메뉴 건너뛰기




Volumn 205, Issue 12, 2009, Pages 828-837

Hepatocyte growth factor suppresses tumor cell apoptosis in nasopharyngeal carcinoma by upregulating Bcl-2 protein expression

Author keywords

Antiapoptotic Bcl 2 protein; Apoptosis; Hepatocyte growth factor (HGF); Nasopharyngeal carcinoma (NPC)

Indexed keywords

BAX PROTEIN, HUMAN; HGF PROTEIN, HUMAN; PROTEIN BAX; PROTEIN BCL 2; SCATTER FACTOR;

EID: 75549088822     PISSN: 03440338     EISSN: 16180631     Source Type: Journal    
DOI: 10.1016/j.prp.2009.06.016     Document Type: Article
Times cited : (8)

References (40)
  • 2
    • 0034129118 scopus 로고    scopus 로고
    • Recent advances in research on multistage tumorigenesis
    • Compagni A., Christofori G. Recent advances in research on multistage tumorigenesis. Br. J. Cancer 2000, 83:1-5.
    • (2000) Br. J. Cancer , vol.83 , pp. 1-5
    • Compagni, A.1    Christofori, G.2
  • 3
    • 0026722655 scopus 로고
    • Cooperative interaction between c-myc and bcl-2 proto-oncogenes
    • Fanidi A., Harrington E.A., Evan G.I. Cooperative interaction between c-myc and bcl-2 proto-oncogenes. Nature 1992, 359:554-556.
    • (1992) Nature , vol.359 , pp. 554-556
    • Fanidi, A.1    Harrington, E.A.2    Evan, G.I.3
  • 4
    • 0038620212 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase and bcl-2 expression in nasopharyngeal cancer: correlation with outcome of patients after radiotherapy
    • Jayasurya A., Dheen S.T., Yap W.M., Tan N.G., Ng Y.K., Bay B.H. Inducible nitric oxide synthase and bcl-2 expression in nasopharyngeal cancer: correlation with outcome of patients after radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 2003, 56:837-845.
    • (2003) Int. J. Radiat. Oncol. Biol. Phys. , vol.56 , pp. 837-845
    • Jayasurya, A.1    Dheen, S.T.2    Yap, W.M.3    Tan, N.G.4    Ng, Y.K.5    Bay, B.H.6
  • 5
    • 33644904995 scopus 로고    scopus 로고
    • Systemic treatment strategies and therapeutic monitoring for advanced nasopharyngeal carcinoma
    • Ma B.B., Chan A.T. Systemic treatment strategies and therapeutic monitoring for advanced nasopharyngeal carcinoma. Expert Rev. Anticancer Ther. 2006, 6:383-394.
    • (2006) Expert Rev. Anticancer Ther. , vol.6 , pp. 383-394
    • Ma, B.B.1    Chan, A.T.2
  • 9
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green D.R., Reed J.C. Mitochondria and apoptosis. Science 1998, 281:1309-1312.
    • (1998) Science , vol.281 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 10
    • 27544498809 scopus 로고    scopus 로고
    • Induction of hepatocyte growth factor/scatter factor by fibroblast clustering directly promotes tumor cell invasiveness
    • Kankuri E., Cholujova D., Comajova M., Vaheri A., Bizik J. Induction of hepatocyte growth factor/scatter factor by fibroblast clustering directly promotes tumor cell invasiveness. Cancer Res. 2005, 65:9914-9922.
    • (2005) Cancer Res. , vol.65 , pp. 9914-9922
    • Kankuri, E.1    Cholujova, D.2    Comajova, M.3    Vaheri, A.4    Bizik, J.5
  • 13
    • 0029937303 scopus 로고    scopus 로고
    • Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1
    • Wang H.G., Takayama S., Rapp U.R., Reed J.C. Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1. Proc. Natl. Acad. Sci. USA 1996, 93:7063-7068.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 7063-7068
    • Wang, H.G.1    Takayama, S.2    Rapp, U.R.3    Reed, J.C.4
  • 14
    • 0031865606 scopus 로고    scopus 로고
    • Apoptosis in nasopharyngeal carcinoma as related to histopathological characteristics and clinical stage
    • Harn H.J., Hsieh H.F., Ho L.I., Yu C.P., Chen J.H., Chiu C.C., Fan H.C., Lee W.H. Apoptosis in nasopharyngeal carcinoma as related to histopathological characteristics and clinical stage. Histopathology 1998, 33:117-122.
    • (1998) Histopathology , vol.33 , pp. 117-122
    • Harn, H.J.1    Hsieh, H.F.2    Ho, L.I.3    Yu, C.P.4    Chen, J.H.5    Chiu, C.C.6    Fan, H.C.7    Lee, W.H.8
  • 15
    • 33745222843 scopus 로고    scopus 로고
    • Systemic Bcl-2 antisense oligodeoxynucleotide in combination with cisplatin cures EBV+ nasopharyngeal carcinoma xenografts in SCID mice
    • Lacy J., Loomis R., Grill S., Srimatkandada P., Carbone R., Cheng Y.C. Systemic Bcl-2 antisense oligodeoxynucleotide in combination with cisplatin cures EBV+ nasopharyngeal carcinoma xenografts in SCID mice. Int. J. Cancer 2006, 119:309-316.
    • (2006) Int. J. Cancer , vol.119 , pp. 309-316
    • Lacy, J.1    Loomis, R.2    Grill, S.3    Srimatkandada, P.4    Carbone, R.5    Cheng, Y.C.6
  • 17
    • 0037468125 scopus 로고    scopus 로고
    • Outpatient weekly neoadjuvant chemotherapy followed by radiotherapy for advanced nasopharyngeal carcinoma: high complete response and low toxicity rates
    • Lin J.C., Jan J.S., Hsu C.Y., Jiang R.S., Wang W.Y. Outpatient weekly neoadjuvant chemotherapy followed by radiotherapy for advanced nasopharyngeal carcinoma: high complete response and low toxicity rates. Br. J. Cancer 2003, 88:187-194.
    • (2003) Br. J. Cancer , vol.88 , pp. 187-194
    • Lin, J.C.1    Jan, J.S.2    Hsu, C.Y.3    Jiang, R.S.4    Wang, W.Y.5
  • 18
    • 0012938191 scopus 로고    scopus 로고
    • Hepatocyte growth factor induces GATA-4 phosphorylation and cell survival in cardiac muscle cells
    • Kitta K., Day R.M., Kim Y., Torregroza I., Evans T., Suzuki Y.J. Hepatocyte growth factor induces GATA-4 phosphorylation and cell survival in cardiac muscle cells. J. Biol. Chem. 2003, 278:4705-4712.
    • (2003) J. Biol. Chem. , vol.278 , pp. 4705-4712
    • Kitta, K.1    Day, R.M.2    Kim, Y.3    Torregroza, I.4    Evans, T.5    Suzuki, Y.J.6
  • 20
    • 0032524104 scopus 로고    scopus 로고
    • Landscaping the cancer terrain
    • Kinzler K.W., Vogelstein B. Landscaping the cancer terrain. Science 1998, 280:1036-1037.
    • (1998) Science , vol.280 , pp. 1036-1037
    • Kinzler, K.W.1    Vogelstein, B.2
  • 22
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens L.M., Werb Z. Inflammation and cancer. Nature 2002, 420:860-867.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 23
    • 0035861553 scopus 로고    scopus 로고
    • Hepatocyte growth factor/scatter factor blocks the mitochondrial pathway of apoptosis signaling in breast cancer cells
    • Gao M., Fan S., Goldberg I.D., Laterra J., Kitsis R.N., Rosen E.M. Hepatocyte growth factor/scatter factor blocks the mitochondrial pathway of apoptosis signaling in breast cancer cells. J. Biol. Chem. 2001, 276:47257-47265.
    • (2001) J. Biol. Chem. , vol.276 , pp. 47257-47265
    • Gao, M.1    Fan, S.2    Goldberg, I.D.3    Laterra, J.4    Kitsis, R.N.5    Rosen, E.M.6
  • 24
    • 49049111271 scopus 로고    scopus 로고
    • Hepatocyte growth factor improves survival after partial hepatectomy in cirrhotic rats suppressing apoptosis of hepatocytes
    • Nishino M., Iimuro Y., Ueki T., Hirano T., Fujimoto J. Hepatocyte growth factor improves survival after partial hepatectomy in cirrhotic rats suppressing apoptosis of hepatocytes. Surgery 2008, 144:374-384.
    • (2008) Surgery , vol.144 , pp. 374-384
    • Nishino, M.1    Iimuro, Y.2    Ueki, T.3    Hirano, T.4    Fujimoto, J.5
  • 25
    • 0028796739 scopus 로고
    • Hepatocyte growth factor: a multifunctional cytokine
    • Boros P., Miller C.M. Hepatocyte growth factor: a multifunctional cytokine. Lancet 1995, 345:293-295.
    • (1995) Lancet , vol.345 , pp. 293-295
    • Boros, P.1    Miller, C.M.2
  • 26
    • 0031765105 scopus 로고    scopus 로고
    • Inhibition of mitogen-activated protein kinase activity and proliferation of an early osteoblast cell line (MBA15.4) by dexamethasone: role of protein phosphatases
    • Hulley P.A., Gordon F., Hough F.S. Inhibition of mitogen-activated protein kinase activity and proliferation of an early osteoblast cell line (MBA15.4) by dexamethasone: role of protein phosphatases. Endocrinology 1998, 139:2423-2431.
    • (1998) Endocrinology , vol.139 , pp. 2423-2431
    • Hulley, P.A.1    Gordon, F.2    Hough, F.S.3
  • 27
    • 0027397760 scopus 로고
    • Bcl-2 proto-oncogene expression in Epstein-Barr-virus-associated nasopharyngeal carcinoma
    • Lu Q.L., Elia G., Lucas S., Thomas J.A. Bcl-2 proto-oncogene expression in Epstein-Barr-virus-associated nasopharyngeal carcinoma. Int. J. Cancer 1993, 53:29-35.
    • (1993) Int. J. Cancer , vol.53 , pp. 29-35
    • Lu, Q.L.1    Elia, G.2    Lucas, S.3    Thomas, J.A.4
  • 28
    • 13844254877 scopus 로고    scopus 로고
    • Evaluation of tumor angiogenesis measured with microvessel density (MVD) as a prognostic indicator in nasopharyngeal carcinoma: results of RTOG 9505
    • Foote R.L., Weidner N., Harris J., Hammond E., Lewis J.E., Vuong T., Ang K.K., Fu K.K. Evaluation of tumor angiogenesis measured with microvessel density (MVD) as a prognostic indicator in nasopharyngeal carcinoma: results of RTOG 9505. Int. J. Radiat. Oncol. Biol. Phys. 2005, 61:745-753.
    • (2005) Int. J. Radiat. Oncol. Biol. Phys. , vol.61 , pp. 745-753
    • Foote, R.L.1    Weidner, N.2    Harris, J.3    Hammond, E.4    Lewis, J.E.5    Vuong, T.6    Ang, K.K.7    Fu, K.K.8
  • 29
    • 0038115223 scopus 로고    scopus 로고
    • HGF receptor up-regulation contributes to the angiogenic phenotype of human endothelial cells and promotes angiogenesis in vitro
    • Ding S., Merkulova-Rainon T., Han Z.C., Tobelem G. HGF receptor up-regulation contributes to the angiogenic phenotype of human endothelial cells and promotes angiogenesis in vitro. Blood 2003, 101:4816-4822.
    • (2003) Blood , vol.101 , pp. 4816-4822
    • Ding, S.1    Merkulova-Rainon, T.2    Han, Z.C.3    Tobelem, G.4
  • 31
    • 0025772343 scopus 로고
    • Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death
    • Henderson S., Rowe M., Gregory C., Croom-Carter D., Wang F., Longnecker R., Kieff E., Rickinson A. Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death. Cell 1991, 65:1107-1115.
    • (1991) Cell , vol.65 , pp. 1107-1115
    • Henderson, S.1    Rowe, M.2    Gregory, C.3    Croom-Carter, D.4    Wang, F.5    Longnecker, R.6    Kieff, E.7    Rickinson, A.8
  • 32
    • 33646125837 scopus 로고    scopus 로고
    • Differential expression of Epstein-Barr virus-encoded RNA and several tumor-related genes in various types of nasopharyngeal epithelial lesions and nasopharyngeal carcinoma using tissue microarray analysis
    • Fan S.Q., Ma J., Zhou J., Xiong W., Xiao B.Y., Zhang W.L., Tan C., Li X.L., Shen S.R., Zhou M., Zhang Q.H., Ou Y.J., Zhuo H.D., Fan S., Zhou Y.H., Li G.Y. Differential expression of Epstein-Barr virus-encoded RNA and several tumor-related genes in various types of nasopharyngeal epithelial lesions and nasopharyngeal carcinoma using tissue microarray analysis. Hum. Pathol. 2006, 37:593-605.
    • (2006) Hum. Pathol. , vol.37 , pp. 593-605
    • Fan, S.Q.1    Ma, J.2    Zhou, J.3    Xiong, W.4    Xiao, B.Y.5    Zhang, W.L.6    Tan, C.7    Li, X.L.8    Shen, S.R.9    Zhou, M.10    Zhang, Q.H.11    Ou, Y.J.12    Zhuo, H.D.13    Fan, S.14    Zhou, Y.H.15    Li, G.Y.16
  • 34
    • 0035826172 scopus 로고    scopus 로고
    • N-terminal domain of BARF1 gene encoded by Epstein-Barr virus is essential for malignant transformation of rodent fibroblasts and activation of BCL-2
    • Sheng W., Decaussin G., Sumner S., Ooka T. N-terminal domain of BARF1 gene encoded by Epstein-Barr virus is essential for malignant transformation of rodent fibroblasts and activation of BCL-2. Oncogene 2001, 20:1176-1185.
    • (2001) Oncogene , vol.20 , pp. 1176-1185
    • Sheng, W.1    Decaussin, G.2    Sumner, S.3    Ooka, T.4
  • 35
    • 33947234746 scopus 로고    scopus 로고
    • Anti-apoptotic role of TWIST and its association with Akt pathway in mediating taxol resistance in nasopharyngeal carcinoma cells
    • Zhang X., Wang Q., Ling M.T., Wong Y.C., Leung S.C., Wang X. Anti-apoptotic role of TWIST and its association with Akt pathway in mediating taxol resistance in nasopharyngeal carcinoma cells. Int. J. Cancer 2007, 120:1891-1898.
    • (2007) Int. J. Cancer , vol.120 , pp. 1891-1898
    • Zhang, X.1    Wang, Q.2    Ling, M.T.3    Wong, Y.C.4    Leung, S.C.5    Wang, X.6
  • 36
    • 37349036435 scopus 로고    scopus 로고
    • Locally overexpressing hepatocyte growth factor prevents post-ischemic heart failure by inhibition of apoptosis via calcineurin-mediated pathway and angiogenesis
    • Guo Y., He J., Wu J., Yang L., Dai S., Tan X., Liang L. Locally overexpressing hepatocyte growth factor prevents post-ischemic heart failure by inhibition of apoptosis via calcineurin-mediated pathway and angiogenesis. Arch. Med. Res. 2008, 39:179-188.
    • (2008) Arch. Med. Res. , vol.39 , pp. 179-188
    • Guo, Y.1    He, J.2    Wu, J.3    Yang, L.4    Dai, S.5    Tan, X.6    Liang, L.7
  • 37
    • 0032004759 scopus 로고    scopus 로고
    • Determination of Epstein-Barr virus association with B-cell lymphomas in Japan: study of 72 cases - in situ hybridization, polymerase chain reaction, immunohistochemical studies
    • Hirose Y., Masaki Y., Sasaki K., Ogawa Y., Takeshita S., Fukutoku M., Sugai S., Takiguchi T. Determination of Epstein-Barr virus association with B-cell lymphomas in Japan: study of 72 cases - in situ hybridization, polymerase chain reaction, immunohistochemical studies. Int. J. Hematol. 1998, 67:165-174.
    • (1998) Int. J. Hematol. , vol.67 , pp. 165-174
    • Hirose, Y.1    Masaki, Y.2    Sasaki, K.3    Ogawa, Y.4    Takeshita, S.5    Fukutoku, M.6    Sugai, S.7    Takiguchi, T.8
  • 38
    • 7444246305 scopus 로고    scopus 로고
    • Hepatocyte growth factor prevents ventricular remodeling and dysfunction in mice via Akt pathway and angiogenesis
    • Wang Y., Ahmad N., Wani M.A., Ashraf M. Hepatocyte growth factor prevents ventricular remodeling and dysfunction in mice via Akt pathway and angiogenesis. J. Mol. Cell Cardiol. 2004, 37:1041-1052.
    • (2004) J. Mol. Cell Cardiol. , vol.37 , pp. 1041-1052
    • Wang, Y.1    Ahmad, N.2    Wani, M.A.3    Ashraf, M.4
  • 39
    • 34548062300 scopus 로고    scopus 로고
    • Expression of hepatocyte growth factor/c-Met system in nasopharyngeal carcinoma and its biological significance
    • Li Z., Lin S.X., Liang H.Z., He J.H. Expression of hepatocyte growth factor/c-Met system in nasopharyngeal carcinoma and its biological significance. Zhonghua Bing Li Xue Za Zhi 2005, 34:75-79.
    • (2005) Zhonghua Bing Li Xue Za Zhi , vol.34 , pp. 75-79
    • Li, Z.1    Lin, S.X.2    Liang, H.Z.3    He, J.H.4
  • 40
    • 53449100203 scopus 로고    scopus 로고
    • ApoG2, a novel inhibitor of antiapoptotic Bcl-2 family proteins, induces apoptosis and suppresses tumor growth in nasopharyngeal carcinoma xenografts
    • Hu Z.Y., Zhu X.F., Zhong Z.D., Sun J., Wang J., Yang D., Zeng Y.X. ApoG2, a novel inhibitor of antiapoptotic Bcl-2 family proteins, induces apoptosis and suppresses tumor growth in nasopharyngeal carcinoma xenografts. Int. J. Cancer 2008, 123:2418-2429.
    • (2008) Int. J. Cancer , vol.123 , pp. 2418-2429
    • Hu, Z.Y.1    Zhu, X.F.2    Zhong, Z.D.3    Sun, J.4    Wang, J.5    Yang, D.6    Zeng, Y.X.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.