The polyhydroxylated fullerene derivative C60(OH)24 protects mice from ionizing-radiation-induced immune and mitochondrial dysfunction

Toxicology and Applied Pharmacology

Volumn 243, Issue 1, 2010, Pages 27-34

  Cai, Xiaoqing ^a   Hao, Jiejie ^b,c   Zhang, Xiaoyong ^a   Yu, Bozhang ^a   Ren, Jinming ^b   Luo, Cheng ^d   Li, Qingnuan ^a   Huang, Qing ^a   Shi, Xianglin ^e   Li, Wenxin ^a   Liu, Jiankang ^d,e  

^a SHANGHAI INSTITUTE OF APPLIED PHYSICS   (China)

^b Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

^c OCEAN UNIVERSITY OF CHINA   (China)

^d BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^e UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Antioxidant; Apoptosis; Mortality; Oxidative damage; Radioprotection; Reactive oxygen species

Indexed keywords

COBALT 60; FULLERENE DERIVATIVE; GLUTATHIONE; HYDROGEN PEROXIDE; MALONALDEHYDE; RADIOPROTECTIVE AGENT; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOCHEMISTRY; CELL PROLIFERATION; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG MECHANISM; DRUG SYNTHESIS; GAMMA RADIATION; IMMUNOPATHOLOGY; IONIZING RADIATION; LIVER; LIVER MITOCHONDRION; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MORTALITY; MOUSE; NONHUMAN; OXIDATIVE STRESS; RADIATION DOSE; RADIATION PROTECTION; SPLEEN; SPLEEN CELL; SURVIVAL;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; FULLERENES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MITOCHONDRIA; MITOCHONDRIA, LIVER; RADIATION INJURIES, EXPERIMENTAL; RADIATION-PROTECTIVE AGENTS; REACTIVE OXYGEN SPECIES; SPLEEN;

ANIMALIA; MUS;

EID: 75149192999     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2009.11.009     Document Type: Article

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