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Volumn 139, Issue 2, 2010, Pages 319-330

Is the metalloendopeptidase EC 3.4.24.15 (EP24.15), the enzyme that cleaves luteinizing hormone-releasing hormone (LHRH), an activating enzyme?

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA NEOENDORPHIN; ANGIOTENSIN I; ANGIOTENSIN II; ARGIPRESSIN; BRADYKININ; CALCITONIN GENE RELATED PEPTIDE ALPHA; CALCITONIN GENE RELATED PEPTIDE BETA; DYNORPHIN A; DYNORPHIN B; GONADORELIN; GONADORELIN AGONIST; GONADORELIN DERIVATIVE; GONADORELIN RECEPTOR; INTERMEDIN; LEUPRORELIN; METALLOENDOPEPTIDASE EC 3.4.24.15; METALLOPROTEINASE; NEUROPEPTIDE; NOCICEPTIN; OXYTOCIN; PEPTIDE FRAGMENT; SUBSTANCE P; TAMOXIFEN; UNCLASSIFIED DRUG; VASOACTIVE INTESTINAL POLYPEPTIDE; ZINC;

EID: 75149116594     PISSN: 14701626     EISSN: 17417899     Source Type: Journal    
DOI: 10.1530/REP-09-0117     Document Type: Review
Times cited : (17)

References (125)
  • 1
    • 0023106913 scopus 로고
    • Synaptosomal membrane bound form of endopeptidase-24.15 generates Leu-enkephalin from dynorphin 1-8, alpha- and beta-neoendorphin, and Met-enkephalin from Met-enkephalin-Arg6-Gly7- Leu8
    • Acker GR, Molineaux C & Orlowski M 1987 Synaptosomal membrane bound form of endopeptidase-24.15 generates Leu-enkephalin from dynorphin 1-8, alpha- and beta-neoendorphin, and Met-enkephalin from Met-enkephalin-Arg6-Gly7- Leu8. Journal of Neurochemistry 48 284-292.
    • (1987) Journal of Neurochemistry , vol.48 , pp. 284-292
    • Acker, G.R.1    Molineaux, C.2    Orlowski, M.3
  • 2
    • 0034186201 scopus 로고    scopus 로고
    • Luteinizing hormone-releasing hormone as an autocrine growth factor in ES-2 ovarian cancer cell line
    • Arencibia JM & Schally AV 2000 Luteinizing hormone-releasing hormone as an autocrine growth factor in ES-2 ovarian cancer cell line. International Journal of Oncology 16 1009-1013.
    • (2000) International Journal of Oncology , vol.16 , pp. 1009-1013
    • Arencibia, J.M.1    Schally, A.V.2
  • 3
    • 0031671617 scopus 로고    scopus 로고
    • Expression of gonadotropin-releasing hormone (GnRH) and GnRH receptor mRNA in prostate cancer cells and effect of GnRH on the proliferation of prostate cancer cells
    • Bahk JY, Hyun JS, Lee H, Kim MO, Cho GJ, Lee BH & Choi WS 1998 Expression of gonadotropin-releasing hormone (GnRH) and GnRH receptor mRNA in prostate cancer cells and effect of GnRH on the proliferation of prostate cancer cells. Urological Research 26 259-264.
    • (1998) Urological Research , vol.26 , pp. 259-264
    • Bahk, J.Y.1    Hyun, J.S.2    Lee, H.3    Kim, M.O.4    Cho, G.J.5    Lee, B.H.6    Choi, W.S.7
  • 4
    • 33846173926 scopus 로고    scopus 로고
    • Regulation of type II luteinizing hormone-releasing hormone (LHRH-II) gene expression by the processed peptide of LHRH-I, LHRH-(1-5) in endometrial cells
    • Baldwin EL, Wegorzewska IN, Flora M & Wu TJ 2007 Regulation of type II luteinizing hormone-releasing hormone (LHRH-II) gene expression by the processed peptide of LHRH-I, LHRH-(1-5) in endometrial cells. Experimental Biology and Medicine 232 146-155.
    • (2007) Experimental Biology and Medicine , vol.232 , pp. 146-155
    • Baldwin, E.L.1    Wegorzewska, I.N.2    Flora, M.3    Wu, T.J.4
  • 5
    • 0036078657 scopus 로고    scopus 로고
    • Anxiolytic-like effects of substance P fragment (SP(1-7)) in non-human primates (Callithrix penicillata)
    • Barros M, De Souza Silva MA, Huston JP & Tomaz C 2002 Anxiolytic-like effects of substance P fragment (SP(1-7)) in non-human primates (Callithrix penicillata). Peptides 23 967-973.
    • (2002) Peptides , vol.23 , pp. 967-973
    • Barros, M.1    De Souza Silva, M.A.2    Huston, J.P.3    Tomaz, C.4
  • 6
    • 0018045663 scopus 로고
    • Peptide hormones and their analogues: Distribution, clearance from the circulation, and inactivation in vivo
    • Bennett HPJ & McMartin C 1979 Peptide hormones and their analogues: distribution, clearance from the circulation, and inactivation in vivo. Pharmacological Reviews 30 247.
    • (1979) Pharmacological Reviews , vol.30 , pp. 247
    • Bennett, H.P.J.1    McMartin, C.2
  • 7
    • 0142030054 scopus 로고    scopus 로고
    • Evidence for a role for vasoactive intestinal peptide in active vasodilatation in the cutaneous vasculature of humans
    • Bennett LA, Johnson JM, Stephens DP, Saad AR & Kellogg DL Jr 2003 Evidence for a role for vasoactive intestinal peptide in active vasodilatation in the cutaneous vasculature of humans. Journal of Physiology 552 223-232.
    • (2003) Journal of Physiology , vol.552 , pp. 223-232
    • Bennett, L.A.1    Johnson, J.M.2    Stephens, D.P.3    Saad, A.R.4    Kellogg Jr, D.L.5
  • 9
    • 23444432857 scopus 로고
    • Gonadotropin releasing hormone inhibitory autofeedback by subproducts antagonist at N-methyl-D-aspartate receptors: A model of autocrine regulation of peptide secretion
    • Bourguignon JP, Alvarez Gonzalez ML, Gerard A & Franchimont P 1994 Gonadotropin releasing hormone inhibitory autofeedback by subproducts antagonist at N-methyl-D-aspartate receptors: a model of autocrine regulation of peptide secretion. Endocrinology 134 1589-1592.
    • (1994) Endocrinology , vol.134 , pp. 1589-1592
    • Bourguignon, J.P.1    Alvarez Gonzalez, M.L.2    Gerard, A.3    Franchimont, P.4
  • 10
    • 0022414414 scopus 로고
    • Specific binding of gonadotrophin-releasing hormone and an agonist to human corpus luteum homogenates: Characterization, properties, and luteal phase levels
    • Bramley TA, Menzies GS & Baird DT 1985 Specific binding of gonadotrophin-releasing hormone and an agonist to human corpus luteum homogenates: characterization, properties, and luteal phase levels. Journal of Clinical Endocrinology and Metabolism 61 834-841.
    • (1985) Journal of Clinical Endocrinology and Metabolism , vol.61 , pp. 834-841
    • Bramley, T.A.1    Menzies, G.S.2    Baird, D.T.3
  • 12
    • 0034456330 scopus 로고    scopus 로고
    • Human oviductal gonadotropin-releasing hormone: Possible implications in fertilization, early embryonic development, and implantation
    • Casan EM, Raga F, Bonilla-Musoles F & Polan ML 2000 Human oviductal gonadotropin-releasing hormone: possible implications in fertilization, early embryonic development, and implantation. Journal of Clinical Endocrinology and Metabolism 85 1377-1381.
    • (2000) Journal of Clinical Endocrinology and Metabolism , vol.85 , pp. 1377-1381
    • Casan, E.M.1    Raga, F.2    Bonilla-Musoles, F.3    Polan, M.L.4
  • 13
    • 3242695312 scopus 로고    scopus 로고
    • Novel aspects of the renal renin-angiotensin system: Angiotensin-(1-7), ACE2 and blood pressure regulation
    • Chappell MC, Modrall JG, Diz DI & Ferrario CM 2004 Novel aspects of the renal renin-angiotensin system: angiotensin-(1-7), ACE2 and blood pressure regulation. Contributions to Nephrology 143 77-89.
    • (2004) Contributions to Nephrology , vol.143 , pp. 77-89
    • Chappell, M.C.1    Modrall, J.G.2    Diz, D.I.3    Ferrario, C.M.4
  • 14
    • 33751511183 scopus 로고    scopus 로고
    • Immunolocalization of gonadotropin-releasing hormone (GnRH)-I, GnRH-II, and type I GnRH receptor during follicular development in the human ovary
    • Choi JH, Gilks CB, Auersperg N & Leung PC 2006 Immunolocalization of gonadotropin-releasing hormone (GnRH)-I, GnRH-II, and type I GnRH receptor during follicular development in the human ovary. Journal of Clinical Endocrinology and Metabolism 91 4562-4570.
    • (2006) Journal of Clinical Endocrinology and Metabolism , vol.91 , pp. 4562-4570
    • Choi, J.H.1    Gilks, C.B.2    Auersperg, N.3    Leung, P.C.4
  • 15
    • 1642336425 scopus 로고    scopus 로고
    • Cellular localization of gonadotropin-releasing hormone (GnRH) I and GnRH II in first-trimester human placenta and decidua
    • Chou CS, Beristain AG, MacCalman CD & Leung PC 2004 Cellular localization of gonadotropin-releasing hormone (GnRH) I and GnRH II in first-trimester human placenta and decidua. Journal of Clinical Endocrinology and Metabolism 89 1459-1466.
    • (2004) Journal of Clinical Endocrinology and Metabolism , vol.89 , pp. 1459-1466
    • Chou, C.S.1    Beristain, A.G.2    MacCalman, C.D.3    Leung, P.C.4
  • 16
    • 0026496128 scopus 로고
    • Rat granulosa cells express the gonadotropin-releasing hormone gene: Evidence from in situ hybridisation
    • Clayton RN, Eccleston L, Gossard F & Morel G 1992 Rat granulosa cells express the gonadotropin-releasing hormone gene: evidence from in situ hybridisation. Journal of Molecular Endocrinology 9 189-195.
    • (1992) Journal of Molecular Endocrinology , vol.9 , pp. 189-195
    • Clayton, R.N.1    Eccleston, L.2    Gossard, F.3    Morel, G.4
  • 18
    • 0033600514 scopus 로고    scopus 로고
    • Crack PJ, Wu TJ, Cummins PM, Ferro ES, Tullai JW, Glucksman MJ & Roberts JL 1999 The association of metalloendopeptidase EC 3.4.24.15 at the extracellular surface of the AtT-20 cell plasma membrane. Brain Research 835 113-124.
    • Crack PJ, Wu TJ, Cummins PM, Ferro ES, Tullai JW, Glucksman MJ & Roberts JL 1999 The association of metalloendopeptidase EC 3.4.24.15 at the extracellular surface of the AtT-20 cell plasma membrane. Brain Research 835 113-124.
  • 19
    • 0033523012 scopus 로고    scopus 로고
    • Zinc coordination and substrate catalysis within the neuropeptide processing enzyme endopeptidase EC 3.4.24.15. Identification of active site histidine and glutamate residues
    • Cummins PM, Pabon A, Margulies EH & Glucksman MJ 1999 Zinc coordination and substrate catalysis within the neuropeptide processing enzyme endopeptidase EC 3.4.24.15. Identification of active site histidine and glutamate residues. Journal of Biological Chemistry 274 16003-16009.
    • (1999) Journal of Biological Chemistry , vol.274 , pp. 16003-16009
    • Cummins, P.M.1    Pabon, A.2    Margulies, E.H.3    Glucksman, M.J.4
  • 21
    • 0026760229 scopus 로고
    • Purification of the main somatostatin degrading proteases from rat and pig brains, their action on other neuropeptides and their identification as endopeptidases 24.15 and 24.16
    • Dahms P & Mentlein R 1992 Purification of the main somatostatin degrading proteases from rat and pig brains, their action on other neuropeptides and their identification as endopeptidases 24.15 and 24.16. European Journal of Biochemistry 208 145-154.
    • (1992) European Journal of Biochemistry , vol.208 , pp. 145-154
    • Dahms, P.1    Mentlein, R.2
  • 22
    • 0020405931 scopus 로고
    • Influence of the carboxyl terminus of luteinizing hormone-releasing hormone and bradykinin on hydrolysis by brain endo-oligopeptidases
    • De Camargo AC, Da Fonseca MJ, Caldo H & De Morais Carvalho K 1982 Influence of the carboxyl terminus of luteinizing hormone-releasing hormone and bradykinin on hydrolysis by brain endo-oligopeptidases. Journal of Biological Chemistry 257 9265-9267.
    • (1982) Journal of Biological Chemistry , vol.257 , pp. 9265-9267
    • De Camargo, A.C.1    Da Fonseca, M.J.2    Caldo, H.3    De Morais Carvalho, K.4
  • 23
    • 85003156705 scopus 로고
    • Identification of a major up-stream transcription start site for the human progonadotropin-releasing hormone gene used in reproductive tissues and cell lines
    • Dong KW, Yu KL & Roberts JL 1993 Identification of a major up-stream transcription start site for the human progonadotropin-releasing hormone gene used in reproductive tissues and cell lines. Molecular Endocrinology 7 1654-1666.
    • (1993) Molecular Endocrinology , vol.7 , pp. 1654-1666
    • Dong, K.W.1    Yu, K.L.2    Roberts, J.L.3
  • 24
    • 0028235123 scopus 로고
    • The use of luteinizing hormone releasing hormone agonists and antagonists in gynecological cancers
    • Emons G & Schally AV 1994 The use of luteinizing hormone releasing hormone agonists and antagonists in gynecological cancers. Human Reproduction 9 1364-1379.
    • (1994) Human Reproduction , vol.9 , pp. 1364-1379
    • Emons, G.1    Schally, A.V.2
  • 25
    • 0024950999 scopus 로고
    • Characteristics and distribution of receptors for [D-Trp6]-luteinizing hormone-releasing hormone, somatostatin, epidermal growth factor and sex steroids in 500 biopsy samples of human breast cancer
    • Fekete M, Wittliff JL & Schally AV 1989 Characteristics and distribution of receptors for [D-Trp6]-luteinizing hormone-releasing hormone, somatostatin, epidermal growth factor and sex steroids in 500 biopsy samples of human breast cancer. Journal of Clinical Laboratory Analysis 3 137-147.
    • (1989) Journal of Clinical Laboratory Analysis , vol.3 , pp. 137-147
    • Fekete, M.1    Wittliff, J.L.2    Schally, A.V.3
  • 26
    • 57449120247 scopus 로고    scopus 로고
    • Cognitive-enhancing effects of angiotensin IV
    • Gard PR 2008 Cognitive-enhancing effects of angiotensin IV. BMC Neuroscience 9 S15.
    • (2008) BMC Neuroscience , vol.9
    • Gard, P.R.1
  • 27
    • 19944405794 scopus 로고    scopus 로고
    • Evidence that prostate gonadotropin-releasing hormone receptors mediate an anti-tumourigenic response to analogue therapy in hormone refractory prostate cancer
    • Gnanapragasam VJ, Darby S, Khan MM, Lock WG, Robson CN & Leung HY 2005 Evidence that prostate gonadotropin-releasing hormone receptors mediate an anti-tumourigenic response to analogue therapy in hormone refractory prostate cancer. Journal of Pathology 206 205-213.
    • (2005) Journal of Pathology , vol.206 , pp. 205-213
    • Gnanapragasam, V.J.1    Darby, S.2    Khan, M.M.3    Lock, W.G.4    Robson, C.N.5    Leung, H.Y.6
  • 29
    • 0035020249 scopus 로고    scopus 로고
    • Antiproliferative signaling of luteinizing hormone-releasing hormone in human endometrial and ovarian cancer cells through G protein alpha(I)-mediated activation of phosphotyrosine phosphatase
    • Grundker C, Volker P & Emons G 2001 Antiproliferative signaling of luteinizing hormone-releasing hormone in human endometrial and ovarian cancer cells through G protein alpha(I)-mediated activation of phosphotyrosine phosphatase. Endocrinology 142 2369-2380.
    • (2001) Endocrinology , vol.142 , pp. 2369-2380
    • Grundker, C.1    Volker, P.2    Emons, G.3
  • 30
    • 0022668268 scopus 로고
    • Pharmacokinetics of gonadotropin-releasing hormone and its analogs
    • Handelsman DJ & Swerdloff RS 1986 Pharmacokinetics of gonadotropin-releasing hormone and its analogs. Endocrine Reviews 7 95-105.
    • (1986) Endocrine Reviews , vol.7 , pp. 95-105
    • Handelsman, D.J.1    Swerdloff, R.S.2
  • 31
    • 0025856681 scopus 로고
    • Gonadotropin-releasing hormone gene expression in MDA-MB-231 and ZR-75-1 breast carcinoma cell lines
    • Harris N, Dutlow C, Eidne K, Dong KW, Roberts J & Millar R 1991 Gonadotropin-releasing hormone gene expression in MDA-MB-231 and ZR-75-1 breast carcinoma cell lines. Cancer Research 51 2577-2581.
    • (1991) Cancer Research , vol.51 , pp. 2577-2581
    • Harris, N.1    Dutlow, C.2    Eidne, K.3    Dong, K.W.4    Roberts, J.5    Millar, R.6
  • 32
  • 33
    • 0029814343 scopus 로고    scopus 로고
    • Bradykinin and its metabolite, Arg-Pro-Pro-Gly-Phe, are selective inhibitors of alpha-thrombin-induced platelet activation
    • Hasan AA, Amenta S & Schmaier AH 1996 Bradykinin and its metabolite, Arg-Pro-Pro-Gly-Phe, are selective inhibitors of alpha-thrombin-induced platelet activation. Circulation 94 517-528.
    • (1996) Circulation , vol.94 , pp. 517-528
    • Hasan, A.A.1    Amenta, S.2    Schmaier, A.H.3
  • 35
    • 0020389552 scopus 로고
    • Regulation of ovarian granulosa luteal cell functions by gonadotropin releasing hormone and its antagonist
    • Hsueh AJ & Jones PB 1982 Regulation of ovarian granulosa luteal cell functions by gonadotropin releasing hormone and its antagonist. Advanced Experimental Medical Biology 147 223-262.
    • (1982) Advanced Experimental Medical Biology , vol.147 , pp. 223-262
    • Hsueh, A.J.1    Jones, P.B.2
  • 36
    • 0028873829 scopus 로고
    • The role of neuropeptides in learning: Focus on the neurokinin substance P
    • Huston JP & Hasenöhrl RU 1995 The role of neuropeptides in learning: focus on the neurokinin substance P. Behavioral Brain Research 66 117-127.
    • (1995) Behavioral Brain Research , vol.66 , pp. 117-127
    • Huston, J.P.1    Hasenöhrl, R.U.2
  • 38
    • 0027944974 scopus 로고
    • Presence of gonadotropin-releasing hormone receptor and its messenger ribonucleic acid in endometrial carcinoma and endometrium
    • Imai A, Ohno T, Iida K, Fuseya T, Furui T & Tamaya T 1994 Presence of gonadotropin-releasing hormone receptor and its messenger ribonucleic acid in endometrial carcinoma and endometrium. Gynecologic Oncology 55 114-118.
    • (1994) Gynecologic Oncology , vol.55 , pp. 114-118
    • Imai, A.1    Ohno, T.2    Iida, K.3    Fuseya, T.4    Furui, T.5    Tamaya, T.6
  • 40
    • 0031804790 scopus 로고    scopus 로고
    • Fas and Fas ligand system may mediate antiproliferative activity of gonadotropin- releasing hormone receptor in endometrial cancer cells
    • Imai A, Takagi A, Horibe S, Takagi H & Tamaya T 1998 Fas and Fas ligand system may mediate antiproliferative activity of gonadotropin- releasing hormone receptor in endometrial cancer cells. International Journal of Oncology 13 97-100.
    • (1998) International Journal of Oncology , vol.13 , pp. 97-100
    • Imai, A.1    Takagi, A.2    Horibe, S.3    Takagi, H.4    Tamaya, T.5
  • 42
    • 0028854196 scopus 로고
    • Expression of the messenger RNAs for luteinizing hormone-releasing hormone (LHRH) and its receptor in human ovarian epithelial carcinoma
    • Irmer G, Bürger C, Müller R, Ortmann O, Peter U, Kakar SS, Neill JD, Schulz KD & Emons G 1995 Expression of the messenger RNAs for luteinizing hormone-releasing hormone (LHRH) and its receptor in human ovarian epithelial carcinoma. Cancer Research 55 817-822.
    • (1995) Cancer Research , vol.55 , pp. 817-822
    • Irmer, G.1    Bürger, C.2    Müller, R.3    Ortmann, O.4    Peter, U.5    Kakar, S.S.6    Neill, J.D.7    Schulz, K.D.8    Emons, G.9
  • 43
    • 4143066846 scopus 로고    scopus 로고
    • Metalloendopeptidase EC3.4.24.15 is constitutively released from the exofacial leaflet of lipid rafts in GT1-7 cells
    • Jeske NA, Glucksman MJ & Roberts JL 2004 Metalloendopeptidase EC3.4.24.15 is constitutively released from the exofacial leaflet of lipid rafts in GT1-7 cells. Journal of Neurochemistry 90 819-828.
    • (2004) Journal of Neurochemistry , vol.90 , pp. 819-828
    • Jeske, N.A.1    Glucksman, M.J.2    Roberts, J.L.3
  • 45
    • 0032032276 scopus 로고    scopus 로고
    • Inhibition of the growth of Caki-I human renal adenocarcinoma in vivo by luteinizing hormone-releasing hormone antagonist Cetrorelix, somatostatin analog RC-160, and bombesin antagonist RC-3940-II
    • Jungwirth A, Schally AV, Halmos G, Groot K, Szepeshazi K, Pinski J & Armatis P 1998 Inhibition of the growth of Caki-I human renal adenocarcinoma in vivo by luteinizing hormone-releasing hormone antagonist Cetrorelix, somatostatin analog RC-160, and bombesin antagonist RC-3940-II. Cancer 82 909-917.
    • (1998) Cancer , vol.82 , pp. 909-917
    • Jungwirth, A.1    Schally, A.V.2    Halmos, G.3    Groot, K.4    Szepeshazi, K.5    Pinski, J.6    Armatis, P.7
  • 46
    • 0028586112 scopus 로고
    • The nucleotide sequences of human GnRH receptors in breast and ovarian tumors are identical with that found in pituitary
    • Kakar SS, Grizzle WE & Neill JD 1994 The nucleotide sequences of human GnRH receptors in breast and ovarian tumors are identical with that found in pituitary. Molecular and Cellular Endocrinology 106 145-149.
    • (1994) Molecular and Cellular Endocrinology , vol.106 , pp. 145-149
    • Kakar, S.S.1    Grizzle, W.E.2    Neill, J.D.3
  • 48
    • 21344469076 scopus 로고    scopus 로고
    • Human malignant melanomas express receptors for luteinizing hormone releasing hormone allowing targeted therapy with cytotoxic luteinizing hormone releasing hormone analogue
    • Keller G, Schally AV, Gaiser T, Nagy A, Baker B, Westphal G, Halmos G & Engel JB 2005 Human malignant melanomas express receptors for luteinizing hormone releasing hormone allowing targeted therapy with cytotoxic luteinizing hormone releasing hormone analogue. Cancer Research 65 5857-5863.
    • (2005) Cancer Research , vol.65 , pp. 5857-5863
    • Keller, G.1    Schally, A.V.2    Gaiser, T.3    Nagy, A.4    Baker, B.5    Westphal, G.6    Halmos, G.7    Engel, J.B.8
  • 50
    • 0035862149 scopus 로고    scopus 로고
    • Combined tamoxifen and luteinizing hormone-releasing hormone (LHRH) agonist versus LHRH agonist alone in premenopausal advanced breast cancer: A meta-analysis of four randomized trials
    • Klijn JG, Blamey RW, Boccardo F, Tominaga T, Duchateau L & Sylvester R 2001 Combined tamoxifen and luteinizing hormone-releasing hormone (LHRH) agonist versus LHRH agonist alone in premenopausal advanced breast cancer: a meta-analysis of four randomized trials. Journal of Clinical Oncology 19 343-353.
    • (2001) Journal of Clinical Oncology , vol.19 , pp. 343-353
    • Klijn, J.G.1    Blamey, R.W.2    Boccardo, F.3    Tominaga, T.4    Duchateau, L.5    Sylvester, R.6
  • 51
    • 0029905264 scopus 로고    scopus 로고
    • Drug addiction: The yin and yang of hedonic homeostasis
    • Koob GF 1996 Drug addiction: the yin and yang of hedonic homeostasis. Neuron 16 893-896.
    • (1996) Neuron , vol.16 , pp. 893-896
    • Koob, G.F.1
  • 52
    • 0030923675 scopus 로고    scopus 로고
    • The genes for gonadotropin-releasing hormone and its receptor are expressed in human breast with fibrocystic disease and cancer
    • Kottler ML, Starzec A, Carre MC, Lagarde JP, Martin A & Counis R 1997 The genes for gonadotropin-releasing hormone and its receptor are expressed in human breast with fibrocystic disease and cancer. International Journal of Cancer 71 595-599.
    • (1997) International Journal of Cancer , vol.71 , pp. 595-599
    • Kottler, M.L.1    Starzec, A.2    Carre, M.C.3    Lagarde, J.P.4    Martin, A.5    Counis, R.6
  • 54
    • 0030426798 scopus 로고    scopus 로고
    • The substance P amino-terminal metabolite substance P(1-7), administered peripherally, prevents the development of acute morphine tolerance and attenuates the expression of withdrawal in mice
    • Kreeger JS & Larson AA 1996 The substance P amino-terminal metabolite substance P(1-7), administered peripherally, prevents the development of acute morphine tolerance and attenuates the expression of withdrawal in mice. Journal of Pharmacology and Experimental Therapeutics 279 662-667.
    • (1996) Journal of Pharmacology and Experimental Therapeutics , vol.279 , pp. 662-667
    • Kreeger, J.S.1    Larson, A.A.2
  • 60
    • 0018564981 scopus 로고
    • Substance P as neurogenic mediator of antidromic vasodilation and neurogenic plasma extravasation
    • Lembeck F & Holzer P 1979 Substance P as neurogenic mediator of antidromic vasodilation and neurogenic plasma extravasation. Naunyn-Schmiedeberg's Archives of Pharmacology 310 175-183.
    • (1979) Naunyn-Schmiedeberg's Archives of Pharmacology , vol.310 , pp. 175-183
    • Lembeck, F.1    Holzer, P.2
  • 62
    • 0028272080 scopus 로고
    • Evidence for a two-step mechanism of gonadotropin-releasing hormone metabolism by prolyl endopeptidase and metalloendopeptidase EC 3.4.24.15 in ovine hypothalamic extracts
    • Lew RA, Tetaz TJ, Glucksman MJ, Roberts JL & Smith AI 1994 Evidence for a two-step mechanism of gonadotropin-releasing hormone metabolism by prolyl endopeptidase and metalloendopeptidase EC 3.4.24.15 in ovine hypothalamic extracts. Journal of Biological Chemistry 269 12626-12632.
    • (1994) Journal of Biological Chemistry , vol.269 , pp. 12626-12632
    • Lew, R.A.1    Tetaz, T.J.2    Glucksman, M.J.3    Roberts, J.L.4    Smith, A.I.5
  • 64
    • 0026716297 scopus 로고
    • Antiproliferative effects of luteinizing hormone-releasing hormone agonists on the human prostatic cancer cell line LNCaP
    • Limonta P, Dondi D, Moretti RM, Maggi R & Motta M 1992 Antiproliferative effects of luteinizing hormone-releasing hormone agonists on the human prostatic cancer cell line LNCaP. Journal of Clinical Endocrinology and Metabolism 75 207-212.
    • (1992) Journal of Clinical Endocrinology and Metabolism , vol.75 , pp. 207-212
    • Limonta, P.1    Dondi, D.2    Moretti, R.M.3    Maggi, R.4    Motta, M.5
  • 66
    • 0033303530 scopus 로고    scopus 로고
    • The luteinizing hormone-releasing hormone receptor in human prostate cancer cells: Messenger ribonucleic acid expression, molecular size, signal transduction pathway
    • Limonta P, Moretti RM, Marelli MM, Dondi D, Parenti M & Motta M 1999 The luteinizing hormone-releasing hormone receptor in human prostate cancer cells: messenger ribonucleic acid expression, molecular size, signal transduction pathway. Endocrinology 140 5250-5256.
    • (1999) Endocrinology , vol.140 , pp. 5250-5256
    • Limonta, P.1    Moretti, R.M.2    Marelli, M.M.3    Dondi, D.4    Parenti, M.5    Motta, M.6
  • 67
    • 0347320615 scopus 로고    scopus 로고
    • The biology of gonadotropin hormone-releasing hormone: Role in the control of tumor growth and progression in humans
    • Limonta P, Moretti RM, Marelli MM & Motta M 2003 The biology of gonadotropin hormone-releasing hormone: role in the control of tumor growth and progression in humans. Frontiers in Neuroendocrinology 24 279-295.
    • (2003) Frontiers in Neuroendocrinology , vol.24 , pp. 279-295
    • Limonta, P.1    Moretti, R.M.2    Marelli, M.M.3    Motta, M.4
  • 68
    • 0028934499 scopus 로고
    • Growth inhibition of human prostate tumor cells by an agonist of gonadotrophin-releasing hormone
    • Loop SM, Gorder CA, Lewis SM, Saiers JH, Drivdahl RH & Ostenson RC 1995 Growth inhibition of human prostate tumor cells by an agonist of gonadotrophin-releasing hormone. Prostate 26 179-188.
    • (1995) Prostate , vol.26 , pp. 179-188
    • Loop, S.M.1    Gorder, C.A.2    Lewis, S.M.3    Saiers, J.H.4    Drivdahl, R.H.5    Ostenson, R.C.6
  • 69
    • 0031553387 scopus 로고    scopus 로고
    • Nociceptin/orphanin FQ and the opioid receptor-like ORL1 receptor
    • Meunier JC 1997 Nociceptin/orphanin FQ and the opioid receptor-like ORL1 receptor. European Journal of Pharmacology 340 1-15.
    • (1997) European Journal of Pharmacology , vol.340 , pp. 1-15
    • Meunier, J.C.1
  • 72
    • 0029024201 scopus 로고
    • Gonadotropin-releasing hormone antagonist versus agonist administration in women undergoing controlled ovarian hyperstimulation: Cycle performance and in vitro steroidogenesis of granulosa-lutein cells
    • Minaretzis D, Alper MM, Oskowitz SP, Lobel SM, Mortola JF & Pavlou SN 1995 Gonadotropin-releasing hormone antagonist versus agonist administration in women undergoing controlled ovarian hyperstimulation: cycle performance and in vitro steroidogenesis of granulosa-lutein cells. American Journal of Obstetrics and Gynecology 172 1518-1525.
    • (1995) American Journal of Obstetrics and Gynecology , vol.172 , pp. 1518-1525
    • Minaretzis, D.1    Alper, M.M.2    Oskowitz, S.P.3    Lobel, S.M.4    Mortola, J.F.5    Pavlou, S.N.6
  • 73
    • 0031037197 scopus 로고    scopus 로고
    • Nociceptin/orphanin FQ metabolism: Role of aminopeptidase and endopeptidase 24.15
    • Montiel JL, Cornille F, Roques BP & Noble F 1997 Nociceptin/orphanin FQ metabolism: role of aminopeptidase and endopeptidase 24.15. Journal of Neurochemistry 68 354-361.
    • (1997) Journal of Neurochemistry , vol.68 , pp. 354-361
    • Montiel, J.L.1    Cornille, F.2    Roques, B.P.3    Noble, F.4
  • 76
    • 0028850040 scopus 로고
    • Immunolocalization of a gonadotropin-releasing hormone receptor site in murine endometrium that mediates apoptosis
    • Murdoch WJ 1995 Immunolocalization of a gonadotropin-releasing hormone receptor site in murine endometrium that mediates apoptosis. Cell and Tissue Research 282 527-529.
    • (1995) Cell and Tissue Research , vol.282 , pp. 527-529
    • Murdoch, W.J.1
  • 77
    • 0034702913 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme insertion/deletion polymorphism modulates the human in vivo metabolism of bradykinin
    • Murphey LJ, Gainer JV, Vaughan DE & Brown NJ 2000 Angiotensin-converting enzyme insertion/deletion polymorphism modulates the human in vivo metabolism of bradykinin. Circulation 102 829-832.
    • (2000) Circulation , vol.102 , pp. 829-832
    • Murphey, L.J.1    Gainer, J.V.2    Vaughan, D.E.3    Brown, N.J.4
  • 80
    • 0344759125 scopus 로고    scopus 로고
    • Calcitonin gene-related peptide gene expression in collagen-induced arthritis is differentially regulated in primary afferents and motoneurons: Influence of glucocorticoids
    • Nohr D, Schäfer MK, Persson S, Romeo H, Nyberg F, Post C, Ekström G & Weihe E 1999 Calcitonin gene-related peptide gene expression in collagen-induced arthritis is differentially regulated in primary afferents and motoneurons: influence of glucocorticoids. Neuroscience 93 759-773.
    • (1999) Neuroscience , vol.93 , pp. 759-773
    • Nohr, D.1    Schäfer, M.K.2    Persson, S.3    Romeo, H.4    Nyberg, F.5    Post, C.6    Ekström, G.7    Weihe, E.8
  • 82
    • 0025761321 scopus 로고
    • Purification and characterization of endoproteases from human choroid plexus cleaving prodynorphin-derived opioid peptides
    • Nyberg F, Kankaanranta S, Brostedt P & Silberring J 1991 Purification and characterization of endoproteases from human choroid plexus cleaving prodynorphin-derived opioid peptides. Brain Research 552 129-135.
    • (1991) Brain Research , vol.552 , pp. 129-135
    • Nyberg, F.1    Kankaanranta, S.2    Brostedt, P.3    Silberring, J.4
  • 83
    • 0027369367 scopus 로고
    • Presence of gonadotropin-releasing hormone and its messenger ribonucleic acid in human ovarian epithelial carcinoma
    • Ohno T, Imai A, Furui T, Takahashi K & Tamaya T 1993 Presence of gonadotropin-releasing hormone and its messenger ribonucleic acid in human ovarian epithelial carcinoma. American Journal of Obstetrics and Gynecology 169 605-610.
    • (1993) American Journal of Obstetrics and Gynecology , vol.169 , pp. 605-610
    • Ohno, T.1    Imai, A.2    Furui, T.3    Takahashi, K.4    Tamaya, T.5
  • 84
    • 0020824984 scopus 로고
    • A soluble metalloendopeptidase from rat brain. Purification of the enzyme and determination of specificity with synthetic and natural peptides
    • Orlowski M, Michaud C & Chu TG 1983 A soluble metalloendopeptidase from rat brain. Purification of the enzyme and determination of specificity with synthetic and natural peptides. European Journal of Biochemistry 135 81-88.
    • (1983) European Journal of Biochemistry , vol.135 , pp. 81-88
    • Orlowski, M.1    Michaud, C.2    Chu, T.G.3
  • 85
    • 0024406166 scopus 로고
    • Endopeptidase 24.15 from rat testes. Isolation of the enzyme and its specificity toward synthetic and natural peptides, including enkephalin-containing peptides
    • Orlowski M, Reznik S, Ayala J & Pierotti AR 1989 Endopeptidase 24.15 from rat testes. Isolation of the enzyme and its specificity toward synthetic and natural peptides, including enkephalin-containing peptides. Biochemical Journal 261 951-958.
    • (1989) Biochemical Journal , vol.261 , pp. 951-958
    • Orlowski, M.1    Reznik, S.2    Ayala, J.3    Pierotti, A.R.4
  • 86
    • 0028148727 scopus 로고
    • Expression and regulatin of gonadotropin-releasing hormone (GnRH) and GnRH receptor messenger ribonucleic acids in human granulose-luteal cells
    • Peng C, Fan NC, Ligier M, Vannanen J & Leung PCK 1994 Expression and regulatin of gonadotropin-releasing hormone (GnRH) and GnRH receptor messenger ribonucleic acids in human granulose-luteal cells. Endocrinology 135 1740-1746.
    • (1994) Endocrinology , vol.135 , pp. 1740-1746
    • Peng, C.1    Fan, N.C.2    Ligier, M.3    Vannanen, J.4    Leung, P.C.K.5
  • 89
    • 0028582048 scopus 로고
    • Leuprorelin. A review of its pharmacology and therapeutic use in prostatic cancer, endometriosis and other sex hormone-related disorders
    • Plosker GL & Brogden RN 1994 Leuprorelin. A review of its pharmacology and therapeutic use in prostatic cancer, endometriosis and other sex hormone-related disorders. Drugs 48 930-967.
    • (1994) Drugs , vol.48 , pp. 930-967
    • Plosker, G.L.1    Brogden, R.N.2
  • 91
    • 0031828974 scopus 로고    scopus 로고
    • Quantitative gonadotropin-releasing hormone gene expression and immunohistochemical localization in human endometrium throughout the menstrual cycle
    • Raga F, Casañ EM, Kruessel JS, Wen Y, Huang HY, Nezhat C & Polan ML 1998 Quantitative gonadotropin-releasing hormone gene expression and immunohistochemical localization in human endometrium throughout the menstrual cycle. Biology of Reproduction 59 661-669.
    • (1998) Biology of Reproduction , vol.59 , pp. 661-669
    • Raga, F.1    Casañ, E.M.2    Kruessel, J.S.3    Wen, Y.4    Huang, H.Y.5    Nezhat, C.6    Polan, M.L.7
  • 94
    • 2442517311 scopus 로고    scopus 로고
    • Crystal structure of human thimet oligopeptidase provides insight into substrate recognition, regulation, and localization
    • Ray K, Hines CS, Coll-Rodriguez J & Rodgers DW 2004 Crystal structure of human thimet oligopeptidase provides insight into substrate recognition, regulation, and localization. Journal of Biological Chemistry 279 20480-20489.
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 20480-20489
    • Ray, K.1    Hines, C.S.2    Coll-Rodriguez, J.3    Rodgers, D.W.4
  • 96
    • 0038024648 scopus 로고    scopus 로고
    • Sampaio WO, Nascimento AA & Santos RA 2003 Systemic and regional hemodynamic effects of angiotensin-(1-7) in rats. American Journal of Physiology. Heart and Circulatory Physiology 284 H1985-H1994.
    • Sampaio WO, Nascimento AA & Santos RA 2003 Systemic and regional hemodynamic effects of angiotensin-(1-7) in rats. American Journal of Physiology. Heart and Circulatory Physiology 284 H1985-H1994.
  • 97
    • 42649115768 scopus 로고    scopus 로고
    • Recent advances in the angiotensin-converting enzyme 2-angiotensin(1-7)-Mas axis
    • Santos RA, Ferreira AJ & Simões E Silva AC 2008 Recent advances in the angiotensin-converting enzyme 2-angiotensin(1-7)-Mas axis. Experimental Physiology 93 519-527.
    • (2008) Experimental Physiology , vol.93 , pp. 519-527
    • Santos, R.A.1    Ferreira, A.J.2    Simões, E.3    Silva, A.C.4
  • 98
    • 0032739426 scopus 로고    scopus 로고
    • Luteinizing hormone-releasing hormone analogs: Their impact on the control of tumorigenesis
    • Schally AV 1999 Luteinizing hormone-releasing hormone analogs: their impact on the control of tumorigenesis. Peptides 20 1247-1262.
    • (1999) Peptides , vol.20 , pp. 1247-1262
    • Schally, A.V.1
  • 100
    • 33746915125 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone (GnRH) and its natural analogues: A review
    • Schneider F, Tomek W & Grundker C 2006 Gonadotropin-releasing hormone (GnRH) and its natural analogues: a review. Theriogenology 66 691-709.
    • (2006) Theriogenology , vol.66 , pp. 691-709
    • Schneider, F.1    Tomek, W.2    Grundker, C.3
  • 101
    • 0027495531 scopus 로고
    • Evidence that substance P is utilized in medial amygdaloid facilitation of defensive rage behavior in the cat
    • Shaikh MB, Steinberg A & Siegel A 1993 Evidence that substance P is utilized in medial amygdaloid facilitation of defensive rage behavior in the cat. Brain Research 625 283-294.
    • (1993) Brain Research , vol.625 , pp. 283-294
    • Shaikh, M.B.1    Steinberg, A.2    Siegel, A.3
  • 102
    • 0024465416 scopus 로고
    • Captopril and capsaicin modify opioid withdrawal in the morphine-dependent rat
    • Sharpe LG & Jaffe JH 1989 Captopril and capsaicin modify opioid withdrawal in the morphine-dependent rat. Pharmacology, Biochemistry, and Behavior 33 899-902.
    • (1989) Pharmacology, Biochemistry, and Behavior , vol.33 , pp. 899-902
    • Sharpe, L.G.1    Jaffe, J.H.2
  • 103
    • 0021175531 scopus 로고
    • Hydrolysis of substance P and neurotensin by converting enzyme and neutral endopeptidase
    • Skidgel RA, Engelbrecht S, Johnson AR & Erdös EG 1984 Hydrolysis of substance P and neurotensin by converting enzyme and neutral endopeptidase. Peptides 5 769-776.
    • (1984) Peptides , vol.5 , pp. 769-776
    • Skidgel, R.A.1    Engelbrecht, S.2    Johnson, A.R.3    Erdös, E.G.4
  • 107
    • 0035371234 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone receptor expression in the human prostate
    • Tieva A, Stattin P, Wikström P, Bergh A & Damber JE 2001 Gonadotropin-releasing hormone receptor expression in the human prostate. Prostate 47 276-284.
    • (2001) Prostate , vol.47 , pp. 276-284
    • Tieva, A.1    Stattin, P.2    Wikström, P.3    Bergh, A.4    Damber, J.E.5
  • 108
    • 3843152722 scopus 로고    scopus 로고
    • Gonadotropin releasing hormone-1 expression in incisors of mice
    • Tiong JD, Pakiam JG & Wray S 2004 Gonadotropin releasing hormone-1 expression in incisors of mice. Endocrinology 145 3608-3612.
    • (2004) Endocrinology , vol.145 , pp. 3608-3612
    • Tiong, J.D.1    Pakiam, J.G.2    Wray, S.3
  • 109
    • 33744977637 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone in invertebrates: Structure, function and evolution
    • Tsai PS 2006 Gonadotropin-releasing hormone in invertebrates: structure, function and evolution. General and Comparative Endocrinology 148 48-53.
    • (2006) General and Comparative Endocrinology , vol.148 , pp. 48-53
    • Tsai, P.S.1
  • 112
    • 33846206057 scopus 로고    scopus 로고
    • A processed metabolite of luteinizing hormone-releasing hormone has proliferative effects in endometrial cells
    • 33e1-33e5
    • Walters K, Chin YP & Wu TJ 2007 A processed metabolite of luteinizing hormone-releasing hormone has proliferative effects in endometrial cells. American Journal of Obstetrics and Gynecology 196 33e1-33e5.
    • (2007) American Journal of Obstetrics and Gynecology , vol.196
    • Walters, K.1    Chin, Y.P.2    Wu, T.J.3
  • 114
    • 0022559235 scopus 로고
    • Formation of metabolites of [Arg8] vasopressin (AVP) by brain peptidases. Conversion of the intermediate [Cyt6]AVP-(3-9)
    • Wang XC & Burbach JP 1986 Formation of metabolites of [Arg8] vasopressin (AVP) by brain peptidases. Conversion of the intermediate [Cyt6]AVP-(3-9). FEBS Letters 197 164-168.
    • (1986) FEBS Letters , vol.197 , pp. 164-168
    • Wang, X.C.1    Burbach, J.P.2
  • 116
    • 0027439136 scopus 로고
    • Central nervous system effects of the neurohypophyseal hormones and related peptides
    • de Wied D, Diamant M & Fodor M 1993 Central nervous system effects of the neurohypophyseal hormones and related peptides. Frontiers in Neuroendocrinology 14 251-302.
    • (1993) Frontiers in Neuroendocrinology , vol.14 , pp. 251-302
    • de Wied, D.1    Diamant, M.2    Fodor, M.3
  • 117
    • 33646763494 scopus 로고    scopus 로고
    • Modulation of peripheral inflammation by the substance P N-terminal metabolite substance P1-7
    • Wiktelius D, Khalil Z & Nyberg F 2006 Modulation of peripheral inflammation by the substance P N-terminal metabolite substance P1-7. Peptides 27 1490-1497.
    • (2006) Peptides , vol.27 , pp. 1490-1497
    • Wiktelius, D.1    Khalil, Z.2    Nyberg, F.3
  • 118
    • 0031669970 scopus 로고    scopus 로고
    • Detection of gonadotrophin releasing hormone and its receptor mRNA in human placental trophoblasts using in situ reverse transcription-polymerase chain reaction
    • Wolfahrt S, Kleine B & Rossmanith WG 1998 Detection of gonadotrophin releasing hormone and its receptor mRNA in human placental trophoblasts using in situ reverse transcription-polymerase chain reaction. Molecular Human Reproduction 4 999-1006.
    • (1998) Molecular Human Reproduction , vol.4 , pp. 999-1006
    • Wolfahrt, S.1    Kleine, B.2    Rossmanith, W.G.3
  • 119
    • 0036334307 scopus 로고    scopus 로고
    • Development of gonadotropin-releasing hormone-I neurons
    • Wray S 2002 Development of gonadotropin-releasing hormone-I neurons. Frontiers in Neuroendocrinology 23 292-316.
    • (2002) Frontiers in Neuroendocrinology , vol.23 , pp. 292-316
    • Wray, S.1
  • 121
    • 11144226953 scopus 로고    scopus 로고
    • Stimulation of luteinizing hormone-releasing hormone (LHRH) gene expression in GT1-7 cells by its metabolite, LHRH-(1-5)
    • Wu TJ, Mani SK, Glucksman MJ & Roberts JL 2005 Stimulation of luteinizing hormone-releasing hormone (LHRH) gene expression in GT1-7 cells by its metabolite, LHRH-(1-5). Endocrinology 146 280-286.
    • (2005) Endocrinology , vol.146 , pp. 280-286
    • Wu, T.J.1    Mani, S.K.2    Glucksman, M.J.3    Roberts, J.L.4
  • 122
    • 33645891672 scopus 로고    scopus 로고
    • Facilitation of lordosis in rats by a metabolite of luteinizing hormone releasing hormone
    • Wu TJ, Glucksman MJ, Roberts JL &Mani SK 2006 Facilitation of lordosis in rats by a metabolite of luteinizing hormone releasing hormone. Endocrinology 147 2544-2549.
    • (2006) Endocrinology , vol.147 , pp. 2544-2549
    • Wu, T.J.1    Glucksman, M.J.2    Roberts, J.L.3    Mani, S.K.4
  • 125
    • 0034572335 scopus 로고    scopus 로고
    • Substance P: Transmitter of nociception
    • Zubrzycka M & Janecka A 2000 Substance P: transmitter of nociception. Endocrine Regulations 34 195-201.
    • (2000) Endocrine Regulations , vol.34 , pp. 195-201
    • Zubrzycka, M.1    Janecka, A.2


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