Adrenomedullin stimulates the growth of cultured normal human osteoblasts as an autocrine/paracine regulator

Peptides

Volumn 23, Issue 12, 2002, Pages 2163-2168

  Hamada, H ^a   Kitamura, K ^a   Chosa, E ^a   Eto, T ^a   Tajima, N ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

Author keywords

Adrenomedullin; cAMP; Osteoblast; Proliferation

Indexed keywords

ADRENOMEDULLIN; CYCLIC AMP; MONOCLONAL ANTIBODY; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE;

ARTICLE; AUTOCRINE EFFECT; CELL GROWTH; CELL PROLIFERATION; ENZYME SYNTHESIS; GROWTH STIMULATION; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; OSTEOBLAST; PARACRINE SIGNALING; PRIORITY JOURNAL;

ADRENOMEDULLIN; ANTIBODIES, MONOCLONAL; AUTOCRINE COMMUNICATION; CELL DIVISION; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; OSTEOBLASTS; PARACRINE COMMUNICATION; PEPTIDES; RADIOIMMUNOASSAY; TIME FACTORS;

EID: 0036948177     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(02)00259-0     Document Type: Article

References (24)

1. Bernard G.W., Shih C. The osteogenic stimulating effect of neuroactive calcitonin gene-related peptide. Peptides. 11:1990;625-632.
2. Cornish J., Callon K.E., Coy D.H., Jiang N.Y., Xiao L., Cooper G.J.et al. Adrenomedullin is a potent stimulator of osteoblastic activity in vitro and in vivo. Am. J. Physiol. 273(6 Pt 1):1997;E1113-E1120.
3. Cornish J., Callon K.E., Lin C.Q.X., Xiao C.L., Gamble G.D., Cooper G.J.S.et al. Comparison of effect of calcitonin gene related peptide and amylin on osteoblasts. J. Bone Miner. Res. 14:1999;1302-1309.
4. Cornish J., Callon K.E., Bava U., Coy D.H., Mulvey T.B., Murrey M.A.et al. Systemic administration of adrenomedullin (27-52) increases bone volume and strength in male mice. Endocrinology. 170(1):2001;251-257.
5. Dorit N., Karen E.C., Andrew G., Garth J.S.C., Ian R.R., Jullian C. A potential role for adrenomedullin as a local regulator of bone growth. Endocrinology. 142:2001;1849-1857.
6. Galfre G., Milstein C. Preparation of monoclonal antibodies: strategies and procedures. Methods Enzymol. 73:1981;3-46.
7. Hirata Y., Hayakawa H., Suzuki Y., Suzuki E., Ikenouchi H., Kohmoto O.et al. Mechanisms of adrenomedullin-induced vasodilation in the rat kidney. Hypertension. 25(Part 2):1995;790-795.
8. Isabella V., Raffaella M., Francesca P., Flavio R., Alessandro R., Francesca G. Effects of calcitonin gene-related peptide and amylin on human osteoblast-like cells proliferation. Euro. J. Pharm. 409:2000;273-278.
9. Kitamura K., Kangawa K., Kawamoto M., Ichiki Y., Nakamura S., Mastuo H.et al. Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma. Biochem. Biophys. Res. Commun. 192:1993;553-560.
10. Kitamura K., Ichiki Y., Tanaka M., Kawamoto M., Emura J., Sakakibara S.et al. Immunoreactive adrenomedullin in human plasma. FEBS Lett. 341:1994;288-290.
11. Kloth S., Ebenbeck C., Kubitza M., Schmidbauer A., Rockl W., Minnuth W.W. Stimulation of renal microvascular development under organotypic culture conditions. FASEB. 9:1995;963-967.
12. Michelangeli V.P., Findlay D.M., Fletcher A., Martin T.J. Calcitonin gene-related peptide (CGRP) acts independently of calcitonin on cAMP formation in clonal osteogenic sarcoma cells (UMR 106-01). Calcif. Tissue. Int. 39:1986;44-48.
13. Michelangeli V.P., Fletcher A.E., Allan E.H., Nicholson G.C., Martin T.J. Effects of calcitonin gene-related peptide on cAMP formation in chicken, rat, and mouse bone cells. J. Bone Miner. Res. 4:1989;269-272.
14. Miller M.J., Martinez A., Unsworth E.J., Thiele C.J., Moody T.W., Elsasser T.et al. Adrenomedullin expression in human tumor cell lines. It's potential role as an autocrine growth factor. J. Biol. Chem. 271(38):1996;23345-23351.
15. Moody T.W., Miller M.J., Martinez A., Unsworth E., Cuttitta F. Adrenomedullin binds with high affinity, elevates cyclic AMP, and stimulates c-fos mRNA in C6 glioma cells. Peptides. 18(8):1997;1111-1115.
16. Oath H., Tsuji T., Asai S., Sasakura K., Teraoka H., Kitamura K.et al. One-step direct assay for mature-type adrenomedullin with monoclonal antibodies. Clin. Chem. 45(2):1999;244-251.
17. Reid IR, Cornish J. Amylin and CGRP. In: Bilezekian JP, Raisz LG, Rodan GA, editors. Principles of bone biology, 1st ed. San Diego, CA: Academic Press; 1996. p. 495-505.
18. Sakata J., Shimokubo T., Kitamura K. Distribution and characterization of immunoreactive rat adrenomedullin in tissue and plasma. FEBS Lett. 352:1994;105-108.
19. Shih C., Bernard G.W. Calcitonin gene-related peptide enhances bone colony development in vitro. Clin. Orthop. 334:1997;335-344.
20. Siddhanti S.R., Quales L.D. Molecular to pharmacological control of osteoblast proliferation and differentiation. J. Cell. Biochem. 55:1994;310-320.
21. 2+ mobilization, in bovine aortic endothelial cells. J. Biol. Chem. 270:1995;4412-4417.
22. Sugo S., Minamino N., Kangawa K., Miyamoto K., Kitamura K., Sakata J.et al. Endothelial cells actively synthesize and secrete adrenomedullin. Biochem. Biophys. Res. Commun. 201:1994;1160-1166.
23. Villa I., Rubinacci A., Ravasi F., Ferrara F., Guidobono F. Effects of amylin on human osteoblast-like cells. Peptides. 18:1997;537-540.
24. Yuko I., Yushiro I., Miho T., Kazuo K., Kenji K., Naoto M.et al. Adrenomedullin stimulates cyclic AMP formation in rat vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 200:1994;642-646.