Invitro evaluation and optimization of controlled release Floating Drug Delivery System of metformin hydrochloride

Daru

Volumn 14, Issue 2, 2006, Pages 57-64

  Patel, Asha ^a   Ray, Subhabrata ^a   Thakur, Ram Sharnagat ^a  

^a KRUPANIDHI COLLEGE OF PHARMACY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ETHYL CELLULOSE; METFORMIN; MICROSPHERE; POLYMER;

ARTICLE; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG RELEASE; DRUG SYNTHESIS; EMULSION; ENCAPSULATION; HIGH TEMPERATURE; IN VITRO STUDY; NONAQUEOUS PHASE LIQUID; PARTICLE SIZE; STOMACH ABSORPTION; TOPOGRAPHY;

EID: 33745653878     PISSN: 15608115     EISSN: 15608115     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. th ed. New York: Lippincott Williams and Wilkins; 2002. p. 641-648.
2. Stepensky D, Friedman M, Srour W, Raz I, Hoffman A. Preclinical evaluation of pharmacokinetic-pharmacodynamic rationale for oral CR metformin formulation. J Control Rel 2001; 71:107-115,.
3. Noel M. Kinetic study of normal and sustained release dosage forms of metformin in normal subjects. J Int Biomed Data 1980; 1:9-20,
4. Pentikainen P. Bioavailability of metformin. Comparison of solution, rapidly dissolving tablet, and three sustained release products. Int J Clin Pharmacol Ther Toxicol 1986; 24 (4): 213-220.
5. Yuen KH, Peh KK, Tan BL. Relating in vitro/ in vivo data of two controlled release metformin formulations. Drug Dev Ind Pharm 1999; 25 (5): 613-618.
6. th Scientific Sessions, San Antonio, Texas, 2000.
7. Gusler G, Berner B. Metformin (GR) gastric retentive tablets: GI transit and pharmacokinetics in healthy volunteers, In: Millennial World Congress of Pharmaceutical Science, San Francisco, California, 2000.
8. Metformin info (www.Rxlist.com ; accessed 5/10/2005).
9. Vidon N, Chaussade S, Noel M, Franchisseur C, Huchet B, Bernier JJ. Metformin in the digestive tract. Diabetes Res Clin Pract 1998; 4:223-229.
10. Marathe PH, Wen Y, Norton J, Greene DS, Barbhaiya RH, Wilding IR. Effect of altered gastric emptying and gastrointestinal motility on bioavailability of metformin, in: AAPS Annual Meeting, New Orleans, LA, 1999.
11. El-Kamel AH, Sokar MS, Al Gamal SS, Naggar VF. Preparation and evaluation of ketoprofen floating oral delivery system. Int J Pharm 2001; 220:13-21.
12. Iannuccelli V, Coppi G, Bernabei MT, Cameroni R. Air compartment multiple-unit system for prolonged gastric residence. Part I. Formulation study. Int J Pharm 1998; 174:47-54.
13. Acikgoz M, Kas HS, Hascelik Z, Milli U, Hincal AA. Chitosan microspheres of diclofenac sodium, II: In vitro and in vivo evaluation. Pharmazie 1995; 50:275-77.
14. Thanoo BC, Sunny MC, Jayakrishna A. Oral sustained -release drug delivery system using polycarbonate microspheres capable of floating on the gastric fluid. J Pharm Pharmacol 1993; 45:21-24.
15. Streubel A, Siepmann J, Bodmeier R. Floating microparticles based on low density foam powder. Int J Pharm 2002; 241:279-292.
16. Streubel A, Siepmann J, Bodmeier R. Multiple unit gastroretentive drug delivery systems: a new preparation method for low-density microparticles. J Microencapsulation 2003; 20 (3):329-347.
17. Jayanthi G, Jayaswal SB, Srivastava AK. Formulation and evaluation of terfenadine microballoons for oral controlled release. Pharmazie 1995; 50:769-770.
18. Sato Y, Kawashima Y, Takeuchi H, Yamamoto H. In vivo evaluation of riboflavin-containing microballoons for floating controlled drug delivery system in healthy human volunteers. J Control Rel 93:39-47, 2003.
19. Deasy PB. Microencapsulation and related drug processes. Marcel Dekker Inc; 1984.
20. Benita S. Microencapsulation: methods and industrial applications. Vol. 73, Mercel Dekker, Inc.; 1996.
21. Rao KR, Senapati P, Das MK. Formulation and in vitro evaluation of ethyl cellulose microspheres containing zidovudine. J Microencapsul 2005; 22(8): 863-876.
22. Srivastava AK, Ridhurkar DN, Wadha S. floating microspheres of cimetidine: formulation, characterization and in vitro evaluation. Acta Pharm 2005; 55(3): 277-285.
23. Wu PC, Huang YB, Chang JI, Tsai MJ, Tsai YH. Preparation and evaluation of sustained release microspheres of potassium chloride preapred with ethylcellulose. Int J Pharm 2003; 260(1):115-121.
24. Dinarvand R, Mirfattahi s, Atyabi F. Preparation, characterization and in vitro drug release of isosorbide dinitrate microspheres. J Microencapsul 2002; 19(1): 73-81.
25. Ray S, Ghosh PK, Das B, Ghosh LK, Gupta BK. Statistical optimization supported product development of anti-asthamatic multiparticulate drug delivery system. Indian J Pharm Sci 2000; 62(3): 175-80,.
26. Barik BB, Ray S, Goswami N, Gupta BK, Ghosh LK. Preparation and in vitro dissolution of Isoniazid from ethylcellulose microcapsules. Acta Poloniae Pharm 2001; 28(1): 65-68.
27. Jain SK, Awasthi AM, Jain NK, Agrawal GP. Calcium silicate based microspheres of repaglinide for gastroretentive floating drug delivery: Preparation and in vitro characterization. 2005; J Control Release 8:8.
28. Rouge N, Allemann E, Gex-Fabry M, Balant L, Cole ET, Buri P, et al. Comparatie pharmacokinetics study of a floating multiple-unit capsule, a high-density multiple-unit capsule and an immediate-release tablet containing 25 ng atenolol. Pharm Acta Helv 1998; 73(2): 81-87.
29. El-Gibaly I. Development and in vitro evaluation of novel floating chitosan microcapsules for oral use: comparison with non-floating chitosan microspheres. Int J Pharm 2002; 249(1-2): 7-21.
30. (a) Kawashima Y, Niwa T, Takeuchi H, Hino T, Itoh Y. Preparation of multiple unit hollow microspheres (microballoons) with acrylic resin containing tranilast and their drug rleease characteristics (in vitro) and floating behaviour (in vitro). J Control Rel 1991; 16:279-290.
31. (b) Kawashima Y, Niwa T, Takeuchi H, Hino T, Itoh Y. Ibid. Hollow microspheres for use as a floating controlled drug delivery system in the stomach. J Pharm Sci 1992; 81: 135-40.
32. Reddy LHV, Murthy RSR. Floating dosage systems in drug delivery. Crit Rev Ther Drug Carrer Syst 2002; 19(6): 553-585,.
33. Talukdar R, Fassihi R. Gastroretentive delivery systems: a mini review. Drug Dev Ind Pharm 2004; 30(10): 1019-1028.
34. Soppimath KS, Kulkarni AR, Rudzinski WE, Aminabhavi TM. Microspheres as floating drug-delivery systems to increase gastric retention of drugs. Drug Metab Rev, 2001; 33(2): 149-160.
35. Gouldson MP, Deasy PB. Use of cellulose ether containing excipients with microcrystalline cellulose for the production of pellets containing metformin hydrochloride by the process of extrusion-spheronizatioin. J Microencapsul 1997; 14(2): 137-153.
36. Hoffman A, Stepensky D, Lavy E, Eyal S, Klausner E, Friedman M. Pharmacokinetic and pharmacodynamic aspects of gastroretentive dosage forms. Int J Pharm 2004; 277(1-2): 141-153.
37. th ed. BI Waverly Pvt. Ltd; 1999.
38. Lee JH, Park TG, Choi HK. Development of oral drug delivery system using floating microspheres. J Microencapsul 1999; 16(6): 715-729.
39. USP 26, NF 21. Asian Edition. United states Pharmacopoeial Convention Inc; 2003.
40. James. E. Polli, G. Singh Rekhi, Vinod P. Shah. Methods to compare dissolution profiles. Drug Information Journal 1996; 30:1113-1120.
41. O'Hara T, Dunne A, Butler J, Devane J. A review of methods used to compare dissolution profile data. Pharm Sci Technol Today 1998; 1(6): 214-223.
42. Freitag G. Guidelines on Dissolution Profile comparison. Drug Information Journal 2001; 35: 865-874.
43. Costa P, Sousa Lobo JM. Modeling and comparison of dissolution profiles. Euro J Pharm Sci 2001; 13: 123 - 133.
44. FDA Guidance for Industry. SUPAC-MR - Modified Release Solid Oral Dosage Forms: Scale-Up and Post Approval Changes, Center for Drug Evaluation and Research (CDER), Sept 1997.
45. th ed. John Wiley & Sons; 1996.
46. rd ed. New York: Marcel Dekker Inc; 1997. p. 610-619.