (1995) Brain Res. Bull. , vol.37 , pp. 633
    • Mansikka, H.1    Pertovaara, A.2
  • 23
    • 0022445055 scopus 로고
    • Opioids, cholinergic and α-adrenergic influences on the modulation of nociception from the lateral reticular nucleus of the rat
    • Ossipov, M.H. and G.F. Gebhart, 1986, Opioids, cholinergic and α-adrenergic influences on the modulation of nociception from the lateral reticular nucleus of the rat, Brain Res. 384, 282.
    • (1986) Brain Res. , vol.384 , pp. 282
    • Ossipov, M.H.1    Gebhart, G.F.2
  • 24
    • 0020660605 scopus 로고
    • Yohimbine both increases and decreases nociceptive thresholds in rats: Evaluation of the dose-response relationship
    • Paalzow, G.H. and L. Paalzow, 1983, Yohimbine both increases and decreases nociceptive thresholds in rats: evaluation of the dose-response relationship, Naunun-Schmiedeberg's Arch. Pharmacol., 332, 193.
    • (1983) Naunun-Schmiedeberg's Arch. Pharmacol. , vol.332 , pp. 193
    • Paalzow, G.H.1    Paalzow, L.2
  • 26
    • 0027531598 scopus 로고
    • Antinociception induced by alpha-2-adrenoceptor agonists, with special emphasis on medetomidine studies
    • Pertovaara, A., 1993, Antinociception induced by alpha-2-adrenoceptor agonists, with special emphasis on medetomidine studies, Prog. Neurobiol., 40, 691.
    • (1993) Prog. Neurobiol. , vol.40 , pp. 691
    • Pertovaara, A.1
  • 28
    • 0028177122 scopus 로고
    • 2-adrenergic antinociception from sedation following microinjection of medetomidine into the locus coeruleus in rats
    • 2-adrenergic antinociception from sedation following microinjection of medetomidine into the locus coeruleus in rats, Pain 57, 207.
    • (1994) Pain , vol.57 , pp. 207
    • Pertovaara, A.1    Hämäläinen, M.M.2    Kauppila, T.3    Mecke, E.4    Carlson, S.5
  • 29
    • 0023723395 scopus 로고
    • Pharmacologic evidence for the modulation of nociception by noradrenergic neurons
    • Proudfit, H.K., 1988, Pharmacologic evidence for the modulation of nociception by noradrenergic neurons, Prog. Brain Res. 77, 357.
    • (1988) Prog. Brain Res. , vol.77 , pp. 357
    • Proudfit, H.K.1
  • 30
    • 0022524574 scopus 로고
    • Does neurogenic inflammation alter the sensitivity of unmyelinated nociceptors in the rat?
    • Reeh, P.W., L. Kocher and S. Jung, 1986, Does neurogenic inflammation alter the sensitivity of unmyelinated nociceptors in the rat?, Brain Res. 384, 42.
    • (1986) Brain Res. , vol.384 , pp. 42
    • Reeh, P.W.1    Kocher, L.2    Jung, S.3
  • 31
    • 0022002623 scopus 로고
    • Evidence for pain modulation by pre- And postsynaptic noradrenergic receptors in the medulla oblongata
    • Sagen, J. and H.K. Proudfit, 1985, Evidence for pain modulation by pre- and postsynaptic noradrenergic receptors in the medulla oblongata, Brain Res. 331, 285.
    • (1985) Brain Res. , vol.331 , pp. 285
    • Sagen, J.1    Proudfit, H.K.2
  • 34
    • 0028354005 scopus 로고
    • Enhanced alpha-2 adrenergic controls and spinal morphine potency in inflammation
    • Stanfa, L.C. and A.H. Dickenson, 1994, Enhanced alpha-2 adrenergic controls and spinal morphine potency in inflammation, NeuroReport 5, 469.
    • (1994) NeuroReport , vol.5 , pp. 469
    • Stanfa, L.C.1    Dickenson, A.H.2
  • 35
    • 0028362571 scopus 로고
    • Descending projections from the caudal medulla oblongata to the superficial or deep dorsal horn of the rat spinal cord
    • Tavares, I. and D. Lima, 1994, Descending projections from the caudal medulla oblongata to the superficial or deep dorsal horn of the rat spinal cord, Exp. Brain Res. 99, 455.
    • (1994) Exp. Brain Res. , vol.99 , pp. 455
    • Tavares, I.1    Lima, D.2
  • 37
    • 0026620541 scopus 로고
    • The depressive effect of intrathecal clonidine on the spinal flexor reflex is enhanced after sciatic nerve section in rats
    • Xu, X.J., M.J.C. Puke and Z. Wiesenfeld-Hallin, 1992, The depressive effect of intrathecal clonidine on the spinal flexor reflex is enhanced after sciatic nerve section in rats, Pain 51, 145.
    • (1992) Pain , vol.51 , pp. 145
    • Xu, X.J.1    Puke, M.J.C.2    Wiesenfeld-Hallin, Z.3
  • 38
    • 0021966740 scopus 로고
    • Pharmacology of spinal adrenergic systems which modulate nociceptive processing
    • Yaksh, T.L., 1985, Pharmacology of spinal adrenergic systems which modulate nociceptive processing, Pharmacol. Biochem. Behav. 22, 845.
    • (1985) Pharmacol. Biochem. Behav. , vol.22 , pp. 845
    • Yaksh, T.L.1
  • 39
    • 0017036162 scopus 로고
    • Chronic catheterization of the spinal subarachnoid space
    • Yaksh, T.L. and T.A. Rudy, 1976, Chronic catheterization of the spinal subarachnoid space, Physiol. Behav. 17, 1031.
    • (1976) Physiol. Behav. , vol.17 , pp. 1031
    • Yaksh, T.L.1    Rudy, T.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.