Vascular-targeted radioimmunotherapy with the alpha-particle emitter 211At

Radiation Research

Volumn 157, Issue 6, 2002, Pages 633-641

  Kennel, S J ^a   Mirzadeh, S ^a   Eckelman, W C ^a   Waldmann, T A ^a   Garmestani, K ^a   Yordanov, A T ^a   Stabind, M G ^a   Brechbiel, M W ^a  

^a Life Sciences Division   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASTATINE 211; BISMUTH 213; GLYCINE; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 201B; MONOCLONAL ANTIBODY AT 211; MONOCLONAL ANTIBODY BI 213; N SUCCINIMIDYL N (4 ASTATOPHENETHYL) SUCCINAMATE AT 211; SUCCINIMIDE DERIVATIVE; UNCLASSIFIED DRUG;

ALPHA RADIATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG DISTRIBUTION; ISOTOPE LABELING; LIFESPAN; LUNG FIBROSIS; LUNG TUMOR; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE DISTRIBUTION; RADIATION INJURY; RADIOIMMUNOTHERAPY; TISSUE DISTRIBUTION;

ANIMALIA;

EID: 0036267458     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/0033-7587(2002)157[0633:VTRWTA]2.0.CO;2     Document Type: Article

References (43)

1. Effect of antiangiogenic therapy on slowly growing, poorly vascularized tumors in mice
2. Effects of angiogenesis inhibitors on multistage carcinogenesis in mice
3. Complete inhibition of angiogenesis and growth of microtumors by anti-vascular endothelial growth factor neutralizing antibody: Novel concepts of angiostatic therapy from intravital videomicroscopy
4. Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
5. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumor growth in vivo
6. Synergy between an antiangiogenic integrin alpha v antagonist and an antibody-cytokine fusion protein eradicates spontaneous tumor metastases
7. Vascular targeting: A new approach to the therapy of solid tumors
8. Vasculature as a target for tumor therapy
9. Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model
10. Tumor infarction in mice by antibody-directed targeting of tissue factor to tumor vasculature
11. Infarction of solid Hodgkin's tumors in mice by antibody-directed targeting of tissue factor to tumor vasculature
12. 213Bi
13. 213Bi - An alpha particle emitter
14. 213Bi
15. Angiogenesis and cancer AACR special conference in cancer research
16. 213Bi
17. 225Ac for vascular targeted radioimmunotherapy of lung tumors
18. 211At produced in disposable internal and external bismuth targets
19. 211At labeling of humanized anti-Tac
20. Cyclotron isotopes and radiopharmaceuticals - XXXV: Astatine-211
21. Quantitation of thrombomodulin in BALB/c organs suggests preferential expression in lung microvessels
22. Quantitation of a specific murine lung endothelial cell protein, P 112, with a double monoclonal antibody assay
23. Analysis of surface proteins of mouse lung carcinomas using monoclonal antibodies
24. Monoclonal antibody targeting of liposomes to mouse lung in vivo
25. Developing and testing integrated multicompartment models to describe a single-input multi-output study using SAAM II software system
26. 131I-labeled monoclonal antibody MOv 18 in nude mice with intraperitoneal growth of human ovarian cancer
27. 211At-methylene blue for targeted radiotherapy of disseminated melanoma: Microscopic analysis of tumour versus normal tissue damage
28. Radioimmunotherapy of neoplastic meningitis in rats using an α-particle immunoconjugate
29. Tissue distribution and radiation dosimetry of astatine-211-labeled chimeric 81C6, an alpha-particle-emitting immunoconjugate
30. Astatine-211-labeled radiotherapeutics: An emerging approach to targeted alpha-particle radiotherapy
31. Increased binding affinity and valence of recombinant antibody fragments lead to improved targeting of tumoral angiogenesis
32. Radioimmunotherapy: Recent results and future directions
33. Microdosimetry of astatine-211 using histological images: Application to bone marrow
34. 90Y-labeled CO17-1A Fab' fragments in a human colonic cancer model
35. 211At-labeled human/mouse chimeric monoclonal antibody: A long-term survival study with histologic analysis
36. 211At]astatide in B6C3F1 and BALB/c (nu/nu) mice: A longterm survival study with histologic analysis
37. Selective targeting of tumour neovasculature by a radiohalogenated human antibody fragment specific for the ED-B domain of fibronectin
38. 211At]astato-3-pyridinecarboxylate
39. 131I-labeled monoclonal antibodies
40. Use of yttrium-90-labeled antibody in primate xenograft transplantation
41. Chronic hypoxia modulates tumour cell radioresponse through cytokine-inducible nitric oxide synthetase
42. Role of the immune system in mediating the antitumor effect of benzophenothiazine photodynamic therapy
43. Particles initiate biological production of superoxide anions and hydrogen peroxide in human cells