Unaltered negative selection and Treg development of self-reactive thymocytes in TCR transgenic Fyn-deficient mice

European Journal of Immunology

Volumn 40, Issue 2, 2010, Pages 539-547

  Mamchak, Alusha A ^a   Thien, Christine B F ^b   Dagger, Samantha A ^b   Lyandres, Julia ^a   Jiang, Shuwei ^a   Langdon, Wallace Y ^b   DeFranco, Anthony L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

c Cbl; Fyn kinase; Negative selection; Thymic development; Treg

Indexed keywords

ADAPTOR PROTEIN; CBL PROTEIN; OVALBUMIN; PEPTIDE; PROTEIN KINASE FYN; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; FEMALE; IN VITRO STUDY; LYMPHOCYTE FUNCTION; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; THYMOCYTE; THYMUS; TRANSGENE; TRANSGENIC MOUSE;

ANIMALS; ANTIGENS; BLOTTING, WESTERN; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; FEMALE; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MUTATION; PROTO-ONCOGENE PROTEINS C-CBL; PROTO-ONCOGENE PROTEINS C-FYN; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES, REGULATORY; THYMUS GLAND;

EID: 75149121135     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200939645     Document Type: Article

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