Development of gelucire 43/01 beads of metformin hydrochloride for floating delivery

AAPS PharmSciTech

Volumn 10, Issue 4, 2009, Pages 1128-1136

  Jain, Sunil K ^a   Gupta, Anuj ^a  

^a GURU GHASIDAS UNIVERSITY   (India)

Author keywords

Aging effect; Beads; Floating drug delivery; Gelucire 43 01; Metformin HCl

Indexed keywords

DRUG CARRIER; GELUCIRE; METFORMIN; WATER;

ARTICLE; CHEMICAL INTERACTION; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM; DRUG RELEASE; DRUG SOLUBILITY; DRUG STORAGE; IN VITRO STUDY; MELTING POINT; MICROSCOPY; MORPHOLOGY; PARTICLE SIZE; POROSITY; SCANNING ELECTRON MICROSCOPY; SUSTAINED RELEASE FORMULATION; TEMPERATURE; THERMOGRAPHY;

CALORIMETRY, DIFFERENTIAL SCANNING; DRUG DELIVERY SYSTEMS; HYPOGLYCEMIC AGENTS; METFORMIN; PARTICLE SIZE; SOLUBILITY; TRIGLYCERIDES;

EID: 75549091402     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-009-9302-6     Document Type: Article

References (28)

1. P Zimmet 1999 Diabetes epidemiology as a trigger to diabetes research and care Diabetologia 42 5 499 518 10.1007/s001250051188 1:STN:280: DyaK1M3mtlygtA%3D%3D 10333041 (Pubitemid 29195999)
2. Davis SN, Granner DK. Insulin, oral hypoglycemic agents and the pharmacology of the endocrine pancreas. In: Hardman JG, Limbrid LE, editors. Goodman & Gilman's the pharmacological basis of therapeutics. 10th ed. USA: McGraw-Hill Medical Publishing Division; 2001. p. 1705-1706.
3. A Patel S Ray RS Thakur 2006 In vitro evaluation and optimization of controlled release floating drug delivery system of metformin hydrochloride Daru 14 3 57 69 1:CAS:528:DC%2BD28XhtF2qsLfK
4. BN Singh KM Kim 2000 Floating drug delivery systems: an approach to oral controlled drug delivery via gastric retention J Control Release 63 235 259 10.1016/S0168-3659(99)00204-7 1:CAS:528:DyaK1MXnvFSmu7w%3D 10601721
5. S Baumgartner J Kristel F Vreer P Vodopivec B Zorko 2000 Optimization of floating matrix tablets and evaluation of their gastric residence time Int J Pharm 195 125 135 10.1016/S0378-5173(99)00378-6 1:CAS:528:DC%2BD3cXhtV2hsb8%3D 10675690 (Pubitemid 30089497)
6. SK Jain AM Awasthi NK Jain GP Agrawal 2005 Calcium silicate based microspheres of repaglinide for gastroretentive floating drug delivery: preparation and in vitro characterization J Control Release 107 300 309 10.1016/j.jconrel.2005.06.007 1:CAS:528:DC%2BD2MXhtVShtr%2FN 16095748 (Pubitemid 41316292)
7. SK Jain GP Agrawal NK Jain 2006 A novel calcium silicate based microspheres of repaglinide: in vivo investigations J Control Release 113 111 116 10.1016/j.jconrel.2006.04.005 1:CAS:528:DC%2BD28Xmt1Wrt7w%3D 16759733 (Pubitemid 43928144)
8. SK Jain GP Agrawal NK Jain 2006 Evaluation of porous carrier-based floating microspheres for gastric delivery AAPS PharmSciTech 7 4 Article 90 10.1208/pt070490
9. SK Jain GP Agrawal NK Jain 2007 Porous carrier based floating granular delivery system of repaglinide Drug Dev Ind Pharm 33 381 391 10.1080/03639040600920655 1:CAS:528:DC%2BD2sXls1Snt78%3D 17523003 (Pubitemid 46808786)
10. AK Jain SK Jain A Yadav GP Agrawal 2006 Controlled release calcium silicate based floating granular delivery system of ranitidine hydrochloride Curr Drug Del 3 4 367 372 10.2174/156720106778559083 1:CAS:528: DC%2BD28XhtVChtb%2FO (Pubitemid 44534048)
11. B Chauhan S Shimpi KR Mahadik A Paradkar 2005 Preparation and evaluation of floating risedronate sodium-Gelucire 43/01 formulations Drug Dev Ind Pharm 31 851 860 10.1080/03639040500271837 1:CAS:528:DC%2BD2MXht1Wntb3E 16305996 (Pubitemid 41540936)
12. W Bowtle 2000 Lipid formulations for oral drug delivery Pharm Tech Europe 12 20 30 1:CAS:528:DC%2BD3cXntVSitr4%3D
13. A Ainaoui JM Vergnaud 1998 Modeling the plasma drug level with oral controlled release forms with lipidic Gelucire Int J Pharm 169 155 162 10.1016/S0378-5173(98)00105-7 1:CAS:528:DyaK1cXkslGnsr0%3D (Pubitemid 28345251)
14. A Ainaoui EM Ouriemchi D Bidah MK El Amrani JM Vergnaud 1997 Process of drug release with oral dosage forms with lipidic gelucire matrix J Polym Eng 17 245 257 1:CAS:528:DyaK2sXlslWlsbo%3D
15. MT Sheu A Hsia HO Ho 2001 Polyglycolized saturated glycerides as carrier and enhancer for drug penetration Chin Pharm J 53 107 111 1:CAS:528: DC%2BD3MXnvVynsrw%3D
16. W Sutananta DQM Craig JM Newton 1994 The effects of ageing on the thermal behavior and mechanical properties of pharmaceutical glycerides Int J Pharm 111 51 62 10.1016/0378-5173(94)90401-4 1:CAS:528:DyaK2cXmtlyhsbc%3D (Pubitemid 24277378)
17. SA Barker SP Yap KH Yuen CP McCoy JR Murphy DQM Craig 2003 An investigation into the structure and bioavailability of α-tocopherol dispersion in Gelucire 44/14 J Control Release 91 477 488 10.1016/S0168-3659(03) 00261-X 1:CAS:528:DC%2BD3sXmsVSrtL4%3D 12932724 (Pubitemid 36976774)
18. AB Dennis SJ Farr IW Kellaway G Taylor R Davidson 1990 In vivo evaluation of rapid release and sustained release Gelucire capsule formulations Int J Pharm 65 85 100 10.1016/0378-5173(90)90013-T 1:CAS:528:DyaK3MXkvFCksA%3D%3D
19. DM Patel NM Patel VF Patel DA Bhatt 2008 Floating granules of ranitidine hydrochloride-Gelucire 43/01: formulation optimization using factorial design AAPS PharmSciTech 8 2 Article 30
20. K Kumar MH Shah A Ketkar KP Mahadik A Paradkar 2004 Effect of drug solubility and different excipients on floating behavior and release from glyceryl mono-oleate matrices Int J Pharm 272 151 160 10.1016/j.ijpharm.2003.12. 025 1:CAS:528:DC%2BD2cXhs1Ghs7k%3D (Pubitemid 38293020)
21. S Shimpi B Chauhan KR Mahadik A Paradkar 2004 Preparation and evaluation of Diltiazem Hydrochloride-Gelucire 43/01 floating granules prepared by melt granulation AAPS PharmSciTech 5 3 Article 43 10.1208/pt050343
22. W Sutananta DQM Craig JM Newton 1995 An evaluation of the mechanisms of drug release from glycerides bases J Pharm Pharmacol 47 182 187 1:CAS:528:DyaK2MXkvFeju70%3D 7602477
23. E James G Singh L Larry P Vinod 1997 Methods to compare dissolution profiles and a rationale for wide dissolution specification for metoprolol tartrate tablets J Pharm Sci 86 690 700 10.1021/js960473x (Pubitemid 27248819)
24. PC Wu MJ Tsai YB Huang JS Cheng YH Tsai 2002 In vitro and in vivo evaluation of potassium chloride sustained release formulation prepared with saturated polyglycolyed glycerides matrices Int J Pharm 243 1-2 119 124 10.1016/S0378-5173(02)00264-8 1:CAS:528:DC%2BD38Xmt1ygtLk%3D 12176300 (Pubitemid 34907962)
25. F Quaglia F Barbato GD Rosa E Granata A Miro MI Rotonda 2001 Reduction of the environmental impact of pesticides: waxy microspheres encapsulating the insecticide carbaryl Agric Food Chem 49 10 4808 4812 10.1021/jf010418w 1:CAS:528:DC%2BD3MXmvFChurk%3D (Pubitemid 32988723)
26. C Sanker C Mishra 2003 Development and in vitro evaluations of gelatin microspheres of ketorolac tromethamine for intranasal administration Acta Pharm 53 101 110
27. SK Jain M Jangde 2009 Lectin conjugated gastro-retentive multiparticulate delivery system of clarithromycin for the effective treatment of helicobacter pylori Mol Pharm 6 1 295 304 10.1021/mp800193n 1:CAS:528:DC%2BD1cXhsFWqsrnP 19093870
28. Y Murata N Sasaki E Miyamoto S Kawashima 2000 Use of floating alginate gel beads for stomach specific drug delivery Eur J Pharm Biopharm 50 221 226 10.1016/S0939-6411(00)00110-7 1:CAS:528:DC%2BD3cXlvFWhsbg%3D 10962231 (Pubitemid 30674333)