메뉴 건너뛰기




Volumn 51, Issue 2, 2010, Pages 311-328

MIRD pamphlet No. 22 (Abridged): Radiobiology and dosimetry of α-particle emitters for targeted radionuclide therapy

Author keywords

particle emitters; Human particle emitter dosimetry; Targeted particle emitter therapy

Indexed keywords

ACTINIUM 225; ASTATINE 211; BISMUTH 213; IODINE 131; OXYGEN; PLACEBO; POLONIUM; RADIOISOTOPE; RADIUM 223; RITUXIMAB; UNCLASSIFIED DRUG; YTTRIUM 90;

EID: 75749110617     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.108.058651     Document Type: Review
Times cited : (373)

References (155)
  • 2
    • 0024292678 scopus 로고
    • Radioimmunotherapy with alpha-particle emitting immunoconjugates
    • Macklis RM, Kinsey BM, Kassis AI, et al. Radioimmunotherapy with alpha-particle emitting immunoconjugates. Science. 1988;240:1024-1026.
    • (1988) Science , vol.240 , pp. 1024-1026
    • Macklis, R.M.1    Kinsey, B.M.2    Kassis, A.I.3
  • 3
    • 0033848363 scopus 로고    scopus 로고
    • Astatine-211-labeled radiotherapeutics: An emerging approach to targeted alpha-particle radiotherapy
    • Zalutsky MR, Vaidyanathan G. Astatine-211-labeled radiotherapeutics: an emerging approach to targeted alpha-particle radiotherapy. Curr Pharm Des. 2000;6:1433-1455.
    • (2000) Curr Pharm Des , vol.6 , pp. 1433-1455
    • Zalutsky, M.R.1    Vaidyanathan, G.2
  • 4
    • 0035900395 scopus 로고    scopus 로고
    • Tumor therapy with targeted atomic nanogenerators
    • McDevitt MR, Ma D, Lai LT, et al. Tumor therapy with targeted atomic nanogenerators. Science. 2001;294:1537-1540.
    • (2001) Science , vol.294 , pp. 1537-1540
    • McDevitt, M.R.1    Ma, D.2    Lai, L.T.3
  • 5
    • 0031715792 scopus 로고    scopus 로고
    • Radioimmunotherapy with alpha-emitting nuclides
    • McDevitt MR, Sgouros G, Finn RD, et al. Radioimmunotherapy with alpha-emitting nuclides. Eur J Nucl Med. 1998;25:1341-1351.
    • (1998) Eur J Nucl Med , vol.25 , pp. 1341-1351
    • McDevitt, M.R.1    Sgouros, G.2    Finn, R.D.3
  • 6
    • 14844340282 scopus 로고    scopus 로고
    • The promise of targeted α-particle therapy
    • Mulford DA, Scheinberg DA, Jurcic JG. The promise of targeted α-particle therapy. J Nucl Med. 2005;46(suppl 1):199S-204S.
    • (2005) J Nucl Med , vol.46 , Issue.SUPPL. 1
    • Mulford, D.A.1    Scheinberg, D.A.2    Jurcic, J.G.3
  • 7
    • 0035115221 scopus 로고    scopus 로고
    • Antibody therapy for residual disease in acute myelogenous leukemia
    • Jurcic JG. Antibody therapy for residual disease in acute myelogenous leukemia. Crit Rev Oncol Hematol. 2001;38:37-45.
    • (2001) Crit Rev Oncol Hematol , vol.38 , pp. 37-45
    • Jurcic, J.G.1
  • 8
    • 0002951119 scopus 로고
    • Potential use of alpha-emitting radionuclides in the treatment of cancer
    • Wilbur DS. Potential use of alpha-emitting radionuclides in the treatment of cancer. Antibody Immunoconjugates Radiopharm. 1990;4:85-97.
    • (1990) Antibody Immunoconjugates Radiopharm , vol.4 , pp. 85-97
    • Wilbur, D.S.1
  • 9
    • 33750339604 scopus 로고    scopus 로고
    • Cancer stem cells and metastasis: Lethal seeds [commentary]
    • Wicha MS. Cancer stem cells and metastasis: lethal seeds [commentary]. Clin Cancer Res. 2006;12:5606-5607.
    • (2006) Clin Cancer Res , vol.12 , pp. 5606-5607
    • Wicha, M.S.1
  • 10
    • 39749083272 scopus 로고    scopus 로고
    • 213Bi: Mathematical modeling and feasibility analysis
    • 213Bi: mathematical modeling and feasibility analysis. Cancer Biother Radiopharm. 2008;23:74-81.
    • (2008) Cancer Biother Radiopharm , vol.23 , pp. 74-81
    • Sgouros, G.1    Song, H.2
  • 11
    • 0037103293 scopus 로고    scopus 로고
    • Targeted alpha particle immunotherapy for myeloid leukemia
    • Jurcic JG, Larson SM, Sgouros G, et al. Targeted alpha particle immunotherapy for myeloid leukemia. Blood. 2002;100:1233-1239.
    • (2002) Blood , vol.100 , pp. 1233-1239
    • Jurcic, J.G.1    Larson, S.M.2    Sgouros, G.3
  • 12
    • 0000281479 scopus 로고    scopus 로고
    • Targeted alpha-particle therapy for myeloid leukemias: A phase I trial of bismuth-213-HuM195 (anti-CD33) [abstract]
    • Jurcic JG, McDevitt MR, Sgouros G, et al. Targeted alpha-particle therapy for myeloid leukemias: a phase I trial of bismuth-213-HuM195 (anti-CD33) [abstract]. Blood. 1997;90:2245.
    • (1997) Blood , vol.90 , pp. 2245
    • Jurcic, J.G.1    McDevitt, M.R.2    Sgouros, G.3
  • 15
    • 20644447798 scopus 로고    scopus 로고
    • First clinical experience with alpha-emitting radium-223 in the treatment of skeletal metastases
    • Nilsson S, Larsen RH, Fossa SD, et al. First clinical experience with alpha-emitting radium-223 in the treatment of skeletal metastases. Clin Cancer Res. 2005;11:4451-4459.
    • (2005) Clin Cancer Res , vol.11 , pp. 4451-4459
    • Nilsson, S.1    Larsen, R.H.2    Fossa, S.D.3
  • 16
    • 34548503767 scopus 로고    scopus 로고
    • 211At-MX35 F(AB')(2) in therapy of ovarian cancer: Preliminary results from an ongoing phase I study [abstract]
    • 211At-MX35 F(AB')(2) in therapy of ovarian cancer: preliminary results from an ongoing phase I study [abstract]. Cancer Biother Radiopharm. 2006;21:395.
    • (2006) Cancer Biother Radiopharm , vol.21 , pp. 395
    • Hultborn, R.1    Andersson, H.2    Back, T.3
  • 19
    • 0037111144 scopus 로고    scopus 로고
    • Vascular targeted endoradiotherapy of tumors using alpha-particle-emitting compounds: Theoretical analysis
    • Akabani G, McLendon RE, Bigner DD, Zalutsky MR. Vascular targeted endoradiotherapy of tumors using alpha-particle-emitting compounds: theoretical analysis. Int J Radiat Oncol Biol Phys. 2002;54:1259-1275.
    • (2002) Int J Radiat Oncol Biol Phys , vol.54 , pp. 1259-1275
    • Akabani, G.1    McLendon, R.E.2    Bigner, D.D.3    Zalutsky, M.R.4
  • 21
    • 36849002083 scopus 로고    scopus 로고
    • Alpha-particle immunotherapy for acute myeloid leukemia (AML) with bismuth-213 and actinium-225 [abstract]
    • Jurcic JG, McDevitt MR, Pandit-Taskar N, et al. Alpha-particle immunotherapy for acute myeloid leukemia (AML) with bismuth-213 and actinium-225 [abstract]. Cancer Biother Radiopharm. 2006;21:396.
    • (2006) Cancer Biother Radiopharm , vol.21 , pp. 396
    • Jurcic, J.G.1    McDevitt, M.R.2    Pandit-Taskar, N.3
  • 22
    • 34250359790 scopus 로고
    • Some effects of alpha radiation upon plant cells
    • Zirkle RE. Some effects of alpha radiation upon plant cells. J Cell Comp Physiol. 1932;2:251-274.
    • (1932) J Cell Comp Physiol , vol.2 , pp. 251-274
    • Zirkle, R.E.1
  • 23
    • 10044228508 scopus 로고    scopus 로고
    • The centenary of the discovery of the Bragg peak
    • Brown A, Suit H. The centenary of the discovery of the Bragg peak. Radiother Oncol. 2004;73:265-268.
    • (2004) Radiother Oncol , vol.73 , pp. 265-268
    • Brown, A.1    Suit, H.2
  • 24
    • 0014002302 scopus 로고
    • The effect of oxygen on the impairment of the proliferative capacity of human cells in culture by ionizing radiations of different LET
    • Barendsen GW, Koot CJ, van Kerson GR, Bewley DK, Field SB, Parnell CJ. The effect of oxygen on the impairment of the proliferative capacity of human cells in culture by ionizing radiations of different LET. Int J Radiat Biol. 1966;10:317-327.
    • (1966) Int J Radiat Biol , vol.10 , pp. 317-327
    • Barendsen, G.W.1    Koot, C.J.2    van Kerson, G.R.3    Bewley, D.K.4    Field, S.B.5    Parnell, C.J.6
  • 25
    • 80155146078 scopus 로고
    • Effects of different ionizing radiations on human cells in tissue culture. IV. Modification of radiation damage
    • Barendsen GW, Walter HMD. Effects of different ionizing radiations on human cells in tissue culture. IV. Modification of radiation damage. Radiat Res. 1964;21:314-329.
    • (1964) Radiat Res , vol.21 , pp. 314-329
    • Barendsen, G.W.1    Walter, H.M.D.2
  • 26
    • 30644469586 scopus 로고
    • Modification of radiation damage by fractionation of dose anoxia + chemical protectors in relation to LET
    • Barendsen GW. Modification of radiation damage by fractionation of dose anoxia + chemical protectors in relation to LET. Ann N Y Acad Sci. 1964;114(A1):96-114.
    • (1964) Ann N Y Acad Sci , vol.114 , Issue.A1 , pp. 96-114
    • Barendsen, G.W.1
  • 27
    • 0011057882 scopus 로고
    • Impairment of the proliferative capacity of human cells in culture by alpha-particles with differing linear-energy transfer
    • Barendsen GW. Impairment of the proliferative capacity of human cells in culture by alpha-particles with differing linear-energy transfer. Int J Radiat Biol Relat Stud Phys Chem Med. 1964;8:453-466.
    • (1964) Int J Radiat Biol Relat Stud Phys Chem Med , vol.8 , pp. 453-466
    • Barendsen, G.W.1
  • 28
    • 84873775089 scopus 로고
    • Effects of different ionizing radiations on human cells in tissue culture. III. Experiments with cyclotron-accelerated alpha-particles and deuterons
    • Barendsen GW, Walter HMD, Bewley DK, Fowler JF. Effects of different ionizing radiations on human cells in tissue culture. III. Experiments with cyclotron-accelerated alpha-particles and deuterons. Radiat Res. 1963;18:106.
    • (1963) Radiat Res , vol.18 , pp. 106
    • Barendsen, G.W.1    Walter, H.M.D.2    Bewley, D.K.3    Fowler, J.F.4
  • 29
    • 0141871638 scopus 로고
    • Dose-survival curves of human cells in tissue culture irradiated with alpha-, beta-, 20-kv x- and 200-kv x-radiation
    • Barendsen GW. Dose-survival curves of human cells in tissue culture irradiated with alpha-, beta-, 20-kv x- and 200-kv x-radiation. Nature. 1962;193:1153.
    • (1962) Nature , vol.193 , pp. 1153
    • Barendsen, G.W.1
  • 30
    • 0011832878 scopus 로고
    • Effects of different ionizing radiations on human cells in tissue culture. I. Irradiation techniques and dosimetry
    • Barendsen GW, Beusker TLJ. Effects of different ionizing radiations on human cells in tissue culture. I. Irradiation techniques and dosimetry. Radiat Res. 1960;13:832-840.
    • (1960) Radiat Res , vol.13 , pp. 832-840
    • Barendsen, G.W.1    Beusker, T.L.J.2
  • 31
    • 84961060184 scopus 로고
    • Effect of different ionizing radiations on human cells in tissue culture. II. Biological experiments
    • Barendsen GW, Beusker TLJ, Vergroesen AJ, Budke L. Effect of different ionizing radiations on human cells in tissue culture. II. Biological experiments. Radiat Res. 1960;13:841-849.
    • (1960) Radiat Res , vol.13 , pp. 841-849
    • Barendsen, G.W.1    Beusker, T.L.J.2    Vergroesen, A.J.3    Budke, L.4
  • 32
    • 46949086423 scopus 로고
    • Irradiation of human cells in tissue culture with alpha-rays, beta-rays and x-rays [abstract]
    • Barendsen GW, Vergroesen AJ. Irradiation of human cells in tissue culture with alpha-rays, beta-rays and x-rays [abstract]. Int J Radiat Biol Relat Stud Phys Chem Med. 1960;2:441.
    • (1960) Int J Radiat Biol Relat Stud Phys Chem Med , vol.2 , pp. 441
    • Barendsen, G.W.1    Vergroesen, A.J.2
  • 33
    • 0018832242 scopus 로고
    • Mutation and inactivation of cultured mammalian cells exposed to beams of accelerated heavy ions. IV. Biophysical interpretation
    • Goodhead DT, Munson RJ, Thacker J, Cox R. Mutation and inactivation of cultured mammalian cells exposed to beams of accelerated heavy ions. IV. Biophysical interpretation. Int J Radiat Biol Relat Stud Phys Chem Med. 1980;37:135-167.
    • (1980) Int J Radiat Biol Relat Stud Phys Chem Med , vol.37 , pp. 135-167
    • Goodhead, D.T.1    Munson, R.J.2    Thacker, J.3    Cox, R.4
  • 34
    • 0018306675 scopus 로고
    • Mutation and inactivation of cultured mammalian cells exposed to beams of accelerated heavy ions. I. Irradiation facilities and methods
    • Munson RJ, Bance DA, Stretch A, Goodhead DT. Mutation and inactivation of cultured mammalian cells exposed to beams of accelerated heavy ions. I. Irradiation facilities and methods. Int J Radiat Biol Relat Stud Phys Chem Med. 1979;36:127-136.
    • (1979) Int J Radiat Biol Relat Stud Phys Chem Med , vol.36 , pp. 127-136
    • Munson, R.J.1    Bance, D.A.2    Stretch, A.3    Goodhead, D.T.4
  • 35
    • 0018293189 scopus 로고
    • Mutation and inactivation of cultured mammalian cells exposed to beams of accelerated heavy ions. II. Chinese hamster V79 cells
    • Thacker J, Stretch A, Stephens MA. Mutation and inactivation of cultured mammalian cells exposed to beams of accelerated heavy ions. II. Chinese hamster V79 cells. Int J Radiat Biol Relat Stud Phys Chem Med. 1979;36:137-148.
    • (1979) Int J Radiat Biol Relat Stud Phys Chem Med , vol.36 , pp. 137-148
    • Thacker, J.1    Stretch, A.2    Stephens, M.A.3
  • 36
    • 0018428545 scopus 로고
    • Mutation and inactivation of cultured mammalian cells exposed to beams of accelerated heavy ions. III. Human diploid fibroblasts
    • Cox R, Masson WK. Mutation and inactivation of cultured mammalian cells exposed to beams of accelerated heavy ions. III. Human diploid fibroblasts. Int J Radiat Biol Relat Stud Phys Chem Med. 1979;36:149-160.
    • (1979) Int J Radiat Biol Relat Stud Phys Chem Med , vol.36 , pp. 149-160
    • Cox, R.1    Masson, W.K.2
  • 37
    • 0022368952 scopus 로고
    • Energy distribution and the relative biological effects of internal alpha emitters
    • Fisher DR, Frazier ME, Andrews TK Jr. Energy distribution and the relative biological effects of internal alpha emitters. Radiat Prot Dosimetry. 1985;13:223-227.
    • (1985) Radiat Prot Dosimetry , vol.13 , pp. 223-227
    • Fisher, D.R.1    Frazier, M.E.2    Andrews Jr, T.K.3
  • 38
    • 0027158017 scopus 로고
    • A model of cell inactivation by alpha-particle internal emitters
    • Humm JL, Chin LM. A model of cell inactivation by alpha-particle internal emitters. Radiat Res. 1993;134:143-150.
    • (1993) Radiat Res , vol.134 , pp. 143-150
    • Humm, J.L.1    Chin, L.M.2
  • 39
    • 0035141515 scopus 로고    scopus 로고
    • Radioimmunotherapy with alpha-particle emitters: Microdosimetry of cells with a heterogeneous antigen expression and with various diameters of cells and nuclei
    • Kvinnsland Y, Stokke T, Aurlien E. Radioimmunotherapy with alpha-particle emitters: microdosimetry of cells with a heterogeneous antigen expression and with various diameters of cells and nuclei. Radiat Res. 2001;155:288-296.
    • (2001) Radiat Res , vol.155 , pp. 288-296
    • Kvinnsland, Y.1    Stokke, T.2    Aurlien, E.3
  • 40
    • 33746040560 scopus 로고    scopus 로고
    • Log normal distribution of cellular uptake of radioactivity: Implications for biologic responses to radiopharmaceuticals
    • Neti PVSV, Howell RW. Log normal distribution of cellular uptake of radioactivity: implications for biologic responses to radiopharmaceuticals. J Nucl Med. 2006;47:1049-1058.
    • (2006) J Nucl Med , vol.47 , pp. 1049-1058
    • Neti, P.V.S.V.1    Howell, R.W.2
  • 41
    • 0014803828 scopus 로고
    • Relative radiosensitivity of nucleus and cytoplasm of Chinese hamster fibroblasts
    • Munro TR. Relative radiosensitivity of nucleus and cytoplasm of Chinese hamster fibroblasts. Radiat Res. 1970;42:451-470.
    • (1970) Radiat Res , vol.42 , pp. 451-470
    • Munro, T.R.1
  • 43
    • 0026044529 scopus 로고
    • Radiobiology of alpha particles. III. Cell inactivation by alpha particle traversals of the cell nucleus
    • Raju MR, Eisen Y, Carpenter S, Inkret WC. Radiobiology of alpha particles. III. Cell inactivation by alpha particle traversals of the cell nucleus. Radiat Res. 1991;128:204-209.
    • (1991) Radiat Res , vol.128 , pp. 204-209
    • Raju, M.R.1    Eisen, Y.2    Carpenter, S.3    Inkret, W.C.4
  • 44
    • 0018822815 scopus 로고
    • Inactivation of synchronized Chinese hamster V79 cells with charged-particle track segments
    • Bird RP, Rohrig N, Colvett RD, Geard CR, Marino SA. Inactivation of synchronized Chinese hamster V79 cells with charged-particle track segments. Radiat Res. 1980;82:277-289.
    • (1980) Radiat Res , vol.82 , pp. 277-289
    • Bird, R.P.1    Rohrig, N.2    Colvett, R.D.3    Geard, C.R.4    Marino, S.A.5
  • 45
    • 0022295595 scopus 로고
    • Lethal, potentially lethal, and nonlethal damage induction by heavy-ions in cultured human-cells
    • Todd P, Wood JCS, Walker JT, Weiss SJ. Lethal, potentially lethal, and nonlethal damage induction by heavy-ions in cultured human-cells. Radiat Res. 1985;104(suppl):S5-S12.
    • (1985) Radiat Res , vol.104 , Issue.SUPPL.
    • Todd, P.1    Wood, J.C.S.2    Walker, J.T.3    Weiss, S.J.4
  • 46
    • 0023474421 scopus 로고
    • 238Pu alpha-particles on the mouse fibroblast cell line C3H 10T1/2: Characterization of source and RBE for cell survival
    • 238Pu alpha-particles on the mouse fibroblast cell line C3H 10T1/2: characterization of source and RBE for cell survival. Int J Radiat Biol Relat Stud Phys Chem Med. 1987;52:871-882.
    • (1987) Int J Radiat Biol Relat Stud Phys Chem Med , vol.52 , pp. 871-882
    • Roberts, C.J.1    Goodhead, D.T.2
  • 47
    • 0025080044 scopus 로고
    • LET dependence of linear and quadratic terms in dose-response relationships for cellular-damage: Correlations with the dimensions and structures of biological targets
    • Barendsen GW. LET dependence of linear and quadratic terms in dose-response relationships for cellular-damage: correlations with the dimensions and structures of biological targets. Radiat Prot Dosimetry. 1990;31:235-239.
    • (1990) Radiat Prot Dosimetry , vol.31 , pp. 235-239
    • Barendsen, G.W.1
  • 48
    • 0026332627 scopus 로고
    • The question of relative biological effectiveness and quality factor for auger emitters incorporated into proliferating mammalian cells
    • Howell RW, Rao DV, Hou DY, Narra VR, Sastry KSR. The question of relative biological effectiveness and quality factor for auger emitters incorporated into proliferating mammalian cells. Radiat Res. 1991;128:282-292.
    • (1991) Radiat Res , vol.128 , pp. 282-292
    • Howell, R.W.1    Rao, D.V.2    Hou, D.Y.3    Narra, V.R.4    Sastry, K.S.R.5
  • 49
    • 0026720658 scopus 로고
    • Cellular kinetics, dosimetry, and radiobiology of alpha-particle radioimmunotherapy: Induction of apoptosis
    • Macklis RM, Lin JY, Beresford B, Atcher RW, Hines JJ, Humm JL. Cellular kinetics, dosimetry, and radiobiology of alpha-particle radioimmunotherapy: induction of apoptosis. Radiat Res. 1992;130:220-226.
    • (1992) Radiat Res , vol.130 , pp. 220-226
    • Macklis, R.M.1    Lin, J.Y.2    Beresford, B.3    Atcher, R.W.4    Hines, J.J.5    Humm, J.L.6
  • 50
    • 0024369699 scopus 로고
    • Calculation of initial yields of single-strand and double-strand breaks in cell-nuclei from electrons, protons and alpha-particles
    • Charlton DE, Nikjoo H, Humm JL. Calculation of initial yields of single-strand and double-strand breaks in cell-nuclei from electrons, protons and alpha-particles. Int J Radiat Biol. 1989;56:1-19.
    • (1989) Int J Radiat Biol , vol.56 , pp. 1-19
    • Charlton, D.E.1    Nikjoo, H.2    Humm, J.L.3
  • 51
    • 0029874665 scopus 로고    scopus 로고
    • Use of chord lengths through the nucleus to simulate the survival of mammalian cells exposed to high LET alpha-radiation
    • Charlton DE, Turner MS. Use of chord lengths through the nucleus to simulate the survival of mammalian cells exposed to high LET alpha-radiation. Int J Radiat Biol. 1996;69:213-217.
    • (1996) Int J Radiat Biol , vol.69 , pp. 213-217
    • Charlton, D.E.1    Turner, M.S.2
  • 52
    • 0025268911 scopus 로고
    • A generalized state-vector model for radiation-induced cellular transformation
    • Crawford-Brown DJ, Hofmann W. A generalized state-vector model for radiation-induced cellular transformation. Int J Radiat Biol. 1990;57:407-423.
    • (1990) Int J Radiat Biol , vol.57 , pp. 407-423
    • Crawford-Brown, D.J.1    Hofmann, W.2
  • 53
    • 0035692369 scopus 로고    scopus 로고
    • Correlated hit probability and cell transformation in an effect-specific track length model applied to in vitro alpha irradiation
    • Crawford-Brown DJ, Hofmann W. Correlated hit probability and cell transformation in an effect-specific track length model applied to in vitro alpha irradiation. Radiat Environ Biophys. 2001;40:317-323.
    • (2001) Radiat Environ Biophys , vol.40 , pp. 317-323
    • Crawford-Brown, D.J.1    Hofmann, W.2
  • 54
    • 0343022568 scopus 로고
    • Articles on the biology of radiation effects: Analysis on nematode eggs
    • Holthusen H. Articles on the biology of radiation effects: analysis on nematode eggs. Pflugers Arch Gesamte Physiol Menschen Tiere. 1921;187:1-24.
    • (1921) Pflugers Arch Gesamte Physiol Menschen Tiere , vol.187 , pp. 1-24
    • Holthusen, H.1
  • 55
    • 84966192535 scopus 로고
    • The histological structure of some human lung cancers and the possible implications for radiotherapy
    • Thomlinson RH, Gray LH. The histological structure of some human lung cancers and the possible implications for radiotherapy. Br J Cancer. 1955;9:539-549.
    • (1955) Br J Cancer , vol.9 , pp. 539-549
    • Thomlinson, R.H.1    Gray, L.H.2
  • 56
    • 0038282482 scopus 로고    scopus 로고
    • The hypoxia-inducible factor-1 alpha is a negative factor for tumor therapy
    • Unruh A, Ressel A, Mohamed HG, et al. The hypoxia-inducible factor-1 alpha is a negative factor for tumor therapy. Oncogene. 2003;22:3213-3220.
    • (2003) Oncogene , vol.22 , pp. 3213-3220
    • Unruh, A.1    Ressel, A.2    Mohamed, H.G.3
  • 57
    • 0345605687 scopus 로고
    • Oxygen-dependent sensitization of irradiated cells
    • Meyn RE, Withers HR, eds, New York, NY: Raven Press;
    • Ewing D, Powers EL. Oxygen-dependent sensitization of irradiated cells. In: Meyn RE, Withers HR, eds. Radiation Biology in Cancer Research. New York, NY: Raven Press; 1979:143-168.
    • (1979) Radiation Biology in Cancer Research , pp. 143-168
    • Ewing, D.1    Powers, E.L.2
  • 59
    • 2042439959 scopus 로고    scopus 로고
    • The international workshop on health effects of Thorotrast, radium, radon and other alpha-emitters, 1999 [preface]
    • Machinami R, Ishikawa Y, Boecker BB. The international workshop on health effects of Thorotrast, radium, radon and other alpha-emitters, 1999 [preface]. Radiat Res. 1999;152(suppl):S1-S2.
    • (1999) Radiat Res , vol.152 , Issue.SUPPL.
    • Machinami, R.1    Ishikawa, Y.2    Boecker, B.B.3
  • 60
    • 4444325509 scopus 로고    scopus 로고
    • International Commission on Radiological Protection, Philadelphia, PA: Elsevier;, ICRP publication 92
    • R). Philadelphia, PA: Elsevier; 2004. ICRP publication 92.
    • (2004) R)
  • 61
    • 0037250921 scopus 로고    scopus 로고
    • Quantitative comparisons of cancer induction in humans by internally deposited radionuclides and external radiation
    • Harrison JD, Muirhead CR. Quantitative comparisons of cancer induction in humans by internally deposited radionuclides and external radiation. Int J Radiat Biol. 2003;79:1-13.
    • (2003) Int J Radiat Biol , vol.79 , pp. 1-13
    • Harrison, J.D.1    Muirhead, C.R.2
  • 62
    • 0032520269 scopus 로고    scopus 로고
    • The development of a [At-211]-astatinated endoradio-therapeutic drug: Part IV - late radiation effects
    • Brown I, Mitchell JS. The development of a [At-211]-astatinated endoradio-therapeutic drug: Part IV - late radiation effects. Int J Radiat Oncol Biol Phys. 1998;40:1177-1183.
    • (1998) Int J Radiat Oncol Biol Phys , vol.40 , pp. 1177-1183
    • Brown, I.1    Mitchell, J.S.2
  • 63
    • 0000479690 scopus 로고
    • The induction of tumors in the rat by astatine-211
    • Durbin PW, Asling CW, Johnston ME, et al. The induction of tumors in the rat by astatine-211. Radiat Res. 1958;9:378-397.
    • (1958) Radiat Res , vol.9 , pp. 378-397
    • Durbin, P.W.1    Asling, C.W.2    Johnston, M.E.3
  • 64
    • 0010562419 scopus 로고
    • Tumor induction with astatine-211 in rats: Characterization of pituitary tumors
    • Yokoro K, Kunii A, Furth J, Durbin PW. Tumor induction with astatine-211 in rats: characterization of pituitary tumors. Cancer Res. 1964;24:683-688.
    • (1964) Cancer Res , vol.24 , pp. 683-688
    • Yokoro, K.1    Kunii, A.2    Furth, J.3    Durbin, P.W.4
  • 65
    • 0027477449 scopus 로고
    • The radiobiology of radiosurgery: Rationale for different treatment regimes for AVMs and malignancies
    • Hall EJ, Brenner DJ. The radiobiology of radiosurgery: rationale for different treatment regimes for AVMs and malignancies. Int J Radiat Oncol Biol Phys. 1993;25:381-385.
    • (1993) Int J Radiat Oncol Biol Phys , vol.25 , pp. 381-385
    • Hall, E.J.1    Brenner, D.J.2
  • 66
    • 0033048040 scopus 로고    scopus 로고
    • The assessment of RBE effects using the concept of biologically effective dose
    • Dale RG, Jones B. The assessment of RBE effects using the concept of biologically effective dose. Int J Radiat Oncol Biol Phys. 1999;43:639-645.
    • (1999) Int J Radiat Oncol Biol Phys , vol.43 , pp. 639-645
    • Dale, R.G.1    Jones, B.2
  • 67
    • 0032530658 scopus 로고    scopus 로고
    • Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells
    • Takata M, Sasaki MS, Sonoda E, et al. Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells. EMBO J. 1998;17:5497-5508.
    • (1998) EMBO J , vol.17 , pp. 5497-5508
    • Takata, M.1    Sasaki, M.S.2    Sonoda, E.3
  • 68
    • 0037340911 scopus 로고    scopus 로고
    • Oliveira NG, CastroM, Rodrigues AS, et al.Wortmannin enhances the induction of micronuclei by low and high LET radiation [erratum]. Mutagenesis. 2003;18:217.
    • Oliveira NG, CastroM, Rodrigues AS, et al.Wortmannin enhances the induction of micronuclei by low and high LET radiation [erratum]. Mutagenesis. 2003;18:217.
  • 69
    • 0037236752 scopus 로고    scopus 로고
    • Wortmannin enhances the induction of micronuclei by low and high LET radiation
    • Oliveira NG, Castro M, Rodrigues AS, et al. Wortmannin enhances the induction of micronuclei by low and high LET radiation. Mutagenesis. 2003;18:37-44.
    • (2003) Mutagenesis , vol.18 , pp. 37-44
    • Oliveira, N.G.1    Castro, M.2    Rodrigues, A.S.3
  • 70
    • 0028068123 scopus 로고
    • Vitamins as radioprotectors in vivo. II. Protection by vitamin A and soybean oil against radiation-damage caused by internal radionuclides
    • Harapanhalli RS, Narra VR, Yaghmai V, et al. Vitamins as radioprotectors in vivo. II. Protection by vitamin A and soybean oil against radiation-damage caused by internal radionuclides. Radiat Res. 1994;139:115-122.
    • (1994) Radiat Res , vol.139 , pp. 115-122
    • Harapanhalli, R.S.1    Narra, V.R.2    Yaghmai, V.3
  • 71
    • 0028798398 scopus 로고
    • Radioprotection against biological effects of internal radionuclides in vivo by S-(2-aminoethyl)isothiouronium bromide hydrobromide (AET)
    • Narra VR, Harapanhalli RS, Goddu SM, Howell RW, Rao DV. Radioprotection against biological effects of internal radionuclides in vivo by S-(2-aminoethyl)isothiouronium bromide hydrobromide (AET). J Nucl Med. 1995;36:259-266.
    • (1995) J Nucl Med , vol.36 , pp. 259-266
    • Narra, V.R.1    Harapanhalli, R.S.2    Goddu, S.M.3    Howell, R.W.4    Rao, D.V.5
  • 73
    • 0026081261 scopus 로고
    • Induction of sperm head abnormalities by incorporated radionuclides: Dependence on subcellular distribution, type of radiation, dose rate, and presence of radioprotectors
    • Rao DV, Narra VR, Howell RW, Lanka VK, Sastry KSR. Induction of sperm head abnormalities by incorporated radionuclides: dependence on subcellular distribution, type of radiation, dose rate, and presence of radioprotectors. Radiat Res. 1991;125:89-97.
    • (1991) Radiat Res , vol.125 , pp. 89-97
    • Rao, D.V.1    Narra, V.R.2    Howell, R.W.3    Lanka, V.K.4    Sastry, K.S.R.5
  • 74
    • 0030461523 scopus 로고    scopus 로고
    • Radioprotection by DMSO against the biological effects of incorporated radionuclides in vivo: Comparison with other radioprotectors and evidence for indirect action of Auger electrons
    • Goddu SM, Narra VR, Harapanhalli RS, Howell RW, Rao DV. Radioprotection by DMSO against the biological effects of incorporated radionuclides in vivo: comparison with other radioprotectors and evidence for indirect action of Auger electrons. Acta Oncol. 1996;35:901-907.
    • (1996) Acta Oncol , vol.35 , pp. 901-907
    • Goddu, S.M.1    Narra, V.R.2    Harapanhalli, R.S.3    Howell, R.W.4    Rao, D.V.5
  • 75
    • 0028230463 scopus 로고
    • Vitamins as radioprotectors in vivo. I. Protection by vitamin C against internal radionuclides in mouse testes: Implications to the mechanism of damage caused by the Auger effect
    • Narra VR, Harapanhalli R, Howell RW, Sastry KSR, Rao DV. Vitamins as radioprotectors in vivo. I. Protection by vitamin C against internal radionuclides in mouse testes: implications to the mechanism of damage caused by the Auger effect. Radiat Res. 1994;137:394-399.
    • (1994) Radiat Res , vol.137 , pp. 394-399
    • Narra, V.R.1    Harapanhalli, R.2    Howell, R.W.3    Sastry, K.S.R.4    Rao, D.V.5
  • 77
    • 33645787453 scopus 로고
    • International Commission on Radiological Protection, Philadelphia, PA: Elsevier;, ICRP publication 58
    • International Commission on Radiological Protection. RBE for Deterministic Effects. Philadelphia, PA: Elsevier; 1990. ICRP publication 58.
    • (1990) RBE for Deterministic Effects
  • 78
    • 0026630293 scopus 로고
    • Interlaboratory comparison of different alpha-particle and radon sources: Cell survival and relative biological effectiveness
    • Schwartz JL, Rotmensch J, Atcher RW, et al. Interlaboratory comparison of different alpha-particle and radon sources: cell survival and relative biological effectiveness. Health Phys. 1992;62:458-461.
    • (1992) Health Phys , vol.62 , pp. 458-461
    • Schwartz, J.L.1    Rotmensch, J.2    Atcher, R.W.3
  • 79
    • 0025946151 scopus 로고
    • In vitro exposure of mammalian cells to radon: Dosimetric considerations
    • Jostes RF, Hui TE, James AC, et al. In vitro exposure of mammalian cells to radon: dosimetric considerations. Radiat Res. 1991;127:211-219.
    • (1991) Radiat Res , vol.127 , pp. 211-219
    • Jostes, R.F.1    Hui, T.E.2    James, A.C.3
  • 80
    • 0031824907 scopus 로고    scopus 로고
    • Theoretical treatment of human haemopoietic stem cell survival following irradiation by alpha particles
    • Charlton DE, Utteridge TD, Allen BJ. Theoretical treatment of human haemopoietic stem cell survival following irradiation by alpha particles. Int J Radiat Biol. 1998;74:111-118.
    • (1998) Int J Radiat Biol , vol.74 , pp. 111-118
    • Charlton, D.E.1    Utteridge, T.D.2    Allen, B.J.3
  • 81
    • 0031042038 scopus 로고    scopus 로고
    • Radiotoxicity of gadolinium-148 and radium-223 in mouse testes: Relative biological effectiveness of alpha-particle emitters in vivo
    • Howell RW, Goddu SM, Narra VR, Fisher DR, Schenter RE, Rao DV. Radiotoxicity of gadolinium-148 and radium-223 in mouse testes: relative biological effectiveness of alpha-particle emitters in vivo. Radiat Res. 1997;147:342-348.
    • (1997) Radiat Res , vol.147 , pp. 342-348
    • Howell, R.W.1    Goddu, S.M.2    Narra, V.R.3    Fisher, D.R.4    Schenter, R.E.5    Rao, D.V.6
  • 82
    • 0030973228 scopus 로고    scopus 로고
    • Design and performance characteristics of an experimental cesium-137 irradiator to simulate internal radionuclide dose rate patterns
    • Howell RW, Goddu SM, Rao DV. Design and performance characteristics of an experimental cesium-137 irradiator to simulate internal radionuclide dose rate patterns. J Nucl Med. 1997;38:727-731.
    • (1997) J Nucl Med , vol.38 , pp. 727-731
    • Howell, R.W.1    Goddu, S.M.2    Rao, D.V.3
  • 84
    • 0030790965 scopus 로고    scopus 로고
    • Meeting report: Alpha-emitters for medical therapy - Workshop of the United States Department of Energy, Denver, Colorado, May 30-31, 1996
    • Feinendegen LE, McClure JJ. Meeting report: Alpha-emitters for medical therapy - Workshop of the United States Department of Energy, Denver, Colorado, May 30-31, 1996. Radiat Res. 1997;148:195-201.
    • (1997) Radiat Res , vol.148 , pp. 195-201
    • Feinendegen, L.E.1    McClure, J.J.2
  • 85
    • 0025930020 scopus 로고
    • 1990 recommendations of the International Commission on Radiological Protection
    • 1990 recommendations of the International Commission on Radiological Protection. Ann ICRP. 1991;21:1-201.
    • (1991) Ann ICRP , vol.21 , pp. 1-201
  • 86
    • 58149130161 scopus 로고    scopus 로고
    • Radiation protection in medicine: ICRP publication 105
    • Radiation protection in medicine: ICRP publication 105. Ann ICRP. 2007;37: 1-63.
    • (2007) Ann ICRP , vol.37 , pp. 1-63
  • 88
    • 0028294851 scopus 로고
    • Multicellular dosimetry for micrometastases: Dependence of self-dose versus cross-dose to cell nuclei on type and energy of radiation and subcellular distribution of radionuclides
    • Goddu SM, Rao DV, Howell RW. Multicellular dosimetry for micrometastases: dependence of self-dose versus cross-dose to cell nuclei on type and energy of radiation and subcellular distribution of radionuclides. J Nucl Med. 1994;35:521-530.
    • (1994) J Nucl Med , vol.35 , pp. 521-530
    • Goddu, S.M.1    Rao, D.V.2    Howell, R.W.3
  • 89
    • 0033767471 scopus 로고    scopus 로고
    • Radiation effects in spheroids of cells exposed to alpha emitters
    • Charlton DE. Radiation effects in spheroids of cells exposed to alpha emitters. Int J Radiat Biol. 2000;76:1555-1564.
    • (2000) Int J Radiat Biol , vol.76 , pp. 1555-1564
    • Charlton, D.E.1
  • 90
    • 0030708731 scopus 로고    scopus 로고
    • Microdosimetry of astatine-211 using histological images: Application to bone marrow
    • Akabani G, Zalutsky MR. Microdosimetry of astatine-211 using histological images: application to bone marrow. Radiat Res. 1997;148:599-607.
    • (1997) Radiat Res , vol.148 , pp. 599-607
    • Akabani, G.1    Zalutsky, M.R.2
  • 91
  • 92
    • 0025904373 scopus 로고
    • Transport of fluid and macromolecules in tumors. IV. A microscopic model of the perivascular distribution
    • Baxter LT, Jain RK. Transport of fluid and macromolecules in tumors. IV. A microscopic model of the perivascular distribution. Microvasc Res. 1991;41:252-272.
    • (1991) Microvasc Res , vol.41 , pp. 252-272
    • Baxter, L.T.1    Jain, R.K.2
  • 93
    • 0024232289 scopus 로고
    • Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: Significance of elevated interstitial pressure
    • Jain RK, Baxter LT. Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: significance of elevated interstitial pressure. Cancer Res. 1988;48:7022-7032.
    • (1988) Cancer Res , vol.48 , pp. 7022-7032
    • Jain, R.K.1    Baxter, L.T.2
  • 94
    • 0026442158 scopus 로고
    • Plasmapheresis in radioimmunotherapy of micrometastases: A mathematical modeling and dosimetrical analysis
    • Sgouros G. Plasmapheresis in radioimmunotherapy of micrometastases: a mathematical modeling and dosimetrical analysis. J Nucl Med. 1992;33: 2167-2179.
    • (1992) J Nucl Med , vol.33 , pp. 2167-2179
    • Sgouros, G.1
  • 96
    • 0028087258 scopus 로고
    • Cellular dosimetry: Absorbed fractions for monoenergetic electron and alpha particle sources and S-values for radionuclides uniformly distributed in different cell compartments
    • Goddu SM, Howell RW, Rao DV. Cellular dosimetry: absorbed fractions for monoenergetic electron and alpha particle sources and S-values for radionuclides uniformly distributed in different cell compartments. J Nucl Med. 1994;35:303-316.
    • (1994) J Nucl Med , vol.35 , pp. 303-316
    • Goddu, S.M.1    Howell, R.W.2    Rao, D.V.3
  • 97
    • 0000928055 scopus 로고
    • Localized alpha-dosimetry
    • Eberg M, Howard A, eds, Amsterdam, The Netherlands: Elsevier;
    • Polig E. Localized alpha-dosimetry. In: Eberg M, Howard A, eds. Current Topics in Radiation Research. Vol 13. Amsterdam, The Netherlands: Elsevier; 1978:189-327.
    • (1978) Current Topics in Radiation Research , vol.13 , pp. 189-327
    • Polig, E.1
  • 98
    • 0002501106 scopus 로고
    • Microdosimetric energy distribution in irradiated matter
    • Attx FH, Roesch WC, eds, New York, NY: Academic Press;
    • Rossi HH. Microdosimetric energy distribution in irradiated matter. In: Attx FH, Roesch WC, eds. Radiation Dosimetry. Vol 1. New York, NY: Academic Press; 1968.
    • (1968) Radiation Dosimetry , vol.1
    • Rossi, H.H.1
  • 99
    • 0017638164 scopus 로고
    • Microdosimetry of internal sources
    • Roesch WC. Microdosimetry of internal sources. Radiat Res. 1977;70:494-510.
    • (1977) Radiat Res , vol.70 , pp. 494-510
    • Roesch, W.C.1
  • 100
    • 0042498869 scopus 로고
    • The microdosimetry of monoclonal antibodies labeled with alpha emitters
    • Schlafke-Stelson AT, Watson EE, eds, Oak Ridge, TN: Oak Ridge Associated Universities;
    • Fisher DR. The microdosimetry of monoclonal antibodies labeled with alpha emitters. In: Schlafke-Stelson AT, Watson EE, eds. Fourth International Radiopharmaceutical Dosimetry Symposium. Oak Ridge, TN: Oak Ridge Associated Universities; 1986:26-36.
    • (1986) Fourth International Radiopharmaceutical Dosimetry Symposium , pp. 26-36
    • Fisher, D.R.1
  • 101
    • 0028115036 scopus 로고
    • Analysis of survival of C-18 cells after irradiation in suspension with chelated and ionic bismuth-212 using microdosimetry
    • Stinchcomb TG, Roeske JC. Analysis of survival of C-18 cells after irradiation in suspension with chelated and ionic bismuth-212 using microdosimetry. Radiat Res. 1994;140:48-54.
    • (1994) Radiat Res , vol.140 , pp. 48-54
    • Stinchcomb, T.G.1    Roeske, J.C.2
  • 102
    • 0026454246 scopus 로고
    • Analytic microdosimetry for radioimmunotherapeutic alpha emitters
    • Stinchcomb TG, Roeske JC. Analytic microdosimetry for radioimmunotherapeutic alpha emitters. Med Phys. 1992;19:1385-1393.]
    • (1992) Med Phys , vol.19 , pp. 1385-1393
    • Stinchcomb, T.G.1    Roeske, J.C.2
  • 103
    • 0041497127 scopus 로고
    • Analysis of patterns of energy deposition: A survey of theoretical relations in microdosimetry
    • Ebert HG, ed, Brussels, Belgium: Commission of European Communities;
    • Kellerer AM. Analysis of patterns of energy deposition: a survey of theoretical relations in microdosimetry. In: Ebert HG, ed. Proceedings of the Second Symposium on Microdosimetry. Brussels, Belgium: Commission of European Communities; 1970:107-134.
    • (1970) Proceedings of the Second Symposium on Microdosimetry , pp. 107-134
    • Kellerer, A.M.1
  • 104
    • 0025097003 scopus 로고
    • Energy deposition by protons and alpha-particles in spherical sites of nanometer to micrometer diameter
    • Olko P, Booz J. Energy deposition by protons and alpha-particles in spherical sites of nanometer to micrometer diameter. Radiat Environ Biophys. 1990;29:1-17.
    • (1990) Radiat Environ Biophys , vol.29 , pp. 1-17
    • Olko, P.1    Booz, J.2
  • 106
    • 75749101271 scopus 로고    scopus 로고
    • Ziegler JF. The stopping and range of ions in solids (Stopping and Range of Ions in Matter, 1). New York, NY: Pergamon; 1985.
    • Ziegler JF. The stopping and range of ions in solids (Stopping and Range of Ions in Matter, Vol. 1). New York, NY: Pergamon; 1985.
  • 107
    • 75749149989 scopus 로고    scopus 로고
    • Bichsel H. Stopping Powers of Fast Charged Particles in Heavy Elements. Springfield, VA: U.S. National Technical Information Service; 1992. NIST report IR-4550.
    • Bichsel H. Stopping Powers of Fast Charged Particles in Heavy Elements. Springfield, VA: U.S. National Technical Information Service; 1992. NIST report IR-4550.
  • 108
    • 0003697463 scopus 로고
    • International Commission on Radiation Units and Measurements, Bethesda, MD: ICRU;, ICRU publication 49
    • International Commission on Radiation Units and Measurements. Stopping Powers and Ranges for Protons and Alpha Particles. Bethesda, MD: ICRU; 1993. ICRU publication 49.
    • (1993) Stopping Powers and Ranges for Protons and Alpha Particles
  • 109
    • 0016784109 scopus 로고
    • Criteria for applicability of LET
    • Kellerer AM, Chmelevsky D. Criteria for applicability of LET. Radiat Res. 1975;63:226-234.
    • (1975) Radiat Res , vol.63 , pp. 226-234
    • Kellerer, A.M.1    Chmelevsky, D.2
  • 110
    • 0031442829 scopus 로고    scopus 로고
    • Dosimetric framework for therapeutic alpha-particle emitters
    • Roeske JC, Stinchcomb TG. Dosimetric framework for therapeutic alpha-particle emitters. J Nucl Med. 1997;38:1923-1929.
    • (1997) J Nucl Med , vol.38 , pp. 1923-1929
    • Roeske, J.C.1    Stinchcomb, T.G.2
  • 112
    • 0032589284 scopus 로고    scopus 로고
    • Values of "S," 〈z1〉, and 〈(z1)2〉 for dosimetry using alpha-particle emitters
    • Stinchcomb TG, Roeske JC. Values of "S," 〈z1〉, and 〈(z1)2〉 for dosimetry using alpha-particle emitters. Med Phys. 1999;26:1960-1971.
    • (1999) Med Phys , vol.26 , pp. 1960-1971
    • Stinchcomb, T.G.1    Roeske, J.C.2
  • 113
    • 75749157619 scopus 로고
    • Specific energy distributions for alpha emitters in the dog lung
    • Fisher DR. Specific energy distributions for alpha emitters in the dog lung. Ann Occup Hyg. 1988;32(suppl 1):1095-1104.
    • (1988) Ann Occup Hyg , vol.32 , Issue.SUPPL. 1 , pp. 1095-1104
    • Fisher, D.R.1
  • 114
    • 0023629230 scopus 로고
    • A microdosimetric model of astatine-211 labeled antibodies for 0radioimmunotherapy
    • Humm JL. A microdosimetric model of astatine-211 labeled antibodies for 0radioimmunotherapy. Int J Radiat Oncol Biol Phys. 1987;13:1767-1773.
    • (1987) Int J Radiat Oncol Biol Phys , vol.13 , pp. 1767-1773
    • Humm, J.L.1
  • 115
    • 0029584704 scopus 로고
    • Survival of alpha particle irradiated cells as a function of the shape and size of the sensitive volume (nucleus)
    • Stinchcomb TG, Roeske JC. Survival of alpha particle irradiated cells as a function of the shape and size of the sensitive volume (nucleus). Radiat Prot Dosimetry. 1995;62:157-164.
    • (1995) Radiat Prot Dosimetry , vol.62 , pp. 157-164
    • Stinchcomb, T.G.1    Roeske, J.C.2
  • 117
    • 33846045110 scopus 로고    scopus 로고
    • Modelling the effect of non-uniform radon progeny activities on transformation frequencies in human bronchial airways
    • Fakir H, Hofmann W, Aubineau-Laniece I. Modelling the effect of non-uniform radon progeny activities on transformation frequencies in human bronchial airways. Radiat Prot Dosimetry. 2006;121:221-235.
    • (2006) Radiat Prot Dosimetry , vol.121 , pp. 221-235
    • Fakir, H.1    Hofmann, W.2    Aubineau-Laniece, I.3
  • 118
    • 33646263860 scopus 로고    scopus 로고
    • Microdosimetry of radon progeny alpha particles in bronchial airway bifurcations
    • Fakir H, Hofmann W, Aubineau-Laniece I. Microdosimetry of radon progeny alpha particles in bronchial airway bifurcations. Radiat Prot Dosimetry. 2005;117:382-394.
    • (2005) Radiat Prot Dosimetry , vol.117 , pp. 382-394
    • Fakir, H.1    Hofmann, W.2    Aubineau-Laniece, I.3
  • 119
    • 18844448176 scopus 로고    scopus 로고
    • Microdosimetry of inhomogeneous radon progeny distributions in bronchial airways
    • Fakir H, Hofmann W, Caswell RS, Aubineau-Laniece I. Microdosimetry of inhomogeneous radon progeny distributions in bronchial airways. Radiat Prot Dosimetry. 2005;113:129-139.
    • (2005) Radiat Prot Dosimetry , vol.113 , pp. 129-139
    • Fakir, H.1    Hofmann, W.2    Caswell, R.S.3    Aubineau-Laniece, I.4
  • 120
    • 1242344875 scopus 로고    scopus 로고
    • Microdosimetry of astatine-211 single-cell irradiation: Role of daughter polonium-211 diffusion
    • Palm S, Humm JL, Rundqvist R, Jacobsson L. Microdosimetry of astatine-211 single-cell irradiation: role of daughter polonium-211 diffusion. Med Phys. 2004;31:218-225.
    • (2004) Med Phys , vol.31 , pp. 218-225
    • Palm, S.1    Humm, J.L.2    Rundqvist, R.3    Jacobsson, L.4
  • 121
    • 0036149168 scopus 로고    scopus 로고
    • Alpha-particle-induced increases in the radioresistance of normal human bystander cells
    • Iyer R, Lehnert BE. Alpha-particle-induced increases in the radioresistance of normal human bystander cells. Radiat Res. 2002;157:3-7.
    • (2002) Radiat Res , vol.157 , pp. 3-7
    • Iyer, R.1    Lehnert, B.E.2
  • 122
    • 0031770716 scopus 로고    scopus 로고
    • Intercellular communication is involved in the bystander regulation of gene expression in human cells exposed to very low fluences of alpha particles
    • Azzam EI, de Toledo SM, Gooding T, Little JB. Intercellular communication is involved in the bystander regulation of gene expression in human cells exposed to very low fluences of alpha particles. Radiat Res. 1998;150:497-504.
    • (1998) Radiat Res , vol.150 , pp. 497-504
    • Azzam, E.I.1    de Toledo, S.M.2    Gooding, T.3    Little, J.B.4
  • 123
    • 0034813139 scopus 로고    scopus 로고
    • Monte Carlo modeling of the effects of injected short-, medium- and longer-range alpha-particle emitters on human marrow at various ages
    • Utteridge TD, Charlton DE, Allen BJ. Monte Carlo modeling of the effects of injected short-, medium- and longer-range alpha-particle emitters on human marrow at various ages. Radiat Res. 2001;156:413-418.
    • (2001) Radiat Res , vol.156 , pp. 413-418
    • Utteridge, T.D.1    Charlton, D.E.2    Allen, B.J.3
  • 124
    • 0033433971 scopus 로고    scopus 로고
    • A schema for estimating absorbed dose to organs following the administration of radionuclides with multiple unstable daughters: A matrix approach
    • Hamacher KA, Sgouros G. A schema for estimating absorbed dose to organs following the administration of radionuclides with multiple unstable daughters: a matrix approach. Med Phys. 1999;26:2526-2528.
    • (1999) Med Phys , vol.26 , pp. 2526-2528
    • Hamacher, K.A.1    Sgouros, G.2
  • 125
    • 75749137161 scopus 로고    scopus 로고
    • Fisher DR, Sgouros G. Dosimetry of radium-223 and progeny. In: Stelson AT, Stabin MG, Sparks RB, eds. Proceedings of the Sixth International Radiopharmaceutical Dosimetry Symposium. Gatlinburg, TN: U.S. Department of Energy and Oak Ridge Associated Universities; 1999:375-391.
    • Fisher DR, Sgouros G. Dosimetry of radium-223 and progeny. In: Stelson AT, Stabin MG, Sparks RB, eds. Proceedings of the Sixth International Radiopharmaceutical Dosimetry Symposium. Gatlinburg, TN: U.S. Department of Energy and Oak Ridge Associated Universities; 1999:375-391.
  • 126
    • 0033863361 scopus 로고    scopus 로고
    • Long-lived alpha emitters in radioimmunotherapy: The mischievous progeny
    • Sgouros G. Long-lived alpha emitters in radioimmunotherapy: the mischievous progeny. Cancer Biother Radiopharm. 2000;15:219-221.
    • (2000) Cancer Biother Radiopharm , vol.15 , pp. 219-221
    • Sgouros, G.1
  • 128
    • 0034898674 scopus 로고    scopus 로고
    • Cellular dose conversion factors for alpha-particle-emitting radionuclides of interest in radionuclide therapy
    • Hamacher KA, Den RB, Den EI, Sgouros G. Cellular dose conversion factors for alpha-particle-emitting radionuclides of interest in radionuclide therapy. J Nucl Med. 2001;42:1216-1221.
    • (2001) J Nucl Med , vol.42 , pp. 1216-1221
    • Hamacher, K.A.1    Den RB, D.E.2    Sgouros, G.3
  • 130
    • 33644942120 scopus 로고    scopus 로고
    • 227Th-p-benzyl-DOTA-rituximab for low-dose rate alpha-particle radioimmunotherapy
    • 227Th-p-benzyl-DOTA-rituximab for low-dose rate alpha-particle radioimmunotherapy. Nucl Med Biol. 2006;33:271-279.
    • (2006) Nucl Med Biol , vol.33 , pp. 271-279
    • Dahle, J.1    Borrebaek, J.2    Melhus, K.B.3
  • 131
    • 34548829082 scopus 로고    scopus 로고
    • Targeted cancer therapy with a novel low dose rate alpha-emitting radioimmunoconjugate
    • Dahle J, Borrebaek J, Jonasdottir TJ, et al. Targeted cancer therapy with a novel low dose rate alpha-emitting radioimmunoconjugate. Blood. 2007;110:2049-2056.
    • (2007) Blood , vol.110 , pp. 2049-2056
    • Dahle, J.1    Borrebaek, J.2    Jonasdottir, T.J.3
  • 132
    • 16744365716 scopus 로고    scopus 로고
    • MIRD pamphlet no. 16: Techniques for quantitative radiopharmaceutical biodistribution data acquisition and analysis for use in human radiation dose estimates
    • Siegel JA, Thomas SR, Stubbs JB, et al. MIRD pamphlet no. 16: techniques for quantitative radiopharmaceutical biodistribution data acquisition and analysis for use in human radiation dose estimates. J Nucl Med. 1999;40(suppl):37S-61S.
    • (1999) J Nucl Med , vol.40 , Issue.SUPPL.
    • Siegel, J.A.1    Thomas, S.R.2    Stubbs, J.B.3
  • 133
    • 0002063909 scopus 로고    scopus 로고
    • Treatment planning for internal emitter therapy: Methods, applications and clinical implications
    • Schafke-Stelson AT, Watson EE, eds, TN. Oak Ridge, TN: Oak Ridge Associated Universities;
    • Sgouros G. Treatment planning for internal emitter therapy: methods, applications and clinical implications. In: Schafke-Stelson AT, Watson EE, eds. Proceedings of the 6th International Radiopharmaceutical Dosimetry Symposium, May 7-10, 1996, Gatlinburg, TN. Oak Ridge, TN: Oak Ridge Associated Universities; 1996:13-24.
    • (1996) Proceedings of the 6th International Radiopharmaceutical Dosimetry Symposium, May 7-10, 1996, Gatlinburg , pp. 13-24
    • Sgouros, G.1
  • 134
    • 0007404549 scopus 로고    scopus 로고
    • Radioimmunotherapy of micrometastases
    • Riva P, ed, Newark, NJ: Harwood Academic Publishers;
    • Sgouros G. Radioimmunotherapy of micrometastases. In: Riva P, ed. Cancer Radioimmunotherapy: Present and Future. Newark, NJ: Harwood Academic Publishers; 1998:191-207.
    • (1998) Cancer Radioimmunotherapy: Present and Future , pp. 191-207
    • Sgouros, G.1
  • 135
    • 0016480306 scopus 로고
    • 131I-19-iodocholesterol: The pitfalls of using tissue concentration data [reply]
    • 131I-19-iodocholesterol: the pitfalls of using tissue concentration data [reply]. J Nucl Med. 1975;16:248-249.
    • (1975) J Nucl Med , vol.16 , pp. 248-249
    • Kirschner, A.S.1    Ice, R.D.2    Beierwaltes, W.H.3
  • 137
    • 0036145740 scopus 로고    scopus 로고
    • Site-specific variability in trabecular bone dosimetry: Considerations of energy loss to cortical bone
    • Patton PW, Rajon DA, Shah AP, Jokisch DW, Inglis BA, Bolch WE. Site-specific variability in trabecular bone dosimetry: considerations of energy loss to cortical bone. Med Phys. 2002;29:6-14.
    • (2002) Med Phys , vol.29 , pp. 6-14
    • Patton, P.W.1    Rajon, D.A.2    Shah, A.P.3    Jokisch, D.W.4    Inglis, B.A.5    Bolch, W.E.6
  • 138
    • 0036156891 scopus 로고    scopus 로고
    • Considerations of marrow cellularity in 3-dimensional dosimetric models of the trabecular skeleton
    • Bolch WE, Patton PW, Rajon DA, Shah AP, Jokisch DW, Inglis BA. Considerations of marrow cellularity in 3-dimensional dosimetric models of the trabecular skeleton. J Nucl Med. 2002;43:97-108.
    • (2002) J Nucl Med , vol.43 , pp. 97-108
    • Bolch, W.E.1    Patton, P.W.2    Rajon, D.A.3    Shah, A.P.4    Jokisch, D.W.5    Inglis, B.A.6
  • 139
    • 0038621641 scopus 로고    scopus 로고
    • Adipocyte spatial distributions in bone marrow: Implications for skeletal dosimetry models
    • Shah AP, Patton PW, Rajon DA, Bolch WE. Adipocyte spatial distributions in bone marrow: implications for skeletal dosimetry models. J Nucl Med. 2003;44:774-783.
    • (2003) J Nucl Med , vol.44 , pp. 774-783
    • Shah, A.P.1    Patton, P.W.2    Rajon, D.A.3    Bolch, W.E.4
  • 140
    • 18844384616 scopus 로고    scopus 로고
    • Accounting for beta-particle energy loss to cortical bone via paired-image radiation transport (PIRT)
    • Shah AP, Rajon DA, Patton PW, Jokisch DW, Bolch WE. Accounting for beta-particle energy loss to cortical bone via paired-image radiation transport (PIRT). Med Phys. 2005;32:1354-1366.
    • (2005) Med Phys , vol.32 , pp. 1354-1366
    • Shah, A.P.1    Rajon, D.A.2    Patton, P.W.3    Jokisch, D.W.4    Bolch, W.E.5
  • 141
    • 23844461543 scopus 로고    scopus 로고
    • Absorbed fractions for alpha-particles in tissues of trabecular bone: Considerations of marrow cellularity within the ICRP reference male
    • Watchman CJ, Jokisch DW, Patton PW, Rajon DA, Sgouros G, Bolch WE. Absorbed fractions for alpha-particles in tissues of trabecular bone: considerations of marrow cellularity within the ICRP reference male. J Nucl Med. 2005; 46:1171-1185.
    • (2005) J Nucl Med , vol.46 , pp. 1171-1185
    • Watchman, C.J.1    Jokisch, D.W.2    Patton, P.W.3    Rajon, D.A.4    Sgouros, G.5    Bolch, W.E.6
  • 142
    • 62449175592 scopus 로고    scopus 로고
    • MIRD pamphlet no. 21: A generalized schema for radiopharmaceutical dosimetry - standardization of nomenclature
    • Bolch WE, Eckerman KF, Sgouros G, Thomas SR. MIRD pamphlet no. 21: a generalized schema for radiopharmaceutical dosimetry - standardization of nomenclature. J Nucl Med. 2009;50:477-484.
    • (2009) J Nucl Med , vol.50 , pp. 477-484
    • Bolch, W.E.1    Eckerman, K.F.2    Sgouros, G.3    Thomas, S.R.4
  • 144
    • 0014559581 scopus 로고
    • Estimates of absorbed fractions for monoenergetic photon sources uniformly distributed in various organs of a heterogeneous phantom
    • Snyder WS, Fisher HL, Ford MR, Warner GG. Estimates of absorbed fractions for monoenergetic photon sources uniformly distributed in various organs of a heterogeneous phantom. J Nucl Med. 1969;10(suppl):7-52.
    • (1969) J Nucl Med , vol.10 , Issue.SUPPL. , pp. 7-52
    • Snyder, W.S.1    Fisher, H.L.2    Ford, M.R.3    Warner, G.G.4
  • 145
    • 0032694041 scopus 로고    scopus 로고
    • A three-dimensional transport model for determining absorbed fractions of energy for electrons within trabecular bone
    • Bouchet LG, Jokisch DW, Bolch WE. A three-dimensional transport model for determining absorbed fractions of energy for electrons within trabecular bone. J Nucl Med. 1999;40:1947-1966.
    • (1999) J Nucl Med , vol.40 , pp. 1947-1966
    • Bouchet, L.G.1    Jokisch, D.W.2    Bolch, W.E.3
  • 147
    • 62449191032 scopus 로고    scopus 로고
    • MIRD commentary: Proposed name for a dosimetry unit applicable to deterministic biological effects - the Barendsen (Bd)
    • Sgouros G, Howell RW, Bolch WE, Fisher DR. MIRD commentary: proposed name for a dosimetry unit applicable to deterministic biological effects - the Barendsen (Bd). J Nucl Med. 2009;50:485-487.
    • (2009) J Nucl Med , vol.50 , pp. 485-487
    • Sgouros, G.1    Howell, R.W.2    Bolch, W.E.3    Fisher, D.R.4
  • 148
    • 33745697736 scopus 로고    scopus 로고
    • Kneifel S, Cordier D, Good S, et al. Local targeting of malignant gliomas by the diffusible peptidic vector 1,4,7,10-tetraazacyclododecane-1-glutaric acid-4,7,10-triacetic acid-substance P. Clin Cancer Res. 2006;12:3843-3850.
    • Kneifel S, Cordier D, Good S, et al. Local targeting of malignant gliomas by the diffusible peptidic vector 1,4,7,10-tetraazacyclododecane-1-glutaric acid-4,7,10-triacetic acid-substance P. Clin Cancer Res. 2006;12:3843-3850.
  • 150
    • 31144463014 scopus 로고    scopus 로고
    • Intralesional targeted alpha therapy for metastatic melanoma
    • Allen BJ, Raja C, Rizvi S, et al. Intralesional targeted alpha therapy for metastatic melanoma. Cancer Biol Ther. 2005;4:1318-1324.
    • (2005) Cancer Biol Ther , vol.4 , pp. 1318-1324
    • Allen, B.J.1    Raja, C.2    Rizvi, S.3
  • 151
    • 33746707858 scopus 로고    scopus 로고
    • High-linear energy transfer irradiation targeted to skeletal metastases by the alpha-emitter Ra-223: Adjuvant or alternative to conventional modalities?
    • Bruland OS, Nilsson S, Fisher DR, Larsen RH. High-linear energy transfer irradiation targeted to skeletal metastases by the alpha-emitter Ra-223: adjuvant or alternative to conventional modalities? Clin Cancer Res. 2006;12(suppl): 6250S-6257S.
    • (2006) Clin Cancer Res , vol.12 , Issue.SUPPL.
    • Bruland, O.S.1    Nilsson, S.2    Fisher, D.R.3    Larsen, R.H.4
  • 152
    • 34347244905 scopus 로고    scopus 로고
    • Bone-targeted radium-223 in symptomatic, hormone-refractory prostate cancer: A randomised, multicentre, placebo-controlled phase II study
    • Nilsson S, Franzen L, Parker C, et al. Bone-targeted radium-223 in symptomatic, hormone-refractory prostate cancer: a randomised, multicentre, placebo-controlled phase II study. Lancet Oncol. 2007;8:587-594.
    • (2007) Lancet Oncol , vol.8 , pp. 587-594
    • Nilsson, S.1    Franzen, L.2    Parker, C.3
  • 153
    • 75749090676 scopus 로고    scopus 로고
    • Goodhead DT. Talk 23, Alpha Emitters, from Session 6, Effects from Specific Sources of Internal Radiation. Presented at: CERRIE Workshop; July 21-23, 2003; Oxford, U.K.
    • Goodhead DT. Talk 23, Alpha Emitters, from Session 6, Effects from Specific Sources of Internal Radiation. Presented at: CERRIE Workshop; July 21-23, 2003; Oxford, U.K.
  • 155


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.