An electron paramagnetic resonance study of the affinity of nitrite for methemoglobin

Nitric Oxide - Biology and Chemistry

Volumn 22, Issue 2, 2010, Pages 149-154

  Goetz, Bradley I ^a   Shields, Howard W ^a   Basu, Swati ^a   Wang, Pamela ^a   King, S Bruce ^a   Hogg, Neil ^b   Gladwin, Mark T ^c   Kim Shapiro, Daniel B ^a  

^a WAKE FOREST UNIVERSITY   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

^c UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

Electron paramagnetic resonance; Hemoglobin; Nitric oxide; Nitrite

Indexed keywords

CARBONATE DEHYDRATASE; HEME; METHEMOGLOBIN; NITRIC OXIDE; NITRITE;

ARTICLE; BINDING AFFINITY; CHEMICAL REACTION; CHEMICAL STRUCTURE; DISSOCIATION CONSTANT; ELECTRON SPIN RESONANCE; PH MEASUREMENT; PRIORITY JOURNAL;

ELECTRON SPIN RESONANCE SPECTROSCOPY; METHEMOGLOBIN; NITRITES;

EID: 75449116509     PISSN: 10898603     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.niox.2009.10.009     Document Type: Article

References (34)

1. Cosby K., Partovi K.S., Crawford J.H., Patel R.P., Reiter C.D., Martyr S., Yang B.K., Waclawiw M.A., Zalos G., Xu X.L., Huang K.T., Shields H., Kim-Shapiro D.B., Schechter A.N., Cannon R.O., and Gladwin M.T. Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation. Nature Medicine 9 (2003) 1498-1505
2. Shiva S., Huang Z., Grubina R., Sun J.H., Ringwood L.A., MacArthur P.H., Xu X.L., Murphy E., Darley-Usmar V.M., and Gladwin M.T. Deoxymyoglobin is a nitrite reductase that generates nitric oxide and regulates mitochondrial respiration. Circulation Research 100 (2007) 654-661
3. Li H.T., Samouilov A., Liu X.P., and Zweier J.L. Characterization of the magnitude and kinetics of xanthine oxidase-catalyzed nitrite reduction - evaluation of its role in nitric oxide generation in anoxic tissues. Journal of Biological Chemistry 276 (2001) 24482-24489
4. Li H., Cui H., Kundu T.K., Alzawahra W., and Zweier J.L. Nitric oxide production from nitrite occurs primarily in tissues not in the blood: critical role of xanthine oxidase and aldehyde oxidase. Journal of Biological Chemistry 283 (2008) 17855-17863
5. Webb A.J., Milsom A.B., Rathod K.S., Chu W.L., Qureshi S., Lovell M.J., Lecomte F.M.J., Perrett D., Raimondo C., Khoshbin E., Ahmed Z., Uppal R., Benjamin N., Hobbs A.J., and Ahluwalia A. Mechanisms underlying erythrocyte and endothelial nitrite reduction to nitric oxide in hypoxia role for xanthine oxidoreductase and endothelial nitric oxide synthase. Circulation Research 103 (2008) 957-964
6. Zweier J.L., Wang P.H., Samouilov A., and Kuppusamy P. Enzyme-independent formation of nitric-oxide in biological tissues. Nature Medicine 1 (1995) 804-809
7. Millar T.M., Stevens C.R., Benjamin N., Eisenthal R., Harrison R., and Blake D.R. Xanthine oxidoreductase catalyses the reduction of nitrates and nitrite to nitric oxide under hypoxic conditions. FEBS Letters 427 (1998) 225-228
8. Gautier C., van Faassen E., Mikula I., Martasek P., and Slama-Schwok A. Endothelial nitric oxide synthase reduces nitrite anions to NO under anoxia. Biochemical and Biophysical Research Communications 341 (2006) 816-821
9. Vanin A.F., Bevers L.M., Slama-Schwok A., and Van Faassen E.E. Nitric oxide synthase reduces nitrite to NO under anoxia. Cellular and Molecular Life Sciences 64 (2007) 96-103
10. Kozlov A.V., Staniek K., and Nohl H. Nitrite reductase activity is a novel function of mammalian mitochondria. FEBS Letters 454 (1999) 127-130
11. Castello P.R., David P.S., McClure T., Crook Z., and Poyton R.O. Mitochondrial cytochrome oxidase produces nitric oxide under hypoxic conditions: implications for oxygen sensing and hypoxic signaling in eukaryotes. Cell Metabolism 3 (2006) 277-287
12. Castello P.R., Woo D.K., Ball K., Wojcik J., Liu L., and Poyton R.O. Oxygen-regulated isoforms of cytochrome c oxidase have differential effects on its nitric oxide production and on hypoxic signaling. Proceedings of the National Academy ofSciences of the United States of America 105 (2008) 8203-8208
13. Basu S., Azarova N.A., Font M.D., King S.B., Hogg N., Gladwin M.T., Shiva S., and Kim-Shapiro D.B. Nitrite reductase activity of cytochrome c. Journal of Biological Chemistry 283 (2008) 32590-32597
14. Chen Y.R., Chen L.C., Liu X., Li H.T., Zweier J.L., and Mason M.P. Involvement of protein radical, protein aggregation, and effects on NO metabolism in the hypochlorite-mediated oxidation of mitochondrial cytochrome c. Free Radical Biology & Medicine 37 (2004) 1591-1603
15. Crawford J.H., Isbell T.S., Huang Z., Shiva S., Chacko B.K., Schechter A.N., Darley-Usmar V.M., Kerby J.D., Lang J.D., Kraus D., Ho C., Gladwin M.T., and Patel R.P. Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation. Blood 107 (2006) 566-574
16. Isbell T.S., Gladwin M.T., and Patel R.P. Hemoglobin oxygen fractional saturation regulates nitrite-dependent vasodilation of aortic ring bioassays. American Journal of Physiology. Heart and Circulatory Physiology 293 (2007) H2565-H2572
17. Yu B., Raher M.J., Volpato G.P., Bloch K.D., Ichinose F., and Zapol W.M. Inhaled nitric oxide enables artificial blood transfusion without hypertension. Circulation 117 (2008) 1982-1990
18. Dejam A., Hunter C.J., Tremonti C., Pluta R.M., Hon Y.Y., Grimes G., Partovi K., Pelletier M.M., Oldfield E.H., Cannon III R.O., Schechter A.N., and Gladwin M.T. Nitrite infusion in humans and nonhuman primates. Endocrine effects, pharmacokinetics, and tolerance formation. Circulation 116 (2007) 1821-1831
19. Doyle M.P., and Hoekstra J.W. Oxidation of nitrogen-oxides by bound dioxygen in hemoproteins. Journal of Inorganic Biochemistry 14 (1981) 351-358
20. Eich R.F., Li T.S., Lemon D.D., Doherty D.H., Curry S.R., Aitken J.F., Mathews A.J., Johnson K.A., Smith R.D., Phillips G.N., and Olson J.S. Mechanism of NO-induced oxidation of myoglobin and hemoglobin. Biochemistry 35 (1996) 6976-6983
21. Herold S., Exner M., and Nauser T. Kinetic and mechanistic studies of the NO center dot-mediated oxidation of oxymyoglobin and oxyhemoglobin. Biochemistry 40 (2001) 3385-3395
22. Jeffers A., Xu X.L., Huang K.T., Cho M., Hogg N., Patel R.P., and Kim-Shapiro D.B. Hemoglobin mediated nitrite activation of soluble guanylyl cyclase. Comparative Biochemistry and Physiology A, Molecular & Integrative Physiology 142 (2005) 130-135
23. Robinson J.M., and Lancaster J.R. Hemoglobin-mediated, hypoxia-induced vasodilation via nitric oxide - mechanism(s) and physiologic versus pathophysiologic relevance. American Journal of Respiratory Cell and Molecular Biology 32 (2005) 257-261
24. 3 by a concerted nitrite reductase and anhydrase activity of hemoglobin. Nature Chemical Biology 3 (2007) 785-794
25. Fernandez B.O., and Ford P.C. Nitrite catalyzes ferriheme protein reductive nitrosylation. Journal of the American Chemical Society 125 (2003) 10510-10511
26. Navati M.S., and Friedman J.M. Reactivity of glass-embedded met hemoglobin derivatives toward external NO: implications for nitrite-mediated production of bioactive NO. Journal of the American Chemical Society 131 (2009) 12273-12279
27. He C.M., and Knipp M. Formation of nitric oxide from nitrite by the ferriheme b protein nitrophorin 7. Journal of the American Chemical Society 131 (2009) 12042-12043
28. Yi J., Safo M.K., and Richter-Addo G.B. The nitrite anion binds to human hemoglobin via the uncommon O-nitrito mode. Biochemistry 47 (2008) 8247-8249
29. Schwab D.E., Stamler J.S., and Singel D.J. Nitrite-methemoglobin inadequate for hypoxic vasodilation. Nature Chemical Biology 5 (2009) 366
30. Goetz B.I., Wang P., Shields H.W., Basu S., Grubina R., Huang J., Conradie J., Huang Z., Jeffers A., Jiang A., He X., Azarov I., Seibert R., Mehta A., Patel R., King S.B., Ghosh A., Hogg N., Gladwin M.T., and Kim-Shapiro D.B. Nitrite-methemoglobin inadequate for hypoxic vasodilation Reply. Nature Chemical Biology 5 (2009) 367
31. Day E.P., Peterson J., Bonvoisin J.J., Young L.J., Wilkerson J.O., and Siegel L.M. Magnetization of the sulfite and nitrite complexes of oxidized sulfite and nitrite reductases - electron-paramagnetic-res silent spin S = 1/2 states. Biochemistry 27 (1988) 2126-2132
32. Young L.J., and Siegel L.M. On the reaction of ferric heme-proteins with nitrite and sulfite. Biochemistry 27 (1988) 2790-2800
33. Rodkey F.L. Mechanism for conversion of oxyhemoglobin to methemoglobin by nitrite. Clinical Chemistry 22 (1976) 1986-1990
34. Novozhilova I.V., Coppens P., Lee J., Richter-Addo G.B., and Bagley K.A. Experimental and density functional theoretical investigations of linkage isomerism in six-coordinate {FeNO}(6) iron porphyrins with axial nitrosyl and nitro ligands. Journal of the American Chemical Society 128 (2006) 2093-2104