-
1
-
-
35448961665
-
When cilia go bad: cilia defects and ciliopathies
-
Fliegauf, M., Benzing, T. and Omran, H. (2007) When cilia go bad: cilia defects and ciliopathies. Nat. Rev. Mol. Cell Biol. 8, 880-893.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 880-893
-
-
Fliegauf, M.1
Benzing, T.2
Omran, H.3
-
2
-
-
5744244393
-
Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation
-
Ibanez-Tallon, I., Pagenstecher, A., Fliegauf, M., Olbrich, H., Kispert, A., Ketelsen, U.P. et al. (2004) Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation. Hum. Mol. Genet. 13, 2133-2141.
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 2133-2141
-
-
Ibanez-Tallon, I.1
Pagenstecher, A.2
Fliegauf, M.3
Olbrich, H.4
Kispert, A.5
Ketelsen, U.P.6
-
3
-
-
0034677929
-
The dynein microtubule motor
-
King, S.M. (2000) The dynein microtubule motor. Biochim. Biophys. Acta 1496, 60-75.
-
(2000)
Biochim. Biophys. Acta
, vol.1496
, pp. 60-75
-
-
King, S.M.1
-
4
-
-
20944436797
-
The ciliary rootlet maintains long-term stability of sensory cilia
-
Yang, J., Gao, J., Adamian, M., Wen, X.H., Pawlyk, B., Zhang, L. et al. (2005) The ciliary rootlet maintains long-term stability of sensory cilia. Mol. Cell Biol. 25, 4129-4137.
-
(2005)
Mol. Cell Biol.
, vol.25
, pp. 4129-4137
-
-
Yang, J.1
Gao, J.2
Adamian, M.3
Wen, X.H.4
Pawlyk, B.5
Zhang, L.6
-
5
-
-
18744406718
-
FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination
-
Tanaka, Y., Okada, Y. and Hirokawa, N. (2005) FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination. Nature 435, 172-177.
-
(2005)
Nature
, vol.435
, pp. 172-177
-
-
Tanaka, Y.1
Okada, Y.2
Hirokawa, N.3
-
6
-
-
0033212985
-
Abnormal nodal flow precedes situs inversus in iv and inv mice
-
Okada, Y., Nonaka, S., Tanaka, Y., Saijoh, Y., Hamada, H. and Hirokawa, N. (1999) Abnormal nodal flow precedes situs inversus in iv and inv mice. Mol. Cell 4, 459-468.
-
(1999)
Mol. Cell
, vol.4
, pp. 459-468
-
-
Okada, Y.1
Nonaka, S.2
Tanaka, Y.3
Saijoh, Y.4
Hamada, H.5
Hirokawa, N.6
-
7
-
-
18844393668
-
Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis
-
Kramer-Zucker, A.G., Olale, F., Haycraft, C.J., Yoder, B.K., Schier, A.F. and Drummond, I.A. (2005) Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis. Development 132, 1907-1921.
-
(2005)
Development
, vol.132
, pp. 1907-1921
-
-
Kramer-Zucker, A.G.1
Olale, F.2
Haycraft, C.J.3
Yoder, B.K.4
Schier, A.F.5
Drummond, I.A.6
-
8
-
-
63049116544
-
The vertebrate primary cilium in development, homeostasis, and disease
-
Gerdes, J.M., Davis, E.E. and Katsanis, N. (2009) The vertebrate primary cilium in development, homeostasis, and disease. Cell 137, 32-45.
-
(2009)
Cell
, vol.137
, pp. 32-45
-
-
Gerdes, J.M.1
Davis, E.E.2
Katsanis, N.3
-
9
-
-
0037317302
-
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
-
Nauli, S.M., Alenghat, F.J., Luo, Y., Williams, E., Vassilev, P., Li, X. et al. (2003) Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells. Nat. Genet. 33, 129-137.
-
(2003)
Nat. Genet.
, vol.33
, pp. 129-137
-
-
Nauli, S.M.1
Alenghat, F.J.2
Luo, Y.3
Williams, E.4
Vassilev, P.5
Li, X.6
-
10
-
-
0035498717
-
Bending the MDCK cell primary cilium increases intracellular calcium
-
Praetorius, H.A. and Spring, K.R. (2001) Bending the MDCK cell primary cilium increases intracellular calcium. J. Membr. Biol. 184, 71-79.
-
(2001)
J. Membr. Biol.
, vol.184
, pp. 71-79
-
-
Praetorius, H.A.1
Spring, K.R.2
-
11
-
-
0242581681
-
Hedgehog signalling in the mouse requires intraflagellar transport proteins
-
Huangfu, D., Liu, A., Rakeman, A.S., Murcia, N.S., Niswander, L. and Anderson, K.V. (2003) Hedgehog signalling in the mouse requires intraflagellar transport proteins. Nature 426, 83-87.
-
(2003)
Nature
, vol.426
, pp. 83-87
-
-
Huangfu, D.1
Liu, A.2
Rakeman, A.S.3
Murcia, N.S.4
Niswander, L.5
Anderson, K.V.6
-
12
-
-
27744484694
-
Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli
-
May, S.R., Ashique, A.M., Karlen, M., Wang, B., Shen, Y., Zarbalis, K. et al. (2005) Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli. Dev. Biol. 287, 378-389.
-
(2005)
Dev. Biol.
, vol.287
, pp. 378-389
-
-
May, S.R.1
Ashique, A.M.2
Karlen, M.3
Wang, B.4
Shen, Y.5
Zarbalis, K.6
-
13
-
-
40849142136
-
Human embryonic stem cells in culture possess primary cilia with hedgehog signaling machinery
-
Kiprilov, E.N., Awan, A., Desprat, R., Velho, M., Clement, C.A., Byskov, A.G. et al. (2008) Human embryonic stem cells in culture possess primary cilia with hedgehog signaling machinery. J. Cell Biol. 180, 897-904.
-
(2008)
J. Cell Biol.
, vol.180
, pp. 897-904
-
-
Kiprilov, E.N.1
Awan, A.2
Desprat, R.3
Velho, M.4
Clement, C.A.5
Byskov, A.G.6
-
14
-
-
20944435539
-
Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways
-
Simons, M., Gloy, J., Ganner, A., Bullerkotte, A., Bashkurov, M., Kronig, C. et al. (2005) Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways. Nat. Genet. 37, 537-543.
-
(2005)
Nat. Genet.
, vol.37
, pp. 537-543
-
-
Simons, M.1
Gloy, J.2
Ganner, A.3
Bullerkotte, A.4
Bashkurov, M.5
Kronig, C.6
-
15
-
-
25144504913
-
Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway
-
Wang, J., Mark, S., Zhang, X., Qian, D., Yoo, S.J., Radde-Gallwitz, K. et al. (2005) Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway. Nat. Genet. 37, 980-985.
-
(2005)
Nat. Genet.
, vol.37
, pp. 980-985
-
-
Wang, J.1
Mark, S.2
Zhang, X.3
Qian, D.4
Yoo, S.J.5
Radde-Gallwitz, K.6
-
16
-
-
0029050218
-
The kinocilium of auditory hair cells and evidence for its morphogenetic role during the regeneration of stereocilia and cuticular plates
-
Sobkowicz, H.M., Slapnick, S.M. and August, B.K. (1995) The kinocilium of auditory hair cells and evidence for its morphogenetic role during the regeneration of stereocilia and cuticular plates. J. Neurocytol. 24, 633-653.
-
(1995)
J. Neurocytol.
, vol.24
, pp. 633-653
-
-
Sobkowicz, H.M.1
Slapnick, S.M.2
August, B.K.3
-
17
-
-
33845354764
-
Three types of cilia including a novel 9+4 axoneme on the notochordal plate of the rabbit embryo
-
Feistel, K. and Blum, M. (2006) Three types of cilia including a novel 9+4 axoneme on the notochordal plate of the rabbit embryo. Dev. Dyn. 235, 3348- 3358.
-
(2006)
Dev. Dyn.
, vol.235
, pp. 3348-3358
-
-
Feistel, K.1
Blum, M.2
-
18
-
-
2442631432
-
Genetic disorders of cilia
-
(ed. Schweiger, H.G.), Springer-Verlag, Berlin
-
Afzelius, B.A. (1980) Genetic disorders of cilia. In International Cell Biology 1980-1981 (ed. Schweiger, H.G.), Springer-Verlag, Berlin, p. 8.
-
(1980)
International Cell Biology 1980-1981
, pp. 8
-
-
Afzelius, B.A.1
-
19
-
-
7944223873
-
Cilia-related diseases
-
Afzelius, B.A. (2004) Cilia-related diseases. J. Pathol. 204, 470-477.
-
(2004)
J. Pathol.
, vol.204
, pp. 470-477
-
-
Afzelius, B.A.1
-
20
-
-
0031753833
-
Primary ciliary dyskinesia: diagnosis and standards of care
-
Bush, A., Cole, P., Hariri, M., Mackay, I., Phillips, G., O'Callaghan, C. et al. (1998) Primary ciliary dyskinesia: diagnosis and standards of care. Eur. Respir. J. 12, 982-988.
-
(1998)
Eur. Respir. J.
, vol.12
, pp. 982-988
-
-
Bush, A.1
Cole, P.2
Hariri, M.3
Mackay, I.4
Phillips, G.5
O'Callaghan, C.6
-
21
-
-
39049093347
-
Mutations in Hydin impair ciliary motility in mice
-
Lechtreck, K.F., Delmotte, P., Robinson, M.L., Sanderson, M.J. and Witman, G.B. (2008) Mutations in Hydin impair ciliary motility in mice. J. Cell Biol. 180, 633-643.
-
(2008)
J. Cell Biol.
, vol.180
, pp. 633-643
-
-
Lechtreck, K.F.1
Delmotte, P.2
Robinson, M.L.3
Sanderson, M.J.4
Witman, G.B.5
-
22
-
-
33748769378
-
The ciliopathies: an emerging class of human genetic disorders
-
Badano, J.L., Mitsuma, N., Beales, P.L. and Katsanis, N. (2006) The ciliopathies: an emerging class of human genetic disorders. Annu. Rev. Genomics Hum. Genet. 7, 125-148.
-
(2006)
Annu. Rev. Genomics Hum. Genet.
, vol.7
, pp. 125-148
-
-
Badano, J.L.1
Mitsuma, N.2
Beales, P.L.3
Katsanis, N.4
-
23
-
-
0037087624
-
Loss of function of axonemal dynein Mdnah5 causes primary ciliary dyskinesia and hydrocephalus
-
Ibanez-Tallon, I., Gorokhova, S. and Heintz, N. (2002) Loss of function of axonemal dynein Mdnah5 causes primary ciliary dyskinesia and hydrocephalus. Hum. Mol. Genet. 11, 715-721.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 715-721
-
-
Ibanez-Tallon, I.1
Gorokhova, S.2
Heintz, N.3
-
24
-
-
0027772235
-
Immotile cilia syndrome associated with hydrocephalus and precocious puberty: a case report
-
Picco, P., Leveratto, L., Cama, A., Vigliarolo, M.A., Levato, G.L., Gattorno, M. et al. (1993) Immotile cilia syndrome associated with hydrocephalus and precocious puberty: a case report. Eur. J. Pediatr. Surg. 3 (Suppl. 1), 20-21.
-
(1993)
Eur. J. Pediatr. Surg.
, vol.3
, Issue.SUPPL. 1
, pp. 20-21
-
-
Picco, P.1
Leveratto, L.2
Cama, A.3
Vigliarolo, M.A.4
Levato, G.L.5
Gattorno, M.6
-
25
-
-
33646204913
-
Nodal flow and the generation of left-right asymmetry
-
Hirokawa, N., Tanaka, Y., Okada, Y. and Takeda, S. (2006) Nodal flow and the generation of left-right asymmetry. Cell 125, 33-45.
-
(2006)
Cell
, vol.125
, pp. 33-45
-
-
Hirokawa, N.1
Tanaka, Y.2
Okada, Y.3
Takeda, S.4
-
26
-
-
0037019287
-
Determination of left-right patterning of the mouse embryo by artificial nodal flow
-
Nonaka, S., Shiratori, H., Saijoh, Y. and Hamada, H. (2002) Determination of left-right patterning of the mouse embryo by artificial nodal flow. Nature 418, 96-99.
-
(2002)
Nature
, vol.418
, pp. 96-99
-
-
Nonaka, S.1
Shiratori, H.2
Saijoh, Y.3
Hamada, H.4
-
27
-
-
0032428685
-
Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein
-
Nonaka, S., Tanaka, Y., Okada, Y., Takeda, S., Harada, A., Kanai, Y. et al. (1998) Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein. Cell 95, 829-837.
-
(1998)
Cell
, vol.95
, pp. 829-837
-
-
Nonaka, S.1
Tanaka, Y.2
Okada, Y.3
Takeda, S.4
Harada, A.5
Kanai, Y.6
-
28
-
-
23944510234
-
De novo formation of left-right asymmetry by posterior tilt of nodal cilia
-
Nonaka, S., Yoshiba, S., Watanabe, D., Ikeuchi, S., Goto, T., Marshall, W.F. et al. (2005) De novo formation of left-right asymmetry by posterior tilt of nodal cilia. PLoS Biol. 3, e268.
-
(2005)
PLoS Biol
, vol.3
-
-
Nonaka, S.1
Yoshiba, S.2
Watanabe, D.3
Ikeuchi, S.4
Goto, T.5
Marshall, W.F.6
-
29
-
-
19344367605
-
Mechanism of nodal flow: a conserved symmetry breaking event in left-right axis determination
-
Okada, Y., Takeda, S., Tanaka, Y., Belmonte, J.C. and Hirokawa, N. (2005) Mechanism of nodal flow: a conserved symmetry breaking event in left-right axis determination. Cell 121, 633-644.
-
(2005)
Cell
, vol.121
, pp. 633-644
-
-
Okada, Y.1
Takeda, S.2
Tanaka, Y.3
Belmonte, J.C.4
Hirokawa, N.5
-
30
-
-
0017162819
-
A human syndrome caused by immotile cilia
-
Afzelius, B.A. (1976) A human syndrome caused by immotile cilia. Science 193, 317-319.
-
(1976)
Science
, vol.193
, pp. 317-319
-
-
Afzelius, B.A.1
-
31
-
-
33846396811
-
Frizzled/PCP signalling: a conserved mechanism regulating cell polarity and directed motility
-
Seifert, J.R. and Mlodzik, M. (2007) Frizzled/PCP signalling: a conserved mechanism regulating cell polarity and directed motility. Nat. Rev. Genet. 8, 126-138.
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 126-138
-
-
Seifert, J.R.1
Mlodzik, M.2
-
32
-
-
33646941288
-
Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals
-
Montcouquiol, M., Sans, N., Huss, D., Kach, J., Dickman, J.D., Forge, A. et al. (2006) Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals. J. Neurosci. 26, 5265-5275.
-
(2006)
J. Neurosci.
, vol.26
, pp. 5265-5275
-
-
Montcouquiol, M.1
Sans, N.2
Huss, D.3
Kach, J.4
Dickman, J.D.5
Forge, A.6
-
33
-
-
44649101853
-
Asymmetric homotypic interactions of the atypical cadherin flamingo mediate intercellular polarity signaling
-
Chen, W.S., Antic, D., Matis, M., Logan, C.Y., Povelones, M., Anderson, G.A. et al. (2008) Asymmetric homotypic interactions of the atypical cadherin flamingo mediate intercellular polarity signaling. Cell 133, 1093-1105.
-
(2008)
Cell
, vol.133
, pp. 1093-1105
-
-
Chen, W.S.1
Antic, D.2
Matis, M.3
Logan, C.Y.4
Povelones, M.5
Anderson, G.A.6
-
34
-
-
33749018196
-
Planar cell polarity, ciliogenesis and neural tube defects
-
Wallingford, J.B. (2006) Planar cell polarity, ciliogenesis and neural tube defects. Hum. Mol. Genet. 15 (2), R227-R234.
-
(2006)
Hum. Mol. Genet.
, vol.15
, Issue.2
-
-
Wallingford, J.B.1
-
35
-
-
0025770285
-
Auditory epithelial migration. III. Development of the stratified squamous epithelium of the tympanic membrane and external canal in the mouse
-
Michaels, L. and Soucek, S. (1991) Auditory epithelial migration. III. Development of the stratified squamous epithelium of the tympanic membrane and external canal in the mouse. Am. J. Anat. 191, 280-292.
-
(1991)
Am. J. Anat.
, vol.191
, pp. 280-292
-
-
Michaels, L.1
Soucek, S.2
-
36
-
-
30544439006
-
Planar cell polarity signalling couples cell division and morphogenesis during neurulation
-
Ciruna, B., Jenny, A., Lee, D., Mlodzik, M. and Schier, A.F. (2006) Planar cell polarity signalling couples cell division and morphogenesis during neurulation. Nature 439, 220-224.
-
(2006)
Nature
, vol.439
, pp. 220-224
-
-
Ciruna, B.1
Jenny, A.2
Lee, D.3
Mlodzik, M.4
Schier, A.F.5
-
37
-
-
37549052499
-
Ciliary proteins link basal body polarization to planar cell polarity regulation
-
Jones, C., Roper, V.C., Foucher, I., Qian, D., Banizs, B., Petit, C. et al. (2008) Ciliary proteins link basal body polarization to planar cell polarity regulation. Nat. Genet. 40, 69-77.
-
(2008)
Nat. Genet.
, vol.40
, pp. 69-77
-
-
Jones, C.1
Roper, V.C.2
Foucher, I.3
Qian, D.4
Banizs, B.5
Petit, C.6
-
38
-
-
27144460671
-
Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates
-
Ross, A.J., May-Simera, H., Eichers, E.R., Kai, M., Hill, J., Jagger, D.J. et al. (2005) Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates. Nat. Genet. 37, 1135-1140.
-
(2005)
Nat. Genet.
, vol.37
, pp. 1135-1140
-
-
Ross, A.J.1
May-Simera, H.2
Eichers, E.R.3
Kai, M.4
Hill, J.5
Jagger, D.J.6
-
39
-
-
4744352094
-
Van Goghlike2 (Strabismus) and its role in planar cell polarity and convergent extension in vertebrates
-
Torban, E., Kor, C. and Gros, P. (2004) Van Goghlike2 (Strabismus) and its role in planar cell polarity and convergent extension in vertebrates. Trends Genet. 20, 570-577.
-
(2004)
Trends Genet
, vol.20
, pp. 570-577
-
-
Torban, E.1
Kor, C.2
Gros, P.3
-
40
-
-
55549083477
-
Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles
-
Devenport, D. and Fuchs, E. (2008) Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles. Nat. Cell Biol. 10, 1257-1268.
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 1257-1268
-
-
Devenport, D.1
Fuchs, E.2
-
41
-
-
3042694211
-
Frizzled6 controls hair patterning in mice
-
Guo, N., Hawkins, C. and Nathans, J. (2004) Frizzled6 controls hair patterning in mice. Proc. Natl. Acad. Sci. USA 101, 9277-9281.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 9277-9281
-
-
Guo, N.1
Hawkins, C.2
Nathans, J.3
-
42
-
-
46249125254
-
Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells
-
Park, T.J., Mitchell, B.J., Abitua, P.B., Kintner, C. and Wallingford, J.B. (2008) Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells. Nat. Genet. 40, 871-879.
-
(2008)
Nat. Genet.
, vol.40
, pp. 871-879
-
-
Park, T.J.1
Mitchell, B.J.2
Abitua, P.B.3
Kintner, C.4
Wallingford, J.B.5
-
43
-
-
39149087667
-
Cilia orientation and the fluid mechanics of development
-
Marshall, W.F. and Kintner, C. (2008) Cilia orientation and the fluid mechanics of development. Curr. Opin. Cell Biol. 20, 48-52.
-
(2008)
Curr. Opin. Cell Biol.
, vol.20
, pp. 48-52
-
-
Marshall, W.F.1
Kintner, C.2
-
44
-
-
34247555530
-
A positive feedback mechanism governs the polarity and motion of motile cilia
-
Mitchell, B., Jacobs, R., Li, J., Chien, S. and Kintner, C. (2007) A positive feedback mechanism governs the polarity and motion of motile cilia. Nature 447, 97-101.
-
(2007)
Nature
, vol.447
, pp. 97-101
-
-
Mitchell, B.1
Jacobs, R.2
Li, J.3
Chien, S.4
Kintner, C.5
-
45
-
-
65549170297
-
Fused has evolved divergent roles in vertebrate Hedgehog signalling and motile ciliogenesis
-
Wilson, C.W., Nguyen, C.T., Chen, M.H., Yang, J.H., Gacayan, R., Huang, J. et al. (2009) Fused has evolved divergent roles in vertebrate Hedgehog signalling and motile ciliogenesis. Nature 459, 98-102.
-
(2009)
Nature
, vol.459
, pp. 98-102
-
-
Wilson, C.W.1
Nguyen, C.T.2
Chen, M.H.3
Yang, J.H.4
Gacayan, R.5
Huang, J.6
-
46
-
-
0013784893
-
Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats
-
Altman, J. and Das, G.D. (1965) Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats. J. Comp. Neurol. 124, 319-335.
-
(1965)
J. Comp. Neurol.
, vol.124
, pp. 319-335
-
-
Altman, J.1
Das, G.D.2
-
47
-
-
58549112780
-
Identity crisis for adult periventricular neural stem cells: subventricular zone astrocytes, ependymal cells or both?
-
Chojnacki, A.K., Mak, G.K. and Weiss, S. (2009) Identity crisis for adult periventricular neural stem cells: subventricular zone astrocytes, ependymal cells or both? Nat. Rev. Neurosci. 10, 153-163.
-
(2009)
Nat. Rev. Neurosci.
, vol.10
, pp. 153-163
-
-
Chojnacki, A.K.1
Mak, G.K.2
Weiss, S.3
-
48
-
-
33846524307
-
Neuronal migration in the adult brain: are we there yet?
-
Ghashghaei, H.T., Lai, C. and Anton, E.S. (2007) Neuronal migration in the adult brain: are we there yet? Nat. Rev. Neurosci. 8, 141-151.
-
(2007)
Nat. Rev. Neurosci.
, vol.8
, pp. 141-151
-
-
Ghashghaei, H.T.1
Lai, C.2
Anton, E.S.3
-
49
-
-
31944434903
-
New neurons follow the flow of cerebrospinal uid in the adult brain
-
Sawamoto, K., Wichterle, H., Gonzalez-Perez, O., Cholfin, J.A., Yamada, M., Spassky, N. et al. (2006) New neurons follow the flow of cerebrospinal uid in the adult brain. Science 311, 629-632.
-
(2006)
Science
, vol.311
, pp. 629-632
-
-
Sawamoto, K.1
Wichterle, H.2
Gonzalez-Perez, O.3
Cholfin, J.A.4
Yamada, M.5
Spassky, N.6
-
50
-
-
12144262775
-
Adult ependymal cells are postmitotic and are derived from radial glial cells during embryogenesis
-
Spassky, N., Merkle, F.T., Flames, N., Tramontin, A.D., Garcia-Verdugo, J.M. and Alvarez-Buylla, A. (2005) Adult ependymal cells are postmitotic and are derived from radial glial cells during embryogenesis. J. Neurosci. 25, 10-18.
-
(2005)
J. Neurosci.
, vol.25
, pp. 10-18
-
-
Spassky, N.1
Merkle, F.T.2
Flames, N.3
Tramontin, A.D.4
Garcia-Verdugo, J.M.5
Alvarez-Buylla, A.6
-
51
-
-
60749099023
-
Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after stroke
-
Carlen, M., Meletis, K., Goritz, C., Darsalia, V., Evergren, E., Tanigaki, K. et al. (2009) Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after stroke. Nat. Neurosci. 12, 259-267.
-
(2009)
Nat. Neurosci.
, vol.12
, pp. 259-267
-
-
Carlen, M.1
Meletis, K.2
Goritz, C.3
Darsalia, V.4
Evergren, E.5
Tanigaki, K.6
-
52
-
-
70449646115
-
The dynamic cilium in human diseases
-
D'Angelo, A. and Franco, B. (2009) The dynamic cilium in human diseases. Pathogenetics 2, 3.
-
(2009)
Pathogenetics
, vol.2
, pp. 3
-
-
D'Angelo, A.1
Franco, B.2
-
53
-
-
38349018369
-
The cell biological basis of ciliary disease
-
Marshall, W.F. (2008) The cell biological basis of ciliary disease. J. Cell Biol. 180, 17-21.
-
(2008)
J. Cell Biol.
, vol.180
, pp. 17-21
-
-
Marshall, W.F.1
-
54
-
-
0036578890
-
Mutations in ALMS1 cause obesity, type 2 diabetes and neurosensory degeneration in Alstrom syndrome
-
Collin, G.B., Marshall, J.D., Ikeda, A., So, W.V., Russell-Eggitt, I., Maffei, P. et al. (2002) Mutations in ALMS1 cause obesity, type 2 diabetes and neurosensory degeneration in Alstrom syndrome. Nat. Genet. 31, 74-78.
-
(2002)
Nat. Genet.
, vol.31
, pp. 74-78
-
-
Collin, G.B.1
Marshall, J.D.2
Ikeda, A.3
So, W.V.4
Russell-Eggitt, I.5
Maffei, P.6
-
55
-
-
18544391142
-
Mutation of ALMS1, a large gene with a tandem repeat encoding 47 amino acids, causes Alstrom syndrome
-
Hearn, T., Renforth, G.L., Spalluto, C., Hanley, N.A., Piper, K., Brickwood, S. et al. (2002) Mutation of ALMS1, a large gene with a tandem repeat encoding 47 amino acids, causes Alstrom syndrome. Nat. Genet. 31, 79-83.
-
(2002)
Nat. Genet.
, vol.31
, pp. 79-83
-
-
Hearn, T.1
Renforth, G.L.2
Spalluto, C.3
Hanley, N.A.4
Piper, K.5
Brickwood, S.6
-
56
-
-
35348816684
-
Mutation analysis of NPHP6/CEP290 in patients with Joubert syndrome and Senior-Loken syndrome
-
Helou, J., Otto, E.A., Attanasio, M., Allen, S.J., Parisi, M.A., Glass, I. et al. (2007) Mutation analysis of NPHP6/CEP290 in patients with Joubert syndrome and Senior-Loken syndrome. J. Med. Genet. 44, 657-663.
-
(2007)
J. Med. Genet.
, vol.44
, pp. 657-663
-
-
Helou, J.1
Otto, E.A.2
Attanasio, M.3
Allen, S.J.4
Parisi, M.A.5
Glass, I.6
-
57
-
-
20144375842
-
Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin
-
Otto, E.A., Loeys, B., Khanna, H., Hellemans, J., Sudbrak, R., Fan, S. et al. (2005) Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin. Nat. Genet. 37, 282-288.
-
(2005)
Nat. Genet.
, vol.37
, pp. 282-288
-
-
Otto, E.A.1
Loeys, B.2
Khanna, H.3
Hellemans, J.4
Sudbrak, R.5
Fan, S.6
-
58
-
-
0036842902
-
A gene mutated in nephronophthisis and retinitis pigmentosa encodes a novel protein, nephroretinin, conserved in evolution
-
Otto, E., Hoefele, J., Ruf, R., Mueller, A.M., Hiller, K.S., Wolf, M.T. et al. (2002) A gene mutated in nephronophthisis and retinitis pigmentosa encodes a novel protein, nephroretinin, conserved in evolution. Am. J. Hum. Genet. 71, 1161-1167.
-
(2002)
Am. J. Hum. Genet.
, vol.71
, pp. 1161-1167
-
-
Otto, E.1
Hoefele, J.2
Ruf, R.3
Mueller, A.M.4
Hiller, K.S.5
Wolf, M.T.6
-
59
-
-
0031742106
-
Renalretinal syndromes: association of retinal anomalies and recessive nephronophthisis in patients with homozygous deletion of the NPH1 locus
-
Caridi, G., Murer, L., Bellantuono, R., Sorino, P., Caringella, D.A., Gusmano, R. et al. (1998) Renalretinal syndromes: association of retinal anomalies and recessive nephronophthisis in patients with homozygous deletion of the NPH1 locus. Am. J. Kidney Dis. 32, 1059-1062.
-
(1998)
Am. J. Kidney Dis.
, vol.32
, pp. 1059-1062
-
-
Caridi, G.1
Murer, L.2
Bellantuono, R.3
Sorino, P.4
Caringella, D.A.5
Gusmano, R.6
-
60
-
-
0036509712
-
The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein
-
Ward, C.J., Hogan, M.C., Rossetti, S., Walker, D., Sneddon, T., Wang, X. et al. (2002) The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein. Nat. Genet. 30, 259-269.
-
(2002)
Nat. Genet.
, vol.30
, pp. 259-269
-
-
Ward, C.J.1
Hogan, M.C.2
Rossetti, S.3
Walker, D.4
Sneddon, T.5
Wang, X.6
-
61
-
-
0033365058
-
Loss-offunction mutations in a human gene related to Chlamydomonas reinhardtii dynein IC78 result in primary ciliary dyskinesia
-
Pennarun, G., Escudier, E., Chapelin, C., Bridoux, A.M., Cacheux, V., Roger, G. et al. (1999) Loss-offunction mutations in a human gene related to Chlamydomonas reinhardtii dynein IC78 result in primary ciliary dyskinesia. Am. J. Hum. Genet. 65, 1508-1519.
-
(1999)
Am. J. Hum. Genet.
, vol.65
, pp. 1508-1519
-
-
Pennarun, G.1
Escudier, E.2
Chapelin, C.3
Bridoux, A.M.4
Cacheux, V.5
Roger, G.6
-
62
-
-
0036479029
-
Mutations in DNAH5 cause primary ciliary dyskinesia and randomization of left-right asymmetry
-
Olbrich, H., Haffner, K., Kispert, A., Volkel, A., Volz, A., Sasmaz, G. et al. (2002) Mutations in DNAH5 cause primary ciliary dyskinesia and randomization of left-right asymmetry. Nat. Genet. 30, 143-144.
-
(2002)
Nat. Genet.
, vol.30
, pp. 143-144
-
-
Olbrich, H.1
Haffner, K.2
Kispert, A.3
Volkel, A.4
Volz, A.5
Sasmaz, G.6
-
63
-
-
0036699538
-
Identification of the gene (BBS1) most commonly involved in Bardet-Biedl syndrome, a complex human obesity syndrome
-
Mykytyn, K., Nishimura, D.Y., Searby, C.C., Shastri, M., Yen, H.J., Beck, J.S. et al. (2002) Identification of the gene (BBS1) most commonly involved in Bardet-Biedl syndrome, a complex human obesity syndrome. Nat. Genet. 31, 435-438.
-
(2002)
Nat. Genet.
, vol.31
, pp. 435-438
-
-
Mykytyn, K.1
Nishimura, D.Y.2
Searby, C.C.3
Shastri, M.4
Yen, H.J.5
Beck, J.S.6
-
64
-
-
0037371508
-
Identification of a novel Bardet-Biedl syndrome protein, BBS7, that shares structural features with BBS1 and BBS2
-
Badano, J.L., Ansley, S.J., Leitch, C.C., Lewis, R.A., Lupski, J.R. and Katsanis, N. (2003) Identification of a novel Bardet-Biedl syndrome protein, BBS7, that shares structural features with BBS1 and BBS2. Am. J. Hum. Genet. 72, 650-658.
-
(2003)
Am. J. Hum. Genet.
, vol.72
, pp. 650-658
-
-
Badano, J.L.1
Ansley, S.J.2
Leitch, C.C.3
Lewis, R.A.4
Lupski, J.R.5
Katsanis, N.6
-
65
-
-
0034967274
-
Identification of the gene that, when mutated, causes the human obesity syndrome BBS4
-
Mykytyn, K., Braun, T., Carmi, R., Haider, N.B., Searby, C.C., Shastri, M. et al. (2001) Identification of the gene that, when mutated, causes the human obesity syndrome BBS4. Nat. Genet. 28, 188-191.
-
(2001)
Nat. Genet.
, vol.28
, pp. 188-191
-
-
Mykytyn, K.1
Braun, T.2
Carmi, R.3
Haider, N.B.4
Searby, C.C.5
Shastri, M.6
-
66
-
-
33646562887
-
Homozygosity mapping with SNP arrays identifies TRIM32, an E3 ubiquitin ligase, as a Bardet-Biedl syndrome gene (BBS11)
-
Chiang, A.P., Beck, J.S., Yen, H.J., Tayeh, M.K., Scheetz, T.E., Swiderski, R.E. et al. (2006) Homozygosity mapping with SNP arrays identifies TRIM32, an E3 ubiquitin ligase, as a Bardet-Biedl syndrome gene (BBS11). Proc. Natl. Acad. Sci. USA 103, 6287-6292.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 6287-6292
-
-
Chiang, A.P.1
Beck, J.S.2
Yen, H.J.3
Tayeh, M.K.4
Scheetz, T.E.5
Swiderski, R.E.6
-
67
-
-
28144460266
-
Comparative genomics and gene expression analysis identifies BBS9, a new Bardet-Biedl syndrome gene
-
Nishimura, D.Y., Swiderski, R.E., Searby, C.C., Berg, E.M., Ferguson, A.L., Hennekam, R. et al. (2005) Comparative genomics and gene expression analysis identifies BBS9, a new Bardet-Biedl syndrome gene. Am. J. Hum. Genet. 77, 1021-1033.
-
(2005)
Am. J. Hum. Genet.
, vol.77
, pp. 1021-1033
-
-
Nishimura, D.Y.1
Swiderski, R.E.2
Searby, C.C.3
Berg, E.M.4
Ferguson, A.L.5
Hennekam, R.6
-
68
-
-
33845995129
-
Identi-fication of a novel BBS gene (BBS12) highlights the major role of a vertebrate-specific branch of chaperonin-related proteins in Bardet-Biedl syndrome
-
Stoetzel, C., Muller, J., Laurier, V., Davis, E.E., Zaghloul, N.A., Vicaire, S. et al. (2007) Identi-fication of a novel BBS gene (BBS12) highlights the major role of a vertebrate-specific branch of chaperonin-related proteins in Bardet-Biedl syndrome. Am. J. Hum. Genet. 80, 1-11.
-
(2007)
Am. J. Hum. Genet.
, vol.80
, pp. 1-11
-
-
Stoetzel, C.1
Muller, J.2
Laurier, V.3
Davis, E.E.4
Zaghloul, N.A.5
Vicaire, S.6
-
69
-
-
31744435454
-
MKS1, encoding a component of the flagellar apparatus basal body proteome, is mutated in Meckel syndrome
-
Kyttala, M., Tallila, J., Salonen, R., Kopra, O., Kohlschmidt, N., Paavola-Sakki, P. et al. (2006) MKS1, encoding a component of the flagellar apparatus basal body proteome, is mutated in Meckel syndrome. Nat. Genet. 38, 155-157.
-
(2006)
Nat. Genet.
, vol.38
, pp. 155-157
-
-
Kyttala, M.1
Tallila, J.2
Salonen, R.3
Kopra, O.4
Kohlschmidt, N.5
Paavola-Sakki, P.6
-
70
-
-
31744441248
-
The transmembrane protein meckelin (MKS3) is mutated in Meckel-Gruber syndrome and the wpk rat
-
Smith, U.M., Consugar, M., Tee, L.J., McKee, B.M., Maina, E.N., Whelan, S. et al. (2006) The transmembrane protein meckelin (MKS3) is mutated in Meckel-Gruber syndrome and the wpk rat. Nat. Genet. 38, 191-196.
-
(2006)
Nat. Genet.
, vol.38
, pp. 191-196
-
-
Smith, U.M.1
Consugar, M.2
Tee, L.J.3
McKee, B.M.4
Maina, E.N.5
Whelan, S.6
-
71
-
-
0035097904
-
Identification of the gene for oral-facial-digital type I syndrome
-
Ferrante, M.I., Giorgio, G., Feather, S.A., Bulfone, A., Wright, V., Ghiani, M. et al. (2001) Identification of the gene for oral-facial-digital type I syndrome. Am. J. Hum. Genet, 68, 569-576.
-
(2001)
Am. J. Hum. Genet.
, vol.68
, pp. 569-576
-
-
Ferrante, M.I.1
Giorgio, G.2
Feather, S.A.3
Bulfone, A.4
Wright, V.5
Ghiani, M.6
-
72
-
-
15844378213
-
A gene (RPGR) with homology to the RCC1 guanine nucleotide exchange factor is mutated in X-linked retinitis pigmentosa (RP3)
-
Meindl, A., Dry, K., Herrmann, K., Manson, F., Ciccodicola, A., Edgar, A. et al. (1996) A gene (RPGR) with homology to the RCC1 guanine nucleotide exchange factor is mutated in X-linked retinitis pigmentosa (RP3). Nat. Genet. 13, 35-42.
-
(1996)
Nat. Genet.
, vol.13
, pp. 35-42
-
-
Meindl, A.1
Dry, K.2
Herrmann, K.3
Manson, F.4
Ciccodicola, A.5
Edgar, A.6
-
73
-
-
0036678117
-
Mutations in the DNAH11 (axonemal heavy chain dynein type 11) gene cause one form of situs inversus totalis and most likely primary ciliary dyskinesia
-
Bartoloni, L., Blouin, J.L., Pan, Y., Gehrig, C., Maiti, A.K., Scamuffa, N. et al. (2002) Mutations in the DNAH11 (axonemal heavy chain dynein type 11) gene cause one form of situs inversus totalis and most likely primary ciliary dyskinesia. Proc. Natl. Acad. Sci. USA 99, 10282-10286.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 10282-10286
-
-
Bartoloni, L.1
Blouin, J.L.2
Pan, Y.3
Gehrig, C.4
Maiti, A.K.5
Scamuffa, N.6
-
74
-
-
34047261773
-
Mutations in VANGL1 associated with neural-tube defects
-
Kibar, Z., Torban, E., McDearmid, J.R., Reynolds, A., Berghout, J., Mathieu, M. et al. (2007) Mutations in VANGL1 associated with neural-tube defects. N. Engl. J. Med. 356, 1432-1437.
-
(2007)
N. Engl. J. Med.
, vol.356
, pp. 1432-1437
-
-
Kibar, Z.1
Torban, E.2
McDearmid, J.R.3
Reynolds, A.4
Berghout, J.5
Mathieu, M.6
|