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Volumn 72, Issue 19, 2009, Pages 1191-1200

Assessing the metabolic and toxic effects of anticonvulsant doses of polyunsaturated fatty acids on the liver in rats

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; BIOCHEMICAL MARKER; CATALASE; GLUTATHIONE TRANSFERASE A1; GLUTATHIONE TRANSFERASE A4; HYDROXYMETHYLGLUTARYL COENZYME A LYASE; LINOLEIC ACID; LINOLENIC ACID; MESSENGER RNA; MINERAL OIL; PHOSPHOLIPID; POLYUNSATURATED FATTY ACID; SR 3; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 75149133654     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287390903091889     Document Type: Article
Times cited : (4)

References (47)
  • 1
    • 27744514308 scopus 로고    scopus 로고
    • Effect of pentylenetetrazolinduced epileptic seizure on the antioxidant enzyme activities, glutathione and lipid peroxidation levels in rat erythrocytes and liver tissues
    • Akbas, S. H., Yegin, A., and Ozben, T. 2005. Effect of pentylenetetrazolinduced epileptic seizure on the antioxidant enzyme activities, glutathione and lipid peroxidation levels in rat erythrocytes and liver tissues. Clin. Biochem. 38: 1009-1014.
    • (2005) Clin. Biochem. , vol.38 , pp. 1009-1014
    • Akbas, S.H.1    Yegin, A.2    Ozben, T.3
  • 2
    • 0031389685 scopus 로고    scopus 로고
    • Phospholipid fatty acid composition affects enzymatic antioxidant defenses in cultured Swiss 3T3 fibroblasts
    • Benito, S., Fernandez, Y., Mitjavila, S., Moussa, M., Anglade, F., and Periquet, A. 1997. Phospholipid fatty acid composition affects enzymatic antioxidant defenses in cultured Swiss 3T3 fibroblasts. Redox Rep. 3:281-286.
    • (1997) Redox Rep. , vol.3 , pp. 281-286
    • Benito, S.1    Fernandez, Y.2    Mitjavila, S.3    Moussa, M.4    Anglade, F.5    Periquet, A.6
  • 4
    • 45549090724 scopus 로고    scopus 로고
    • Formation of highly reactive cyclopentenone isoprostane compounds (A3/J3-isoprostanes) in vivo from eicosapentaenoic acid
    • Brooks, J. D., Milne, G. L., Yin, H., Sanchez, S. C., Porter, N. A., and Morrow, J. D. 2008. Formation of highly reactive cyclopentenone isoprostane compounds (A3/J3-isoprostanes) in vivo from eicosapentaenoic acid. J. Biol. Chem 283:12043-12055.
    • (2008) J. Biol. Chem , vol.283 , pp. 12043-12055
    • Brooks, J.D.1    Milne, G.L.2    Yin, H.3    Sanchez, S.C.4    Porter, N.A.5    Morrow, J.D.6
  • 5
    • 0032518858 scopus 로고    scopus 로고
    • Molecular cloning of rat mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase and detection of the corresponding mRNA and of those encoding the remaining enzymes comprising the ketogenic 3-hydroxy-3-methylglutaryl-CoA cycle in central nervous system of suckling rat
    • Cullingford, T. E., Dolphin, C. T., Bhakoo, K. K., Peuchen, S., Canevari, L., and Clark., J. B. 1998. Molecular cloning of rat mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase and detection of the corresponding mRNA and of those encoding the remaining enzymes comprising the ketogenic 3-hydroxy-3-methylglutaryl-CoA cycle in central nervous system of suckling rat. Biochem. J. 329:373-381.
    • (1998) Biochem. J. , vol.329 , pp. 373-381
    • Cullingford, T.E.1    Dolphin, C.T.2    Bhakoo, K.K.3    Peuchen, S.4    Canevari, L.5    Clark, J.B.6
  • 6
    • 1042265010 scopus 로고    scopus 로고
    • Metabolic and health implications of moderate ketosis and the ketogenic diet
    • Cunnane, S. C. 2004. Metabolic and health implications of moderate ketosis and the ketogenic diet. Prostaglandins Leukotrienes Essential Fatty Acids 70:233-234.
    • (2004) Prostaglandins Leukotrienes Essential Fatty Acids , vol.70 , pp. 233-234
    • Cunnane, S.C.1
  • 8
    • 54049138751 scopus 로고    scopus 로고
    • N-3 Fatty acids (fish oil) for epilepsy, cardiac risk factors, and risk of SUDEP: Clues from a pilot, double-blind, exploratory study
    • Degiorgio, C. M., Miller, P., Meymandi, S., and Gornbein, J. A. 2008. n-3 Fatty acids (fish oil) for epilepsy, cardiac risk factors, and risk of SUDEP: Clues from a pilot, double-blind, exploratory study. Epilepsy Behav. 13:681-684.
    • (2008) Epilepsy Behav. , vol.13 , pp. 681-684
    • Degiorgio, C.M.1    Miller, P.2    Meymandi, S.3    Gornbein, J.A.4
  • 9
    • 0027078768 scopus 로고
    • Eicosapentaenoic acid at hypotriglyceridemic dose enhances the hepatic antioxidant defense in mice
    • Demoz, A., Willumsen, N., and Berge, R. K. 1992. Eicosapentaenoic acid at hypotriglyceridemic dose enhances the hepatic antioxidant defense in mice. Lipids 27:968-971.
    • (1992) Lipids , vol.27 , pp. 968-971
    • Demoz, A.1    Willumsen, N.2    Berge, R.K.3
  • 10
    • 39049191458 scopus 로고    scopus 로고
    • Effects of different dietary fatty acid supplements upon lipoprotein metabolism and lipid peroxides production in hyperlipidemic rats
    • Dimitrova-Sumkovska, J., Dosic-Markovska, B., Zafirova-Roganovic, D., and Anastasovska, V. 2006. Effects of different dietary fatty acid supplements upon lipoprotein metabolism and lipid peroxides production in hyperlipidemic rats. Prilozi 27:67-86.
    • (2006) Prilozi , vol.27 , pp. 67-86
    • Dimitrova-Sumkovska, J.1    Dosic-Markovska, B.2    Zafirova-Roganovic, D.3    Anastasovska, V.4
  • 11
    • 33748425456 scopus 로고    scopus 로고
    • Systematic study on ROS production induced by oleic, linoleic, and gamma-linolenic acids in human and rat neutrophils
    • Hatanaka, E., Levada-Pires, A. C., Pithon-Curi, T. C., and Curi., R. 2006. Systematic study on ROS production induced by oleic, linoleic, and gamma-linolenic acids in human and rat neutrophils. Free Radical Biol. Med. 41:1124-1132.
    • (2006) Free Radical Biol. Med. , vol.41 , pp. 1124-1132
    • Hatanaka, E.1    Levada-Pires, A.C.2    Pithon-Curi, T.C.3    Curi, R.4
  • 13
    • 33745148616 scopus 로고    scopus 로고
    • Very-long-chain and branched-chain fatty acyl-CoAs are high affinity ligands for the peroxisome proliferator-activated receptor alpha (PPARalpha)
    • Hostetler, H. A., Kier, A. B., and Schroeder, F. 2006. Very-long-chain and branched-chain fatty acyl-CoAs are high affinity ligands for the peroxisome proliferator-activated receptor alpha (PPARalpha). Biochemistry 45:7669-7681.
    • (2006) Biochemistry , vol.45 , pp. 7669-7681
    • Hostetler, H.A.1    Kier, A.B.2    Schroeder, F.3
  • 14
    • 21444456038 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha interacts with high affinity and is conformationally responsive to endogenous ligands
    • Hostetler, H. A., Petrescu, A. D., Kier, A. B., and Schroeder, F. 2005. Peroxisome proliferator-activated receptor alpha interacts with high affinity and is conformationally responsive to endogenous ligands. J. Biol. Chem. 280:18667-18682.
    • (2005) J. Biol. Chem. , vol.280 , pp. 18667-18682
    • Hostetler, H.A.1    Petrescu, A.D.2    Kier, A.B.3    Schroeder, F.4
  • 15
    • 33747148931 scopus 로고    scopus 로고
    • Low liver conversion rate of alpha-linolenic to docosahexaenoic acid in awake rats on a high-docosahexaenoate-containing diet
    • Igarashi, M., Ma, K., Chang, L., Bell, J. M., Rapoport, S. I., and DeMar, J. C., Jr. 2006. Low liver conversion rate of alpha-linolenic to docosahexaenoic acid in awake rats on a high-docosahexaenoate-containing diet. J. Lipid Res. 47:1812-18122.
    • (2006) J. Lipid Res. , vol.47 , pp. 1812-18122
    • Igarashi, M.1    Ma, K.2    Chang, L.3    Bell, J.M.4    Rapoport, S.I.5    DeMar Jr., J.C.6
  • 16
    • 27644577579 scopus 로고    scopus 로고
    • The effects of polyunsaturated: Saturated fatty acids ratios and peroxidisability index values of dietary fats on serum lipid profiles and hepatic enzyme activities in rats
    • Kang, M. J., Shin, M. S., Park, J. N., and Lee, S. S. 2005. The effects of polyunsaturated: saturated fatty acids ratios and peroxidisability index values of dietary fats on serum lipid profiles and hepatic enzyme activities in rats. Br. J. Nutr. 94:526-532.
    • (2005) Br. J. Nutr. , vol.94 , pp. 526-532
    • Kang, M.J.1    Shin, M.S.2    Park, J.N.3    Lee, S.S.4
  • 18
    • 0036690354 scopus 로고    scopus 로고
    • Ketogenic diet: Does acetone stop seizures?
    • Likhodii, S. S., and Burnham, W. M. 2002. Ketogenic diet: Does acetone stop seizures? Med. Sci. Monit. 8:19-24.
    • (2002) Med. Sci. Monit. , vol.8 , pp. 19-24
    • Likhodii, S.S.1    Burnham, W.M.2
  • 20
    • 0033524415 scopus 로고    scopus 로고
    • Ligand selectivity of the peroxisome proliferator-activated receptor alpha
    • Lin, Q., Ruuska, S. E., Shaw, N. S., Dong, D., and Noy, N. 1999. Ligand selectivity of the peroxisome proliferator-activated receptor alpha. Biochemistry 38:185-190.
    • (1999) Biochemistry , vol.38 , pp. 185-190
    • Lin, Q.1    Ruuska, S.E.2    Shaw, N.S.3    Dong, D.4    Noy, N.5
  • 21
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak, K. J., and Schmittgen, T. D. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 22
    • 33846818874 scopus 로고    scopus 로고
    • 4-Hydroxynonenal, a product of oxidative stress, leads to an antioxidant response in optic nerve head astrocytes
    • Malone, P. E., and Hernandez, M. R. 2007. 4-Hydroxynonenal, a product of oxidative stress, leads to an antioxidant response in optic nerve head astrocytes. Exp. Eye Res. 84:444-454.
    • (2007) Exp. Eye Res. , vol.84 , pp. 444-454
    • Malone, P.E.1    Hernandez, M.R.2
  • 24
    • 18344418461 scopus 로고    scopus 로고
    • Aging-related decrease in liver peroxisomal fatty acid oxidation in control and clofibrate-treated mice. A biochemical study and mechanistic approach
    • Perichon, R., and Bourre, J. M. 1996. Aging-related decrease in liver peroxisomal fatty acid oxidation in control and clofibrate-treated mice. A biochemical study and mechanistic approach. Mech. Ageing Dev. 87:115-126.
    • (1996) Mech. Ageing Dev. , vol.87 , pp. 115-126
    • Perichon, R.1    Bourre, J.M.2
  • 25
    • 27844486110 scopus 로고    scopus 로고
    • Modulation of xenobiotic metabolising enzymes by anticarcinogens-Focus on glutathione S-transferases and their role as targets of dietary chemoprevention in colorectal carcinogenesis
    • Pool-Zobel, B., Veeriah, S., and Bohmer, F. D. 2005. Modulation of xenobiotic metabolising enzymes by anticarcinogens-Focus on glutathione S-transferases and their role as targets of dietary chemoprevention in colorectal carcinogenesis. Mutat. Res. 591:74-92.
    • (2005) Mutat. Res. , vol.591 , pp. 74-92
    • Pool-Zobel, B.1    Veeriah, S.2    Bohmer, F.D.3
  • 26
    • 58149250333 scopus 로고    scopus 로고
    • Anticonvulsant effects of linolenic acid are unrelated to brain phospholipid cell membrane compositions
    • Porta, N., Bourgois, B., Galabert, C., Lecointe, C., Cappy, P., Bordet, R., Vallee, L., and Auvin, S. 2009. Anticonvulsant effects of linolenic acid are unrelated to brain phospholipid cell membrane compositions. Epilepsia 50:65-71.
    • (2009) Epilepsia , vol.50 , pp. 65-71
    • Porta, N.1    Bourgois, B.2    Galabert, C.3    Lecointe, C.4    Cappy, P.5    Bordet, R.6    Vallee, L.7    Auvin, S.8
  • 27
    • 0242269459 scopus 로고    scopus 로고
    • Anticonvulsant efficiency, behavioral performance and cortisol levels: A comparison of carbamazepine (CBZ) and a fatty acid compound (SR-3)
    • Rabinovitz, S., Mostofsky, D. I., and Yehuda, S. 2004. Anticonvulsant efficiency, behavioral performance and cortisol levels: A comparison of carbamazepine (CBZ) and a fatty acid compound (SR-3). Psychoneuroendocrinology 29:113-124.
    • (2004) Psychoneuroendocrinology , vol.29 , pp. 113-124
    • Rabinovitz, S.1    Mostofsky, D.I.2    Yehuda, S.3
  • 28
    • 33749057888 scopus 로고    scopus 로고
    • 4-Hydroxynonenal induces mitochondrial oxidative stress, apoptosis and expression of glutathione S-transferase A4-4 and cytochrome P450 2E1 in PC12 cells
    • Raza, H., and John, A. 2006. 4-Hydroxynonenal induces mitochondrial oxidative stress, apoptosis and expression of glutathione S-transferase A4-4 and cytochrome P450 2E1 in PC12 cells. Toxicol. Appl. Pharmacol. 216:309-318.
    • (2006) Toxicol. Appl. Pharmacol. , vol.216 , pp. 309-318
    • Raza, H.1    John, A.2
  • 29
    • 33745288187 scopus 로고    scopus 로고
    • Chemical inducers of rodent glutathione s-transferases down-regulate human GSTA1 transcription through a mechanism involving variant hepatic nuclear factor 1-C
    • Romero, L., Ng, L., and Kirby, G. M. 2006. Chemical inducers of rodent glutathione s-transferases down-regulate human GSTA1 transcription through a mechanism involving variant hepatic nuclear factor 1-C. Mol Pharmacol 70:277-286.
    • (2006) Mol Pharmacol , vol.70 , pp. 277-286
    • Romero, L.1    Ng, L.2    Kirby, G.M.3
  • 30
    • 0141919769 scopus 로고    scopus 로고
    • Long chain polyunsaturate supplementation does not induce excess lipid peroxidation of piglet tissues
    • Sarkadi-Nagy, E., Huang, M. C., Diau, G. Y., Kirwan, R., Chueh Chao, A., Tschanz, C., and Brenna, J. T. 2003. Long chain polyunsaturate supplementation does not induce excess lipid peroxidation of piglet tissues. Eur. J. Nutr. 42:293-296.
    • (2003) Eur. J. Nutr. , vol.42 , pp. 293-296
    • Sarkadi-Nagy, E.1    Huang, M.C.2    Diau, G.Y.3    Kirwan, R.4    Chueh Chao, A.5    Tschanz, C.6    Brenna, J.T.7
  • 31
    • 0030827459 scopus 로고    scopus 로고
    • Influence of long-term supplementation with alpha-linolenic acid on myocardial lipid peroxidation and antioxidative capacity in spontaneously hypertensive rats
    • Schimke, I., Haberland, A., Wirth, M., Papies, B., Moritz, V., and Baumann, G. 1997. Influence of long-term supplementation with alpha-linolenic acid on myocardial lipid peroxidation and antioxidative capacity in spontaneously hypertensive rats. Prostaglandins Leukotrienes Essential Fatty Acids 57:545-550.
    • (1997) Prostaglandins Leukotrienes Essential Fatty Acids , vol.57 , pp. 545-550
    • Schimke, I.1    Haberland, A.2    Wirth, M.3    Papies, B.4    Moritz, V.5    Baumann, G.6
  • 32
    • 0036200360 scopus 로고    scopus 로고
    • Diet enriched with omega-3 fatty acids alleviates convulsion symptoms in epilepsy patients
    • Schlanger, S., Shinitzky, M., and Yam, D. 2002. Diet enriched with omega-3 fatty acids alleviates convulsion symptoms in epilepsy patients. Epilepsia 43:103-104.
    • (2002) Epilepsia , vol.43 , pp. 103-104
    • Schlanger, S.1    Shinitzky, M.2    Yam, D.3
  • 33
    • 0025827312 scopus 로고
    • Erythrocyte defense against hydrogen peroxide: Preeminent importance of catalase
    • Scott, M. D., Lubin, B. H., Zuo, L., and Kuypers, F. A. 1991. Erythrocyte defense against hydrogen peroxide: Preeminent importance of catalase. J. Lab. Clin. Med. 118:7-16.
    • (1991) J. Lab. Clin. Med. , vol.118 , pp. 7-16
    • Scott, M.D.1    Lubin, B.H.2    Zuo, L.3    Kuypers, F.A.4
  • 34
    • 0034686664 scopus 로고    scopus 로고
    • Metabolism of highly unsaturated n-3 and n-6 fatty acids
    • Sprecher, H. 2000. Metabolism of highly unsaturated n-3 and n-6 fatty acids. Biochim. Biophys. Acta 1486:219-231.
    • (2000) Biochim. Biophys. Acta , vol.1486 , pp. 219-231
    • Sprecher, H.1
  • 35
    • 58149242571 scopus 로고    scopus 로고
    • Dosedependent anticonvulsant effects of linoleic and alpha-linolenic polyunsaturated fatty acids on pentylenetetrazol induced seizures in rats
    • Taha, A. Y., Filo, E., Ma, D. W., and McIntyre Burnham, W. 2009. Dosedependent anticonvulsant effects of linoleic and alpha-linolenic polyunsaturated fatty acids on pentylenetetrazol induced seizures in rats. Epilepsia 50:72-82.
    • (2009) Epilepsia , vol.50 , pp. 72-82
    • Taha, A.Y.1    Filo, E.2    Ma, D.W.3    McIntyre Burnham, W.4
  • 36
    • 41749121711 scopus 로고    scopus 로고
    • Seizure resistance in fat-1 transgenic mice endogenously synthesizing high levels of omega-3 polyunsaturated fatty acids
    • Taha, A. Y., Huot, P. S., Reza-Lopez, S., Prayitno, N. R., Kang, J. X., Burnham, W. M., and Ma, D. W. 2008. Seizure resistance in fat-1 transgenic mice endogenously synthesizing high levels of omega-3 polyunsaturated fatty acids. J. Neurochem. 105:380-388.
    • (2008) J. Neurochem. , vol.105 , pp. 380-388
    • Taha, A.Y.1    Huot, P.S.2    Reza-Lopez, S.3    Prayitno, N.R.4    Kang, J.X.5    Burnham, W.M.6    Ma, D.W.7
  • 37
    • 23944442745 scopus 로고    scopus 로고
    • Despite transient ketosis, the classic high-fat ketogenic diet induces marked changes in fatty acid metabolism in rats
    • Taha, A. Y., Ryan, M. A., and Cunnane, S. C. 2005. Despite transient ketosis, the classic high-fat ketogenic diet induces marked changes in fatty acid metabolism in rats. Metabolism 54:1127-1132.
    • (2005) Metabolism , vol.54 , pp. 1127-1132
    • Taha, A.Y.1    Ryan, M.A.2    Cunnane, S.C.3
  • 38
    • 0037411282 scopus 로고    scopus 로고
    • 4-Hydroxy-2-nonenal: A product and mediator of oxidative stress
    • Uchida, K. 2003. 4-Hydroxy-2-nonenal: A product and mediator of oxidative stress. Prog. Lipid Res. 42:318-343.
    • (2003) Prog. Lipid Res. , vol.42 , pp. 318-343
    • Uchida, K.1
  • 39
    • 0032509704 scopus 로고    scopus 로고
    • Anticonvulsant effect of polyunsaturated fatty acids in rats, using the cortical stimulation model
    • Voskuyl, R. A., Vreugdenhil, M., Kang, J. X., and Leaf, A. 1998. Anticonvulsant effect of polyunsaturated fatty acids in rats, using the cortical stimulation model. Eur. J. Pharmacol. 341:145-152.
    • (1998) Eur. J. Pharmacol. , vol.341 , pp. 145-152
    • Voskuyl, R.A.1    Vreugdenhil, M.2    Kang, J.X.3    Leaf, A.4
  • 41
    • 0032533744 scopus 로고    scopus 로고
    • Glutathione transferase protects neuronal cultures against four hydroxynonenal toxicity
    • Xie, C., Lovell, M. A., and Markesbery, W. R. 1998. Glutathione transferase protects neuronal cultures against four hydroxynonenal toxicity. Free Radical Biol. Med. 25:979-988.
    • (1998) Free Radical Biol. Med. , vol.25 , pp. 979-988
    • Xie, C.1    Lovell, M.A.2    Markesbery, W.R.3
  • 42
    • 0030239976 scopus 로고    scopus 로고
    • Essential fatty acid preparation reduces cholesterol and fatty acids in rat cortex
    • Yehuda, S., Brandys, Y., Blumenfeld, A., and Mostofsky, D. I. 1996. Essential fatty acid preparation reduces cholesterol and fatty acids in rat cortex. Int. J. Neurosci. 86:249-256.
    • (1996) Int. J. Neurosci. , vol.86 , pp. 249-256
    • Yehuda, S.1    Brandys, Y.2    Blumenfeld, A.3    Mostofsky, D.I.4
  • 43
    • 0028316790 scopus 로고
    • Essential fatty acid preparation (SR-3) raises the seizure threshold in rats
    • Yehuda, S., Carasso, R. L., and Mostofsky, D. I. 1994. Essential fatty acid preparation (SR-3) raises the seizure threshold in rats. Eur. J. Pharmacol. 254:193-198.
    • (1994) Eur. J. Pharmacol. , vol.254 , pp. 193-198
    • Yehuda, S.1    Carasso, R.L.2    Mostofsky, D.I.3
  • 44
    • 0033938160 scopus 로고    scopus 로고
    • Docosahexaenoic acid inhibits synaptic transmission and epileptiform activity in the rat hippocampus
    • Young, C., Gean, P. W., Chiou, L. C., and Shen, Y. Z. 2000. Docosahexaenoic acid inhibits synaptic transmission and epileptiform activity in the rat hippocampus. Synapse 37:90-94.
    • (2000) Synapse , vol.37 , pp. 90-94
    • Young, C.1    Gean, P.W.2    Chiou, L.C.3    Shen, Y.Z.4
  • 45
    • 1242296881 scopus 로고    scopus 로고
    • Is omega-3 fatty acid deficiency a factor contributing to refractory seizures and SUDEP? A hypothesis
    • Yuen, A. W., and Sander, J. W. 2004. Is omega-3 fatty acid deficiency a factor contributing to refractory seizures and SUDEP? A hypothesis. Seizure 13:104-107.
    • (2004) Seizure , vol.13 , pp. 104-107
    • Yuen, A.W.1    Sander, J.W.2
  • 47
    • 33749254101 scopus 로고    scopus 로고
    • 4-Hydroxy-2-nonenal upregulates endogenous antioxidants and phase 2 enzymes in rat H9c2 myocardiac cells: Protection against overt oxidative and electrophilic injury
    • Zhu, H., Zhang, L., Xi, X., Zweier, J. L., and Li, Y. 2006. 4-Hydroxy-2-nonenal upregulates endogenous antioxidants and phase 2 enzymes in rat H9c2 myocardiac cells: Protection against overt oxidative and electrophilic injury. Free Radical Res 40:875-884.
    • (2006) Free Radical Res , vol.40 , pp. 875-884
    • Zhu, H.1    Zhang, L.2    Xi, X.3    Zweier, J.L.4    Li, Y.5


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