Lipid formulations for oral drug delivery

Pharmaceutical Technology Europe

Volumn 12, Issue 9, 2000, Pages

  Bowtle, W ^a  

^a MW Encap Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AEROSIL; AEROSIL A200; AKOLINE; AKOMED; ALPHA PENTYL 3 (2 QUINOLYLMETHOXY)BENZYL ALCOHOL; AMINE; ANTIMALARIAL AGENT; BETA LACTAM ANTIBIOTIC; CAPMUL MCM; CAPROL ET; CAPTEX 200; CAPTEX 300; CAPTEX 355; CEFMETAZOLE; CHLORIDE; DIMYRISTOYLPHOSPHATIDYLGLYCEROL; DRUG CARRIER; DYSNASAN 114; FATTY ACID DERIVATIVE; FENOFIBRATE; GELUCIRE; GELUCIRE 44-14; GELUCIRE 46 07; GELUCIRE 50 02; GELUCIRE 50 13; GELUCIRE 55 18; GLYCEROL BEHENATE; GLYCEROL PALMITOSTEARATE; HYDROXYPROPYLMETHYLCELLULOSE; IMWITOR 308; IMWITOR 708; IMWITOR 742; IMWITOR 780K; IMWITOR 908; IMWITOR 988; LABRAFAC LIPOPHIL; LABRASOL; LAUROGLYCOL; LIPID; MACROGOL; MACROGOL 1000; MACROGOL 4000; MEDIUM CHAIN TRIACYLGLYCEROL; MELINAMIDE; MIGLYOL; MIGLYOL 810; MIGLYOL 829; MYVACET 9 08; MYVACET 940; NIFEDIPINE; PECEOL; PEGLICOL 5 OLEATE; PIROXICAM; PLUROL OLEIQUE; PROPANTHELINE BROMIDE; PROPRANOLOL; PROPYLENE GLYCOL; SIMULSOL; SIMULSOL M; SOFTIGEN 767; SOFTISAN 133; SOFTISAN 134; SOFTISAN 138; SUPPOCIRE; SURFACTANT; THEOPHYLLINE; TOLBUTAMIDE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; UNINDEXED DRUG; VEGETABLE OIL;

DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG MANUFACTURE; DRUG METABOLISM; DRUG MIXTURE; DRUG NOMENCLATURE; DRUG RELEASE; DRUG SOLUBILITY; DRUG STORAGE; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PHYSICAL CHEMISTRY; REVIEW;

EID: 0033826380     PISSN: 01646826     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (34)

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2. Medium chain triglycerides: An update
3. Effect of lipid on bioavailability of sulfisoxazole acetyl, dicumarol and griseolvin in rats
4. Enhancement of bioavailability of a hydrophobic amine antimalarial by formulation with oleic acid in a soft gelatin capsule
5. Biopharmaceutical studies of lipid-containing oral dosage forms: Relationship between drug absorption rate and digestibility of vehicles
6. Improvement of bioavailability of poorly intestinally absorbed drugs from medium-chain glyceride base. Enhancement of the rectal absorption of cefmetazole sodium in rabbits
7. An investigation into the effects of preparation conditions on the structure and mechanical properties of pharmaceutical glyceride bases
8. Physical and chemical characterization of thermosoftened bases for molten filled hard gelatin capsule formulations
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10. The use of dielectric analysis as a means of characterizing the effects of moisture uptake by pharmaceutical glyceride bases
11. Formulation and processing issues for liquid-filled hard gelatin capsules
12. Liquid filling of hard gelatin capsules
13. Soft gelatin encapsulation of liquid and semi-solid oral formulations and capsules
14. Effect of vehicle amphiphilicity on the dissolution and bioavailability of a poorly water-soluble drug from solid dispersions
15. Digestible emulsions and microemulsions for optimum oral delivery of hydrophobic drugs
16. Demonstration of the importance of biphasic delivery for enhancing the bioavailability of propranolol in healthy volunteers
17. Formulation strategies designed to maintain the biphasic release characteristics of liquid-filled capsules
18. Microemulsions
19. Design and Formulation of Self-Emulsifying Drug Delivery Systems (SEDDS)
20. Development of formulations with self-emulsifying ability to enhance solubility and oral bioavailability of fenofibrate
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23. Evaluation of release from selected thermosoftening vehicles
24. Diffusional process of drug delivery from a dosage form with a gelucire matrix
25. Formulation and physical properties of thixotropic gels for hard gelatin capsules
26. The effect of oil viscosity on drug delivery from lipid formulations in liquid-filled hard gelatin capsules
27. Accelerated stability study of sustained-release nifedipine tablets prepared with gelucire
28. An investigation into the effects of preparation conditions and storage on the rate of drug release from pharmaceutical glyceride bases
29. Formulation design and manufacturing of oral lipid-based dosage units
30. Glyceride-based excipients for controlled drug release
31. Suitability of two-piece HPMC capsules for oxygen-sensitive liquids
32. Food components with potential therapeutic benefits: The n-3 polyunsaturated fatty acids of fish oils
33. A novel chemical approach to drug delivery: Lipid amino acid conjugates