Genome-wide scan for familial nasopharyngeal carcinoma reveals evidence of linkage to chromosome 4

Nature Genetics

Volumn 31, Issue 4, 2002, Pages 395-399

  Feng, Bing Jian ^a   Huang, Wei ^b,e   Shugart, Yin Yao ^c   Lee, Ming K ^d   Zhang, Feng ^a   Xia, Jian Chuan ^a   Wang, Hui Yun ^a   Huang, Teng Bo ^a   Jian, Shao Wen ^a   Huang, Ping ^a   Feng, Qi Sheng ^a   Huang, Li Xi ^a   Yu, Xing Juan ^a   Li, Duang ^a   Chen, Li Zheng ^a   Jia, Wei Hua ^a   Fang, Yan ^a   Huang, Hui Ming ^a   Liu, Xiao Ming ^b   Zhao, Yan ^b   Liu, Wang Qing ^b   Deng, Mang Quan ^a   Hu, Wei Han ^a   Wu, Shao Xiong ^a   Mo, Hao Yuan ^a   Hong, Ming Fang ^a   King, Mary Claire ^d   Chen, Zhu ^b   Zeng, Yi Xin ^a   more..

^a SUN YAT SEN UNIVERSITY   (China)

^b CHINESE NATIONAL HUMAN GENOME CENTER AT SHANGHAI   (China)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

^e SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS ANTIBODY;

ANTIBODY TITER; ARTICLE; ASIAN; CANCER INCIDENCE; CANCER RISK; CHINA; CHROMOSOME 4; DNA FLANKING REGION; EPSTEIN BARR VIRUS; FAMILIAL CANCER; GENE LOCUS; GENE MAPPING; GENETIC LINKAGE; GENETIC MARKER; GENETIC PREDISPOSITION; GENOME; HEREDITY; HUMAN; NASOPHARYNX CARCINOMA; PRIORITY JOURNAL;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; CARCINOMA; CHINA; CHROMOSOMES, HUMAN, PAIR 12; CHROMOSOMES, HUMAN, PAIR 4; FEMALE; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; GENOME, HUMAN; HERPESVIRUS 4, HUMAN; HUMANS; LINKAGE (GENETICS); MALE; MIDDLE AGED; NASOPHARYNGEAL NEOPLASMS; PEDIGREE; RECOMBINATION, GENETIC;

HUMAN HERPESVIRUS 4;

EID: 0036699967     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng932     Document Type: Article

References (24)

1. Vokes, E.E., Liebowitz, D.N. & Weichselbaum, R.R. Nasopharyngeal carcinoma. Lancet 350, 1087-1091 (1997).
2. Huang, T.B. & Min, H.Q. in Nasopharyngeal Carcinoma Research (eds Min, H.Q., Wang, H.M., Zhang, E.P. & Hong, M.H) 6-12 (Guangdong Science and Technology Press, Guangzhou, China, 1998).
3. Chen, D.L. & Huang, T.B. A case-control study of risk factors of nasopharyngeal carcinoma. Cancer Lett. 117, 17-22 (1997).
4. Fischer, A., Fisher, G.O. & Cooper, E. Familial nasopharyngeal carcinoma. Pathology 16, 23-24 (1984).
5. Nevo, S., Mexer, W. & Altman, M. Carcinoma of nasopharynx in twins. Cancer 28, 807-809 (1997).
6. Chan, S.H. Aetiology of nasopharyngeal carcinoma. Ann. Acad. Med. Singapore 19, 201-207 (1990).
7. Lu, S.J. et al. Linkage of a nasopharyngeal carcinoma susceptibility locus to the HLA region. Nature 346, 470-471 (1990).
8. Ooi, E.E., Ren, E.C. & Chan, S.H. Association between microsatellites within the human MHC and nasopharyngeal carcinoma. Int. J. Cancer 74, 229-232 (1997).
9. Hall, J.M. et al. Linkage of early-onset familial breast cancer to chromosome 17q21. Science 250, 1684-1689 (1990).
10. Smith, J.R. et al. Major susceptibility locus for prostate cancer on chromosome 1 suggested by a genome-wide search. Science 274, 137-274 (1996).
11. Dib, C. et al. A comprehensive genetic map of the human genome based on 5264 microsatellites. Nature 380, 152-154 (1996).
12. Kruglyak, L., Daly, M.J., Reeve-Daly, M.P. & Lander, E.S. Parametric and nonparametric linkage analysis: unified multipoint approach. Am. J. Hum. Genet. 58, 1347-1363 (1996).
13. Lathrop, G.M. & Lalouel, J.M. Easy calculations of lod scores and genetic risks on small computers. Am. J. Hum. Genet. 36, 460-465 (1984).
14. Lathrop, G.M., Lalouel, J.M., Julier, C. & Ott, J. Strategies for multilocus analysis in humans. Proc. Natl Acad. Sci. USA 81, 3443-3446 (1984).
15. Lathrop, G.M., Lalouel, J.M. & White, R.L. Construction of human linkage maps: likelihood calculations for multilocus linkage analysis. Genet. Epidemiol. 3, 39-52 (1986).
16. Cottingham, R.W. Jr., Idury, R.M. and Schaffer, A.A. Faster sequential genetic linkage computations. Am. J. Hum. Genet. 53, 252-263 (1993).
17. Schaffer, A.A., Gupta, S.K., Shriram, K. & Cottingham, R.W. Jr. Avoiding recomputation in linkage analysis. Hum. Hered. 44, 225-237 (1994).
18. Olson, J.M. A general conditional-logistic model for affected-relative-pair linkage studies. Am. J. Hum. Genet. 65, 1760-1769 (1999).
19. Goddard, K.A., Witte, J.S., Suarez, B.K., Catalona, W.J. & Olson, J.M. Model-free linkage analysis with covariates confirms linkage of prostate cancer to chromosomes 1 and 4. Am. J. Hum. Genet. 68, 1197-1206 (2001).
20. Self, S.G. & Liang, K.Y. Asymptotic properties of maximum likelihood estimators and likelihood ratio tests under non-standard conditions. J. Am. Stat. Assoc. 82, 605-610 (1987).
21. Ott, J. Linkage probability and its approximate confidence interval under possible heterogeneity. Genet. Epidemiol. 1 (Suppl.), 251-257 (1986).
22. Sobel, E. & Lange, K. Descent graphs in pedigree analysis: applications to haplotyping, location scores, and marker-sharing statistics. Am. J. Hum. Genet. 58, 1323-1337 (1996).
23. Henderson, B.E. et al. Risk factors associated with nasopharyngeal carcinoma. N. Engl. J. Med. 295, 1101-1106 (1976).
24. Broman, K.W., Murray, J.C., Sheffield, V.C., White, R.L. & Weber, J.L. Comprehensive human genetic map: individual and sex-specific variation in recombination. Am. J. Hum. Genet. 63, 861-869 (1998).