Substance P: Transmitter of nociception (minireview)

Endocrine Regulations

Volumn 34, Issue 4, 2000, Pages 195-201

  Zubrzycka, M ^a   Janecka, A ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

ENKEPHALIN; NEUROPEPTIDE; SUBSTANCE P; TACHYKININ RECEPTOR;

ANIMAL; DRUG ANTAGONISM; EXCITATORY POSTSYNAPTIC POTENTIAL; HUMAN; METABOLISM; NERVE ENDING; PAIN; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW; SPINAL CORD; SYNAPTIC TRANSMISSION;

ANIMALS; ENKEPHALINS; EXCITATORY POSTSYNAPTIC POTENTIALS; HUMANS; NERVE ENDINGS; NEUROPEPTIDES; PAIN; RECEPTORS, TACHYKININ; SPINAL CORD; SUBSTANCE P; SYNAPTIC TRANSMISSION;

EID: 0034572335     PISSN: 12100668     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (57)

1. ATWEH SF, KUCHAR MJ: Autoradiographic localization of opiate receptors in rat brain. I. Spinal cord and lower medulla. Brain Res 124, 53-67, 1977
2. CAMERON AA, LEAH JD, SNOW PJ: The coexistence of neuropeptides in feline sensory neurons. Neuroscience 27, 969-979, 1988
3. DUGGAN AW, HOPE PJ, JARROTT B, SCHAIBLE HG, FLEETWOOD-WALKER SM: Release, spread and persistence of immunoreactive neurokinin A in the dorsal horn of the cat following noxious cutaneous stimulation. Studies with antibody microprobes. Neuroscience 35, 195-202, 1990
4. FREDERICKSON RCA, BURGIS V, HARRELL CE, EDWARDS JD: Dual actions of substance P on nociception: Possible role of endogenous opioids. Science 199, 1359-1362, 1978
5. FURST S: Transmitters involved in antinociception in the spinal cord. Brain Res Bull 48, 129-141, 1999
6. HELKE CJ, CHARLTON CG, WILEY RG: Studies on the cellular localisation of spinal cord substance P receptors. Neuroscience 19, 523-533, 1986
7. HENRY JL: Effects of substance P on functionally identified units in cat spinal cord. Brain Res 114, 439-451, 1976
8. HOEKFELT T, KELLERTH JO, NILSSON G, PERNOW B: Experimental immunohistochemical studies on the localization and distribution of substance P in cat primary sensory neurons. Brain Res 100, 235-252, 1975
9. HYLDEN JKL, WILCOX GL: Intrathecal substance P elicits a caudally-directed biting and scrathing behavior in mice. Brain Res 217, 212-215, 1981
10. IVERSEN LL: Substance P. Brit Med Bull 38, 277-282, 1982
11. JESSELL T, TSUNOO A, KANAZAWAA I, OTSUKA M: Substance P depletion: in the dorsal horn of rat spinal cord after section of the peripheral processes of primary sensory neurons. Brain Res 168, 247-259, 1979
12. KONISHI S, OTSUKA M: Excitatory action of hypothalamic substance P on spinal motoneurones of newborn rats. Nature (Lond) 252, 734-735, 1974
13. KONISHI S, OTSUKA M: Blockade of slow excitatory post-synaptic potential by substance P antagonists in guinea-pig sympathetic ganglia. J Physiol (Lond) 361, 115-130, 1985
14. KONISHI SA., TSUNOO A, YANAIHARA N, OTSUKA M: Peptidergic excitatory and inhibitory synapses in mammalian sympathetic ganglia: roles of substance P and enkephalin. Biomed Res 1, 528-536 1980
15. KURAISHI Y, SATOH M: Neuropeptides as transmitter of biowarning system. Neurose Res 11, Suppl 3, 1990
16. LAMOTTE CC, SHAPIRO CM: Ultrastructural localization of substance P, met-enkephalin, and somatostatin immunoreactivity in lamina X of the primate spinal cord. J Comp Neural 306, 290-306, 1991.
17. LEMBECK F, FOLKERS K, DONNERER J: Analgesic effect of antagonists of substance P. Biochem Biophys Res . Commun 103, 1318-1321, 1981
18. LJUNGDAHL A, HOEKFELT T, NILSSON G: Distribution of substance P-like immunoreactivity in the central nervous system of the rat. I. Cell bodies and nerve terminals. Neuroscience 3, 861-943, 1978
19. LYNN B, HUNT SP: Afferent C-fibres physiological and biochemical correlations. Trends Neurosci 7, 186-188, 1984
20. MA W, RIBEIRO-DA-SILVA A, DE-KONNICK Y RADHAKRISHNAN V CUELLO AC, HENRY JL: Substance P and enkephalin immunoreactivities in axonal boutons presynaptic to physiologically identified dorsal hom neurons. An ultrastructural multiple-labelling study in the cat. Neuroscience 77, 793-811, 1997
21. MCCARSON KE: Central and peripheral expression of neurokinin-1 and neurokinin-3 receptor and substance P-encoding messenger RNAs: peripheral regulation during formalin-induced inflamation and lack of neurokinin receptor expression in primary afferent sensory neurons. Neuroscience 93, 361-370, 1999
22. MANTYH PW, GATES T, MANTYCH CR, MAGGIO JE: Autoradiographic localization and characterization of tachykinin receptor binding sites in the rat brain and peripheral tissues. J Neurosci 9, 258-279, 1989
23. MARTIN-SCHILD S, GERALL AA, KASTIN AJ, ZADINA JE: Endomorphin-2 is an endogenous opioid in primary sensory afferent fibers. Peptides 19, 1783-1789, 1998
24. MERIGHI A, POLAK JM, THEODOSIS DT: Ultrastructural visualization of glutamate and aspartate immunoreactivites in the rat dorsal horn, with special reference to the co-localization of glutamate, substance P and calcitonin-gene releated peptide. Neuroscience 40, 67-80, 1991
25. MIYATA Y, OTSUKA M: Quantitative histochemistry of gamma-aminobutyric acid in cat spinal cord with special reference to presynaptic inhibition. J Neurochem 25, 239-244, 1975
26. MORTON CR, HUTCHISON WD, HENDRY IA: Release of immunoreactive somatostatin in the spinal dorsal horn of the cat. Neuropeptides 12, 189-197, 1988
27. MORTON CR, HUTCHISON WD: Release of sensory neuropeptides in the spinal cord: studies with calcitonin generelated peptlde and galanin. Neuroscience 31, 807-815, 1989
28. NAGY JI, HUNT SP, IVERSEN LL, EMSON PC: Biochemical and anatomical observations on the degeneration of peptide-containing primary afferent neurons after neonatal capsaicin. Neuroscience 6, 1923-1934, 1981
29. NAGY JI, VAN DER KOOY D: Effects on neonatal capsaicin treatment on nociceptive thresholds in the rat. J Neurosci 3, 1145-1150, 1983
30. NARITA M, TSENG LF: Evidence for the existence of the beta-endorphin-sensitive 'epsilon-opioid receptor' in the brain: the mechanisms of epsilon-mediated antinociception. Jpn J Pharmacol 76, 233-253, 1998
31. NEWTON BW, HAMILL RW: Target regulation of the serotonin and substance P innervation of the sexually dimorphic cremaster nucleus. Brain Res 485, 149-156, 1989
32. NINKOVIC M, BEAUJOUAN JC, TORRENS Y, SAFFROY M, HALL MD, GLOWINSKI J: Diferential localization of tachykinin receptors in rat spinal cord. Eur J Pharmacol 106, 463-464, 1984
33. NOWAK L, MACDONALD RL: Substance P: ionic basis for depolarizing responses of mouse spinal cord neurns in cell culture. J Neurosci 2, 1119-1128, 1982
34. OEHME P, HILSE H, MORGENSTERN E, GORES E: Substance P does it produce analgesia or hyperalgesia?. Science 208, 305-307, 1980
35. OKU R, SATOH M, FUJII N, OTAKA A, YAJIMA H, TAKAGI H: Calcitonin gene-releated peptide promotes mechanical nociception by potentiating release of substance P from the spinal dorsal horn in rats. Brain Res 403, 350-354, 1987
36. OTSUKA M, KONISHI S: Release of substance P-like immunoreactivity from isolated spinal cord of newborn rat. Nature (Lond) 264, 83-84, 1976
37. OTSUKA M, YANAGISAWA M: The effects of substance P and baclofen on motoneurones of isolated spinal cord of the newborn rat. J Exp Biol 89, 201-214, 1980
38. OTSUKA M, YANAGISAWA M: Does substance P act as a pain transmitter?. Trends Phannacol Sci 8, 506-510, 1987
39. PIORO EP, HUGHES JT, CUELLO AC: Demonstration of substance P immunoreactivity in the nucleus dorsalis of human spinal cord. Neurosci Lett 51, 61-65, 1984
40. POLLARD H, BOUTHENET ML, MOREAU J, SOUIL E, VERROUST P, RONCO P, SCHWARTZ JC: Detailed immunoautoradiographic mapping of enkephalinase (EC 3.4.24.11) in rat central nervous system: comparison with enkephalins and substance P. Neuroscience 30, 339-376, 1989
41. REN J, HU HZ, LIU S, XIA Y, WOOD JD: Glutamate modulates neurotransmission in the submucosal plexus of guinea-pig small intestine. Neuroreport 10, 3045-3048, 1999
42. SELLEY ED, BIDLACK JM: Effect of ß-endorphin on mu and d opioid receptor-coupled G-protein activity: low-Km GTP-ase studies. J Pharmacol Exp Ther 263, 99-104, 1992
43. STAPELFELDT WH, SZURSZEWSKI JH: Neurotensin facilitates release of substance P in the guinea-pig inferior mesenteric ganglion. J Physiol (Lond) 411, 325-345, 1989
44. STEWART JM, GRETTO CJ, NELDNER K, REEV EB, KRIVOY W, ZIMMERMANN M: Substance P and analgesia. Nature (Lond) 262, 784-785, 1976
45. STROES JW, BAST A: Functional receptors and binding sites for tachykinins. Trends Pharmacol Sci 7, 302, 1986
46. TAKAHASHI T, OTSUKA M: Regional distribution of substance P in the spinal cord and nerve roots of the cat and the effect of dorsal root section. Brain Res 87, 1-11, 1975
47. TRAFTON JA, ABBADIE C, MARCHAND S, MANTYCH PW, BASABAUM AI: Spinal opioid analgesia: how critical is the regulation of substance P signaling?. J Neurosci 19, 9642-9653, 1999
48. TSUCHIDA K, SHIGEMOTO R, YOKOTA Y, NAKANISHI S: Tissue distribution and quantitation of the mRNAs for three rat tachykinin receptors. Eur J Biochem 193, 751-757, 1990
49. TSUNOO A, KONISHI S, OTSUKA M: Substance P as an excitatory transmitter of primary afferent neurons in guinea-pig sympathetic ganglia. Neuroscience 7, 2025-2037, 1982
50. URBAN L, RANDIC M: Slow excitatory transmission in rat dorsal hom: possible mediation by peptides. Brain Res 290, 336-341, 1984
51. WIESENFELD-HALLIN Z: Substance P and somatostatin modulate spinal cord excitability via physiologically different sensory pathways. Brain Res 6, 172-175, 1986
52. WOOLF C, WIESENFELD-HALLIN Z: Substance P and calcitonin gene-releated peptide synergistically modulate the gain of the nociceptive flexor withdrawal reflex in the rat. Neurosci Lett 66, 226-230, 1986
53. YANAGISAWA M, OTSUKA M: Pharmacological profile of a tachykinin antagonist, spantide, as examined on rat spinal motoneurones. Br J Pharmacol 100, 711-716, 1990
54. YANAGISAWA M, YAGI N, OTSUKA M, YANAIHARA C, YANAIHARA N: Inhibitory effects of galanin on the isolated spinal cord of the newborn rat. Neurosci Lett 70, 278-282, 1986
55. YASHPAL K, HENRY JL: Endorphins mediate overshoot of substance P-induced facilitation of a spinal nociceptive reflex. Can J Physiol Pharmacol 61, 303-307, 1983
56. ZUBRZYCKA M, JANECKA A, KOZIOLKIEWICZ W, TRACZYK WZ: Inhibition of tongue reflex in rats by tooth pulp stimulation during cerebral ventricle perfusion with (6-11) substance P analogs. Brain Res 753, 128-132, 1997
57. ZUBRZYCKA M, JANECKA A, TRACZYK WZ: Comparison of antagonistic properties of substance P analpgs, spantide I, II and III on evoked tongue jerks in rats. Endocrine Regul 34, 13-18, 2000