Involvement of protein radical, protein aggregation, and effects on NO metabolism in the hypochlorite-mediated oxidation of mitochondrial cytochrome c

Free Radical Biology and Medicine

Volumn 37, Issue 10, 2004, Pages 1591-1603

  Chen, Yeong Renn ^a   Chen, Chwen Lih ^a   Liu, Xiaoping ^a   Li, Haitao ^a   Zweier, Jay L ^a   Mason, Ronald P ^b  

^a OHIO STATE UNIVERSITY   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Cytochrome c; Free radicals; Hypochlorite; Nitric oxide metabolism; Protein aggregates; Protein radical

Indexed keywords

2 METHYL 2 NITROSOPROPANE; 5,5 DIMETHYL 1 PYRROLINE 1 OXIDE; CYTOCHROME C; HYPOCHLORITE; LYSINE; NITRIC OXIDE; NITRONE DERIVATIVE; PROPANE; REACTIVE OXYGEN METABOLITE; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CONCENTRATION RESPONSE; ELECTRON SPIN RESONANCE; ENZYME REGULATION; HYPOTHESIS; MITOCHONDRION; NITRATION; OXIDATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN FUNCTION; WESTERN BLOTTING;

ANIMALS; CYCLIC N-OXIDES; CYTOCHROMES C; ELECTRON SPIN RESONANCE SPECTROSCOPY; HUMANS; HYPOCHLOROUS ACID; NITRIC OXIDE; NITRITES; OXIDATION-REDUCTION; PROTEIN BINDING; REACTIVE OXYGEN SPECIES; TYROSINE;

EID: 5344228345     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2004.07.013     Document Type: Article

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