메뉴 건너뛰기




Volumn 54, Issue 2, 2010, Pages 898-906

Therapy of murine pulmonary aspergillosis with antibody-alliinase conjugates and alliin

Author keywords

[No Author keywords available]

Indexed keywords

ALLICIN; ALLIIN; ALLIIN LYASE; ANTIBODY CONJUGATE; ASPERGILLUS FUMIGATUS MONOCLONAL ANTIBODY ALLIIN LYASE CONJUGATE; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

EID: 75749137693     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01267-09     Document Type: Article
Times cited : (28)

References (55)
  • 1
    • 0032715514 scopus 로고    scopus 로고
    • Antimicrobial properties of allicin from garlic
    • Ankri, S., and D. Mirelman. 1999. Antimicrobial properties of allicin from garlic. Microbes Infect. 1:125-129.
    • (1999) Microbes Infect , vol.1 , pp. 125-129
    • Ankri, S.1    Mirelman, D.2
  • 2
    • 0030765775 scopus 로고    scopus 로고
    • Allicin from garlic strongly inhibits cysteine proteinases and cytopathic effects of Entamoeba histolytica
    • Ankri, S., T. Miron, A. Rabinkov, M. Wilchek, and D. Mirelman. 1997. Allicin from garlic strongly inhibits cysteine proteinases and cytopathic effects of Entamoeba histolytica. Antimicrob. Agents Chemother. 41:2286-2288.
    • (1997) Antimicrob. Agents Chemother , vol.41 , pp. 2286-2288
    • Ankri, S.1    Miron, T.2    Rabinkov, A.3    Wilchek, M.4    Mirelman, D.5
  • 3
    • 14844286972 scopus 로고    scopus 로고
    • Apoptotic killing of B-chronic lymphocytic leukemia tumor cells by allicin generated in situ using a rituximab-alliinase conjugate
    • Arditti, F. D., A. Rabinkov, T. Miron, Y. Reisner, A. Berrebi, M. Wilchek, and D. Mirelman. 2005. Apoptotic killing of B-chronic lymphocytic leukemia tumor cells by allicin generated in situ using a rituximab-alliinase conjugate. Mol. Cancer Ther. 4:325-331.
    • (2005) Mol. Cancer Ther , vol.4 , pp. 325-331
    • Arditti, F.D.1    Rabinkov, A.2    Miron, T.3    Reisner, Y.4    Berrebi, A.5    Wilchek, M.6    Mirelman, D.7
  • 4
    • 33750711698 scopus 로고    scopus 로고
    • Antibody-directed enzyme prodrug therapy (ADEPT) for cancer
    • Bagshawe, K. D. 2006. Antibody-directed enzyme prodrug therapy (ADEPT) for cancer. Expert Rev. Anticancer Ther. 6:1421-1431.
    • (2006) Expert Rev. Anticancer Ther , vol.6 , pp. 1421-1431
    • Bagshawe, K.D.1
  • 6
    • 0037103116 scopus 로고    scopus 로고
    • A double-blind, randomized, controlled trial of amphotericin B colloidal dispersion versus amphotericin for treatment of invasive aspergillosis in immunocompromised patients
    • Bowden, R., P. Chandrasekar, M. H. White, X. Li, L. Pietrelli, M. Gurwith, J. A. van Burik, M. Laverdiere, S. Safrin, and J. R. Wingard. 2002. A double-blind, randomized, controlled trial of amphotericin B colloidal dispersion versus amphotericin for treatment of invasive aspergillosis in immunocompromised patients. Clin. Infect. Dis. 35:359-366.
    • (2002) Clin. Infect. Dis , vol.35 , pp. 359-366
    • Bowden, R.1    Chandrasekar, P.2    White, M.H.3    Li, X.4    Pietrelli, L.5    Gurwith, M.6    van Burik, J.A.7    Laverdiere, M.8    Safrin, S.9    Wingard, J.R.10
  • 7
    • 69449098249 scopus 로고    scopus 로고
    • Trends in antifungal susceptibility testing using CLSI reference and commercial methods. Expert Rev. Anti Infect
    • Cantón, E., A. Espinel-Ingroff, and J. Pemán. 2009. Trends in antifungal susceptibility testing using CLSI reference and commercial methods. Expert Rev. Anti Infect. Ther. 7:107-119.
    • (2009) Ther , vol.7 , pp. 107-119
    • Cantón, E.1    Espinel-Ingroff, A.2    Pemán, J.3
  • 8
  • 9
    • 24944440672 scopus 로고    scopus 로고
    • Monoclonal immunoglobulin G1 directed against Aspergillus fumigatus cell wall glycoprotein protects against experimental murine aspergillosis
    • Chaturvedi, A. K., A. Kavishwar, G. B. Shiva Keshava, and P. K. Shukla. 2005. Monoclonal immunoglobulin G1 directed against Aspergillus fumigatus cell wall glycoprotein protects against experimental murine aspergillosis. Clin. Diagn. Lab. Immunol. 12:1063-1068.
    • (2005) Clin. Diagn. Lab. Immunol , vol.12 , pp. 1063-1068
    • Chaturvedi, A.K.1    Kavishwar, A.2    Shiva Keshava, G.B.3    Shukla, P.K.4
  • 10
    • 0027563070 scopus 로고
    • Frequency of bronchopulmonary isolation of Aspergillus species in patients infected with human immunodeficiency virus: Pathogenic role?
    • Daleine, G., D. Salmon, J. F. Lucet, P. Longuet, O. Bouchaud, C. Chochillon, and J. Le Bras. 1993. Frequency of bronchopulmonary isolation of Aspergillus species in patients infected with human immunodeficiency virus: pathogenic role? Pathol. Biol. (Paris) 41:237-241.
    • (1993) Pathol. Biol. (Paris) , vol.41 , pp. 237-241
    • Daleine, G.1    Salmon, D.2    Lucet, J.F.3    Longuet, P.4    Bouchaud, O.5    Chochillon, C.6    Le Bras, J.7
  • 11
    • 15444378850 scopus 로고    scopus 로고
    • An overview of the antifungal properties of allicin and its breakdown products - the possibility of a safe and effective antifungal prophylactic
    • Davis, S. R. 2005. An overview of the antifungal properties of allicin and its breakdown products - the possibility of a safe and effective antifungal prophylactic. Mycoses 48:95-100.
    • (2005) Mycoses , vol.48 , pp. 95-100
    • Davis, S.R.1
  • 13
    • 33745646085 scopus 로고    scopus 로고
    • Invasive fungal infections; a review of epidemiology and management options
    • Enoch, D. A., H. A. Ludlam, and N. M. Brown. 2006. Invasive fungal infections; a review of epidemiology and management options. J. Med. Microbiol. 55:809-818.
    • (2006) J. Med. Microbiol , vol.55 , pp. 809-818
    • Enoch, D.A.1    Ludlam, H.A.2    Brown, N.M.3
  • 14
    • 0000817158 scopus 로고
    • Garlic chemistry - stability of S-(2-propenyl) 2-propene-1-sulfinothioate (allicin) in blood, solvents, and simulated physiological fluids
    • Freeman, F., and Y. Kodera. 1995. Garlic chemistry - stability of S-(2-propenyl) 2-propene-1-sulfinothioate (allicin) in blood, solvents, and simulated physiological fluids. J. Agric. Food Chem. 43:2332-2338.
    • (1995) J. Agric. Food Chem , vol.43 , pp. 2332-2338
    • Freeman, F.1    Kodera, Y.2
  • 16
    • 43549110280 scopus 로고    scopus 로고
    • Caspofungin for treatment of invasive Aspergillus infections
    • Heinz, W. J., and H. Einsele. 2008. Caspofungin for treatment of invasive Aspergillus infections. Mycoses 51:47-57.
    • (2008) Mycoses , vol.51 , pp. 47-57
    • Heinz, W.J.1    Einsele, H.2
  • 17
    • 0015850977 scopus 로고
    • Intratracheal instillation method for mouse lungs
    • Ho, W., and A. Furst. 1973. Intratracheal instillation method for mouse lungs. Oncology 27:385-393.
    • (1973) Oncology , vol.27 , pp. 385-393
    • Ho, W.1    Furst, A.2
  • 20
    • 75749129717 scopus 로고    scopus 로고
    • Koch, H. P., and L. D. Lawson (ed.). 1996. Garlic: the science and therapeutic application of Allium sativum L. and related species, 2nd ed. Williams & Wilkins, Baltimore, MD.
    • Koch, H. P., and L. D. Lawson (ed.). 1996. Garlic: the science and therapeutic application of Allium sativum L. and related species, 2nd ed. Williams & Wilkins, Baltimore, MD.
  • 21
    • 0022355089 scopus 로고
    • Purified immunotoxins that are reactive with human lymphoid cells. Monoclonal antibodies conjugated to the ribosome-inactivating proteins gelonin and the pokeweed antiviral proteins
    • Lambert, J. M., P. D. Senter, A. Yau-Young, W. A. Blattler, and V. S. Goldmacher. 1985. Purified immunotoxins that are reactive with human lymphoid cells. Monoclonal antibodies conjugated to the ribosome-inactivating proteins gelonin and the pokeweed antiviral proteins. J. Biol. Chem. 260:12035-12041.
    • (1985) J. Biol. Chem , vol.260 , pp. 12035-12041
    • Lambert, J.M.1    Senter, P.D.2    Yau-Young, A.3    Blattler, W.A.4    Goldmacher, V.S.5
  • 22
    • 0035423126 scopus 로고    scopus 로고
    • The pathology of Aspergillus fumigatus
    • Latgé, J. P. 2001. The pathology of Aspergillus fumigatus. Trends Microbiol. 9:382-389.
    • (2001) Trends Microbiol , vol.9 , pp. 382-389
    • Latgé, J.P.1
  • 23
    • 67651123296 scopus 로고    scopus 로고
    • Echinocandin activity against Aspergillus spp. and the importance of pharmacodynamics
    • Lewis, J. S. 2009. Echinocandin activity against Aspergillus spp. and the importance of pharmacodynamics. Med. Mycol. 47:S376-S381.
    • (2009) Med. Mycol , vol.47
    • Lewis, J.S.1
  • 24
    • 0344688183 scopus 로고    scopus 로고
    • Glucocorticoids and invasive fungal infections
    • Lionakis, M. S., and D. P. Kontoyiannis. 2003. Glucocorticoids and invasive fungal infections. Lancet 362:1828-1838.
    • (2003) Lancet , vol.362 , pp. 1828-1838
    • Lionakis, M.S.1    Kontoyiannis, D.P.2
  • 25
    • 34547927822 scopus 로고    scopus 로고
    • Invasive aspergillosis: Epidemiology, diagnosis and management in immunocompromised patients
    • Maschmeyer, G., A. Haas, and O. A. Cornely. 2007. Invasive aspergillosis: epidemiology, diagnosis and management in immunocompromised patients. Drugs 67:1567-1601.
    • (2007) Drugs , vol.67 , pp. 1567-1601
    • Maschmeyer, G.1    Haas, A.2    Cornely, O.A.3
  • 27
    • 2442638335 scopus 로고    scopus 로고
    • Inhibition of tumor growth by a novel approach: In situ allicin generation using targeted alliinase delivery
    • Miron, T., M. Mironchik, D. Mirelman, M. Wilchek, and A. Rabinkov. 2003. Inhibition of tumor growth by a novel approach: in situ allicin generation using targeted alliinase delivery. Mol. Cancer Ther. 2:1295-1301.
    • (2003) Mol. Cancer Ther , vol.2 , pp. 1295-1301
    • Miron, T.1    Mironchik, M.2    Mirelman, D.3    Wilchek, M.4    Rabinkov, A.5
  • 28
    • 0032534797 scopus 로고    scopus 로고
    • A spectrophotometric assay for allicin and alliinase (Alliin lyase) activity: Reaction of 2-nitro-5-thiobenzoate with thiosulfinates
    • Miron, T., A. Rabinkov, D. Mirelman, L. Weiner, and M. Wilchek. 1998. A spectrophotometric assay for allicin and alliinase (Alliin lyase) activity: reaction of 2-nitro-5-thiobenzoate with thiosulfinates. Anal. Biochem. 265: 317-325.
    • (1998) Anal. Biochem , vol.265 , pp. 317-325
    • Miron, T.1    Rabinkov, A.2    Mirelman, D.3    Weiner, L.4    Wilchek, M.5
  • 29
    • 0033973286 scopus 로고    scopus 로고
    • The mode of action of allicin: Its ready permeability through phospholipid membranes may contribute to its biological activity
    • Miron, T., A. Rabinkov, D. Mirelman, M. Wilchek, and L. Weiner. 2000. The mode of action of allicin: its ready permeability through phospholipid membranes may contribute to its biological activity. Biochim. Biophys. Acta 1463:20-30.
    • (2000) Biochim. Biophys. Acta , vol.1463 , pp. 20-30
    • Miron, T.1    Rabinkov, A.2    Mirelman, D.3    Wilchek, M.4    Weiner, L.5
  • 30
    • 33644933461 scopus 로고    scopus 로고
    • A method for continuous production of allicin using immobilized alliinase
    • Miron, T., H. SivaRaman, A. Rabinkov, D. Mirelman, and M. Wilchek. 2006. A method for continuous production of allicin using immobilized alliinase. Anal. Biochem. 351:152-154.
    • (2006) Anal. Biochem , vol.351 , pp. 152-154
    • Miron, T.1    SivaRaman, H.2    Rabinkov, A.3    Mirelman, D.4    Wilchek, M.5
  • 31
    • 62149098304 scopus 로고    scopus 로고
    • Liposomal amphotericin B: A review of its use as empirical therapy in febrile neutropenia and in the treatment of invasive fungal infections
    • Moen, M. D., K. A. Lyseng-Williamson, and L. J. Scott. 2009. Liposomal amphotericin B: a review of its use as empirical therapy in febrile neutropenia and in the treatment of invasive fungal infections. Drugs 69:361-392.
    • (2009) Drugs , vol.69 , pp. 361-392
    • Moen, M.D.1    Lyseng-Williamson, K.A.2    Scott, L.J.3
  • 32
    • 0042825353 scopus 로고    scopus 로고
    • A monoclonal antibody directed against a Candida albicans cell wall mannoprotein exerts three anti-C. albicans activities
    • Moragues, M. D., M. J. Omaetxebarria, N. Elguezabal, M. J. Sevilla, S. Conti, L. Polonelli, and J. Pontón. 2003. A monoclonal antibody directed against a Candida albicans cell wall mannoprotein exerts three anti-C. albicans activities. Infect. Immun. 71:5273-5279.
    • (2003) Infect. Immun , vol.71 , pp. 5273-5279
    • Moragues, M.D.1    Omaetxebarria, M.J.2    Elguezabal, N.3    Sevilla, M.J.4    Conti, S.5    Polonelli, L.6    Pontón, J.7
  • 33
    • 84990454730 scopus 로고
    • Fungal spores in lung and sputum
    • Mullins, J., and A. Seaton. 1978. Fungal spores in lung and sputum. Clin. Allergy 8:525-533.
    • (1978) Clin. Allergy , vol.8 , pp. 525-533
    • Mullins, J.1    Seaton, A.2
  • 34
    • 0034029267 scopus 로고    scopus 로고
    • Intratracheal administration to the lung enhances therapeutic benefit of an MBP peptide in the treatment of murine experimental autoimmune encephalomyelitis
    • Pietropaolo, M., C. D. Olson, B. S. Reiseter, M. T. Kasaian, and M. P. Happ. 2000. Intratracheal administration to the lung enhances therapeutic benefit of an MBP peptide in the treatment of murine experimental autoimmune encephalomyelitis. Clin. Immunol. 95:104-116.
    • (2000) Clin. Immunol , vol.95 , pp. 104-116
    • Pietropaolo, M.1    Olson, C.D.2    Reiseter, B.S.3    Kasaian, M.T.4    Happ, M.P.5
  • 35
    • 0001381813 scopus 로고
    • Inverse problems in polymer characterization: Direct analysis of polydispersity with proton correlation spectroscopy
    • Provencher, S. W. 1979. Inverse problems in polymer characterization: direct analysis of polydispersity with proton correlation spectroscopy. Makromol. Chem. 180:201-209.
    • (1979) Makromol. Chem , vol.180 , pp. 201-209
    • Provencher, S.W.1
  • 37
    • 0034639280 scopus 로고    scopus 로고
    • S-Allylmercaptoglutathione: The reaction product of allicin with glutathione possesses SH-modifying and antioxidant properties
    • Rabinkov, A., T. Miron, D. Mirelman, M. Wilchek, S. Glozman, E. Yavin, and L. Weiner. 2000. S-Allylmercaptoglutathione: the reaction product of allicin with glutathione possesses SH-modifying and antioxidant properties. Biochim. Biophys. Acta 1499:144-153.
    • (2000) Biochim. Biophys. Acta , vol.1499 , pp. 144-153
    • Rabinkov, A.1    Miron, T.2    Mirelman, D.3    Wilchek, M.4    Glozman, S.5    Yavin, E.6    Weiner, L.7
  • 38
    • 0028784554 scopus 로고
    • Alliinase (alliin lyase) from garlic (Alliium sativum) is glycosylated at ASN146 and forms a complex with a garlic mannose-specific lectin
    • Rabinkov, A., M. Wilchek, and D. Mirelman. 1995. Alliinase (alliin lyase) from garlic (Alliium sativum) is glycosylated at ASN146 and forms a complex with a garlic mannose-specific lectin. Glycoconj. J. 12:690-698.
    • (1995) Glycoconj. J , vol.12 , pp. 690-698
    • Rabinkov, A.1    Wilchek, M.2    Mirelman, D.3
  • 39
    • 0028503893 scopus 로고
    • Alliin lyase (Alliinase) from garlic (Allium sativum). Biochemical characterization and cDNA cloning
    • Rabinkov, A., X. Z. Zhu, G. Grafi, G. Galili, and D. Mirelman. 1994. Alliin lyase (Alliinase) from garlic (Allium sativum). Biochemical characterization and cDNA cloning. Appl. Biochem. Biotechnol. 48:149-171.
    • (1994) Appl. Biochem. Biotechnol , vol.48 , pp. 149-171
    • Rabinkov, A.1    Zhu, X.Z.2    Grafi, G.3    Galili, G.4    Mirelman, D.5
  • 40
    • 51649093093 scopus 로고    scopus 로고
    • Cell mediated immunity to fungi: A reassessment
    • Romani, L. 2008. Cell mediated immunity to fungi: a reassessment. Med. Mycol. 46:515-529.
    • (2008) Med. Mycol , vol.46 , pp. 515-529
    • Romani, L.1
  • 41
    • 40649108887 scopus 로고    scopus 로고
    • Renal impairment and amphotericin B formulations in patients with invasive fungal infections
    • Saliba, F., and B. Dupont. 2008. Renal impairment and amphotericin B formulations in patients with invasive fungal infections. Med. Mycol. 46:97-112.
    • (2008) Med. Mycol , vol.46 , pp. 97-112
    • Saliba, F.1    Dupont, B.2
  • 42
    • 0021060056 scopus 로고
    • Killing of Aspergillus spores depends on the anatomical source of the macrophage
    • Schaffner, A., H. Douglas, A. I. Braude, and C. E. Davis. 1983. Killing of Aspergillus spores depends on the anatomical source of the macrophage. Infect. Immun. 42:1109-1115.
    • (1983) Infect. Immun , vol.42 , pp. 1109-1115
    • Schaffner, A.1    Douglas, H.2    Braude, A.I.3    Davis, C.E.4
  • 43
    • 38449087458 scopus 로고    scopus 로고
    • Role of macrophages in host defense against aspergillosis and strategies for immune augmentation
    • Segal, B. H. 2007. Role of macrophages in host defense against aspergillosis and strategies for immune augmentation. Oncologist 12:7-13.
    • (2007) Oncologist , vol.12 , pp. 7-13
    • Segal, B.H.1
  • 44
    • 2442654043 scopus 로고    scopus 로고
    • Efficacy of allicin, the reactive molecule of garlic, in inhibiting Aspergillus spp. in vitro, and in a murine model of disseminated aspergillosis
    • Shadkchan, Y., E. Shemesh, D. Mirelman, T. Miron, A. Rabinkov, M. Wilchek, and N. Osherov. 2004. Efficacy of allicin, the reactive molecule of garlic, in inhibiting Aspergillus spp. in vitro, and in a murine model of disseminated aspergillosis. J. Antimicrob. Chemother. 53:832-836.
    • (2004) J. Antimicrob. Chemother , vol.53 , pp. 832-836
    • Shadkchan, Y.1    Shemesh, E.2    Mirelman, D.3    Miron, T.4    Rabinkov, A.5    Wilchek, M.6    Osherov, N.7
  • 46
    • 33846447422 scopus 로고    scopus 로고
    • Two structures of alliinase from Allium sativum L: Apo form and ternary complex with aminoacrylate reaction intermediate covalently bound to the PLP cofactor
    • Shimon, L. J., A. Rabinkov, I. Shin, T. Miron, D. Mirelman, M. Wilchek, and F. Frolow. 2007. Two structures of alliinase from Allium sativum L: apo form and ternary complex with aminoacrylate reaction intermediate covalently bound to the PLP cofactor. J. Mol. Biol. 366:611-625.
    • (2007) J. Mol. Biol , vol.366 , pp. 611-625
    • Shimon, L.J.1    Rabinkov, A.2    Shin, I.3    Miron, T.4    Mirelman, D.5    Wilchek, M.6    Frolow, F.7
  • 47
    • 20444484565 scopus 로고    scopus 로고
    • The immune response to fungal infections
    • Shoham, S., and S. M. Levitz. 2005. The immune response to fungal infections. Br. J. Haematol. 129:569-582.
    • (2005) Br. J. Haematol , vol.129 , pp. 569-582
    • Shoham, S.1    Levitz, S.M.2
  • 48
    • 12944291020 scopus 로고    scopus 로고
    • Aspergillus infections in transplant recipients
    • Singh, N., and D. L. Paterson. 2005. Aspergillus infections in transplant recipients. Clin. Microbiol. Rev. 18:44-69.
    • (2005) Clin. Microbiol. Rev , vol.18 , pp. 44-69
    • Singh, N.1    Paterson, D.L.2
  • 49
    • 24144451769 scopus 로고    scopus 로고
    • Effects of intratracheal administration of novispirin G10 on a rat model of mucoid Pseudomonas aeruginosa lung infection
    • Song, Z., H. Wu, P. Mygind, D. Raventos, C. Sonksen, H. H. Kristensen, and N. Høiby. 2005. Effects of intratracheal administration of novispirin G10 on a rat model of mucoid Pseudomonas aeruginosa lung infection. Antimicrob. Agents Chemother. 49:3868-3874.
    • (2005) Antimicrob. Agents Chemother , vol.49 , pp. 3868-3874
    • Song, Z.1    Wu, H.2    Mygind, P.3    Raventos, D.4    Sonksen, C.5    Kristensen, H.H.6    Høiby, N.7
  • 50
    • 0141956267 scopus 로고    scopus 로고
    • Review of newer antifungal and immunomodulatory strategies for invasive aspergillosis
    • Steinbach, W. J., and D. A. Stevens. 2003. Review of newer antifungal and immunomodulatory strategies for invasive aspergillosis. Clin. Infect. Dis. 37:S157-S187.
    • (2003) Clin. Infect. Dis , vol.37
    • Steinbach, W.J.1    Stevens, D.A.2
  • 51
    • 84981838512 scopus 로고
    • Allium compounds V. The synthesis of natural alliin and its three optical isomers
    • Stoll, M., and E. Seebeck. 1951. Allium compounds V. The synthesis of natural alliin and its three optical isomers. Helv. Chim. Acta 34:481-487.
    • (1951) Helv. Chim. Acta , vol.34 , pp. 481-487
    • Stoll, M.1    Seebeck, E.2
  • 54
    • 50949089497 scopus 로고    scopus 로고
    • Efficient clearance of Aspergillus fumigatus in murine lungs by an ultrashort antimicrobial lipopeptide, palmitoyl-Lys-Ala-DAla- Lys
    • Vallon-Eberhard, A., A. Makovitzki, A. Beauvais, J. P. Latge, S. Jung, and Y. Shai. 2008. Efficient clearance of Aspergillus fumigatus in murine lungs by an ultrashort antimicrobial lipopeptide, palmitoyl-Lys-Ala-DAla- Lys. Antimicrob. Agents Chemother. 52:3118-3126.
    • (2008) Antimicrob. Agents Chemother , vol.52 , pp. 3118-3126
    • Vallon-Eberhard, A.1    Makovitzki, A.2    Beauvais, A.3    Latge, J.P.4    Jung, S.5    Shai, Y.6
  • 55
    • 0038744442 scopus 로고    scopus 로고
    • Aspergillus fumigatus conidia survive and germinate in acidic organelles of A549 epithelial cells
    • Wasylnka, J. A., and M. M. Moore. 2003. Aspergillus fumigatus conidia survive and germinate in acidic organelles of A549 epithelial cells. J. Cell Sci. 116:1579-1587.
    • (2003) J. Cell Sci , vol.116 , pp. 1579-1587
    • Wasylnka, J.A.1    Moore, M.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.