8-pCPT-cGMP stimulates αβγ-ENaC activity in oocytes as an external ligand requiring specific nucleotide moieties

American Journal of Physiology - Renal Physiology

Volumn 298, Issue 2, 2010, Pages

  Nie, Hong Guang ^a   Zhang, Wei ^b   Han, Dong Yun ^a   Li, Qing Nan ^c   Li, Jun ^b   Zhao, Run Zhen ^a   Su, Xue Feng ^a   Peng, Ji Bin ^b   Ji, Hong Long ^a  

^a UNIVERSITY OF TEXAS AT TYLER   (United States)

^b and Clinical Center   (United States)

^c GUANGDONG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Amiloride; Domain mapping; Guanosine 3 ,5 cyclic monophosphate

Indexed keywords

8 (4 CHLOROPHENYLTHIO) CYCLIC GMP; AMILORIDE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; EPITHELIAL SODIUM CHANNEL; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PROTEIN KINASE C; SMALL INTERFERING RNA;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SITE DIRECTED MUTAGENESIS; XENOPUS;

EID: 75149140947     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00307.2009     Document Type: Article

References (56)

1. Ahn YJ, Brooker DR, Kosari F, Harte BJ, Li J, Mackler SA, Kleyman TR. Cloning and functional expression of the mouse epithelial sodium channel. Am J Physiol Renal Physiol 277: F121-F129, 1999.
2. + channel. J Gen Physiol 108: 49-65, 1996.
3. + channel by the protein kinase CK2. J Biol Chem 283: 13225-13232, 2008.
4. Beckman JS, Koppenol WH. Nitric oxide, superoxide, peroxynitrite: the good, the bad, and ugly. Am J Physiol Cell Physiol 271: C1424-C1437, 1996.
5. + transport. Am J Physiol Lung Cell Mol Physiol 288: L813-L819, 2005.
6. + channel is made of three homologous subunits. Nature 367: 463-467, 1994.
7. Chraibi A, Schnizler M, Clauss W, Horisberger JD. Effects of 8-cpt-cAMP on the epithelial sodium channel expressed in Xenopus oocytes. J Membr Biol 183: 15-23, 2001.
8. Cowley S, Ko M, Pick N, Chow R, Downing KJ, Gordhan BG, Betts JC, Mizrahi V, Smith DA, Stokes RW, Av-Gay Y. The Mycobacterium tuberculosis protein serine/threonine kinase PknG is linked to cellular glutamate/glutamine levels and is important for growth in vivo. Mol Microbiol 52: 1691-1702, 2004.
9. Davis IC, Xu A, Gao Z, Hickman-Davis JM, Factor P, Sullender WM, Matalon S. Respiratory syncytial virus induces insensitivity to beta-adrenergic agonists in mouse lung epithelium in vivo. Am J Physiol Lung Cell Mol Physiol 293: L281-L289, 2007.
10. + channels. Proc Natl Acad Sci USA 101: 11886-11890, 2004.
11. Firsov D, Schild L, Gautschi I, Merillat AM, Schneeberger E, Rossier BC. Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: a quantitative approach. Proc Natl Acad Sci USA 93: 15370-15375, 1996.
12. Gamm DM, Francis SH, Angelotti TP, Corbin JD, Uhler MD. The type II isoform of cGMP-dependent protein kinase is dimeric and possesses regulatory and catalytic properties distinct from the type I isoforms. J Biol Chem 270: 27380-27388, 1995.
13. + channel. Physiol Rev 68: 309-373, 1988.
14. Golin-Bisello F, Bradbury N, Ameen N. STa and cGMP stimulate CFTR translocation to the surface of villus enterocytes in rat jejunum and is regulated by protein kinase G. Am J Physiol Cell Physiol 289: C708-C716, 2005.
15. Gow AJ, Farkouh CR, Munson DA, Posencheg MA, Ischiropoulos H. Biological significance of nitric oxide-mediated protein modifications. Am J Physiol Lung Cell Mol Physiol 287: L262-L268, 2004.
16. Hansson JH, Nelson-Williams C, Suzuki H, Schild L, Shimkets R, Lu Y, Canessa C, Iwasaki T, Rossier B, Lifton RP. Hypertension caused by a truncated epithelial sodium channel gamma subunit: genetic heterogeneity of Liddle syndrome. Nat Genet 11: 76-82, 1995.
17. Hofmann F, Feil R, Kleppisch T, Schlossmann J. Function of cGMP-dependent protein kinases as revealed by gene deletion. Physiol Rev 86: 1-23, 2006.
18. Horisberger JD, Chraibi A. Epithelial sodium channel: a ligand-gated channel? Nephron Physiol 96: p37-p41, 2004.
19. + channels expressed in Xenopus oocytes. J Biol Chem 274: 37693-37704, 1999.
20. Ji HL, Parker S, Langloh AL, Fuller CM, Benos DJ. Point mutations in the post-M2 region of human α-ENaC regulate cation selectivity. Am J Physiol Cell Physiol 281: C64-C74, 2001.
21. Ji HL, Song W, Gao Z, Su XF, Nie HG, Jiang Y, Peng JB, He YX, Liao Y, Zhou YJ, Tousson A, Matalon S. SARS-CoV proteins decrease levels and activity of human ENaC via activation of distinct PKC isoforms. Am J Physiol Lung Cell Mol Physiol 296: L372-L383, 2009.
22. Ji HL, Su XF, Kedar S, Li J, Barbry P, Smith PR, Matalon S, Benos DJ. Delta-subunit confers novel biophysical features to alpha beta gamma-human epithelial sodium channel (ENaC) via a physical interaction. J Biol Chem 281: 8233-8241, 2006.
23. Kaur T, Ganguly NK. Modulation of gut physiology through enteric toxins. Mol Cell Biochem 253: 15-19, 2003.
24. + channel. J Gen Physiol 114: 13-30, 1999.
25. Kellenberger S, Schild L. Epithelial sodium channel/degenerin family of ion channels: a variety of functions for a shared structure. Physiol Rev 82: 735-767, 2002.
26. + channel. A new channel type with homologies to Caenorhabditis elegans degenerins. FEBS Lett 318: 95-99, 1993.
27. Lohmann SM, Walter U. Tracking functions of cGMP-dependent protein kinases (cGK). Front Biosci 10: 1313-1328, 2005.
28. Lu M, Echeverri F, Kalabat D, Laita B, Dahan DS, Smith RD, Xu H, Staszewski L, Yamamoto J, Ling J, Hwang N, Kimmich R, Li P, Patron E, Keung W, Patron A, Moyer BD. Small molecule activator of the human epithelial sodium channel. J Biol Chem 283: 11981-11994, 2008.
29. Mann EA, Jump ML, Wu J, Yee E, Giannella RA. Mice lacking the guanylyl cyclase C receptor are resistant to STa-induced intestinal secretion. Biochem Biophys Res Commun 239: 463-466, 1997.
30. Matalon S, Hardiman KM, Jain L, Eaton DC, Kotlikoff M, Eu JP, Sun J, Meissner G, Stamler JS. Regulation of ion channel structure and function by reactive oxygen-nitrogen species. Am J Physiol Lung Cell Mol Physiol 285: L1184-L1189, 2003.
31. + channel. Am J Physiol Lung Cell Mol Physiol 266: L728-L734, 1994.
32. McEneaney V, Harvey BJ, Thomas W. Aldosterone regulates rapid trafficking of epithelial sodium channel subunits in renal cortical collecting duct cells via protein kinase D activation. Mol Endocrinol 22: 881-892, 2008.
33. Nie HG, Chen L, Han DY, Li J, Song WF, Wei SP, Fang XH, Gu X, Matalon S, Ji HL. Regulation of epithelial sodium channels by cGMP/PKGII. J Physiol 587: 2663-2676, 2009.
34. + channels by nucleotides in pleural mesothelial cells. Am J Respir Cell Mol Biol 40: 543-554, 2009.
35. Renauld S, Allache R, Chraibi C. Ile481 from the guinea pig alpha-subunit plays a major role in the activation of ENaC by cpt-cAMP. Cell Physiol Biochem 22: 101-108, 2008.
36. Scherr N, Honnappa S, Kunz G, Mueller P, Jayachandran R, Winkler F, Pieters J, Steinmetz MO. Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. Proc Natl Acad Sci USA 104: 12151-12156, 2007.
37. Schild L, Canessa CM, Shimkets RA, Gautschi I, Lifton RP, Rossier BC. A mutation in the epithelial sodium channel causing Liddle disease increases channel activity in the Xenopus laevis oocyte expression system. Proc Natl Acad Sci USA 92: 5699-5703, 1995.
38. Schlossmann J, Feil R, Hofmann F. Insights into cGMP signalling derived from cGMP kinase knockout mice. Front Biosci 10: 1279-1289, 2005.
39. Schlossmann J, Feil R, Hofmann F. Signaling through NO and cGMP-dependent protein kinases. Ann Med 35: 21-27, 2003.
40. Schlossmann J, Hofmann F. cGMP-dependent protein kinases in drug discovery. Drug Discov Today 10: 627-634, 2005.
41. Sheng S, McNulty KA, Harvey JM, Kleyman TR. Second transmembrane domains of ENaC subunits contribute to ion permeation and selectivity. J Biol Chem 276: 44091-44098, 2001.
42. Shi H, Asher C, Chigaev A, Yung Y, Reuveny E, Seger R, Garty H. Interactions of beta and gamma ENaC with Nedd4 can be facilitated by an ERK-mediated phosphorylation. J Biol Chem 277: 13539-13547, 2002.
43. Shi H, Asher C, Yung Y, Kligman L, Reuveny E, Seger R, Garty H. Casein kinase 2 specifically binds to and phosphorylates the carboxy termini of ENaC subunits. Eur J Biochem 269: 4551-4558, 2002.
44. Shimkets RA, Lifton R, Canessa CM. In vivo phosphorylation of the epithelial sodium channel. Proc Natl Acad Sci USA 95: 3301-3305, 1998.
45. Song W, Matalon S. Modulation of alveolar fluid clearance by reactive oxygen-nitrogen intermediates. Am J Physiol Lung Cell Mol Physiol 293: L855-L858, 2007.
46. + channel subunit proteins. J Biol Chem 275: 25760-25765, 2000.
47. Sullivan SK, Agellon LB, Schick R. Identification and partial characterization of a domain in CFTR that may bind cyclic nucleotides directly. Curr Biol 5: 1159-1167, 1995.
48. Thippeswamy T, McKay JS, Quinn JP, Morris R. Nitric oxide, a biological double-faced janus-is this good or bad? Histol Histopathol 21: 445-458, 2006.
49. Volk KA, Husted RF, Snyder PM, Stokes JB. Kinase regulation of hENaC mediated through a region in the COOH-terminal portion of the α-subunit. Am J Physiol Cell Physiol 278: C1047-C1054, 2000.
50. Wang W, Li C, Nejsum LN, Li H, Kim SW, Kwon TH, Jonassen TE, Knepper MA, Thomsen K, Frokiaer J, Nielsen S. Biphasic effects of ANP infusion in conscious, euvolumic rats: roles of AQP2 and ENaC trafficking. Am J Physiol Renal Physiol 290: F530-F541, 2006.
51. Ware LB, Matthay MA. Clinical practice. Acute pulmonary edema. N Engl J Med 353: 2788-2796, 2005.
52. + channels in urinary bladder cells of Japanese tree frog, Hyla japonica. J Comp Physiol [B] 177: 503-508, 2007.
53. + channel activity in urinary bladder cells of Japanese tree frog, Hyla japonica. Gen Comp Endocrinol 152: 286-288, 2007.
54. + transport and epithelial sodium channel expression by protein kinase C in rat alveolar epithelial cells. Can J Physiol Pharmacol 83: 977-987, 2005.
55. Yang LM, Rinke R, Korbmacher C. Stimulation of the epithelial sodium channel (ENaC) by cAMP involves putative ERK phosphorylation sites in the C termini of the channel's beta- and gamma-subunit. J Biol Chem 281: 9859-9868, 2006.
56. Zhang W, Mannan I, Schulz S, Parkinson SJ, Alekseev AE, Gomez LA, Terzic A, Waldman SA. Interruption of transmembrane signaling as a novel antisecretory strategy to treat enterotoxigenic diarrhea. FASEB J 13: 913-922, 1999.