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Volumn 17, Issue 1, 2010, Pages 44-50

Gastrointestinal peptides and bone health

Author keywords

Anorexia; Bone; Diabetes; Gastrointestinal peptide; Obesity

Indexed keywords

1 (2,3 DIHYDRO 1 METHYL 2 OXO 5 PHENYL 1H 1,4 BENZODIAZEPIN 3 YL) 3 (3 METHYLPHENYL)UREA; ADRENOMEDULLIN; AMYLIN; AMYLIN DERIVATIVE; CHOLECYSTOKININ; DEVAZEPIDE; GASTRIC INHIBITORY POLYPEPTIDE; GASTROINTESTINAL POLYPEPTIDE; GHRELIN; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 2; PANCREAS HORMONE; PANCREAS POLYPEPTIDE; PEPTIDE YY; PRAMLINTIDE; PREPTIN; SEROTONIN; SEROTONIN UPTAKE INHIBITOR; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 75149144404     PISSN: 1752296X     EISSN: None     Source Type: Journal    
DOI: 10.1097/MED.0b013e3283344a05     Document Type: Review
Times cited : (30)

References (84)
  • 1
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima M, Hosoda H, Date Y, et al. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 1999; 402:656-660.
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3
  • 2
    • 17944379112 scopus 로고    scopus 로고
    • Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans
    • Ariyasu H, Takaya K, Tagami T, et al. Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans. J Clinical Endocrinol Metab 2001; 86:4753-4758.
    • (2001) J Clinical Endocrinol Metab , vol.86 , pp. 4753-4758
    • Ariyasu, H.1    Takaya, K.2    Tagami, T.3
  • 3
    • 0035433977 scopus 로고    scopus 로고
    • A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans
    • Cummings DE, Purnell JQ, Frayo RS, et al. A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes 2001; 50:1714-1719.
    • (2001) Diabetes , vol.50 , pp. 1714-1719
    • Cummings, D.E.1    Purnell, J.Q.2    Frayo, R.S.3
  • 4
  • 7
    • 13444270393 scopus 로고    scopus 로고
    • Ghrelin regulates proliferation and differentiation of osteoblastic cells
    • Maccarinelli G, Sibilia V, Torsello A, et al. Ghrelin regulates proliferation and differentiation of osteoblastic cells. J Endocrinol 2005; 184:249-256.
    • (2005) J Endocrinol , vol.184 , pp. 249-256
    • MacCarinelli, G.1    Sibilia, V.2    Torsello, A.3
  • 8
    • 23844447768 scopus 로고    scopus 로고
    • Ghrelin stimulates proliferation and differentiation and inhibits apoptosis in osteoblastic MC3T3-E1 cells
    • Kim SW, Her SJ, Park SJ, et al. Ghrelin stimulates proliferation and differentiation and inhibits apoptosis in osteoblastic MC3T3-E1 cells. Bone 2005; 37:359-369.
    • (2005) Bone , vol.37 , pp. 359-369
    • Kim, S.W.1    Her, S.J.2    Park, S.J.3
  • 9
    • 31544452274 scopus 로고    scopus 로고
    • Ghrelin and unacylated ghrelin stimulate human osteoblast growth via mitogen-activated protein kinase (MAPK)/phosphoinositide 3-kinase (PI3K) pathways in the absence of GHS-R1a
    • Delhanty PJ, van der Eerden BC, van der Velde M, et al. Ghrelin and unacylated ghrelin stimulate human osteoblast growth via mitogen-activated protein kinase (MAPK)/phosphoinositide 3-kinase (PI3K) pathways in the absence of GHS-R1a. J Endocrinol 2006; 188:37-47.
    • (2006) J Endocrinol , vol.188 , pp. 37-47
    • Delhanty, P.J.1    Van Der Eerden, B.C.2    Van Der Velde, M.3
  • 10
    • 63449108642 scopus 로고    scopus 로고
    • Ghrelin stimulates proliferation of human osteoblastic TE85 cells via NO/cGMP signaling pathway
    • Wang DH, Hu YS, Du JJ, et al. Ghrelin stimulates proliferation of human osteoblastic TE85 cells via NO/cGMP signaling pathway. Endocrine 2009; 35:112-117.
    • (2009) Endocrine , vol.35 , pp. 112-117
    • Wang, D.H.1    Hu, Y.S.2    Du, J.J.3
  • 11
    • 0242580169 scopus 로고    scopus 로고
    • Deletion of ghrelin impairs neither growth nor appetite
    • Sun Y, Ahmed S, Smith RG. Deletion of ghrelin impairs neither growth nor appetite. Mol Cell Biol 2003; 23:7973-7981.
    • (2003) Mol Cell Biol , vol.23 , pp. 7973-7981
    • Sun, Y.1    Ahmed, S.2    Smith, R.G.3
  • 12
    • 1842480284 scopus 로고    scopus 로고
    • Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor
    • Sun Y, Wang P, Zheng H, Smith RG. Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor. Proc Natl Acad Sci U S A 2004; 101:4679-4684.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 4679-4684
    • Sun, Y.1    Wang, P.2    Zheng, H.3    Smith, R.G.4
  • 13
    • 18244391222 scopus 로고    scopus 로고
    • Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion
    • Shiiya T, Nakazato M, Mizuta M, et al. Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion. J Clin Endocrinol Metab 2002; 87:240-244.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 240-244
    • Shiiya, T.1    Nakazato, M.2    Mizuta, M.3
  • 15
    • 42049093212 scopus 로고    scopus 로고
    • Prognostic indicators of changes in bone density measures in adolescent girls with anorexia nervosa-II
    • Misra M, Prabhakaran R, Miller KK, et al. Prognostic indicators of changes in bone density measures in adolescent girls with anorexia nervosa-II. J Clin Endocrinol Metab 2008; 93:1292-1297.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 1292-1297
    • Misra, M.1    Prabhakaran, R.2    Miller, K.K.3
  • 16
    • 67649425774 scopus 로고    scopus 로고
    • Relationships of acylated and desacyl ghrelin levels to bone mineralization in obese children and adolescents
    • Pacifico L, Anania C, Poggiogalle E, et al. Relationships of acylated and desacyl ghrelin levels to bone mineralization in obese children and adolescents. Bone 2009; 45:274-279.
    • (2009) Bone , vol.45 , pp. 274-279
    • Pacifico, L.1    Anania, C.2    Poggiogalle, E.3
  • 17
    • 64549099834 scopus 로고    scopus 로고
    • Effect of pubertal development and physical activity on plasma ghrelin concentration in boys
    • Jurimae J, Cicchella A, Tillmann V, et al. Effect of pubertal development and physical activity on plasma ghrelin concentration in boys. J Endocrinol Invest 2009; 32:18-22.
    • (2009) J Endocrinol Invest , vol.32 , pp. 18-22
    • Jurimae, J.1    Cicchella, A.2    Tillmann, V.3
  • 18
    • 40249089759 scopus 로고    scopus 로고
    • Change in adipocytokines and ghrelin with menopause
    • Sowers MR, Wildman RP, Mancuso P, et al. Change in adipocytokines and ghrelin with menopause. Maturitas 2008; 59:149-157.
    • (2008) Maturitas , vol.59 , pp. 149-157
    • Sowers, M.R.1    Wildman, R.P.2    Mancuso, P.3
  • 19
    • 0027448057 scopus 로고
    • The pancreatic polypeptide (PP-fold) family: Gastrointestinal, vascular, and feeding behavioral implications
    • Hazelwood RL. The pancreatic polypeptide (PP-fold) family: gastrointestinal, vascular, and feeding behavioral implications. Proc Soc Exp Biol Med 1993; 202:44-63.
    • (1993) Proc Soc Exp Biol Med , vol.202 , pp. 44-63
    • Hazelwood, R.L.1
  • 20
    • 35648985690 scopus 로고    scopus 로고
    • Peptide YY regulates bone turnover in rodents
    • Wortley KE, Garcia K, Okamoto H, et al. Peptide YY regulates bone turnover in rodents. Gastroenterology 2007; 133:1534-1543.
    • (2007) Gastroenterology , vol.133 , pp. 1534-1543
    • Wortley, K.E.1    Garcia, K.2    Okamoto, H.3
  • 21
    • 0036212496 scopus 로고    scopus 로고
    • Hypothalamic Y2 receptors regulate bone formation
    • Baldock PA, Sainsbury A, Couzens M, et al. Hypothalamic Y2 receptors regulate bone formation. J Clin Invest 2002; 109:915-921.
    • (2002) J Clin Invest , vol.109 , pp. 915-921
    • Baldock, P.A.1    Sainsbury, A.2    Couzens, M.3
  • 22
    • 0041859261 scopus 로고    scopus 로고
    • Inhibition of food intake in obese subjects by peptide YY3-36
    • Batterham RL, Cohen MA, Ellis SM, et al. Inhibition of food intake in obese subjects by peptide YY3-36. N Engl J Med 2003; 349:941-948.
    • (2003) N Engl J Med , vol.349 , pp. 941-948
    • Batterham, R.L.1    Cohen, M.A.2    Ellis, S.M.3
  • 23
    • 0036861322 scopus 로고    scopus 로고
    • Relationships among body mass, its components, and bone
    • Reid IR. Relationships among body mass, its components, and bone. Bone 2002; 31:547-555.
    • (2002) Bone , vol.31 , pp. 547-555
    • Reid, I.R.1
  • 24
    • 17844368601 scopus 로고    scopus 로고
    • Ghrelin, peptide YY, glucose-dependent insulinotropic polypeptide, and hunger responses to a mixed meal in anorexic, obese, and control female adolescents
    • Stock S, Leichner P, Wong AC, et al. Ghrelin, peptide YY, glucose-dependent insulinotropic polypeptide, and hunger responses to a mixed meal in anorexic, obese, and control female adolescents. J Clin Endocrinol Metab 2005; 90:2161-2168.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 2161-2168
    • Stock, S.1    Leichner, P.2    Wong, A.C.3
  • 25
    • 44949152383 scopus 로고    scopus 로고
    • Peptide YY (PYY) levels and bone mineral density (BMD) in women with anorexia nervosa
    • Utz AL, Lawson EA, Misra M, et al. Peptide YY (PYY) levels and bone mineral density (BMD) in women with anorexia nervosa. Bone 2008; 43:135-139.
    • (2008) Bone , vol.43 , pp. 135-139
    • Utz, A.L.1    Lawson, E.A.2    Misra, M.3
  • 26
    • 67349191036 scopus 로고    scopus 로고
    • Peptide YY in adolescent athletes with amenorrhea, eumenorrheic athletes and nonathletic controls
    • Russell M, Stark J, Nayak S, et al. Peptide YY in adolescent athletes with amenorrhea, eumenorrheic athletes and nonathletic controls. Bone 2009; 45:104-109.
    • (2009) Bone , vol.45 , pp. 104-109
    • Russell, M.1    Stark, J.2    Nayak, S.3
  • 27
    • 47649092761 scopus 로고    scopus 로고
    • Pancreatic polypeptide is secreted from and controls differentiation through its specific receptors in osteoblastic MC3T3-E1 cells
    • Hosaka H, Nagata A, Yoshida T, et al. Pancreatic polypeptide is secreted from and controls differentiation through its specific receptors in osteoblastic MC3T3-E1 cells. Peptides 2008; 29:1390-1395.
    • (2008) Peptides , vol.29 , pp. 1390-1395
    • Hosaka, H.1    Nagata, A.2    Yoshida, T.3
  • 28
    • 0042592910 scopus 로고    scopus 로고
    • Synergistic effects of Y2 and Y4 receptors on adiposity and bone mass revealed in double knockout mice
    • Sainsbury A, Baldock PA, Schwarzer C, et al. Synergistic effects of Y2 and Y4 receptors on adiposity and bone mass revealed in double knockout mice. Mol Cell Biol 2003; 23:5225-5233.
    • (2003) Mol Cell Biol , vol.23 , pp. 5225-5233
    • Sainsbury, A.1    Baldock, P.A.2    Schwarzer, C.3
  • 29
    • 18044386744 scopus 로고    scopus 로고
    • LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development
    • Gong Y, Slee RB, Fukai N, et al. LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development. Cell 2001; 107:513-523.
    • (2001) Cell , vol.107 , pp. 513-523
    • Gong, Y.1    Slee, R.B.2    Fukai, N.3
  • 30
    • 0037118285 scopus 로고    scopus 로고
    • High bone density due to a mutation in LDLreceptor-related protein 5
    • Boyden LM, Mao J, Belsky J, et al. High bone density due to a mutation in LDLreceptor-related protein 5. N Engl J Med 2002; 346:1513-1521.
    • (2002) N Engl J Med , vol.346 , pp. 1513-1521
    • Boyden, L.M.1    Mao, J.2    Belsky, J.3
  • 31
    • 0036138175 scopus 로고    scopus 로고
    • A mutation in the LDL receptorrelated protein 5 gene results in the autosomal dominant high-bone-mass trait
    • Little RD, Carulli JP, Del Mastro RG, et al. A mutation in the LDL receptorrelated protein 5 gene results in the autosomal dominant high-bone-mass trait. Am J Hum Genet 2002; 70:11-19.
    • (2002) Am J Hum Genet , vol.70 , pp. 11-19
    • Little, R.D.1    Carulli, J.P.2    Del Mastro, R.G.3
  • 32
    • 0037092049 scopus 로고    scopus 로고
    • Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor
    • Kato M, Patel MS, Levasseur R, et al. Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor. J Cell Biol 2002; 157:303-314.
    • (2002) J Cell Biol , vol.157 , pp. 303-314
    • Kato, M.1    Patel, M.S.2    Levasseur, R.3
  • 33
    • 20244373613 scopus 로고    scopus 로고
    • Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation
    • Glass DA 2nd, Bialek P, Ahn JD, et al. Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Dev Cell 2005; 8:751-764.
    • (2005) Dev Cell , vol.8 , pp. 751-764
    • Glass II, D.A.1    Bialek, P.2    Ahn, J.D.3
  • 34
    • 20444376156 scopus 로고    scopus 로고
    • Essential role of beta-catenin in postnatal bone acquisition
    • Holmen SL, Zylstra CR, Mukherjee A, et al. Essential role of beta-catenin in postnatal bone acquisition. J Biol Chem 2005; 280:21162-21168.
    • (2005) J Biol Chem , vol.280 , pp. 21162-21168
    • Holmen, S.L.1    Zylstra, C.R.2    Mukherjee, A.3
  • 35
    • 56349162283 scopus 로고    scopus 로고
    • Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum
    • Yadav VK, Ryu JH, Suda N, et al. Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum. Cell 2008; 135:825-837.
    • (2008) Cell , vol.135 , pp. 825-837
    • Yadav, V.K.1    Ryu, J.H.2    Suda, N.3
  • 36
    • 34347220867 scopus 로고    scopus 로고
    • Use of antidepressants and rates of hip bone loss in older women: The study of osteoporotic fractures
    • Diem SJ, Blackwell TL, Stone KL, et al. Use of antidepressants and rates of hip bone loss in older women: the study of osteoporotic fractures. Arch Intern Med 2007; 167:1240-1245.
    • (2007) Arch Intern Med , vol.167 , pp. 1240-1245
    • Diem, S.J.1    Blackwell, T.L.2    Stone, K.L.3
  • 37
    • 33846440508 scopus 로고    scopus 로고
    • Effect of selective serotonin reuptake inhibitors on the risk of fracture
    • Richards JB, Papaioannou A, Adachi JD, et al. Effect of selective serotonin reuptake inhibitors on the risk of fracture. Arch Intern Med 2007; 167:188-194.
    • (2007) Arch Intern Med , vol.167 , pp. 188-194
    • Richards, J.B.1    Papaioannou, A.2    Adachi, J.D.3
  • 38
    • 0032474241 scopus 로고    scopus 로고
    • Use of selective serotonin-reuptake inhibitors of tricyclic antidepressants and risk of hip fractures in elderly people
    • Liu B, Anderson G, Mittmann N, et al. Use of selective serotonin-reuptake inhibitors of tricyclic antidepressants and risk of hip fractures in elderly people. Lancet 1998; 351:1303-1307.
    • (1998) Lancet , vol.351 , pp. 1303-1307
    • Liu, B.1    Anderson, G.2    Mittmann, N.3
  • 39
    • 12344313055 scopus 로고    scopus 로고
    • Inhibition of the serotonin (5-hydroxytryptamine) transporter reduces bone accrual during growth
    • Warden SJ, Robling AG, Sanders MS, et al. Inhibition of the serotonin (5-hydroxytryptamine) transporter reduces bone accrual during growth. Endocrinology 2005; 146:685-693.
    • (2005) Endocrinology , vol.146 , pp. 685-693
    • Warden, S.J.1    Robling, A.G.2    Sanders, M.S.3
  • 40
    • 0029935931 scopus 로고    scopus 로고
    • Regulation of insulin secretion and blood glucose metabolism by adrenomedullin
    • Martinez A, Weaver C, Lopez J, et al. Regulation of insulin secretion and blood glucose metabolism by adrenomedullin. Endocrinology 1996; 137:2626-2632.
    • (1996) Endocrinology , vol.137 , pp. 2626-2632
    • Martinez, A.1    Weaver, C.2    Lopez, J.3
  • 41
    • 0028950047 scopus 로고
    • Amylin stimulates osteoblast proliferation and increases mineralized bone volume in adult mice
    • Cornish J, Callon KE, Cooper GJ, Reid IR. Amylin stimulates osteoblast proliferation and increases mineralized bone volume in adult mice. Biochem Biophys Res Commun 1995; 207:133-139.
    • (1995) Biochem Biophys Res Commun , vol.207 , pp. 133-139
    • Cornish, J.1    Callon, K.E.2    Cooper, G.J.3    Reid, I.R.4
  • 42
    • 0034896824 scopus 로고    scopus 로고
    • Effects of calcitonin, amylin, and calcitonin gene-related peptide on osteoclast development
    • Cornish J, Callon KE, Bava U, et al. Effects of calcitonin, amylin, and calcitonin gene-related peptide on osteoclast development. Bone 2001; 29:162-168.
    • (2001) Bone , vol.29 , pp. 162-168
    • Cornish, J.1    Callon, K.E.2    Bava, U.3
  • 43
    • 0031741159 scopus 로고    scopus 로고
    • Systemic administration of amylin increases bone mass, linear growth, and adiposity in adult male mice
    • Cornish J, Callon KE, King AR, et al. Systemic administration of amylin increases bone mass, linear growth, and adiposity in adult male mice. Am J Physiol 1998; 275 (4 Pt 1):E694-E699.
    • (1998) Am J Physiol , vol.275 , Issue.4 PART 1
    • Cornish, J.1    Callon, K.E.2    King, A.R.3
  • 45
    • 0035059219 scopus 로고    scopus 로고
    • Amylin and bone metabolism in streptozotocin-induced diabetic rats
    • Horcajada-Molteni MN, Chanteranne B, Lebecque P, et al. Amylin and bone metabolism in streptozotocin-induced diabetic rats. J Bone Miner Res 2001; 16:958-965.
    • (2001) J Bone Miner Res , vol.16 , pp. 958-965
    • Horcajada-Molteni, M.N.1    Chanteranne, B.2    Lebecque, P.3
  • 46
    • 68849117359 scopus 로고    scopus 로고
    • Effects of amylin on bone development and egg production in hens
    • Guzel S, Gunes N, Yildiz H, Yilmaz B. Effects of amylin on bone development and egg production in hens. Poult Sci 2009; 88:1719-1724.
    • (2009) Poult Sci , vol.88 , pp. 1719-1724
    • Guzel, S.1    Gunes, N.2    Yildiz, H.3    Yilmaz, B.4
  • 47
    • 10744220002 scopus 로고    scopus 로고
    • Amylin inhibits bone resorption while the calcitonin receptor controls bone formation in vivo
    • Dacquin R, Davey RA, Laplace C, et al. Amylin inhibits bone resorption while the calcitonin receptor controls bone formation in vivo. J Cell Biol 2004; 164:509-514.
    • (2004) J Cell Biol , vol.164 , pp. 509-514
    • Dacquin, R.1    Davey, R.A.2    Laplace, C.3
  • 48
    • 33746090881 scopus 로고    scopus 로고
    • Effects of amylin deficiency on trabecular bone in young mice are sex-dependent
    • Davey RA, Moore AJ, Chiu MW, et al. Effects of amylin deficiency on trabecular bone in young mice are sex-dependent. Calcif Tissue Int 2006; 78:398-403.
    • (2006) Calcif Tissue Int , vol.78 , pp. 398-403
    • Davey, R.A.1    Moore, A.J.2    Chiu, M.W.3
  • 49
    • 0344736959 scopus 로고    scopus 로고
    • Diabetes mellitus: Does it affect bone?
    • Schwartz AV. Diabetes mellitus: does it affect bone? Calcif Tissue Int 2003; 73:515-519.
    • (2003) Calcif Tissue Int , vol.73 , pp. 515-519
    • Schwartz, A.V.1
  • 50
    • 12144289840 scopus 로고    scopus 로고
    • Amylin fasting plasma levels are decreased in patients with osteoporosis
    • Bronsky J, Prusa R. Amylin fasting plasma levels are decreased in patients with osteoporosis. Osteoporos Int 2004; 15:243-247.
    • (2004) Osteoporos Int , vol.15 , pp. 243-247
    • Bronsky, J.1    Prusa, R.2
  • 51
    • 0031790302 scopus 로고    scopus 로고
    • Human aging is associated with parallel reductions in insulin and amylin release
    • Dechenes CJ, Verchere CB, Andrikopoulos S, Kahn SE. Human aging is associated with parallel reductions in insulin and amylin release. Am J Physiol 1998; 275 (5 Pt 1):E785-E791.
    • (1998) Am J Physiol , vol.275 , Issue.5 PART 1
    • Dechenes, C.J.1    Verchere, C.B.2    Andrikopoulos, S.3    Kahn, S.E.4
  • 52
    • 0032878303 scopus 로고    scopus 로고
    • The effect of pramlintide (amylin analogue) treatment on bone metabolism and bone density in patients with type 1 diabetes mellitus
    • Borm AK, Klevesath MS, Borcea V, et al. The effect of pramlintide (amylin analogue) treatment on bone metabolism and bone density in patients with type 1 diabetes mellitus. Horm Metab Res 1999; 31:472-475.
    • (1999) Horm Metab Res , vol.31 , pp. 472-475
    • Borm, A.K.1    Klevesath, M.S.2    Borcea, V.3
  • 53
    • 0031417538 scopus 로고    scopus 로고
    • Adrenomedullin is a potent stimulator of osteoblastic activity in vitro and in vivo
    • Cornish J, Callon KE, Coy DH, et al. Adrenomedullin is a potent stimulator of osteoblastic activity in vitro and in vivo. Am J Physiol 1997; 273 (6 Pt 1): E1113-E1120.
    • (1997) Am J Physiol , vol.273 , Issue.6 PART 1
    • Cornish, J.1    Callon, K.E.2    Coy, D.H.3
  • 54
    • 0035895276 scopus 로고    scopus 로고
    • Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional adrenomedullin gene
    • Caron KM, Smithies O. Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional adrenomedullin gene. Proc Natl Acad Sci U S A 2001; 98:615-619.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 615-619
    • Caron, K.M.1    Smithies, O.2
  • 55
    • 0035049965 scopus 로고    scopus 로고
    • A potential role for adrenomedullin as a local regulator of bone growth
    • Naot D, Callon KE, Grey A, et al. A potential role for adrenomedullin as a local regulator of bone growth. Endocrinology 2001; 142:1849-1857.
    • (2001) Endocrinology , vol.142 , pp. 1849-1857
    • Naot, D.1    Callon, K.E.2    Grey, A.3
  • 56
    • 0036948177 scopus 로고    scopus 로고
    • Adrenomedullin stimulates the growth of cultured normal human osteoblasts as an autocrine/paracine regulator
    • Hamada H, Kitamura K, Chosa E, et al. Adrenomedullin stimulates the growth of cultured normal human osteoblasts as an autocrine/paracine regulator. Peptides 2002; 23:2163-2168.
    • (2002) Peptides , vol.23 , pp. 2163-2168
    • Hamada, H.1    Kitamura, K.2    Chosa, E.3
  • 57
    • 1942424868 scopus 로고    scopus 로고
    • Shared pathways of osteoblast mitogenesis induced by amylin, adrenomedullin, and IGF-1
    • Cornish J, Grey A, Callon KE, et al. Shared pathways of osteoblast mitogenesis induced by amylin, adrenomedullin, and IGF-1. Biochem Biophys Res Commun 2004; 318:240-246.
    • (2004) Biochem Biophys Res Commun , vol.318 , pp. 240-246
    • Cornish, J.1    Grey, A.2    Callon, K.E.3
  • 58
    • 39149124871 scopus 로고    scopus 로고
    • Adrenomedullin is antiapoptotic in osteoblasts through CGRP1 receptors and MEK-ERK pathway
    • Uzan B, Villemin A, Garel JM, Cressent M. Adrenomedullin is antiapoptotic in osteoblasts through CGRP1 receptors and MEK-ERK pathway. J Cell Physiol 2008; 215:122-128.
    • (2008) J Cell Physiol , vol.215 , pp. 122-128
    • Uzan, B.1    Villemin, A.2    Garel, J.M.3    Cressent, M.4
  • 59
    • 0035655635 scopus 로고    scopus 로고
    • Preptin derived from proinsulin-like growth factor II (proIGF-II) is secreted from pancreatic islet beta-cells and enhances insulin secretion
    • Buchanan CM, Phillips AR, Cooper GJ. Preptin derived from proinsulin-like growth factor II (proIGF-II) is secreted from pancreatic islet beta-cells and enhances insulin secretion. Biochem J 2001; 360 (Pt 2):431-439.
    • (2001) Biochem J , vol.360 , Issue.PART 2 , pp. 431-439
    • Buchanan, C.M.1    Phillips, A.R.2    Cooper, G.J.3
  • 60
    • 33845975599 scopus 로고    scopus 로고
    • Preptin, another peptide product of the pancreatic beta-cell, is osteogenic in vitro and in vivo
    • Cornish J, Callon KE, Bava U, et al. Preptin, another peptide product of the pancreatic beta-cell, is osteogenic in vitro and in vivo. Am J Physiol 2007; 292:E117-E122.
    • (2007) Am J Physiol , vol.292
    • Cornish, J.1    Callon, K.E.2    Bava, U.3
  • 61
    • 77953609220 scopus 로고    scopus 로고
    • Connective tissue growth factor is a downstream mediator for preptin-induced proliferation and differentiation in human osteoblasts
    • Epub ahead of print
    • Liu YS, Lu Y, Liu W, et al. Connective tissue growth factor is a downstream mediator for preptin-induced proliferation and differentiation in human osteoblasts. Amino Acids 2009. [Epub ahead of print]
    • (2009) Amino Acids
    • Liu, Y.S.1    Lu, Y.2    Liu, W.3
  • 62
    • 0036345441 scopus 로고    scopus 로고
    • Use of site-specific antibodies to characterize the circulating form of big insulin-like growth factor II in patients with hepatitis C-associated osteosclerosis
    • Khosla S, Ballard FJ, Conover CA. Use of site-specific antibodies to characterize the circulating form of big insulin-like growth factor II in patients with hepatitis C-associated osteosclerosis. J Clin Endocrinol Metab 2002; 87:3867-3870.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 3867-3870
    • Khosla, S.1    Ballard, F.J.2    Conover, C.A.3
  • 64
    • 33846866509 scopus 로고    scopus 로고
    • Effects of glucose-dependent insulinotropic peptide on osteoclast function
    • Zhong Q, Itokawa T, Sridhar S, et al. Effects of glucose-dependent insulinotropic peptide on osteoclast function. Am J Physiol 2007; 292:E543-E548.
    • (2007) Am J Physiol , vol.292
    • Zhong, Q.1    Itokawa, T.2    Sridhar, S.3
  • 65
    • 41849094819 scopus 로고    scopus 로고
    • Impact of glucose-dependent insulinotropic peptide on age-induced bone loss
    • Ding KH, Shi XM, Zhong Q, et al. Impact of glucose-dependent insulinotropic peptide on age-induced bone loss. J Bone Miner Res 2008; 23: 536-543.
    • (2008) J Bone Miner Res , vol.23 , pp. 536-543
    • Ding, K.H.1    Shi, X.M.2    Zhong, Q.3
  • 66
    • 0035947038 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic peptide is an integrative hormone with osteotropic effects
    • Bollag RJ, Zhong Q, Ding KH, et al. Glucose-dependent insulinotropic peptide is an integrative hormone with osteotropic effects. Mol Cell Endocrinol 2001; 177:35-41.
    • (2001) Mol Cell Endocrinol , vol.177 , pp. 35-41
    • Bollag, R.J.1    Zhong, Q.2    Ding, K.H.3
  • 67
    • 34147142997 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic peptideoverexpressing transgenic mice have increased bone mass
    • Xie D, Zhong Q, Ding KH, et al. Glucose-dependent insulinotropic peptideoverexpressing transgenic mice have increased bone mass. Bone 2007; 40:1352-1360.
    • (2007) Bone , vol.40 , pp. 1352-1360
    • Xie, D.1    Zhong, Q.2    Ding, K.H.3
  • 68
    • 28844478542 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypeptide receptor knockout mice have altered bone turnover
    • Xie D, Cheng H, Hamrick M, et al. Glucose-dependent insulinotropic polypeptide receptor knockout mice have altered bone turnover. Bone 2005; 37:759-769.
    • (2005) Bone , vol.37 , pp. 759-769
    • Xie, D.1    Cheng, H.2    Hamrick, M.3
  • 69
    • 33745658853 scopus 로고    scopus 로고
    • Gastric inhibitory polypeptide as an endogenous factor promoting new bone formation after food ingestion
    • Tsukiyama K, Yamada Y, Yamada C, et al. Gastric inhibitory polypeptide as an endogenous factor promoting new bone formation after food ingestion. Mol Endocrinol 2006; 20:1644-1651.
    • (2006) Mol Endocrinol , vol.20 , pp. 1644-1651
    • Tsukiyama, K.1    Yamada, Y.2    Yamada, C.3
  • 70
    • 10744224629 scopus 로고    scopus 로고
    • Role of gastrointestinal hormones in postprandial reduction of bone resorption
    • Henriksen DB, Alexandersen P, Bjarnason NH, et al. Role of gastrointestinal hormones in postprandial reduction of bone resorption. J Bone Miner Res 2003; 18:2180-2189.
    • (2003) J Bone Miner Res , vol.18 , pp. 2180-2189
    • Henriksen, D.B.1    Alexandersen, P.2    Bjarnason, N.H.3
  • 71
    • 0942278946 scopus 로고    scopus 로고
    • Reduction of nocturnal rise in bone resorption by subcutaneous GLP-2
    • Henriksen DB, Alexandersen P, Byrjalsen I, et al. Reduction of nocturnal rise in bone resorption by subcutaneous GLP-2. Bone 2004; 34:140-147.
    • (2004) Bone , vol.34 , pp. 140-147
    • Henriksen, D.B.1    Alexandersen, P.2    Byrjalsen, I.3
  • 72
    • 33846840695 scopus 로고    scopus 로고
    • Disassociation of bone resorption and formation by GLP-2: A 14-day study in healthy postmenopausal women
    • Henriksen DB, Alexandersen P, Hartmann B, et al. Disassociation of bone resorption and formation by GLP-2: a 14-day study in healthy postmenopausal women. Bone 2007; 40:723-729.
    • (2007) Bone , vol.40 , pp. 723-729
    • Henriksen, D.B.1    Alexandersen, P.2    Hartmann, B.3
  • 73
    • 70349279885 scopus 로고    scopus 로고
    • Four-month treatment with GLP-2 significantly increases hip BMD: A randomized, placebo-controlled, dose-ranging study in postmenopausal women with low BMD
    • Henriksen DB, Alexandersen P, Hartmann B, et al. Four-month treatment with GLP-2 significantly increases hip BMD: a randomized, placebo-controlled, dose-ranging study in postmenopausal women with low BMD. Bone 2009; 45:833-842.
    • (2009) Bone , vol.45 , pp. 833-842
    • Henriksen, D.B.1    Alexandersen, P.2    Hartmann, B.3
  • 74
    • 34250217756 scopus 로고    scopus 로고
    • Bone resorption is decreased postprandially by intestinal factors and glucagon-like peptide-2 is a possible candidate
    • Holst JJ, Hartmann B, Gottschalck IB, et al. Bone resorption is decreased postprandially by intestinal factors and glucagon-like peptide-2 is a possible candidate. Scand J Gastroenterol 2007; 42:814-820.
    • (2007) Scand J Gastroenterol , vol.42 , pp. 814-820
    • Holst, J.J.1    Hartmann, B.2    Gottschalck, I.B.3
  • 75
    • 54349104953 scopus 로고    scopus 로고
    • Effects of treatment with glucagon-like peptide-2 on bone resorption in colectomized patients with distal ileostomy or jejunostomy and short-bowel syndrome
    • Gottschalck IB, Jeppesen PB, Hartmann B, et al. Effects of treatment with glucagon-like peptide-2 on bone resorption in colectomized patients with distal ileostomy or jejunostomy and short-bowel syndrome. Scand J Gastroenterol 2008; 43:1304-1310.
    • (2008) Scand J Gastroenterol , vol.43 , pp. 1304-1310
    • Gottschalck, I.B.1    Jeppesen, P.B.2    Hartmann, B.3
  • 76
    • 69249219020 scopus 로고    scopus 로고
    • Short bowel patients treated for two years with glucagon-like peptide 2: Effects on intestinal morphology and absorption, renal function, bone and body composition, and muscle function
    • Jeppesen PB, Lund P, Gottschalck IB, et al. Short bowel patients treated for two years with glucagon-like peptide 2: effects on intestinal morphology and absorption, renal function, bone and body composition, and muscle function. Gastroenterol Res Pract 2009; 2009:616054.
    • (2009) Gastroenterol Res Pract , vol.2009 , pp. 616054
    • Jeppesen, P.B.1    Lund, P.2    Gottschalck, I.B.3
  • 77
    • 38549146030 scopus 로고    scopus 로고
    • The murine glucagon-like peptide-1 receptor is essential for control of bone resorption
    • Yamada C, Yamada Y, Tsukiyama K, et al. The murine glucagon-like peptide-1 receptor is essential for control of bone resorption. Endocrinology 2008; 149:574-579.
    • (2008) Endocrinology , vol.149 , pp. 574-579
    • Yamada, C.1    Yamada, Y.2    Tsukiyama, K.3
  • 78
    • 0029833629 scopus 로고    scopus 로고
    • Effects of glucagon and glucagon-like peptide-1-(7-36) amide on C cells from rat thyroid and medullary thyroid carcinoma CA-77 cell line
    • Crespel A, De Boisvilliers F, Gros L, Kervran A. Effects of glucagon and glucagon-like peptide-1-(7-36) amide on C cells from rat thyroid and medullary thyroid carcinoma CA-77 cell line. Endocrinology 1996; 137:3674-3680.
    • (1996) Endocrinology , vol.137 , pp. 3674-3680
    • Crespel, A.1    De Boisvilliers, F.2    Gros, L.3    Kervran, A.4
  • 79
    • 0030590526 scopus 로고    scopus 로고
    • Expression of glucagon-like peptide 1 receptor in a murine C cell line: Regulation of calcitonin gene by glucagonlike peptide 1
    • Lamari Y, Boissard C, Moukhtar MS, et al. Expression of glucagon-like peptide 1 receptor in a murine C cell line: regulation of calcitonin gene by glucagonlike peptide 1. FEBS Lett 1996; 393:248-252.
    • (1996) FEBS Lett , vol.393 , pp. 248-252
    • Lamari, Y.1    Boissard, C.2    Moukhtar, M.S.3
  • 80
    • 67349094596 scopus 로고    scopus 로고
    • Effect of GLP-1 treatment on bone turnover in normal, type 2 diabetic, and insulin-resistant states
    • Nuche-Berenguer B, Moreno P, Esbrit P, et al. Effect of GLP-1 treatment on bone turnover in normal, type 2 diabetic, and insulin-resistant states. Calcif Tissue Int 2009; 84:453-461.
    • (2009) Calcif Tissue Int , vol.84 , pp. 453-461
    • Nuche-Berenguer, B.1    Moreno, P.2    Esbrit, P.3
  • 81
    • 75149191059 scopus 로고    scopus 로고
    • Exendin-4 exerts osteogenic actions in insulin-resistant and type 2 diabetic states
    • Epub ahead of print
    • Nuche-Berenguer B, Moreno P, Portal-Nunez S, et al. Exendin-4 exerts osteogenic actions in insulin-resistant and type 2 diabetic states. Regul Pept 2009. [Epub ahead of print]
    • (2009) Regul Pept
    • Nuche-Berenguer, B.1    Moreno, P.2    Portal-Nunez, S.3
  • 82
    • 0028845124 scopus 로고
    • Cholecystokinin receptors
    • Wank SA. Cholecystokinin receptors. Am J Physiol 1995; 269 (5 Pt 1): G628-G646.
    • (1995) Am J Physiol , vol.269 , Issue.5 PART 1
    • Wank, S.A.1
  • 83
    • 34247877772 scopus 로고    scopus 로고
    • Cholecystokinin down-regulation by RNA interference impairs Ewing tumor growth
    • Carrillo J, Garcia-Aragoncillo E, Azorin D, et al. Cholecystokinin down-regulation by RNA interference impairs Ewing tumor growth. Clin Cancer Res 2007; 13:2429-2440.
    • (2007) Clin Cancer Res , vol.13 , pp. 2429-2440
    • Carrillo, J.1    Garcia-Aragoncillo, E.2    Azorin, D.3
  • 84
    • 70149099106 scopus 로고    scopus 로고
    • Devazepide, a nonpeptide antagonist of CCK receptors, induces apoptosis and inhibits Ewing tumor growth
    • Carrillo J, Agra N, Fernandez N, et al. Devazepide, a nonpeptide antagonist of CCK receptors, induces apoptosis and inhibits Ewing tumor growth. Anticancer Drugs 2009; 20:527-533.
    • (2009) Anticancer Drugs , vol.20 , pp. 527-533
    • Carrillo, J.1    Agra, N.2    Fernandez, N.3


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